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SGEPGTDIAEVIRSLMREVPDFPEPGVHFKDLTPVLADAYGLAEVSRAIADSARGADLVAGVDARGFLLG GAVAVTLGIGVLAVRKGGKLPPPVLGETYTLEYGSATLEVPADGVELAGRSVVVIDDVLATGGTLAAAHQ LLTKAGANVTGAVVMMELTALGGRAAVDPLEVTSLYSV*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_3813 | - | - | 100% (179) | adenine phosphoribosyltransferase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2615c | apt | 3e-57 | 65.48% (168) | adenine phosphoribosyltransferase |
| M. tuberculosis H37Rv | Rv2584c | apt | 1e-56 | 64.88% (168) | adenine phosphoribosyltransferase |
| M. leprae Br4923 | MLBr_00248 | prsA | 5e-05 | 32.69% (104) | ribose-phosphate pyrophosphokinase |
| M. abscessus ATCC 19977 | MAB_2877c | - | 4e-62 | 67.44% (172) | adenine phosphoribosyltransferase |
| M. marinum M | MMAR_2123 | apt | 6e-55 | 59.09% (176) | adenine phosphoribosyltransferase, Apt |
| M. avium 104 | MAV_3465 | - | 3e-58 | 65.29% (170) | adenine phosphoribosyltransferase |
| M. smegmatis MC2 155 | MSMEG_2964 | - | 1e-62 | 69.77% (172) | adenine phosphoribosyltransferase |
| M. thermoresistible (build 8) | TH_0744 | apt | 3e-60 | 64.91% (171) | ADENINE PHOSPHORIBOSYLTRANSFERASE APT (APRT) (AMP |
| M. ulcerans Agy99 | MUL_1728 | apt | 4e-55 | 59.09% (176) | adenine phosphoribosyltransferase |
| M. vanbaalenii PYR-1 | Mvan_2586 | - | 2e-85 | 91.28% (172) | adenine phosphoribosyltransferase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3813|M.gilvum_PYR-GCK -------------------------------MSGEP--------------
Mvan_2586|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_2964|M.smegmatis_MC2_155 -------------------------------------MTQHH--------
TH_0744|M.thermoresistible__bu -------------------------------------MSGAG--------
MAB_2877c|M.abscessus_ATCC_199 -------------------------------------MTGP---------
Mb2615c|M.bovis_AF2122/97 -------------------------MCHGGTWAGD-YVLNVIATGLSLKA
Rv2584c|M.tuberculosis_H37Rv -------------------------MCHGGTWAGD-YVLNVIATGLSLKA
MMAR_2123|M.marinum_M -------------------------------------MTDLVVTGR----
MUL_1728|M.ulcerans_Agy99 -------------------------------------MTDLVVTGR----
MAV_3465|M.avium_104 -------------------------------------MTD---AG-----
MLBr_00248|M.leprae_Br4923 MLSHDWTDNRKNLMLFSGRAHPELAEQVAKELDMHVTTQDAREFANGEIF
Mflv_3813|M.gilvum_PYR-GCK -------------------------GTDIAEVIRSLMREVPDFPEPGVHF
Mvan_2586|M.vanbaalenii_PYR-1 -------------------------MTDIADVIRSLMREVPDFPEPGVHF
