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M. tuberculosis H37Rv Rv2793c (truB)

annotation: tRNA pseudouridine synthase B
coordinates: 3102364 - 3103260
length: 298

SATGPGIVVIDKPAGMTSHDVVGRCRRIFATRRVGHAGTLDPMATGVLVIGIERATKILGLLTAAPKSYA
ATIRLGQTTSTEDAEGQVLQSVPAKHLTIEAIDAAMERLRGEIRQVPSSVSAIKVGGRRAYRLARQGRSV
QLEARPIRIDRFELLAARRRDQLIDIDVEIDCSSGTYIRALARDLGDALGVGGHVTALRRTRVGRFELDQ
ARSLDDLAERPALSLSLDEACLLMFARRDLTAAEASAAANGRSLPAVGIDGVYAACDADGRVIALLRDEG
SRTRSVAVLRPATMHPG*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv2793ctruB-100% (298)tRNA pseudouridine synthase B

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2816ctruB1e-164100.00% (298) tRNA pseudouridine synthase B
M. gilvum PYR-GCKMflv_4028truB1e-11269.66% (290) tRNA pseudouridine synthase B
M. leprae Br4923MLBr_01546truB1e-12174.06% (293) tRNA pseudouridine synthase B
M. abscessus ATCC 19977MAB_3116ctruB1e-11271.03% (290) tRNA pseudouridine synthase B
M. marinum MMMAR_1917truB1e-12477.32% (291) tRNA pseudouridine synthase B TruB
M. avium 104MAV_3682truB1e-12373.03% (304) tRNA pseudouridine synthase B
M. smegmatis MC2 155MSMEG_2649truB1e-11670.37% (297) tRNA pseudouridine synthase B
M. thermoresistible (build 8)-----
M. ulcerans Agy99MUL_2142truB1e-12276.29% (291) tRNA pseudouridine synthase B
M. vanbaalenii PYR-1Mvan_2329truB1e-12073.79% (290) tRNA pseudouridine synthase B

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_4028|M.gilvum_PYR-GCK          --------MSAEPGLVVVDKPGGMTSHDVVGRCRRLFGTRKVGHAGTLDP
Mvan_2329|M.vanbaalenii_PYR-1       MTEGAHPRNNPAPGLVVVDKPGGMTSHDVVGRCRRLFGTRKVGHAGTLDP
MSMEG_2649|M.smegmatis_MC2_155      --MSGQARSGAEPGLVIVDKPAGMTSHDVVGRCRRLFGTRKVGHAGTLDP
MAB_3116c|M.abscessus_ATCC_199      -----MTDPLSRAGLVIVDKPAGMTSHDVVSRCRRIFSTRKVGHAGTLDP
MAV_3682|M.avium_104                ---------MSPPGLVVVDKPAGMTSHDVVGRCRRIFATRRVGHAGTLDP
Rv2793c|M.tuberculosis_H37Rv        -MSAT------GPGIVVIDKPAGMTSHDVVGRCRRIFATRRVGHAGTLDP
Mb2816c|M.bovis_AF2122/97           -MSAT------GPGIVVIDKPAGMTSHDVVGRCRRIFATRRVGHAGTLDP
MMAR_1917|M.marinum_M               -MSRQNAGPGFGPGIVVVDKPGAMTSHDVVGRCRRIFGTRRVGHAGTLDP
MUL_2142|M.ulcerans_Agy99           -MSRQNAGPGFGPGIVVVDKPGAMTSHDVVGRCRRIFGTRRLGHAGTLDP
MLBr_01546|M.leprae_Br4923          -MSESSTGAGLGPGIVVIDKPSGMTSHDVVARCRRIFCTRRVGHAGTLDP
                                                .*:*::***..*******.****:* **::********

