For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. tuberculosis H37Rv Rv2943A (-)

annotation: POSSIBLE TRANSPOSASE
coordinates: 3289705 - 3290235
length: 176

MPTTKATQRRDVSTEIAYLTRALKAPTLRESVSRLADRARAENWSHEEYLAACLQREVSARESHGGEGRI
RAARFPARKSLEEFDFEHARGLKRDTIAHLGTLDFITARDNVVFLGPAWHREDSSCGRPGDTRVSGRSSG
AVRHRRRMGSTARRGSPRRAHLRRTHPALPLSAPGG
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv2943A--100% (176)POSSIBLE TRANSPOSASE
M. tuberculosis H37RvRv3638-6e-4679.44% (107) transposase
M. tuberculosis H37RvRv3427c-7e-0728.87% (97) transposase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2969-1e-100100.00% (176) transposase
M. gilvum PYR-GCKMflv_0579-2e-5083.33% (108) IstB ATP binding domain-containing protein
M. leprae Br4923-----
M. abscessus ATCC 19977-----
M. marinum M-----
M. avium 104MAV_3532-3e-1130.93% (97) helper protein
M. smegmatis MC2 155MSMEG_2150-5e-0930.17% (116) putative transposition helper protein
M. thermoresistible (build 8)TH_1648-1e-0830.17% (116) putative transposition helper protein
M. ulcerans Agy99-----
M. vanbaalenii PYR-1Mvan_0481-2e-5083.33% (108) DNA replication protein-like

CLUSTAL 2.0.9 multiple sequence alignment


Rv2943A|M.tuberculosis_H37Rv        ------MPTTKATQR--------RDVSTEIAYLTRALKAPTLRESVSRLA
Mb2969|M.bovis_AF2122/97            ------MPTTKATQR--------RDVSTEIAYLTRALKAPTLRESVSRLA
Mflv_0579|M.gilvum_PYR-GCK          ------MTTKTATTKTAAASVASRDLTAEIGFLTRALKAPTMREAVARLA
Mvan_0481|M.vanbaalenii_PYR-1       ------MTTKTATTKTAAASVASRDLTAEIGFLTRALKAPTMREAVARLA
MSMEG_2150|M.smegmatis_MC2_155      MTPTPRTAKN-TATVTEEPPSTAASRYQKLRSHLAELKLHAAAAALPAVL
TH_1648|M.thermoresistible__bu      MTPTPRTPKTATTTTVEESPSAAASRYQQLRSHLAELKLAAAAEALPAVL
MAV_3532|M.avium_104                ----------MTTAAKPVAPSSAAPLAADLDAALRRLKLATVRRNAAEVL
                                               ::               .:      **  :     . : 

Rv2943A|M.tuberculosis_H37Rv        DRARAENWSHEEYLAACLQREVSARESHGGEGRIRAARFPARKSLEEFDF
Mb2969|M.bovis_AF2122/97            DRARAENWSHEEYLAACLQREVSARESHGGEGRIRAARFPARKSLEEFDF
Mflv_0579|M.gilvum_PYR-GCK          ERARAESWTHEEFLVACLQREVSARESHGGEGRIRAARFPSRKSLEEFDF
Mvan_0481|M.vanbaalenii_PYR-1       ERARAESWTHEEFLVACLQREVSARESHGGEGRIRAARFPSRKSLEEFDF
MSMEG_2150|M.smegmatis_MC2_155      DQASAENLSLTVALERLLAVEVEASTARRLAGRLRFACLPTPATLDDFDV
TH_1648|M.thermoresistible__bu      DEATAEGLSLTVALERLLAVEVEASTARRLAGRLRFACLPTPATLADFDV
MAV_3532|M.avium_104                QVAKTQRWTPEEILRTLVEAEIAARDASNTANRLKAAAFPVTKTLDGFDV
                                    : * ::  :    *   :  *: *  :    .*:: * :*   :*  **.

