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CHGGTWAGDYVLNVIATGLSLKARGKRRRQRWVDDGRVLALGESRRSSAISVADVVASLTRDVADFPVPG VEFKDLTPLFADRRGLAAVTEALADRASGADLVAGVDARGFLVAAAVATRLEVGVLAVRKGGKLPRPVLS EEYYRAYGAATLEILAEGIEVAGRRVVIIDDVLATGGTIGATRRLLERGGANVAGAAVVVELAGLSGRAA LAPLPVHSLSRL*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv2584c | apt | - | 100% (223) | adenine phosphoribosyltransferase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2615c | apt | 1e-120 | 99.55% (223) | adenine phosphoribosyltransferase |
| M. gilvum PYR-GCK | Mflv_3813 | - | 2e-56 | 64.88% (168) | adenine phosphoribosyltransferase |
| M. leprae Br4923 | MLBr_02487 | pyrE | 8e-06 | 29.11% (79) | orotate phosphoribosyltransferase |
| M. abscessus ATCC 19977 | MAB_2877c | - | 2e-58 | 67.26% (168) | adenine phosphoribosyltransferase |
| M. marinum M | MMAR_2123 | apt | 6e-62 | 69.41% (170) | adenine phosphoribosyltransferase, Apt |
| M. avium 104 | MAV_3465 | - | 5e-61 | 69.19% (172) | adenine phosphoribosyltransferase |
| M. smegmatis MC2 155 | MSMEG_2964 | - | 4e-59 | 70.83% (168) | adenine phosphoribosyltransferase |
| M. thermoresistible (build 8) | TH_0744 | apt | 2e-57 | 65.50% (171) | ADENINE PHOSPHORIBOSYLTRANSFERASE APT (APRT) (AMP |
| M. ulcerans Agy99 | MUL_1728 | apt | 1e-62 | 70.00% (170) | adenine phosphoribosyltransferase |
| M. vanbaalenii PYR-1 | Mvan_2586 | - | 6e-59 | 68.45% (168) | adenine phosphoribosyltransferase |
CLUSTAL 2.0.9 multiple sequence alignment
Rv2584c|M.tuberculosis_H37Rv MCHGGTWAGDYVLNVIATGLSLKARGKRRRQRWVDDGRVLALGESRRSSA
Mb2615c|M.bovis_AF2122/97 MCHGGTWAGDYVLNVIATGLSLKARGKRRRQRWVDDGRVLALGESRRSSA
MMAR_2123|M.marinum_M -----------MTDLVVTGR----------------------------GS
MUL_1728|M.ulcerans_Agy99 -----------MTDLVVTGR----------------------------GS
MAV_3465|M.avium_104 -----------MTD---AG-----------------------------EA
MAB_2877c|M.abscessus_ATCC_199 MTG----------------------------------------------P
MSMEG_2964|M.smegmatis_MC2_155 MTQHH-------------------------------------------DT
Mflv_3813|M.gilvum_PYR-GCK MSGE--------------------------------------------PG
Mvan_2586|M.vanbaalenii_PYR-1 -------------------------------------------------M
TH_0744|M.thermoresistible__bu MSGAG-------------------------------------------YA
MLBr_02487|M.leprae_Br4923 ------------------------------------------------MA
Rv2584c|M.tuberculosis_H37Rv ISVADVVASLTRDVADFPVPGVEFKDLTPLFADRRGLAAVTEALADRASG
Mb2615c|M.bovis_AF2122/97 ISVADVVASLTRDVADFPVPGVEFKDLTPLFADRRGLAAVTEALADRASG
MMAR_2123|M.marinum_M APVADLISSLTRDVADFPKPGIQFKDLTPLFADREAMAAVIDALADIAAG
MUL_1728|M.ulcerans_Agy99 APVADLISSLTRDVADFPKPGIQFKDLTPLFADREAMAAVIDALADIAAG
MAV_3465|M.avium_104 TPVAELIASLTRQVPDFPKPGIQFKDLTPLFADATAMTAVTGALARHASG
MAB_2877c|M.abscessus_ATCC_199 DEIAELVASLTREVADFPEPGVQFKDLTPLFADADGLSRVTDALAQAASG
MSMEG_2964|M.smegmatis_MC2_155 AEVSRVIATLTREVADFPEPGIQFKDLTPLLADARGLRVVTDALADIASG
