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VDPVRRQLYQFVCSQSMPVSRDQAADAVGIPRHQAKFHLDRLTAEGLLDTEYARLTGRSGPGAGRTAKLY RRAGRDIALSLPQREYELAGRLMAAAIVLSATTGEPTVEVLNRIAHDYGQAMGAAATTRPPADPAAALEL TLDVLRKYGYEPRRPAGPGDDEVELVNCPFHALAREQTELACNMNHALITGVADALAPHSPAVRLAPGPA RCCVVLKRCSAHDPE
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv2618 | - | - | 100% (225) | hypothetical protein Rv2618 |
| M. tuberculosis H37Rv | Rv2621c | - | 1e-11 | 26.18% (191) | transcriptional regulatory protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2651 | - | 1e-129 | 100.00% (225) | hypothetical protein Mb2651 |
| M. gilvum PYR-GCK | Mflv_3487 | - | 9e-08 | 28.92% (204) | putative transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_2081 | - | 2e-07 | 22.86% (210) | transcriptional regulator |
| M. avium 104 | MAV_3499 | - | 4e-12 | 29.13% (206) | hypothetical protein MAV_3499 |
| M. smegmatis MC2 155 | MSMEG_1125 | - | 3e-10 | 27.18% (206) | regulatory protein, ArsR |
| M. thermoresistible (build 8) | TH_4089 | - | 3e-42 | 43.64% (220) | PUTATIVE putative DNA ligase |
| M. ulcerans Agy99 | MUL_3263 | - | 2e-07 | 22.86% (210) | transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_5848 | - | 1e-11 | 25.98% (204) | putative transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_2081|M.marinum_M --MGE----GR--IARMGGEPAGRRRAVLRVLRALGHPLSIVAIAEHLGV
MUL_3263|M.ulcerans_Agy99 --MGE----GR--IARMGGEPAGRRRAVLRVLRALGHPLSIVAIAEHLGV
MAV_3499|M.avium_104 --MGDPLTKSRKLLAPSAGESAGRRRAVLRLLRASPEPMSIAGIADVLGV
Mvan_5848|M.vanbaalenii_PYR-1 ------------MSAASPGEPPGRRRDVLRTLKAASGPMSIGAIADALDI
MSMEG_1125|M.smegmatis_MC2_155 ------------MDTDTSLPPRGRRDAILQVLRASPQPRAIAGIADELGV
Mflv_3487|M.gilvum_PYR-GCK MNKEGLVLGPHPTRTVAGYPPLSRQRLCVLDYVRTHAPVRITAVAAALDL
Rv2618|M.tuberculosis_H37Rv --------------------MDPVRRQLYQFVCSQSMPVSRDQAADAVGI
Mb2651|M.bovis_AF2122/97 --------------------MDPVRRQLYQFVCSQSMPVSRDQAADAVGI
TH_4089|M.thermoresistible__bu --MAIGGSHDSVAVAALSSLDDPLRRQMYEFVADADGPVSREEAAAAAGV
: * * .:
MMAR_2081|M.marinum_M HPNTVRFHLDGLVDDGQVERVQPSRRGP-----GRPPLMFRAVQQMDRG-
MUL_3263|M.ulcerans_Agy99 HPNTVRFHLDGLVDDGQVERVQPSRRGP-----GRPPLMFRAVQQMDRG-
MAV_3499|M.avium_104 HPNTVRFHLDSLVADGQVEHVELDRKGP-----GRPPLMFRAVRQMDRG-
Mvan_5848|M.vanbaalenii_PYR-1 HPNTVRFHLDRLVSQGQVERIEPDRRRP-----GRPPQMFRAMPQMDRA-
MSMEG_1125|M.smegmatis_MC2_155 HPNTVRFHLEALARAGRVEQVVGEAFGR-----GRPPVLYRASRRMDPS-
Mflv_3487|M.gilvum_PYR-GCK HPNTVREHLDALTGHGLAERVTETPSKR-----GRPAALYRPSAADPAI-
