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SESSTGAGLGPGIVVIDKPSGMTSHDVVARCRRIFCTRRVGHAGTLDPMATGVLVLGVDRATKILGLLAG ASKEYVATIRLGQTTSTEDAEGELLQCVSARHVTDEAIATAIGRLRGDIKQVPSAVSAIKVDGRRAYRLV REGHVVELQARPVRIDRFEVLAVRPGPEVGLADVIDLDVEVECSSGTYIRALARDLGDAFGVGGHLTSLR RTRVGRFELDQAWSLEDLAELPRLSRTLDETCLLMFPRRDLTVSEVEATSNGRPISSAGIDGIYAASDAD GRVIALLRDEGPRTKSVVVLHPVFVRVSIGRGIVGVIEA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. leprae Br4923 | MLBr_01546 | truB | - | 100% (320) | tRNA pseudouridine synthase B |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2816c | truB | 1e-121 | 74.06% (293) | tRNA pseudouridine synthase B |
| M. gilvum PYR-GCK | Mflv_4028 | truB | 1e-109 | 68.84% (292) | tRNA pseudouridine synthase B |
| M. tuberculosis H37Rv | Rv2793c | truB | 1e-121 | 74.06% (293) | tRNA pseudouridine synthase B |
| M. abscessus ATCC 19977 | MAB_3116c | truB | 1e-107 | 67.70% (291) | tRNA pseudouridine synthase B |
| M. marinum M | MMAR_1917 | truB | 1e-124 | 75.91% (303) | tRNA pseudouridine synthase B TruB |
| M. avium 104 | MAV_3682 | truB | 1e-113 | 68.98% (303) | tRNA pseudouridine synthase B |
| M. smegmatis MC2 155 | MSMEG_2649 | truB | 1e-110 | 67.23% (296) | tRNA pseudouridine synthase B |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_2142 | truB | 1e-123 | 75.25% (303) | tRNA pseudouridine synthase B |
| M. vanbaalenii PYR-1 | Mvan_2329 | truB | 1e-110 | 69.52% (292) | tRNA pseudouridine synthase B |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4028|M.gilvum_PYR-GCK --------MSAEPGLVVVDKPGGMTSHDVVGRCRRLFGTRKVGHAGTLDP
Mvan_2329|M.vanbaalenii_PYR-1 MTEGAHPRNNPAPGLVVVDKPGGMTSHDVVGRCRRLFGTRKVGHAGTLDP
MSMEG_2649|M.smegmatis_MC2_155 --MSGQARSGAEPGLVIVDKPAGMTSHDVVGRCRRLFGTRKVGHAGTLDP
MAB_3116c|M.abscessus_ATCC_199 -----MTDPLSRAGLVIVDKPAGMTSHDVVSRCRRIFSTRKVGHAGTLDP
MAV_3682|M.avium_104 ---------MSPPGLVVVDKPAGMTSHDVVGRCRRIFATRRVGHAGTLDP
MMAR_1917|M.marinum_M -MSRQNAGPGFGPGIVVVDKPGAMTSHDVVGRCRRIFGTRRVGHAGTLDP
MUL_2142|M.ulcerans_Agy99 -MSRQNAGPGFGPGIVVVDKPGAMTSHDVVGRCRRIFGTRRLGHAGTLDP
MLBr_01546|M.leprae_Br4923 -MSESSTGAGLGPGIVVIDKPSGMTSHDVVARCRRIFCTRRVGHAGTLDP
Mb2816c|M.bovis_AF2122/97 -MSAT------GPGIVVIDKPAGMTSHDVVGRCRRIFATRRVGHAGTLDP
Rv2793c|M.tuberculosis_H37Rv -MSAT------GPGIVVIDKPAGMTSHDVVGRCRRIFATRRVGHAGTLDP
.*:*::***..*******.****:* **::********
