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VSDPGTDPGKQQTSPARGAAVLEQMGGISGLIYSSLPVVVFVPISSAFGLIPAIGAALGVATLILIWRLA RKESAQPAISGFFAVGISALIAYLVGASKGYFLLGIWMSLFWAVVFTLSIVIRRPVVGYIWAWVHANDRR WREARRAVLAFDAATLVWVAVFTSRFVVQHHLYDADQTGWLGVARIAMGWPLTAVAALVTYLAIRAAQRA LHERGLNEPADTAHGDDVHDAAQEPT
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_2471 | - | - | 100% (236) | hypothetical protein Mvan_2471 |
| M. vanbaalenii PYR-1 | Mvan_2125 | - | 5e-48 | 47.12% (191) | putative integral membrane alanine and leucine rich protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2712c | - | 2e-78 | 70.68% (191) | integral membrane alanine and leucine rich protein |
| M. gilvum PYR-GCK | Mflv_3929 | - | 6e-98 | 89.18% (194) | hypothetical protein Mflv_3929 |
| M. tuberculosis H37Rv | Rv2693c | - | 2e-78 | 70.68% (191) | integral membrane alanine and leucine rich protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2996c | - | 2e-65 | 57.42% (209) | hypothetical protein MAB_2996c |
| M. marinum M | MMAR_2021 | - | 2e-75 | 65.22% (207) | integral membrane alanine and leucine rich protein |
| M. avium 104 | MAV_3584 | - | 4e-71 | 66.49% (191) | hypothetical protein MAV_3584 |
| M. smegmatis MC2 155 | MSMEG_2770 | - | 3e-89 | 72.57% (226) | integral membrane alanine and leucine rich protein |
| M. thermoresistible (build 8) | TH_2214 | - | 3e-82 | 72.25% (209) | PROBABLE CONSERVED INTEGRAL MEMBRANE ALANINE AND LEUCINE RICH |
| M. ulcerans Agy99 | MUL_3331 | - | 7e-76 | 65.22% (207) | integral membrane alanine and leucine rich protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2712c|M.bovis_AF2122/97 --------------------------------MNANRTSAQRLLAQAGGV
Rv2693c|M.tuberculosis_H37Rv --------------------------------MNANRTSAQRLLAQAGGV
MMAR_2021|M.marinum_M --------------------------------MSANRVSAESLLAQAGGV
MUL_3331|M.ulcerans_Agy99 --------------------------------MSANRVSAESLLAQVGGV
MAV_3584|M.avium_104 --------------------------------MTANRINPERLLAQAGGV
Mvan_2471|M.vanbaalenii_PYR-1 ----------------MSDPGT-----DPGKQQTSPARG-AAVLEQMGGI
Mflv_3929|M.gilvum_PYR-GCK ----------------------------------------------MGGI
MSMEG_2770|M.smegmatis_MC2_155 ----------------MTQADNSPLPESAGEAEVPRARGGRAVLEQMGGI
TH_2214|M.thermoresistible__bu ------------VNPAADESETRTGDQPPEKATDERSVGAHTMLEQMGGF
MAB_2996c|M.abscessus_ATCC_199 MPETPSHEPDGSGGLDAHEGPHLKISVPGTKPEEPGSSPLHEMWHQAGGW
**
Mb2712c|M.bovis_AF2122/97 SGLVYSSLPVVTFVVASSAAGLLPAIGFALSMAGLILLWRLLRRESARPV
Rv2693c|M.tuberculosis_H37Rv SGLVYSSLPVVTFVVASSAAGLLPAIGFALSMAGLILLWRLLRRESARPV
MMAR_2021|M.marinum_M SGLVYSSVPVVIFVAVSSIGGLLPAIGSALAAAGLVLLLRLIRRESTQPA
MUL_3331|M.ulcerans_Agy99 SGLVYSSVPVVIFVAVSSIGGLLPAIGSALAAAGLVLLLRLIRRESTQPA
MAV_3584|M.avium_104 SGVIYSSLPVVVFVIASSVSGLVAAIAAALGVAALVLLWRLVRRDSPQPA
Mvan_2471|M.vanbaalenii_PYR-1 SGLIYSSLPVVVFVPISSAFGLIPAIGAALGVATLILIWRLARKESAQPA
Mflv_3929|M.gilvum_PYR-GCK SGLIYSSLPVVVFVPVSSAFGLLPAIAAALGVATLILIWRLVRRETAQPA
MSMEG_2770|M.smegmatis_MC2_155 SGLIYSSLPVVVFVPVSSLFGLTAAIASALAVATLILIWRLIRRDSVQPA
TH_2214|M.thermoresistible__bu SGLIYSSLPVVAFVPISNMFGLTSAIVAALGTAAAILVWRLIRRESAQPA
MAB_2996c|M.abscessus_ATCC_199 QGIVYSSIPVIVFVVAVSVSSLIPAIISALVAATLVLIWRLVRRESVQPA
.*::***:**: ** . .* .** ** * :*: ** *::: :*.