Rv2618|M.tuberculosis_H37Rv PRHQAKFHLDRLTAEGLLDTEYARLTGRSGPGAGRTAKLYRRAGRDIALS
Mb2651|M.bovis_AF2122/97 PRHQAKFHLDRLTAEGLLDTEYARLTGRSGPGAGRTAKLYRRAGRDIALS
TH_4089|M.thermoresistible__bu GRTLAAYHLDKLAEAGLLTVSYQRPPGRSGPGAGRPAKVYTPSAREVSVS
. **: *. * **.. ::
MMAR_2081|M.marinum_M -GARHYQLLAEILSNGLAAESD--SVDKALAAGRAWGERLQA-----PTT
MUL_3263|M.ulcerans_Agy99 -GARHYQLLAEILSNGLAAESD--SVDKALAAGRAWGERLQA-----PTT
MAV_3499|M.avium_104 -GTRHYRLLAEILAKAFAAETD--PAPKALAAGRAWGQQLDAERRRLPRD
Mvan_5848|M.vanbaalenii_PYR-1 -GPRHYRLLAEMLAMSLAADGD--PPTRAQAGGRAWGRELNVRAP--RRK
MSMEG_1125|M.smegmatis_MC2_155 -GPTNYRLLASILTGYVARHPD--AAAVAADLGRSTSPGLVTTA---PHG
Mflv_3487|M.gilvum_PYR-GCK -PAQDYAGLATALAGHIARTSTQ-PERDARAAGASWGHELCD-------D
Rv2618|M.tuberculosis_H37Rv LPQREYELAGRLMAAAIVLSATTGEPTVEVLNRIAHDYGQAMGAAATTRP
Mb2651|M.bovis_AF2122/97 LPQREYELAGRLMAAAIVLSATTGEPTVEVLNRIAHDYGQAMGAAATTRP
TH_4089|M.thermoresistible__bu VPPRAYEFLARL----IVEAAERDDHVRTTVNETAYDAGRRVGADAAG--
* . .. : .
MMAR_2081|M.marinum_M AHSAEKSIDHLVGVLDGLGFAPERRVSDGQQQVALRHCPFLELAENRSGV
MUL_3263|M.ulcerans_Agy99 AHSAEKSIDHLVGVLDGLGFAPERRVSDGQQQVALRHCPFLELAENRSGV
MAV_3499|M.avium_104 AAGAEQAIAQLVDVLDELGFAPERRVIDGEQQVGLRHCPFLELAENSSNV
Mvan_5848|M.vanbaalenii_PYR-1 QSGAEEAVDRLVEVLDDVGFVPERLGAGEKQQIGLRHCPFLELAETQSRV
MSMEG_1125|M.smegmatis_MC2_155 PSTRTQAVTELVDLLAELGFEPEPADGRRAREIRLRHCPFQNLAEEHGEV
Mflv_3487|M.gilvum_PYR-GCK TVTTDDPRAAVLTVLARLGFGPDADGPDGS--IALRSCPLLEAARRYPAI
Rv2618|M.tuberculosis_H37Rv PADPAAALELTLDVLRKYGYEPRRPAGPGDDEVELVNCPFHALAREQTEL
Mb2651|M.bovis_AF2122/97 PADPAAALELTLDVLRKYGYEPRRPAGPGDDEVELVNCPFHALAREQTEL
TH_4089|M.thermoresistible__bu --DLIAA-------LRSCGY---RPAVSDDDTVILRNCPFHAVAEDHTEV
. * *: : * **: *. :
MMAR_2081|M.marinum_M VCPIHLGLMRGALESWGAP-VTVERLDPFVEPDLCLAHLSPEGALS----
MUL_3263|M.ulcerans_Agy99 VCPIHLGLMRGALESWGAP-VTVERLDPFVEPDLCLAHLSPEGALS----
MAV_3499|M.avium_104 VCPVHLGLMQGAMESWGAP-VSVDRLDPFVEPDLCLAHLTLQGADR----
Mvan_5848|M.vanbaalenii_PYR-1 VCGIHLGLMQGVLERQGAP-VTVDRLEPFAQPDLCLAHLTLRGRPPQA--
MSMEG_1125|M.smegmatis_MC2_155 TCALHLGLMQGALRDLQAP-VTVDRLEPFVEPDLCVAHLAPR--------
Mflv_3487|M.gilvum_PYR-GCK VCQVHLGIVEGVLERFGAVTDTAPELVAFAEPGACRLFLPDPVVPERNRP
Rv2618|M.tuberculosis_H37Rv ACNMNHALITGVADALAPH-SPAVRLAP--GPARCCVVLKRCSAHDPE--
Mb2651|M.bovis_AF2122/97 ACNMNHALITGVADALAPH-SPAVRLAP--GPARCCVVLKRCSAHDPE--
TH_4089|M.thermoresistible__bu VCGLNLRLIEGIVEGSRDR-TARPRLEP--HPTRCCVVVHRRAASRS---
.* :: :: * . .* . * * :