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M. tuberculosis H37Rv Rv2693c (-)

annotation: PROBABLE CONSERVED INTEGRAL MEMBRANE ALANINE AND LEUCINE RICH PROTEIN
coordinates: 3010697 - 3011368
length: 223

NANRTSAQRLLAQAGGVSGLVYSSLPVVTFVVASSAAGLLPAIGFALSMAGLILLWRLLRRESARPVVAG
FCGVAVCALIAYLVGQSKGYFLLGIWMSLLWAVVFTLSILIRRPIVGYLWSWLSGRDRAWRDVSRAVFAF
DVATLGWTLVFAARFIVQRHLYDADKTGWLGVARIGMGWPLTALAALATYAAIKAAQRAILASHDAAAVG
GAAEFDADAGRE*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv2693c--100% (223)PROBABLE CONSERVED INTEGRAL MEMBRANE ALANINE AND LEUCINE RICH PROTEIN

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2712c-1e-124100.00% (223) integral membrane alanine and leucine rich protein
M. gilvum PYR-GCKMflv_3929-6e-7665.37% (205) hypothetical protein Mflv_3929
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_2996c-4e-6054.87% (195) hypothetical protein MAB_2996c
M. marinum MMMAR_2021-2e-9376.68% (223) integral membrane alanine and leucine rich protein
M. avium 104MAV_3584-5e-8469.81% (212) hypothetical protein MAV_3584
M. smegmatis MC2 155MSMEG_2770-2e-7461.75% (217) integral membrane alanine and leucine rich protein
M. thermoresistible (build 8)TH_2214-3e-7767.15% (207) PROBABLE CONSERVED INTEGRAL MEMBRANE ALANINE AND LEUCINE RICH
M. ulcerans Agy99MUL_3331-3e-9376.23% (223) integral membrane alanine and leucine rich protein
M. vanbaalenii PYR-1Mvan_2471-3e-7870.68% (191) hypothetical protein Mvan_2471

CLUSTAL 2.0.9 multiple sequence alignment


Rv2693c|M.tuberculosis_H37Rv        --------------------------------MNANRTSAQRLLAQAGGV
Mb2712c|M.bovis_AF2122/97           --------------------------------MNANRTSAQRLLAQAGGV
MMAR_2021|M.marinum_M               --------------------------------MSANRVSAESLLAQAGGV
MUL_3331|M.ulcerans_Agy99           --------------------------------MSANRVSAESLLAQVGGV
MAV_3584|M.avium_104                --------------------------------MTANRINPERLLAQAGGV
Mflv_3929|M.gilvum_PYR-GCK          ----------------------------------------------MGGI
Mvan_2471|M.vanbaalenii_PYR-1       ----------------MSDPGT-----DPGKQQTSPARG-AAVLEQMGGI
MSMEG_2770|M.smegmatis_MC2_155      ----------------MTQADNSPLPESAGEAEVPRARGGRAVLEQMGGI
TH_2214|M.thermoresistible__bu      ------------VNPAADESETRTGDQPPEKATDERSVGAHTMLEQMGGF
MAB_2996c|M.abscessus_ATCC_199      MPETPSHEPDGSGGLDAHEGPHLKISVPGTKPEEPGSSPLHEMWHQAGGW
                                                                                   ** 

Rv2693c|M.tuberculosis_H37Rv        SGLVYSSLPVVTFVVASSAAGLLPAIGFALSMAGLILLWRLLRRESARPV
Mb2712c|M.bovis_AF2122/97           SGLVYSSLPVVTFVVASSAAGLLPAIGFALSMAGLILLWRLLRRESARPV
MMAR_2021|M.marinum_M               SGLVYSSVPVVIFVAVSSIGGLLPAIGSALAAAGLVLLLRLIRRESTQPA
MUL_3331|M.ulcerans_Agy99           SGLVYSSVPVVIFVAVSSIGGLLPAIGSALAAAGLVLLLRLIRRESTQPA
MAV_3584|M.avium_104                SGVIYSSLPVVVFVIASSVSGLVAAIAAALGVAALVLLWRLVRRDSPQPA
Mflv_3929|M.gilvum_PYR-GCK          SGLIYSSLPVVVFVPVSSAFGLLPAIAAALGVATLILIWRLVRRETAQPA
Mvan_2471|M.vanbaalenii_PYR-1       SGLIYSSLPVVVFVPISSAFGLIPAIGAALGVATLILIWRLARKESAQPA
MSMEG_2770|M.smegmatis_MC2_155      SGLIYSSLPVVVFVPVSSLFGLTAAIASALAVATLILIWRLIRRDSVQPA
TH_2214|M.thermoresistible__bu      SGLIYSSLPVVAFVPISNMFGLTSAIVAALGTAAAILVWRLIRRESAQPA
MAB_2996c|M.abscessus_ATCC_199      QGIVYSSIPVIVFVVAVSVSSLIPAIISALVAATLVLIWRLVRRESVQPA
                                    .*::***:**: **   .  .* .**  **  *  :*: ** *::: :*.

