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M. tuberculosis H37Rv Rv2980 (-)

annotation: POSSIBLE CONSERVED SECRETED PROTEIN
coordinates: 3335960 - 3336505
length: 181

VTGESDGPPRAVLIAAAALAAAVIGVILVVAANRQPPERPVVIPAVPAPQATGPGCKALLAALPQRLGEY
RRAPVAEPTTAGATAWRTGPNSTPVILRCGLDRPAEFVVGSAIQVVDRVQWFQVAAQNPDEPGRSTWYTV
DRPVYVALTLPSGSGPTAIQELSDVIDHTIPAVPIDPAPAR
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv2980--100% (181)POSSIBLE CONSERVED SECRETED PROTEIN

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3004-1e-102100.00% (181) hypothetical protein Mb3004
M. gilvum PYR-GCKMflv_4218-5e-5152.85% (193) hypothetical protein Mflv_4218
M. leprae Br4923MLBr_01677-3e-6466.67% (177) putative secreted protein
M. abscessus ATCC 19977MAB_3285-2e-3443.26% (178) hypothetical protein MAB_3285
M. marinum MMMAR_1734-1e-6565.38% (182) hypothetical protein MMAR_1734
M. avium 104MAV_3831-2e-6466.29% (175) hypothetical protein MAV_3831
M. smegmatis MC2 155MSMEG_2396-7e-5453.44% (189) hypothetical protein MSMEG_2396
M. thermoresistible (build 8)TH_2050-4e-5458.89% (180) POSSIBLE CONSERVED SECRETED PROTEIN
M. ulcerans Agy99MUL_1977-3e-6564.84% (182) hypothetical protein MUL_1977
M. vanbaalenii PYR-1Mvan_2149-2e-4749.76% (205) hypothetical protein Mvan_2149

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_4218|M.gilvum_PYR-GCK          --------------MDSET-------ADGPPRAVLIAAAAV-AVGAVVAL
Mvan_2149|M.vanbaalenii_PYR-1       --------------MSSES-------TDGPPRAALIASLIV-AVGGLVAV
Rv2980|M.tuberculosis_H37Rv         --------------MTGES--------DGPPRAVLIAAAAL-AAAVIGVI
Mb3004|M.bovis_AF2122/97            --------------MTGES--------DGPPRAVLIAAAAL-AAAVIGVI
MLBr_01677|M.leprae_Br4923          --------------MTSNSDAGSAVDAGGPPRTVIIAAVVL-TAATIGTI
MAV_3831|M.avium_104                --------------MATESEAD-----GGPPRAVIMVAVAL-AVTTIGVI
MMAR_1734|M.marinum_M               MGQESRVEPEVSDAVTGDTPASPQPDPDGPPRVLIIAAALL-AVAALGTI
MUL_1977|M.ulcerans_Agy99           --------------MTGDTPANPQPDPDGPPRVLIIAAALL-AVAALGTI
MSMEG_2396|M.smegmatis_MC2_155      --------------------MTDPHTTDGPPRALLIAAVVV-AVSVLITV
TH_2050|M.thermoresistible__bu      ----------VADKSHGESHEIAPEEPDAPPRALLIAAIAV-AVVAVVAI
MAB_3285|M.abscessus_ATCC_1997      --------------MQSED---------GPPRKLLIGIAVFGAIAALAVL
                                                                .***  ::    . :   : .:

Mflv_4218|M.gilvum_PYR-GCK          LIVVAVMQREPAQKPVAVSGIPAPQADSPQCRSLVEALP-EQLGDYRRAQ
Mvan_2149|M.vanbaalenii_PYR-1       LVVAAVLQRTPEPQPVAIAGIPAPRAESPQCRALVDALP-DQLGDYRRAA
Rv2980|M.tuberculosis_H37Rv         LVVAANRQPPE--RPVVIPAVPAPQATGPGCKALLAALP-QRLGEYRRAP
Mb3004|M.bovis_AF2122/97            LVVAANRQPPE--RPVVIPAVPAPQATGPGCKALLAALP-QRLGEYRRAP
MLBr_01677|M.leprae_Br4923          LVLAATLHEPP--QPVVITAVPAPQATTAACRSLTQALP-QRLGDYERAP
MAV_3831|M.avium_104                LAIAATREAPP--QPVAVAAFPAPHAGDAACRALLDALP-QRLGDYQRAP
MMAR_1734|M.marinum_M               LVIAANREVPR--QPVAVPSVPAPQAASPACHALLTALP-QRLGDYQRAP
MUL_1977|M.ulcerans_Agy99           LVIAANREVPR--QPVAVPSVPAPQAASPACHALLTALP-QRLGDYQRAP
MSMEG_2396|M.smegmatis_MC2_155      LGIAASHKQSPEQEPVAISSVPAPQADSPECHALMDGLP-EQLGDFRRAP
TH_2050|M.thermoresistible__bu      LAVAASRQGDPARQPVAIAAVPAPHADDPGCQELLDALP-EQLGDFERAP
MAB_3285|M.abscessus_ATCC_1997      FGVLKYAQFQNETRPLSVANIPAPQANSPLCVDMASAYPGKMAGDWSRVE
                                    : :    .     .*: :. .***:*  . *  :  . * .  *:: *. 