Mflv_4028|M.gilvum_PYR-GCK          MATGVLVIGIERATKILGLLTATDKSYTATLRLGQTTSTEDTEGELLHQV
Mvan_2329|M.vanbaalenii_PYR-1       MATGVLVVGIERATKILGLLTATDKSYAATIRLGQTTSTEDAEGEVLQSV
MSMEG_2649|M.smegmatis_MC2_155      MATGVLVIGIERATKILGLLTATDKSYAATIRLGRTTTTEDAEGEVVEDV
MAB_3116c|M.abscessus_ATCC_199      MATGVLVIGIERATKIMGLLTLTTKSYAATIRFGQSTSTDDAEGEVLQTI
MAV_3682|M.avium_104                MATGVLVLGVERATKILGLLTAAAKSYSATIRLGQATSTDDAEGDVVRSV
Rv2793c|M.tuberculosis_H37Rv        MATGVLVIGIERATKILGLLTAAPKSYAATIRLGQTTSTEDAEGQVLQSV
Mb2816c|M.bovis_AF2122/97           MATGVLVIGIERATKILGLLTAAPKSYAATIRLGQTTSTEDAEGQVLQSV
MMAR_1917|M.marinum_M               MATGVLVIGIERATKILGLLTATSKSYAATIRLGQTTSTEDAEGEPLASV
MUL_2142|M.ulcerans_Agy99           MATGVLVIGIERATKILGLLIATSKSYAATIRLGQTTSTEDAEGEPLASV
MLBr_01546|M.leprae_Br4923          MATGVLVLGVDRATKILGLLAGASKEYVATIRLGQTTSTEDAEGELLQCV
                                    *******:*::*****:***  : *.* **:*:*::*:*:*:**: :  :

Mflv_4028|M.gilvum_PYR-GCK          SAAQVTDEQIERAIAPLRGAIEQVPSAVSAIKIAGKRAYQMVRDGEQVEI
Mvan_2329|M.vanbaalenii_PYR-1       SAAEVTDAQIEAAIAPLRGPIDQIPSAVSAIKIAGKRAYQMVRDGQTVEL
MSMEG_2649|M.smegmatis_MC2_155      PARRVTDEQIHAAVADLRGDIEQVPSAVSAIKVGGQRAYKLAREGQSVEL
MAB_3116c|M.abscessus_ATCC_199      SASHLTEVDIEAAVAGLRGDIAQVPSSVSAIKVDGQRAYKLAREGQSVEL
MAV_3682|M.avium_104                DARHLTSQAIEAAVGGLRGDIHQVPSTVSAIKVAGKRAYKLVREGQAVEL
Rv2793c|M.tuberculosis_H37Rv        PAKHLTIEAIDAAMERLRGEIRQVPSSVSAIKVGGRRAYRLARQGRSVQL
Mb2816c|M.bovis_AF2122/97           PAKHLTIEAIDAAMERLRGEIRQVPSSVSAIKVGGRRAYRLARQGRSVQL
MMAR_1917|M.marinum_M               SAEHVAPEAIAAAILDLTGDIRQVPSAVSAIKVDGRRAYQLAREGQTVEL
MUL_2142|M.ulcerans_Agy99           SAEHVAPEAIAAAILDLTGDIRQVPSAVSAIKVDGRRAYQLAREGQTVEL
MLBr_01546|M.leprae_Br4923          SARHVTDEAIATAIGRLRGDIKQVPSAVSAIKVDGRRAYRLVREGHVVEL
                                     * .::   *  *:  * * * *:**:*****: *:***::.*:*. *::

Mflv_4028|M.gilvum_PYR-GCK          PARPVRIDRFEVLAVRRNG-----DVVDVDVVVDCSSGTYIRALARDVGA
Mvan_2329|M.vanbaalenii_PYR-1       AARPVRIDRFEVLEVRRDG-----ELVDVDVAVDCSSGTYIRALARDVGA
MSMEG_2649|M.smegmatis_MC2_155      AARPVRIDRFDVLDIRRPDDF--PDFVDVDVEVDCSSGTYIRALARDVGA
MAB_3116c|M.abscessus_ATCC_199      AARPVRISRFDVLAVRGSGE----DLIDVDVEIDCSSGTYIRALARDAGA
MAV_3682|M.avium_104                PARPVRIDRFEVRDLRAAG-----ECVDVDVEVDCSSGTYVRALARDLGA
Rv2793c|M.tuberculosis_H37Rv        EARPIRIDRFELLAARRR-----DQLIDIDVEIDCSSGTYIRALARDLGD
Mb2816c|M.bovis_AF2122/97           EARPIRIDRFELLAARRR-----DQLIDIDVEIDCSSGTYIRALARDLGD
MMAR_1917|M.marinum_M               AARPVRIDRFELMDLRRG-----ADVIDIDVEVDCSSGTYIRALARDLGA
MUL_2142|M.ulcerans_Agy99           AARPVRIDRFELMDLRRG-----ADVIDIDVEVDCSSGTYIRALARDLGA
MLBr_01546|M.leprae_Br4923          QARPVRIDRFEVLAVRPGPEVGLADVIDLDVEVECSSGTYIRALARDLGD
                                     ***:**.**::   *        : :*:** ::******:****** * 