Mb2712c|M.bovis_AF2122/97 VAGFCGVAVCALIAYLVGQSKGYFLLGIWMSLLWAVVFTLSILIRRPIVG
Rv2693c|M.tuberculosis_H37Rv VAGFCGVAVCALIAYLVGQSKGYFLLGIWMSLLWAVVFTLSILIRRPIVG
MMAR_2021|M.marinum_M VSGFFGVAGCALVAYLVGQSKGYFLLGIWMSLLWAVVFALSIVVRRPVVG
MUL_3331|M.ulcerans_Agy99 VSGFFGVAGCALVAYLVGQSKGYFLLGIWMSLLWAVVFALSIVVRRPVVG
MAV_3584|M.avium_104 ISGFFGVALCALIAYVVGESKGYFLLGIWMSLLWAVVVAASVLIRRPLVG
Mvan_2471|M.vanbaalenii_PYR-1 ISGFFAVGISALIAYLVGASKGYFLLGIWMSLFWAVVFTLSIVIRRPVVG
Mflv_3929|M.gilvum_PYR-GCK ISGFFAVGISALIAYLVGASKGYFLLGIWMSLFWAVVFALSVVIRRPVVG
MSMEG_2770|M.smegmatis_MC2_155 ISGFFAVGVSALIAYMVGESKGYFLLGIWSSLIYAVVFGISVLIRRPVVG
TH_2214|M.thermoresistible__bu ISGFFGVGVCVLIAYLMGESKGYFLLGIWMSLLWAAVFGVSVLIRRPVVG
MAB_2996c|M.abscessus_ATCC_199 VSGFISVGISALIAYLLGEAKGYFLIGIWANFFWGTVFLVSVIIRRPIVG
::** .*. ..*:**::* :*****:*** .:::..*. *:::***:**
Mb2712c|M.bovis_AF2122/97 YLWSWLSGRDRAWRDVSRAVFAFDVATLGWTLVFAARFIVQRHLYDADKT
Rv2693c|M.tuberculosis_H37Rv YLWSWLSGRDRAWRDVSRAVFAFDVATLGWTLVFAARFIVQRHLYDADKT
MMAR_2021|M.marinum_M FLWSWTSGRDQGWREVPRAVYAFDVATLGWTLVFAARFIVQRLLYDADKT
MUL_3331|M.ulcerans_Agy99 FLWSWTSGRDQGWREVPRAVYAFDVATLGWTLVFAARFIVQRLLYDADKT
MAV_3584|M.avium_104 YAWSWAGGRGDGWRSVPRAVYAFDVASLCWVLVFAARFVVQGLLYDADRT
Mvan_2471|M.vanbaalenii_PYR-1 YIWAWVHANDRRWREARRAVLAFDAATLVWVAVFTSRFVVQHHLYDADQT
Mflv_3929|M.gilvum_PYR-GCK YIWGWVNTHDRRWREVRRAVLAFDLATLVWVAVFTSRFVVQHHLYDADQT
MSMEG_2770|M.smegmatis_MC2_155 YIWGWVHTDDAGWRDVRKAVRAFDIATLTWVAVFGSRFVVQNHLYDADET
TH_2214|M.thermoresistible__bu YLWGWLSGHGAHWRGVRRAVLAFDIATLTWVLVFSSRFLVQRYLYDADET
MAB_2996c|M.abscessus_ATCC_199 YAYSWATGGDMSWRGNRRIVTAFDIATVSWIVLFAVRFVVQEWLYLAGNT
: :.* . ** : * *** *:: * :* **:** ** *..*
Mb2712c|M.bovis_AF2122/97 GWLGVARIGMGWPLTALAALATYAAIKAAQRAILASHDAAAVGGAAEFDA
Rv2693c|M.tuberculosis_H37Rv GWLGVARIGMGWPLTALAALATYAAIKAAQRAILASHDAAAVGGAAEFDA
MMAR_2021|M.marinum_M GWLGVARIGMGWPLTAVAALATYAAIKAARRAMPAADEPEAA-EVAAVDT
MUL_3331|M.ulcerans_Agy99 GWLGVARIGMGWPLTAVAALATYAAIKAARRAMPAADEPEAA-EVAAVDT
MAV_3584|M.avium_104 GWLAAARIGMGWPLTVLAALATYAAIKSAQRAIAAVELASGAAGE-----
Mvan_2471|M.vanbaalenii_PYR-1 GWLGVARIAMGWPLTAVAALVTYLAIRAAQRALHERGLNEPADTAHGDDV
Mflv_3929|M.gilvum_PYR-GCK GWLGVARIAMGWPLTAVAALVTYLAIRRAQRYVREAGLGDTDTDAR---S
MSMEG_2770|M.smegmatis_MC2_155 TWLGVARIAMGWPLTAVAALVTYLAIRSAQRAVREHQAARHIDAATGSGS
TH_2214|M.thermoresistible__bu GWLGVARIAMGWPLTAVAALVTYLAIRTAQRALEHHRAAGGAPASG----
MAB_2996c|M.abscessus_ATCC_199 AWLGGAKIAMGWPLTAVGALVTLLVIRYVRRHTDQAEDRAPESEPPA---
**. *:*.******.:.**.* .*: .:*
Mb2712c|M.bovis_AF2122/97 DAGRE--------
Rv2693c|M.tuberculosis_H37Rv DAGRE--------
MMAR_2021|M.marinum_M EACREL-------
MUL_3331|M.ulcerans_Agy99 EACREL-------
MAV_3584|M.avium_104 -------------
Mvan_2471|M.vanbaalenii_PYR-1 HDAAQEPT-----
Mflv_3929|M.gilvum_PYR-GCK VSAAED-------
MSMEG_2770|M.smegmatis_MC2_155 EPAAESGAEPHAG
TH_2214|M.thermoresistible__bu -------------
MAB_2996c|M.abscessus_ATCC_199 -------------