Mflv_4028|M.gilvum_PYR-GCK MATGVLVIGIERATKILGLLTATDKSYTATLRLGQTTSTEDTEGELLHQV
Mvan_2329|M.vanbaalenii_PYR-1 MATGVLVVGIERATKILGLLTATDKSYAATIRLGQTTSTEDAEGEVLQSV
MSMEG_2649|M.smegmatis_MC2_155 MATGVLVIGIERATKILGLLTATDKSYAATIRLGRTTTTEDAEGEVVEDV
MAB_3116c|M.abscessus_ATCC_199 MATGVLVIGIERATKIMGLLTLTTKSYAATIRFGQSTSTDDAEGEVLQTI
MAV_3682|M.avium_104 MATGVLVLGVERATKILGLLTAAAKSYSATIRLGQATSTDDAEGDVVRSV
MMAR_1917|M.marinum_M MATGVLVIGIERATKILGLLTATSKSYAATIRLGQTTSTEDAEGEPLASV
MUL_2142|M.ulcerans_Agy99 MATGVLVIGIERATKILGLLIATSKSYAATIRLGQTTSTEDAEGEPLASV
MLBr_01546|M.leprae_Br4923 MATGVLVLGVDRATKILGLLAGASKEYVATIRLGQTTSTEDAEGELLQCV
Mb2816c|M.bovis_AF2122/97 MATGVLVIGIERATKILGLLTAAPKSYAATIRLGQTTSTEDAEGQVLQSV
Rv2793c|M.tuberculosis_H37Rv MATGVLVIGIERATKILGLLTAAPKSYAATIRLGQTTSTEDAEGQVLQSV
*******:*::*****:*** : *.* **:*:*::*:*:*:**: : :
Mflv_4028|M.gilvum_PYR-GCK SAAQVTDEQIERAIAPLRGAIEQVPSAVSAIKIAGKRAYQMVRDGEQVEI
Mvan_2329|M.vanbaalenii_PYR-1 SAAEVTDAQIEAAIAPLRGPIDQIPSAVSAIKIAGKRAYQMVRDGQTVEL
MSMEG_2649|M.smegmatis_MC2_155 PARRVTDEQIHAAVADLRGDIEQVPSAVSAIKVGGQRAYKLAREGQSVEL
MAB_3116c|M.abscessus_ATCC_199 SASHLTEVDIEAAVAGLRGDIAQVPSSVSAIKVDGQRAYKLAREGQSVEL
MAV_3682|M.avium_104 DARHLTSQAIEAAVGGLRGDIHQVPSTVSAIKVAGKRAYKLVREGQAVEL
MMAR_1917|M.marinum_M SAEHVAPEAIAAAILDLTGDIRQVPSAVSAIKVDGRRAYQLAREGQTVEL
MUL_2142|M.ulcerans_Agy99 SAEHVAPEAIAAAILDLTGDIRQVPSAVSAIKVDGRRAYQLAREGQTVEL
MLBr_01546|M.leprae_Br4923 SARHVTDEAIATAIGRLRGDIKQVPSAVSAIKVDGRRAYRLVREGHVVEL
Mb2816c|M.bovis_AF2122/97 PAKHLTIEAIDAAMERLRGEIRQVPSSVSAIKVGGRRAYRLARQGRSVQL
Rv2793c|M.tuberculosis_H37Rv PAKHLTIEAIDAAMERLRGEIRQVPSSVSAIKVGGRRAYRLARQGRSVQL
* .:: * *: * * * *:**:*****: *:***::.*:*. *::
Mflv_4028|M.gilvum_PYR-GCK PARPVRIDRFEVLAVRRNG-----DVVDVDVVVDCSSGTYIRALARDVGA
Mvan_2329|M.vanbaalenii_PYR-1 AARPVRIDRFEVLEVRRDG-----ELVDVDVAVDCSSGTYIRALARDVGA
MSMEG_2649|M.smegmatis_MC2_155 AARPVRIDRFDVLDIRRPDDF--PDFVDVDVEVDCSSGTYIRALARDVGA
MAB_3116c|M.abscessus_ATCC_199 AARPVRISRFDVLAVRGSGE----DLIDVDVEIDCSSGTYIRALARDAGA
MAV_3682|M.avium_104 PARPVRIDRFEVRDLRAAG-----ECVDVDVEVDCSSGTYVRALARDLGA
MMAR_1917|M.marinum_M AARPVRIDRFELMDLRRG-----ADVIDIDVEVDCSSGTYIRALARDLGA
MUL_2142|M.ulcerans_Agy99 AARPVRIDRFELMDLRRG-----ADVIDIDVEVDCSSGTYIRALARDLGA
MLBr_01546|M.leprae_Br4923 QARPVRIDRFEVLAVRPGPEVGLADVIDLDVEVECSSGTYIRALARDLGD
Mb2816c|M.bovis_AF2122/97 EARPIRIDRFELLAARRR-----DQLIDIDVEIDCSSGTYIRALARDLGD
