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M. ulcerans Agy99 MUL_2142 (truB)

annotation: tRNA pseudouridine synthase B
coordinates: 2390698 - 2391603
length: 301

MSRQNAGPGFGPGIVVVDKPGAMTSHDVVGRCRRIFGTRRLGHAGTLDPMATGVLVIGIERATKILGLLI
ATSKSYAATIRLGQTTSTEDAEGEPLASVSAEHVAPEAIAAAILDLTGDIRQVPSAVSAIKVDGRRAYQL
AREGQTVELAARPVRIDRFELMDLRRGADVIDIDVEVDCSSGTYIRALARDLGAALDVGGHLTSLRRTRV
SHFDLSQAASLDELAERPALSLTLDQACLLMFPRRDLTVDESQSVGNGRPLEPAGIDGIYAASDADGRVI
ALLRDEGRRTKSVVVIRPATM
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. ulcerans Agy99MUL_2142truB-100% (301)tRNA pseudouridine synthase B

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2816ctruB1e-12276.29% (291) tRNA pseudouridine synthase B
M. gilvum PYR-GCKMflv_4028truB1e-11371.03% (290) tRNA pseudouridine synthase B
M. tuberculosis H37RvRv2793ctruB1e-12276.29% (291) tRNA pseudouridine synthase B
M. leprae Br4923MLBr_01546truB1e-12475.25% (303) tRNA pseudouridine synthase B
M. abscessus ATCC 19977MAB_3116ctruB1e-11070.00% (290) tRNA pseudouridine synthase B
M. marinum MMMAR_1917truB1e-16599.00% (301) tRNA pseudouridine synthase B TruB
M. avium 104MAV_3682truB1e-11671.10% (301) tRNA pseudouridine synthase B
M. smegmatis MC2 155MSMEG_2649truB1e-11771.24% (299) tRNA pseudouridine synthase B
M. thermoresistible (build 8)-----
M. vanbaalenii PYR-1Mvan_2329truB1e-11873.45% (290) tRNA pseudouridine synthase B

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_4028|M.gilvum_PYR-GCK          --------MSAEPGLVVVDKPGGMTSHDVVGRCRRLFGTRKVGHAGTLDP
Mvan_2329|M.vanbaalenii_PYR-1       MTEGAHPRNNPAPGLVVVDKPGGMTSHDVVGRCRRLFGTRKVGHAGTLDP
MSMEG_2649|M.smegmatis_MC2_155      --MSGQARSGAEPGLVIVDKPAGMTSHDVVGRCRRLFGTRKVGHAGTLDP
MAB_3116c|M.abscessus_ATCC_199      -----MTDPLSRAGLVIVDKPAGMTSHDVVSRCRRIFSTRKVGHAGTLDP
MAV_3682|M.avium_104                ---------MSPPGLVVVDKPAGMTSHDVVGRCRRIFATRRVGHAGTLDP
MUL_2142|M.ulcerans_Agy99           -MSRQNAGPGFGPGIVVVDKPGAMTSHDVVGRCRRIFGTRRLGHAGTLDP
MMAR_1917|M.marinum_M               -MSRQNAGPGFGPGIVVVDKPGAMTSHDVVGRCRRIFGTRRVGHAGTLDP
MLBr_01546|M.leprae_Br4923          -MSESSTGAGLGPGIVVIDKPSGMTSHDVVARCRRIFCTRRVGHAGTLDP
Mb2816c|M.bovis_AF2122/97           -MSAT------GPGIVVIDKPAGMTSHDVVGRCRRIFATRRVGHAGTLDP
Rv2793c|M.tuberculosis_H37Rv        -MSAT------GPGIVVIDKPAGMTSHDVVGRCRRIFATRRVGHAGTLDP
                                                .*:*::***..*******.****:* **::********