Rv2693c|M.tuberculosis_H37Rv        VAGFCGVAVCALIAYLVGQSKGYFLLGIWMSLLWAVVFTLSILIRRPIVG
Mb2712c|M.bovis_AF2122/97           VAGFCGVAVCALIAYLVGQSKGYFLLGIWMSLLWAVVFTLSILIRRPIVG
MMAR_2021|M.marinum_M               VSGFFGVAGCALVAYLVGQSKGYFLLGIWMSLLWAVVFALSIVVRRPVVG
MUL_3331|M.ulcerans_Agy99           VSGFFGVAGCALVAYLVGQSKGYFLLGIWMSLLWAVVFALSIVVRRPVVG
MAV_3584|M.avium_104                ISGFFGVALCALIAYVVGESKGYFLLGIWMSLLWAVVVAASVLIRRPLVG
Mflv_3929|M.gilvum_PYR-GCK          ISGFFAVGISALIAYLVGASKGYFLLGIWMSLFWAVVFALSVVIRRPVVG
Mvan_2471|M.vanbaalenii_PYR-1       ISGFFAVGISALIAYLVGASKGYFLLGIWMSLFWAVVFTLSIVIRRPVVG
MSMEG_2770|M.smegmatis_MC2_155      ISGFFAVGVSALIAYMVGESKGYFLLGIWSSLIYAVVFGISVLIRRPVVG
TH_2214|M.thermoresistible__bu      ISGFFGVGVCVLIAYLMGESKGYFLLGIWMSLLWAAVFGVSVLIRRPVVG
MAB_2996c|M.abscessus_ATCC_199      VSGFISVGISALIAYLLGEAKGYFLIGIWANFFWGTVFLVSVIIRRPIVG
                                    ::** .*. ..*:**::* :*****:*** .:::..*.  *:::***:**

Rv2693c|M.tuberculosis_H37Rv        YLWSWLSGRDRAWRDVSRAVFAFDVATLGWTLVFAARFIVQRHLYDADKT
Mb2712c|M.bovis_AF2122/97           YLWSWLSGRDRAWRDVSRAVFAFDVATLGWTLVFAARFIVQRHLYDADKT
MMAR_2021|M.marinum_M               FLWSWTSGRDQGWREVPRAVYAFDVATLGWTLVFAARFIVQRLLYDADKT
MUL_3331|M.ulcerans_Agy99           FLWSWTSGRDQGWREVPRAVYAFDVATLGWTLVFAARFIVQRLLYDADKT
MAV_3584|M.avium_104                YAWSWAGGRGDGWRSVPRAVYAFDVASLCWVLVFAARFVVQGLLYDADRT
Mflv_3929|M.gilvum_PYR-GCK          YIWGWVNTHDRRWREVRRAVLAFDLATLVWVAVFTSRFVVQHHLYDADQT
Mvan_2471|M.vanbaalenii_PYR-1       YIWAWVHANDRRWREARRAVLAFDAATLVWVAVFTSRFVVQHHLYDADQT
MSMEG_2770|M.smegmatis_MC2_155      YIWGWVHTDDAGWRDVRKAVRAFDIATLTWVAVFGSRFVVQNHLYDADET
TH_2214|M.thermoresistible__bu      YLWGWLSGHGAHWRGVRRAVLAFDIATLTWVLVFSSRFLVQRYLYDADET
MAB_2996c|M.abscessus_ATCC_199      YAYSWATGGDMSWRGNRRIVTAFDIATVSWIVLFAVRFVVQEWLYLAGNT
                                    : :.*    .  **   : * *** *:: *  :*  **:**  ** *..*

Rv2693c|M.tuberculosis_H37Rv        GWLGVARIGMGWPLTALAALATYAAIKAAQRAILASHDAAAVGGAAEFDA
Mb2712c|M.bovis_AF2122/97           GWLGVARIGMGWPLTALAALATYAAIKAAQRAILASHDAAAVGGAAEFDA
MMAR_2021|M.marinum_M               GWLGVARIGMGWPLTAVAALATYAAIKAARRAMPAADEPEAA-EVAAVDT
MUL_3331|M.ulcerans_Agy99           GWLGVARIGMGWPLTAVAALATYAAIKAARRAMPAADEPEAA-EVAAVDT
MAV_3584|M.avium_104                GWLAAARIGMGWPLTVLAALATYAAIKSAQRAIAAVELASGAAGE-----
Mflv_3929|M.gilvum_PYR-GCK          GWLGVARIAMGWPLTAVAALVTYLAIRRAQRYVREAGLGDTDTDAR---S
Mvan_2471|M.vanbaalenii_PYR-1       GWLGVARIAMGWPLTAVAALVTYLAIRAAQRALHERGLNEPADTAHGDDV
MSMEG_2770|M.smegmatis_MC2_155      TWLGVARIAMGWPLTAVAALVTYLAIRSAQRAVREHQAARHIDAATGSGS
TH_2214|M.thermoresistible__bu      GWLGVARIAMGWPLTAVAALVTYLAIRTAQRALEHHRAAGGAPASG----
MAB_2996c|M.abscessus_ATCC_199      AWLGGAKIAMGWPLTAVGALVTLLVIRYVRRHTDQAEDRAPESEPPA---
                                     **. *:*.******.:.**.*  .*: .:*                   

Rv2693c|M.tuberculosis_H37Rv        DAGRE--------
Mb2712c|M.bovis_AF2122/97           DAGRE--------
MMAR_2021|M.marinum_M               EACREL-------
MUL_3331|M.ulcerans_Agy99           EACREL-------
MAV_3584|M.avium_104                -------------
Mflv_3929|M.gilvum_PYR-GCK          VSAAED-------
Mvan_2471|M.vanbaalenii_PYR-1       HDAAQEPT-----
MSMEG_2770|M.smegmatis_MC2_155      EPAAESGAEPHAG
TH_2214|M.thermoresistible__bu      -------------
MAB_2996c|M.abscessus_ATCC_199      -------------