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M. bovis AF2122 / 97 Mb2615c (apt)

annotation: adenine phosphoribosyltransferase
coordinates: 2877677 - 2878348
length: 223

VCHGGTWAGDYVLNVIATGLSLKARGKRRRQRWVDDGRVLALGESRRSSAISVADVVASLTRDVADFPVP
GVEFKDLTPLFADRRGLAAVTEALADRASGADLVAGVDARGFLVAAAVATRLEVGVLAVRKGGKLPRPVL
SEEYYREYGAATLEILAEGIEVAGRRVVIIDDVLATGGTIGATRRLLERGGANVAGAAVVVELAGLSGRA
ALAPLPVHSLSRL
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2615capt-100% (223)adenine phosphoribosyltransferase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCKMflv_3813-5e-5765.48% (168) adenine phosphoribosyltransferase
M. tuberculosis H37RvRv2584capt1e-12099.55% (223) adenine phosphoribosyltransferase
M. leprae Br4923MLBr_02487pyrE1e-0529.11% (79) orotate phosphoribosyltransferase
M. abscessus ATCC 19977MAB_2877c-5e-5967.86% (168) adenine phosphoribosyltransferase
M. marinum MMMAR_2123apt1e-6270.00% (170) adenine phosphoribosyltransferase, Apt
M. avium 104MAV_3465-1e-6169.77% (172) adenine phosphoribosyltransferase
M. smegmatis MC2 155MSMEG_2964-7e-6071.43% (168) adenine phosphoribosyltransferase
M. thermoresistible (build 8)TH_0744apt4e-5866.08% (171) ADENINE PHOSPHORIBOSYLTRANSFERASE APT (APRT) (AMP
M. ulcerans Agy99MUL_1728apt3e-6370.59% (170) adenine phosphoribosyltransferase
M. vanbaalenii PYR-1Mvan_2586-1e-5969.05% (168) adenine phosphoribosyltransferase

CLUSTAL 2.0.9 multiple sequence alignment


Mb2615c|M.bovis_AF2122/97           MCHGGTWAGDYVLNVIATGLSLKARGKRRRQRWVDDGRVLALGESRRSSA
Rv2584c|M.tuberculosis_H37Rv        MCHGGTWAGDYVLNVIATGLSLKARGKRRRQRWVDDGRVLALGESRRSSA
MMAR_2123|M.marinum_M               -----------MTDLVVTGR----------------------------GS
MUL_1728|M.ulcerans_Agy99           -----------MTDLVVTGR----------------------------GS
MAV_3465|M.avium_104                -----------MTD---AG-----------------------------EA
MAB_2877c|M.abscessus_ATCC_199      MTG----------------------------------------------P
MSMEG_2964|M.smegmatis_MC2_155      MTQHH-------------------------------------------DT
Mflv_3813|M.gilvum_PYR-GCK          MSGE--------------------------------------------PG
Mvan_2586|M.vanbaalenii_PYR-1       -------------------------------------------------M
TH_0744|M.thermoresistible__bu      MSGAG-------------------------------------------YA
MLBr_02487|M.leprae_Br4923          ------------------------------------------------MA
                                                                                      

Mb2615c|M.bovis_AF2122/97           ISVADVVASLTRDVADFPVPGVEFKDLTPLFADRRGLAAVTEALADRASG
Rv2584c|M.tuberculosis_H37Rv        ISVADVVASLTRDVADFPVPGVEFKDLTPLFADRRGLAAVTEALADRASG
MMAR_2123|M.marinum_M               APVADLISSLTRDVADFPKPGIQFKDLTPLFADREAMAAVIDALADIAAG
MUL_1728|M.ulcerans_Agy99           APVADLISSLTRDVADFPKPGIQFKDLTPLFADREAMAAVIDALADIAAG
MAV_3465|M.avium_104                TPVAELIASLTRQVPDFPKPGIQFKDLTPLFADATAMTAVTGALARHASG
MAB_2877c|M.abscessus_ATCC_199      DEIAELVASLTREVADFPEPGVQFKDLTPLFADADGLSRVTDALAQAASG
MSMEG_2964|M.smegmatis_MC2_155      AEVSRVIATLTREVADFPEPGIQFKDLTPLLADARGLRVVTDALADIASG
Mflv_3813|M.gilvum_PYR-GCK          TDIAEVIRSLMREVPDFPEPGVHFKDLTPVLADAYGLAEVSRAIADSARG
Mvan_2586|M.vanbaalenii_PYR-1       TDIADVIRSLMREVPDFPEPGVHFKDLTPVLADARGLAEVSKAIADAARG
TH_0744|M.thermoresistible__bu      ADAAALIAAHLREVADFPEPGIQFKDLTPVLADARALTVVTDALAANIGG
MLBr_02487|M.leprae_Br4923          ELDRKELADLVRRLSVVQG-CVTLSSGKQADHYVDLRRATLHHRASALIG
                                          :    * :. .    : :.. .           .    *    *