Mflv_4028|M.gilvum_PYR-GCK          MATGVLVIGIERATKILGLLTATDKSYTATLRLGQTTSTEDTEGELLHQV
Mvan_2329|M.vanbaalenii_PYR-1       MATGVLVVGIERATKILGLLTATDKSYAATIRLGQTTSTEDAEGEVLQSV
MSMEG_2649|M.smegmatis_MC2_155      MATGVLVIGIERATKILGLLTATDKSYAATIRLGRTTTTEDAEGEVVEDV
MAB_3116c|M.abscessus_ATCC_199      MATGVLVIGIERATKIMGLLTLTTKSYAATIRFGQSTSTDDAEGEVLQTI
MAV_3682|M.avium_104                MATGVLVLGVERATKILGLLTAAAKSYSATIRLGQATSTDDAEGDVVRSV
MUL_2142|M.ulcerans_Agy99           MATGVLVIGIERATKILGLLIATSKSYAATIRLGQTTSTEDAEGEPLASV
MMAR_1917|M.marinum_M               MATGVLVIGIERATKILGLLTATSKSYAATIRLGQTTSTEDAEGEPLASV
MLBr_01546|M.leprae_Br4923          MATGVLVLGVDRATKILGLLAGASKEYVATIRLGQTTSTEDAEGELLQCV
Mb2816c|M.bovis_AF2122/97           MATGVLVIGIERATKILGLLTAAPKSYAATIRLGQTTSTEDAEGQVLQSV
Rv2793c|M.tuberculosis_H37Rv        MATGVLVIGIERATKILGLLTAAPKSYAATIRLGQTTSTEDAEGQVLQSV
                                    *******:*::*****:***  : *.* **:*:*::*:*:*:**: :  :

Mflv_4028|M.gilvum_PYR-GCK          SAAQVTDEQIERAIAPLRGAIEQVPSAVSAIKIAGKRAYQMVRDGEQVEI
Mvan_2329|M.vanbaalenii_PYR-1       SAAEVTDAQIEAAIAPLRGPIDQIPSAVSAIKIAGKRAYQMVRDGQTVEL
MSMEG_2649|M.smegmatis_MC2_155      PARRVTDEQIHAAVADLRGDIEQVPSAVSAIKVGGQRAYKLAREGQSVEL
MAB_3116c|M.abscessus_ATCC_199      SASHLTEVDIEAAVAGLRGDIAQVPSSVSAIKVDGQRAYKLAREGQSVEL
MAV_3682|M.avium_104                DARHLTSQAIEAAVGGLRGDIHQVPSTVSAIKVAGKRAYKLVREGQAVEL
MUL_2142|M.ulcerans_Agy99           SAEHVAPEAIAAAILDLTGDIRQVPSAVSAIKVDGRRAYQLAREGQTVEL
MMAR_1917|M.marinum_M               SAEHVAPEAIAAAILDLTGDIRQVPSAVSAIKVDGRRAYQLAREGQTVEL
MLBr_01546|M.leprae_Br4923          SARHVTDEAIATAIGRLRGDIKQVPSAVSAIKVDGRRAYRLVREGHVVEL
Mb2816c|M.bovis_AF2122/97           PAKHLTIEAIDAAMERLRGEIRQVPSSVSAIKVGGRRAYRLARQGRSVQL
Rv2793c|M.tuberculosis_H37Rv        PAKHLTIEAIDAAMERLRGEIRQVPSSVSAIKVGGRRAYRLARQGRSVQL
                                     * .::   *  *:  * * * *:**:*****: *:***::.*:*. *::

Mflv_4028|M.gilvum_PYR-GCK          PARPVRIDRFEVLAVRRNG-----DVVDVDVVVDCSSGTYIRALARDVGA
Mvan_2329|M.vanbaalenii_PYR-1       AARPVRIDRFEVLEVRRDG-----ELVDVDVAVDCSSGTYIRALARDVGA
MSMEG_2649|M.smegmatis_MC2_155      AARPVRIDRFDVLDIRRPDDF--PDFVDVDVEVDCSSGTYIRALARDVGA
MAB_3116c|M.abscessus_ATCC_199      AARPVRISRFDVLAVRGSGE----DLIDVDVEIDCSSGTYIRALARDAGA
MAV_3682|M.avium_104                PARPVRIDRFEVRDLRAAG-----ECVDVDVEVDCSSGTYVRALARDLGA
MUL_2142|M.ulcerans_Agy99           AARPVRIDRFELMDLRRG-----ADVIDIDVEVDCSSGTYIRALARDLGA
MMAR_1917|M.marinum_M               AARPVRIDRFELMDLRRG-----ADVIDIDVEVDCSSGTYIRALARDLGA
MLBr_01546|M.leprae_Br4923          QARPVRIDRFEVLAVRPGPEVGLADVIDLDVEVECSSGTYIRALARDLGD
Mb2816c|M.bovis_AF2122/97           EARPIRIDRFELLAARRR-----DQLIDIDVEIDCSSGTYIRALARDLGD
Rv2793c|M.tuberculosis_H37Rv        EARPIRIDRFELLAARRR-----DQLIDIDVEIDCSSGTYIRALARDLGD
                                     ***:**.**::   *        : :*:** ::******:****** * 