Rv2943A|M.tuberculosis_H37Rv        EHARGLKRDTIAHLGTLDFITARDNVVFLGP-------------------
Mb2969|M.bovis_AF2122/97            EHARGLKRDTIAHLGTLDFITARDNVVFLGP-------------------
Mflv_0579|M.gilvum_PYR-GCK          DHARGLKRDTIAHLGTLDFVVAKDNVVFLGPPGTGKTHLAIGIAIRACQA
Mvan_0481|M.vanbaalenii_PYR-1       DHARGLKRDTIAHLGTLDFVVAKDNVVFLGP-------------------
MSMEG_2150|M.smegmatis_MC2_155      DAAAGIDRKLIDELGTCRYLESATNILLVGPPGTGKTHLSVGLARAAAHA
TH_1648|M.thermoresistible__bu      DAAAGIDRKLIDELGTCRYLESATNILLIGPPGTGKTHLSVGLARAAAHA
MAV_3532|M.avium_104                TGSS-ITAATFDYLSSLEWIRAQQNLAVIGPPGTGKSHLLIGCGHAAVHA
                                      :  :    :  *.:  :: :  *: .:**                   

Rv2943A|M.tuberculosis_H37Rv        ----AWHREDSSCGRPGDTRVSGRSSGAVRHRR-----------------
Mb2969|M.bovis_AF2122/97            ----AWHREDSSCGRPGDTRVSGRSSGAVRHRR-----------------
Mflv_0579|M.gilvum_PYR-GCK          GHRVLFATASQWVARLAEAHQGGRLQQELIRLGRYPLLVVDEVGYIPFEP
Mvan_0481|M.vanbaalenii_PYR-1       ---VVIVGS---VARWPHSACSGRCCD-----------------------
MSMEG_2150|M.smegmatis_MC2_155      GYRTYFTTAADLAARCHRAAIEGRWATTMRFYAGPTLLVIDELGYLPLPA
TH_1648|M.thermoresistible__bu      GYRTYFTTAADLAARCHRAAIEGRWATTMRFYAGPTLLVIDELGYLPLPA
MAV_3532|M.avium_104                GFKVRYFTAADLIEVLYRGLADNTVGKIIDTLLRADLVILDEIGFAPLDD
                                                          .                           

Rv2943A|M.tuberculosis_H37Rv        --------------------------------------------------
Mb2969|M.bovis_AF2122/97            --------------------------------------------------
Mflv_0579|M.gilvum_PYR-GCK          EAANLFFQLVSSRYERASLIVTSNKPFGKAHLFARTCAEVALKRDMFAGI
Mvan_0481|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_2150|M.smegmatis_MC2_155      EAASALFQVVSQRYLKTSIVITTNRGVGSWG------------EILGDTT
TH_1648|M.thermoresistible__bu      EAASALFQVVSQRYLKTSIVITTNRGVGAWG------------EILGDTT
MAV_3532|M.avium_104                TGTQLLFRLVAAGYERRSLAIASHWPFEQWG------------RFLPEHT
                                                                                      

Rv2943A|M.tuberculosis_H37Rv        RMGSTARRGSPRR-------AHLRRTHPALPLSAPGG----------
Mb2969|M.bovis_AF2122/97            RMGSTARRGSPRR-------AHLRRTHPALPLSAPGG----------
Mflv_0579|M.gilvum_PYR-GCK          RVGRGGRAVGPRRGDRRDRSSLLRVSSRRLPRRVSGRSY--------
Mvan_0481|M.vanbaalenii_PYR-1       -----------------------------------------------
MSMEG_2150|M.smegmatis_MC2_155      VAAAMLDRLLHRSVVINLDGESYRLRDHQAAAETLRRATTGTRQALH
TH_1648|M.thermoresistible__bu      VAAAMLDRLLHRSVVINLDGESYRLRDHQAAAETLRRTTTGTRQPLH
MAV_3532|M.avium_104                TAASILDRLLHHASIVVTSGESYRMRHADHKKGAAKN----------