Rv2793c|M.tuberculosis_H37Rv EARPIRIDRFELLAARRR-----DQLIDIDVEIDCSSGTYIRALARDLGD
***:**.**:: * : :*:** ::******:****** *
Mflv_4028|M.gilvum_PYR-GCK ALGVGGHLTALRRTRVGGFGLDQARTLEQLADAAELSYSLDEACLHAFPR
Mvan_2329|M.vanbaalenii_PYR-1 ALGVGGHLTALRRTRVGGFGLEQARTLDELAEAPRLSYSLDEACLRAFAR
MSMEG_2649|M.smegmatis_MC2_155 ALGVGGHLTVLRRTRVGRYGLDEAHTLDELAEHPQLSYSLDTACLVGFPR
MAB_3116c|M.abscessus_ATCC_199 ALGVGGHLTALRRTRVGDFGLDRARTLEELADGATLTLDLDSACRQGFPR
MAV_3682|M.avium_104 ALGVGGHLTALRRTRVGRFGLEQAYGLDELAECPRLSYSLDEACLLIFGR
MMAR_1917|M.marinum_M ALDVGGHLTSLRRTRVGHFDLSQAASLDELAERPALSLTLDQACLLMFPR
MUL_2142|M.ulcerans_Agy99 ALDVGGHLTSLRRTRVSHFDLSQAASLDELAERPALSLTLDQACLLMFPR
MLBr_01546|M.leprae_Br4923 AFGVGGHLTSLRRTRVGRFELDQAWSLEDLAELPRLSRTLDETCLLMFPR
Mb2816c|M.bovis_AF2122/97 ALGVGGHVTALRRTRVGRFELDQARSLDDLAERPALSLSLDEACLLMFAR
Rv2793c|M.tuberculosis_H37Rv ALGVGGHVTALRRTRVGRFELDQARSLDDLAERPALSLSLDEACLLMFAR
*:.****:* ******. : *..* *::**: . *: ** :* * *
Mflv_4028|M.gilvum_PYR-GCK RELTDAEVVDAGHG-----------RSLAPAGIDGVYAATAPDGRVMALL
Mvan_2329|M.vanbaalenii_PYR-1 RDITEAEAESASHG-----------RALPVAGIDGVYAATAPDGRVIALL
MSMEG_2649|M.smegmatis_MC2_155 RDLSAEETEDTRHG-----------RPLRPAGIDGVYAATAPDGRVIALL
MAB_3116c|M.abscessus_ATCC_199 RDLDAAEVDAVRNG-----------RPLAPAGIEGTYAAVDADDRVIALL
MAV_3682|M.avium_104 RDLSADEAEAAGNGRALAAAAAGNGRALAAAGIDGVYAACAPDGRVIALL
MMAR_1917|M.marinum_M RDLTVDESQSVGNG-----------RPLEPAGIDGIYAASDADGRVIALL
MUL_2142|M.ulcerans_Agy99 RDLTVDESQSVGNG-----------RPLEPAGIDGIYAASDADGRVIALL
MLBr_01546|M.leprae_Br4923 RDLTVSEVEATSNG-----------RPISSAGIDGIYAASDADGRVIALL
Mb2816c|M.bovis_AF2122/97 RDLTAAEASAAANG-----------RSLPAVGIDGVYAACDADGRVIALL
Rv2793c|M.tuberculosis_H37Rv RDLTAAEASAAANG-----------RSLPAVGIDGVYAACDADGRVIALL
*:: * . :* *.: .**:* *** .*.**:***
Mflv_4028|M.gilvum_PYR-GCK EDAGPRTRSVVVIRPATL--------------
Mvan_2329|M.vanbaalenii_PYR-1 SDEGDRTRSVVVLRPATL--------------
MSMEG_2649|M.smegmatis_MC2_155 QDGAGRTRNVVVLRPATL--------------
MAB_3116c|M.abscessus_ATCC_199 ADKGSRTTSVVVLRPANL--------------
MAV_3682|M.avium_104 RDEGARTRSVVVIRPATMQDGTS---------
MMAR_1917|M.marinum_M RDEGRRTKSVVVIRPATM--------------
MUL_2142|M.ulcerans_Agy99 RDEGRRTKSVVVIRPATM--------------
MLBr_01546|M.leprae_Br4923 RDEGPRTKSVVVLHPVFVRVSIGRGIVGVIEA
Mb2816c|M.bovis_AF2122/97 RDEGSRTRSVAVLRPATMHPG-----------
Rv2793c|M.tuberculosis_H37Rv RDEGSRTRSVAVLRPATMHPG-----------
* . ** .*.*::*. :