Mflv_4028|M.gilvum_PYR-GCK          ALGVGGHLTALRRTRVGGFGLDQARTLEQLADAAELSYSLDEACLHAFPR
Mvan_2329|M.vanbaalenii_PYR-1       ALGVGGHLTALRRTRVGGFGLEQARTLDELAEAPRLSYSLDEACLRAFAR
MSMEG_2649|M.smegmatis_MC2_155      ALGVGGHLTVLRRTRVGRYGLDEAHTLDELAEHPQLSYSLDTACLVGFPR
MAB_3116c|M.abscessus_ATCC_199      ALGVGGHLTALRRTRVGDFGLDRARTLEELADGATLTLDLDSACRQGFPR
MAV_3682|M.avium_104                ALGVGGHLTALRRTRVGRFGLEQAYGLDELAECPRLSYSLDEACLLIFGR
MUL_2142|M.ulcerans_Agy99           ALDVGGHLTSLRRTRVSHFDLSQAASLDELAERPALSLTLDQACLLMFPR
MMAR_1917|M.marinum_M               ALDVGGHLTSLRRTRVGHFDLSQAASLDELAERPALSLTLDQACLLMFPR
MLBr_01546|M.leprae_Br4923          AFGVGGHLTSLRRTRVGRFELDQAWSLEDLAELPRLSRTLDETCLLMFPR
Mb2816c|M.bovis_AF2122/97           ALGVGGHVTALRRTRVGRFELDQARSLDDLAERPALSLSLDEACLLMFAR
Rv2793c|M.tuberculosis_H37Rv        ALGVGGHVTALRRTRVGRFELDQARSLDDLAERPALSLSLDEACLLMFAR
                                    *:.****:* ******. : *..*  *::**: . *:  ** :*   * *

Mflv_4028|M.gilvum_PYR-GCK          RELTDAEVVDAGHG-----------RSLAPAGIDGVYAATAPDGRVMALL
Mvan_2329|M.vanbaalenii_PYR-1       RDITEAEAESASHG-----------RALPVAGIDGVYAATAPDGRVIALL
MSMEG_2649|M.smegmatis_MC2_155      RDLSAEETEDTRHG-----------RPLRPAGIDGVYAATAPDGRVIALL
MAB_3116c|M.abscessus_ATCC_199      RDLDAAEVDAVRNG-----------RPLAPAGIEGTYAAVDADDRVIALL
MAV_3682|M.avium_104                RDLSADEAEAAGNGRALAAAAAGNGRALAAAGIDGVYAACAPDGRVIALL
MUL_2142|M.ulcerans_Agy99           RDLTVDESQSVGNG-----------RPLEPAGIDGIYAASDADGRVIALL
MMAR_1917|M.marinum_M               RDLTVDESQSVGNG-----------RPLEPAGIDGIYAASDADGRVIALL
MLBr_01546|M.leprae_Br4923          RDLTVSEVEATSNG-----------RPISSAGIDGIYAASDADGRVIALL
Mb2816c|M.bovis_AF2122/97           RDLTAAEASAAANG-----------RSLPAVGIDGVYAACDADGRVIALL
Rv2793c|M.tuberculosis_H37Rv        RDLTAAEASAAANG-----------RSLPAVGIDGVYAACDADGRVIALL
                                    *::   *   . :*           *.:  .**:* ***  .*.**:***

Mflv_4028|M.gilvum_PYR-GCK          EDAGPRTRSVVVIRPATL--------------
Mvan_2329|M.vanbaalenii_PYR-1       SDEGDRTRSVVVLRPATL--------------
MSMEG_2649|M.smegmatis_MC2_155      QDGAGRTRNVVVLRPATL--------------
MAB_3116c|M.abscessus_ATCC_199      ADKGSRTTSVVVLRPANL--------------
MAV_3682|M.avium_104                RDEGARTRSVVVIRPATMQDGTS---------
MUL_2142|M.ulcerans_Agy99           RDEGRRTKSVVVIRPATM--------------
MMAR_1917|M.marinum_M               RDEGRRTKSVVVIRPATM--------------
MLBr_01546|M.leprae_Br4923          RDEGPRTKSVVVLHPVFVRVSIGRGIVGVIEA
Mb2816c|M.bovis_AF2122/97           RDEGSRTRSVAVLRPATMHPG-----------
Rv2793c|M.tuberculosis_H37Rv        RDEGSRTRSVAVLRPATMHPG-----------
                                     * . ** .*.*::*. :