Mflv_3813|M.gilvum_PYR-GCK TDIAEVIRSLMREVPDFPEPGVHFKDLTPVLADAYGLAEVSRAIADSARG
Mvan_2586|M.vanbaalenii_PYR-1 TDIADVIRSLMREVPDFPEPGVHFKDLTPVLADARGLAEVSKAIADAARG
TH_0744|M.thermoresistible__bu ADAAALIAAHLREVADFPEPGIQFKDLTPVLADARALTVVTDALAANIGG
MLBr_02487|M.leprae_Br4923 ELDRKELADLVRRLSVVQG-CVTLSSGKQADHYVDLRRATLHHRASALIG
: * :. . : :.. . . * *
Rv2584c|M.tuberculosis_H37Rv ADLVAGVDARGFLVAAAVATRLE-VGVLAVRKGGKLPRPVLSEEYYRAYG
Mb2615c|M.bovis_AF2122/97 ADLVAGVDARGFLVAAAVATRLE-VGVLAVRKGGKLPRPVLSEEYYREYG
MMAR_2123|M.marinum_M TDLVAGIESRGSLVAAALAARLG-TGVLSIRKSGKLPPPVLTEEYDREYG
MUL_1728|M.ulcerans_Agy99 TDLVAGIESRGSLVAAALAARLG-TGVLSIRKSGKLPPPVLTEEYDREYG
MAV_3465|M.avium_104 ADLVAGIDSRGFLVAAAVADRLH-TGVLAIRKGGKLPPPVHAERYDLEYG
MAB_2877c|M.abscessus_ATCC_199 ATLIAGIDARGFLLGAAVAIRLG-VGVLAVRKAGKLPPPVHAQTYQLEYG
MSMEG_2964|M.smegmatis_MC2_155 ADLVAGLDARGFLLGAAVATRLG-TGVLAVRKGGKLPPPVHGATYQLEYG
Mflv_3813|M.gilvum_PYR-GCK ADLVAGVDARGFLLGGAVAVTLG-IGVLAVRKGGKLPPPVLGETYTLEYG
Mvan_2586|M.vanbaalenii_PYR-1 ADLVAGVDARGFLLGGAVAVTLG-IGVLAVRKGGKLPPPVIGATYTLEYG
TH_0744|M.thermoresistible__bu ADLVAGLDARGFLIGAAVAIRLG-TGVLAVRKGGKLPPPVRSESYVLEYG
MLBr_02487|M.leprae_Br4923 RLMRELTKDWNYTVVGGLTLGADPVAIAIIHSPGRPIDAFVVRKYAKTHG
: . . : ..:: .: ::. *: .. * :*
Rv2584c|M.tuberculosis_H37Rv AATLEILAEGIEVAGRRVVIIDDVLATGGTIGATRRLLERGGANVAGAAV
Mb2615c|M.bovis_AF2122/97 AATLEILAEGIEVAGRRVVIIDDVLATGGTIGATRRLLERGGANVAGAAV
MMAR_2123|M.marinum_M AASMEIPADSLELRGRSVMIIDDVLATGGTLGAATRLLKRTGARVTGAAV
MUL_1728|M.ulcerans_Agy99 AASMEIPADSLELRGRSVMIIDDVLATGGTLGAATRLLERTGARVTGAAV
MAV_3465|M.avium_104 SATLEIPADGIDLRGRRIVIIDDVLATGGTLAAAARLLRRTGATVTAAAV
MAB_2877c|M.abscessus_ATCC_199 TAALEIPADGVELAGRRVAIVDDVLATGGTLAATARLLTTAGADVISAGV
MSMEG_2964|M.smegmatis_MC2_155 TATLEIPAEGIDIAGRNVVIIDDVLATGGTLAAAARLLGDCGANVTGAGV
Mflv_3813|M.gilvum_PYR-GCK SATLEVPADGVELAGRSVVVIDDVLATGGTLAAAHQLLTKAGANVTGAVV
Mvan_2586|M.vanbaalenii_PYR-1 TATLEVPAEGIELAGRSVVVIDDVLATGGTLAATHQLLTRAGANVTGAVV
TH_0744|M.thermoresistible__bu TASLEIPAEGIDLTGQRVVIVDDVLATGGTVAAAARLLRSAGATVSGVAV
MLBr_02487|M.leprae_Br4923 ---LQRLIEGSEVSGQRVLVVEDTSTTGASALTAVRAVQDAGGDVVGVAT
:: :. :: *: : :::*. :**.: :: : : *. * .. .
Rv2584c|M.tuberculosis_H37Rv VVELAGLSGRAALAP-------LPVHSLSRL
Mb2615c|M.bovis_AF2122/97 VVELAGLSGRAALAP-------LPVHSLSRL
MMAR_2123|M.marinum_M VVELTALRGREAIAP-------LRVHSLSRA
MUL_1728|M.ulcerans_Agy99 VVELTALRGREAIAP-------LRVHSLSRA
MAV_3465|M.avium_104 VFELGALGGRAALAP-------LPVHRLTCQ
MAB_2877c|M.abscessus_ATCC_199 VLELSDLGGRAAVAP-------LPLTALRAI
MSMEG_2964|M.smegmatis_MC2_155 VLELEALRGREAVAP-------LGVRSLHII
Mflv_3813|M.gilvum_PYR-GCK MMELTALGGRAAVDP-------LEVTSLYSV
Mvan_2586|M.vanbaalenii_PYR-1 MMELAALGGRAALEP-------LEVTSLYTA
TH_0744|M.thermoresistible__bu VLELGGLGGRAALEP-------LPVSSLYTT
MLBr_02487|M.leprae_Br4923 VVDRGTGAAEAIKAEGLLYRSVLGLADLGLG
:.: .. * : *