Mb2615c|M.bovis_AF2122/97           ADLVAGVDARGFLVAAAVATRLE-VGVLAVRKGGKLPRPVLSEEYYREYG
Rv2584c|M.tuberculosis_H37Rv        ADLVAGVDARGFLVAAAVATRLE-VGVLAVRKGGKLPRPVLSEEYYRAYG
MMAR_2123|M.marinum_M               TDLVAGIESRGSLVAAALAARLG-TGVLSIRKSGKLPPPVLTEEYDREYG
MUL_1728|M.ulcerans_Agy99           TDLVAGIESRGSLVAAALAARLG-TGVLSIRKSGKLPPPVLTEEYDREYG
MAV_3465|M.avium_104                ADLVAGIDSRGFLVAAAVADRLH-TGVLAIRKGGKLPPPVHAERYDLEYG
MAB_2877c|M.abscessus_ATCC_199      ATLIAGIDARGFLLGAAVAIRLG-VGVLAVRKAGKLPPPVHAQTYQLEYG
MSMEG_2964|M.smegmatis_MC2_155      ADLVAGLDARGFLLGAAVATRLG-TGVLAVRKGGKLPPPVHGATYQLEYG
Mflv_3813|M.gilvum_PYR-GCK          ADLVAGVDARGFLLGGAVAVTLG-IGVLAVRKGGKLPPPVLGETYTLEYG
Mvan_2586|M.vanbaalenii_PYR-1       ADLVAGVDARGFLLGGAVAVTLG-IGVLAVRKGGKLPPPVIGATYTLEYG
TH_0744|M.thermoresistible__bu      ADLVAGLDARGFLIGAAVAIRLG-TGVLAVRKGGKLPPPVRSESYVLEYG
MLBr_02487|M.leprae_Br4923          RLMRELTKDWNYTVVGGLTLGADPVAIAIIHSPGRPIDAFVVRKYAKTHG
                                      :    .  .  : ..::      .:  ::. *:   ..    *   :*

Mb2615c|M.bovis_AF2122/97           AATLEILAEGIEVAGRRVVIIDDVLATGGTIGATRRLLERGGANVAGAAV
Rv2584c|M.tuberculosis_H37Rv        AATLEILAEGIEVAGRRVVIIDDVLATGGTIGATRRLLERGGANVAGAAV
MMAR_2123|M.marinum_M               AASMEIPADSLELRGRSVMIIDDVLATGGTLGAATRLLKRTGARVTGAAV
MUL_1728|M.ulcerans_Agy99           AASMEIPADSLELRGRSVMIIDDVLATGGTLGAATRLLERTGARVTGAAV
MAV_3465|M.avium_104                SATLEIPADGIDLRGRRIVIIDDVLATGGTLAAAARLLRRTGATVTAAAV
MAB_2877c|M.abscessus_ATCC_199      TAALEIPADGVELAGRRVAIVDDVLATGGTLAATARLLTTAGADVISAGV
MSMEG_2964|M.smegmatis_MC2_155      TATLEIPAEGIDIAGRNVVIIDDVLATGGTLAAAARLLGDCGANVTGAGV
Mflv_3813|M.gilvum_PYR-GCK          SATLEVPADGVELAGRSVVVIDDVLATGGTLAAAHQLLTKAGANVTGAVV
Mvan_2586|M.vanbaalenii_PYR-1       TATLEVPAEGIELAGRSVVVIDDVLATGGTLAATHQLLTRAGANVTGAVV
TH_0744|M.thermoresistible__bu      TASLEIPAEGIDLTGQRVVIVDDVLATGGTVAAAARLLRSAGATVSGVAV
MLBr_02487|M.leprae_Br4923          ---LQRLIEGSEVSGQRVLVVEDTSTTGASALTAVRAVQDAGGDVVGVAT
                                       ::   :. :: *: : :::*. :**.:  :: : :   *. * .. .

Mb2615c|M.bovis_AF2122/97           VVELAGLSGRAALAP-------LPVHSLSRL
Rv2584c|M.tuberculosis_H37Rv        VVELAGLSGRAALAP-------LPVHSLSRL
MMAR_2123|M.marinum_M               VVELTALRGREAIAP-------LRVHSLSRA
MUL_1728|M.ulcerans_Agy99           VVELTALRGREAIAP-------LRVHSLSRA
MAV_3465|M.avium_104                VFELGALGGRAALAP-------LPVHRLTCQ
MAB_2877c|M.abscessus_ATCC_199      VLELSDLGGRAAVAP-------LPLTALRAI
MSMEG_2964|M.smegmatis_MC2_155      VLELEALRGREAVAP-------LGVRSLHII
Mflv_3813|M.gilvum_PYR-GCK          MMELTALGGRAAVDP-------LEVTSLYSV
Mvan_2586|M.vanbaalenii_PYR-1       MMELAALGGRAALEP-------LEVTSLYTA
TH_0744|M.thermoresistible__bu      VLELGGLGGRAALEP-------LPVSSLYTT
MLBr_02487|M.leprae_Br4923          VVDRGTGAAEAIKAEGLLYRSVLGLADLGLG
                                    :.:     ..            * :  *