MSMEG_2964|M.smegmatis_MC2_155 ------------------------DTAEVSRVIATLTREVADFPEPGIQF
TH_0744|M.thermoresistible__bu ------------------------YAADAAALIAAHLREVADFPEPGIQF
MAB_2877c|M.abscessus_ATCC_199 --------------------------DEIAELVASLTREVADFPEPGVQF
Mb2615c|M.bovis_AF2122/97 RGKRRRQRWVDDGRVLALGESRRSSAISVADVVASLTRDVADFPVPGVEF
Rv2584c|M.tuberculosis_H37Rv RGKRRRQRWVDDGRVLALGESRRSSAISVADVVASLTRDVADFPVPGVEF
MMAR_2123|M.marinum_M ------------------------GSAPVADLISSLTRDVADFPKPGIQF
MUL_1728|M.ulcerans_Agy99 ------------------------GSAPVADLISSLTRDVADFPKPGIQF
MAV_3465|M.avium_104 ------------------------EATPVAELIASLTRQVPDFPKPGIQF
MLBr_00248|M.leprae_Br4923 VRFHESVRGCDAFVLQSCPAPVNTWLMEQLIMIDALKRGSAKRITAVIPF
:: : * .. . : *
Mflv_3813|M.gilvum_PYR-GCK KDLTPVLADAYGLAEVSRAIAD---SARGADLVAGVDAR-----GFLLGG
Mvan_2586|M.vanbaalenii_PYR-1 KDLTPVLADARGLAEVSKAIAD---AARGADLVAGVDAR-----GFLLGG
MSMEG_2964|M.smegmatis_MC2_155 KDLTPLLADARGLRVVTDALAD---IASGADLVAGLDAR-----GFLLGA
TH_0744|M.thermoresistible__bu KDLTPVLADARALTVVTDALAA---NIGGADLVAGLDAR-----GFLIGA
MAB_2877c|M.abscessus_ATCC_199 KDLTPLFADADGLSRVTDALAQ---AASGATLIAGIDAR-----GFLLGA
Mb2615c|M.bovis_AF2122/97 KDLTPLFADRRGLAAVTEALAD---RASGADLVAGVDAR-----GFLVAA
Rv2584c|M.tuberculosis_H37Rv KDLTPLFADRRGLAAVTEALAD---RASGADLVAGVDAR-----GFLVAA
MMAR_2123|M.marinum_M KDLTPLFADREAMAAVIDALAD---IAAGTDLVAGIESR-----GSLVAA
MUL_1728|M.ulcerans_Agy99 KDLTPLFADREAMAAVIDALAD---IAAGTDLVAGIESR-----GSLVAA
MAV_3465|M.avium_104 KDLTPLFADATAMTAVTGALAR---HASGADLVAGIDSR-----GFLVAA
MLBr_00248|M.leprae_Br4923 YPYARQDKKHRGREPISARLVADLLKTAGADRIVTVDLHTDQIQGFFDGP
: . . : :. *: :. :: : * : .
Mflv_3813|M.gilvum_PYR-GCK AVAVT---LGIGVLA-----------------VRKGGKLPPPVLGETYTL
Mvan_2586|M.vanbaalenii_PYR-1 AVAVT---LGIGVLA-----------------VRKGGKLPPPVIGATYTL
MSMEG_2964|M.smegmatis_MC2_155 AVATR---LGTGVLA-----------------VRKGGKLPPPVHGATYQL
TH_0744|M.thermoresistible__bu AVAIR---LGTGVLA-----------------VRKGGKLPPPVRSESYVL
MAB_2877c|M.abscessus_ATCC_199 AVAIR---LGVGVLA-----------------VRKAGKLPPPVHAQTYQL
Mb2615c|M.bovis_AF2122/97 AVATR---LEVGVLA-----------------VRKGGKLPRPVLSEEYYR
Rv2584c|M.tuberculosis_H37Rv AVATR---LEVGVLA-----------------VRKGGKLPRPVLSEEYYR
MMAR_2123|M.marinum_M ALAAR---LGTGVLS-----------------IRKSGKLPPPVLTEEYDR
MUL_1728|M.ulcerans_Agy99 ALAAR---LGTGVLS-----------------IRKSGKLPPPVLTEEYDR
MAV_3465|M.avium_104 AVADR---LHTGVLA-----------------IRKGGKLPPPVHAERYDL
MLBr_00248|M.leprae_Br4923 VDHMRGQNLLTGYIKNNYPDTNMVVVSPDSGRVRIAEKWGDALGGVPLAF