Mflv_4218|M.gilvum_PYR-GCK          LVEPAPQGAAAWQPEAPDGEALILRCGLDRPAEFVTGAPLQVVDAVSWFR
Mvan_2149|M.vanbaalenii_PYR-1       LLEPAPPGTAAWQREEPGSEALILRCGLDRPAEFVAGAPVQVVDAVEWFR
Rv2980|M.tuberculosis_H37Rv         VAEPTTAGATAWRT-GPNSTPVILRCGLDRPAEFVVGSAIQVVDRVQWFQ
Mb3004|M.bovis_AF2122/97            VAEPTTAGATAWRT-GPNSTPVILRCGLDRPAEFVVGSAIQVVDRVQWFQ
MLBr_01677|M.leprae_Br4923          VAQPAPDAVAAWRT-GSDTEPVVLRCGLDGPAEFVVGSPIQAVDQVQWFE
MAV_3831|M.avium_104                LEQPAPAGAAAWRT-GPDSEPVVLRCGLDRPAEFVAGSPIQVVDRVQWFA
MMAR_1734|M.marinum_M               MVQPAPQGTGAWSS-AAADEPVILRCGLDRPADFVVGSPIQVVDRVQWFR
MUL_1977|M.ulcerans_Agy99           MVQPAPQGTGAWSS-AAADEPVILRCGLDRPADFVVGSPIQVVDRVQWFR
MSMEG_2396|M.smegmatis_MC2_155      TVEPTPQGTAAWRG-AADMEPIILRCGLERPVDFVVGAPLQVVDLVQWFR
TH_2050|M.thermoresistible__bu      TVDPAPAGTAAWRR-GDD--TVILRCGLDRPADFVVGAPLQMVDDVQWFR
MAB_3285|M.abscessus_ATCC_1997      IAEPKPPAAAAWRR---GQDSVIARCGVERPAEFAVGTSVEQVNGVQWFR
                                      :* . .. **        .:: ***:: *.:*..*:.:: *: *.** 

Mflv_4218|M.gilvum_PYR-GCK          VGEAGAGNDRVGEAGAG-----ESGVAD--GDRSTWFAVDRPVYVALTLP
Mvan_2149|M.vanbaalenii_PYR-1       VGEAGAGNDRVGEAGAGNDRVGEAGADDPAGERSTWFAVDRPVYVALTIP
Rv2980|M.tuberculosis_H37Rv         VAAQ-------------------NPDEP---GRSTWYTVDRPVYVALTLP
Mb3004|M.bovis_AF2122/97            VAAQ-------------------NPDEP---GRSTWYTVDRPVYVALTLP
MLBr_01677|M.leprae_Br4923          VDAKP-----------------KPAIDA---GRSTWYTVDRPVYVALTLP
MAV_3831|M.avium_104                VRPDP-----------------QSAGDA---GRSTWYTVDRPVYVALTLP
MMAR_1734|M.marinum_M               VSDQT-----------------EAAGTATAGSRSTWYTVDRPVYVALTLP
MUL_1977|M.ulcerans_Agy99           VSDQT-----------------EAAGTATAGSRSTWYTVDRPVYVALTLP
MSMEG_2396|M.smegmatis_MC2_155      VGDTGAAQP------------GDADAGAAEDTRSTWYAVDRPVYVALTLP
TH_2050|M.thermoresistible__bu      V---------------------------AEADRTTWYAVDRPLYVALTLP
MAB_3285|M.abscessus_ATCC_1997      VSDSA-------------------------LASTTWFAVDRGVYVAVTVP
                                    *                                :**::*** :***:*:*

Mflv_4218|M.gilvum_PYR-GCK          RDSGPTAIQTLSTIIAETLPAQTPQPAPLG-
Mvan_2149|M.vanbaalenii_PYR-1       ADSGPTPIQTLSKIIADTLQSRPPDPAPIG-
Rv2980|M.tuberculosis_H37Rv         SGSGPTAIQELSDVIDHTIPAVPIDPAPAR-
Mb3004|M.bovis_AF2122/97            SGSGPTAIQELSDVIDHTIPAVPIDPAPAR-
MLBr_01677|M.leprae_Br4923          SGSGPTPIQELSDVIDRTLAAIPISPAQSH-
MAV_3831|M.avium_104                SGSGPAPIQRLSDVIEQRIAAAPVNPGPPAG
MMAR_1734|M.marinum_M               AGSGPTPIQELSEIIDRAIAPVPIDPAPAG-
MUL_1977|M.ulcerans_Agy99           AGSGPTPIQELSEIIDRAIAPAPIDPAPAG-
MSMEG_2396|M.smegmatis_MC2_155      SGSGPTPIQLISGQIARAMPEKPVEPGPAR-
TH_2050|M.thermoresistible__bu      ADSGPSPIQGLSQTIAKVLPAKEIDPAPAR-
MAB_3285|M.abscessus_ATCC_1997      DGAGSEPLVEMSDAIAKALPAVKPDPKPLPR
                                     .:*. .:  :*  *   :     .*