Mflv_4028|M.gilvum_PYR-GCK          ALGVGGHLTALRRTRVGGFGLDQARTLEQLADAAELSYSLDEACLHAFPR
Mvan_2329|M.vanbaalenii_PYR-1       ALGVGGHLTALRRTRVGGFGLEQARTLDELAEAPRLSYSLDEACLRAFAR
MSMEG_2649|M.smegmatis_MC2_155      ALGVGGHLTVLRRTRVGRYGLDEAHTLDELAEHPQLSYSLDTACLVGFPR
MAB_3116c|M.abscessus_ATCC_199      ALGVGGHLTALRRTRVGDFGLDRARTLEELADGATLTLDLDSACRQGFPR
MAV_3682|M.avium_104                ALGVGGHLTALRRTRVGRFGLEQAYGLDELAECPRLSYSLDEACLLIFGR
Rv2793c|M.tuberculosis_H37Rv        ALGVGGHVTALRRTRVGRFELDQARSLDDLAERPALSLSLDEACLLMFAR
Mb2816c|M.bovis_AF2122/97           ALGVGGHVTALRRTRVGRFELDQARSLDDLAERPALSLSLDEACLLMFAR
MMAR_1917|M.marinum_M               ALDVGGHLTSLRRTRVGHFDLSQAASLDELAERPALSLTLDQACLLMFPR
MUL_2142|M.ulcerans_Agy99           ALDVGGHLTSLRRTRVSHFDLSQAASLDELAERPALSLTLDQACLLMFPR
MLBr_01546|M.leprae_Br4923          AFGVGGHLTSLRRTRVGRFELDQAWSLEDLAELPRLSRTLDETCLLMFPR
                                    *:.****:* ******. : *..*  *::**: . *:  ** :*   * *

Mflv_4028|M.gilvum_PYR-GCK          RELTDAEVVDAGHG-----------RSLAPAGIDGVYAATAPDGRVMALL
Mvan_2329|M.vanbaalenii_PYR-1       RDITEAEAESASHG-----------RALPVAGIDGVYAATAPDGRVIALL
MSMEG_2649|M.smegmatis_MC2_155      RDLSAEETEDTRHG-----------RPLRPAGIDGVYAATAPDGRVIALL
MAB_3116c|M.abscessus_ATCC_199      RDLDAAEVDAVRNG-----------RPLAPAGIEGTYAAVDADDRVIALL
MAV_3682|M.avium_104                RDLSADEAEAAGNGRALAAAAAGNGRALAAAGIDGVYAACAPDGRVIALL
Rv2793c|M.tuberculosis_H37Rv        RDLTAAEASAAANG-----------RSLPAVGIDGVYAACDADGRVIALL
Mb2816c|M.bovis_AF2122/97           RDLTAAEASAAANG-----------RSLPAVGIDGVYAACDADGRVIALL
MMAR_1917|M.marinum_M               RDLTVDESQSVGNG-----------RPLEPAGIDGIYAASDADGRVIALL
MUL_2142|M.ulcerans_Agy99           RDLTVDESQSVGNG-----------RPLEPAGIDGIYAASDADGRVIALL
MLBr_01546|M.leprae_Br4923          RDLTVSEVEATSNG-----------RPISSAGIDGIYAASDADGRVIALL
                                    *::   *   . :*           *.:  .**:* ***  .*.**:***

Mflv_4028|M.gilvum_PYR-GCK          EDAGPRTRSVVVIRPATL--------------
Mvan_2329|M.vanbaalenii_PYR-1       SDEGDRTRSVVVLRPATL--------------
MSMEG_2649|M.smegmatis_MC2_155      QDGAGRTRNVVVLRPATL--------------
MAB_3116c|M.abscessus_ATCC_199      ADKGSRTTSVVVLRPANL--------------
MAV_3682|M.avium_104                RDEGARTRSVVVIRPATMQDGTS---------
Rv2793c|M.tuberculosis_H37Rv        RDEGSRTRSVAVLRPATMHPG-----------
Mb2816c|M.bovis_AF2122/97           RDEGSRTRSVAVLRPATMHPG-----------
MMAR_1917|M.marinum_M               RDEGRRTKSVVVIRPATM--------------
MUL_2142|M.ulcerans_Agy99           RDEGRRTKSVVVIRPATM--------------
MLBr_01546|M.leprae_Br4923          RDEGPRTKSVVVLHPVFVRVSIGRGIVGVIEA
                                     * . ** .*.*::*. :