. * * : :* . * .:
Mflv_3813|M.gilvum_PYR-GCK EYGSATLEVPADGV------ELAGRSVVVIDDVLATGGTLAAAHQLLTKA
Mvan_2586|M.vanbaalenii_PYR-1 EYGTATLEVPAEGI------ELAGRSVVVIDDVLATGGTLAATHQLLTRA
MSMEG_2964|M.smegmatis_MC2_155 EYGTATLEIPAEGI------DIAGRNVVIIDDVLATGGTLAAAARLLGDC
TH_0744|M.thermoresistible__bu EYGTASLEIPAEGI------DLTGQRVVIVDDVLATGGTVAAAARLLRSA
MAB_2877c|M.abscessus_ATCC_199 EYGTAALEIPADGV------ELAGRRVAIVDDVLATGGTLAATARLLTTA
Mb2615c|M.bovis_AF2122/97 EYGAATLEILAEGI------EVAGRRVVIIDDVLATGGTIGATRRLLERG
Rv2584c|M.tuberculosis_H37Rv AYGAATLEILAEGI------EVAGRRVVIIDDVLATGGTIGATRRLLERG
MMAR_2123|M.marinum_M EYGAASMEIPADSL------ELRGRSVMIIDDVLATGGTLGAATRLLKRT
MUL_1728|M.ulcerans_Agy99 EYGAASMEIPADSL------ELRGRSVMIIDDVLATGGTLGAATRLLERT
MAV_3465|M.avium_104 EYGSATLEIPADGI------DLRGRRIVIIDDVLATGGTLAAAARLLRRT
MLBr_00248|M.leprae_Br4923 IHKTRDLRVPNQVVSNRVVGEVEGRTCVLIDDMIDTGGTVAGAVQLLRND
: : :.: : : :: *: ::**:: ****:..: :**
Mflv_3813|M.gilvum_PYR-GCK GAN---------VTGAVVMMELTALGGRA---------------------
Mvan_2586|M.vanbaalenii_PYR-1 GAN---------VTGAVVMMELAALGGRA---------------------
MSMEG_2964|M.smegmatis_MC2_155 GAN---------VTGAGVVLELEALRGRE---------------------
TH_0744|M.thermoresistible__bu GAT---------VSGVAVVLELGGLGGRA---------------------
MAB_2877c|M.abscessus_ATCC_199 GAD---------VISAGVVLELSDLGGRA---------------------
Mb2615c|M.bovis_AF2122/97 GAN---------VAGAAVVVELAGLSGRA---------------------
Rv2584c|M.tuberculosis_H37Rv GAN---------VAGAAVVVELAGLSGRA---------------------
MMAR_2123|M.marinum_M GAR---------VTGAAVVVELTALRGRE---------------------
MUL_1728|M.ulcerans_Agy99 GAR---------VTGAAVVVELTALRGRE---------------------
MAV_3465|M.avium_104 GAT---------VTAAAVVFELGALGGRA---------------------
MLBr_00248|M.leprae_Br4923 GASDVIIAATHGVLSPPAAERLAQYGTREVIVTNTLPIGEEKRFPQLTVL
** * . . .* *
Mflv_3813|M.gilvum_PYR-GCK AVDPLEVTSLYSV--------------
Mvan_2586|M.vanbaalenii_PYR-1 ALEPLEVTSLYTA--------------
MSMEG_2964|M.smegmatis_MC2_155 AVAPLGVRSLHII--------------
TH_0744|M.thermoresistible__bu ALEPLPVSSLYTT--------------
MAB_2877c|M.abscessus_ATCC_199 AVAPLPLTALRAI--------------
Mb2615c|M.bovis_AF2122/97 ALAPLPVHSLSRL--------------
Rv2584c|M.tuberculosis_H37Rv ALAPLPVHSLSRL--------------
MMAR_2123|M.marinum_M AIAPLRVHSLSRA--------------
MUL_1728|M.ulcerans_Agy99 AIAPLRVHSLSRA--------------
MAV_3465|M.avium_104 ALAPLPVHRLTCQ--------------
MLBr_00248|M.leprae_Br4923 SIAPLLASTIRAIFENGSVTGLFDGEA
:: ** :