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VLDAVSDARRDGFAVGEDYTVTDRSTGGSRQQRAARLGQAQGHADFIRHRVGALLATDRDIATRVSAATQ GLDELAFEDVPGVDTPAEDGVQAVDFRQAPPPGAPGGMSSGDIDAIDAANRALLQDMLAEYSRLPDGQVK TDRLADIAAIQEALRVPDSHLIYVARPDDPADMIPAVTAVGDPFTADHVSVTVPGVSGTTRQTIATMTQE TRGLREEARVIAHSVGESENVATIAWVGYQPPPVLASWNTVDDDLAQAGAPKLEAFLRDLQAGSHNPGHT TALFGHSYGSLLSGIALKDGASSLVDNAVLYGSPGFDATSPAKLGMNDHNFFVMTTPDDPIRYPARLAPL HGWGSDGADTIGTVGRQGTPARVGIRPQRDHRRIPGPLPLHPSADRRGIHSAG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv2542 | - | - | 100% (403) | hypothetical protein Rv2542 |
| M. tuberculosis H37Rv | Rv2797c | - | 2e-42 | 42.19% (256) | hypothetical protein Rv2797c |
| M. tuberculosis H37Rv | Rv0963c | - | 3e-22 | 33.82% (204) | hypothetical protein Rv0963c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2571 | - | 0.0 | 99.75% (403) | hypothetical protein Mb2571 |
| M. gilvum PYR-GCK | Mflv_1972 | - | 2e-09 | 33.08% (130) | hypothetical protein Mflv_1972 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0252 | - | 4e-05 | 24.34% (419) | hypothetical protein MAB_0252 |
| M. marinum M | MMAR_1913 | - | 5e-43 | 42.19% (256) | hypothetical protein MMAR_1913 |
| M. avium 104 | MAV_3143 | - | 2e-17 | 50.49% (103) | hypothetical protein MAV_3143 |
| M. smegmatis MC2 155 | MSMEG_6381 | - | 9e-26 | 32.05% (337) | hypothetical protein MSMEG_6381 |
| M. thermoresistible (build 8) | TH_2578 | - | 1e-33 | 37.85% (251) | PUTATIVE putative conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_1133 | - | 2e-15 | 45.63% (103) | hypothetical protein MUL_1133 |
| M. vanbaalenii PYR-1 | Mvan_0049 | - | 1e-12 | 26.14% (306) | hypothetical protein Mvan_0049 |
CLUSTAL 2.0.9 multiple sequence alignment
Rv2542|M.tuberculosis_H37Rv ------------------------------------------------ML
Mb2571|M.bovis_AF2122/97 ------------------------------------------------ML
MSMEG_6381|M.smegmatis_MC2_155 --MQLSDIDSWN--VGALQSIAFELR-DELRTIEGVATDLELISRLPGWD
TH_2578|M.thermoresistible__bu MALTFEDVEDWTRKTSTLETLQDELN-QRTTTLAGLQEQLAGIRRLDGWE
MAV_3143|M.avium_104 --------------------------------------------------
MUL_1133|M.ulcerans_Agy99 --------------------------------------------------
MMAR_1913|M.marinum_M MSLTVADIDRWDAQAVREVFHAAIAR-AQVS--LEVSRQLATLSIFANSG
Mflv_1972|M.gilvum_PYR-GCK -MPSRSEVESWETADLDAAASRWRTAGDVLESAFEQHRQNILTPGGTAWE
Mvan_0049|M.vanbaalenii_PYR-1 MAVSVSTVRDSKPDRLVDAADATGRHRSELQTIIAGQRE-SLSHLQEHWS
MAB_0252|M.abscessus_ATCC_1997 MRPTISQLRGWNLDALGKAADAARDNARTLDASLDSCDRVFNDAS--GWY
Rv2542|M.tuberculosis_H37Rv DAVSDARRDGFAVGEDYTVTDRSTGGSRQQRAAR----------------
Mb2571|M.bovis_AF2122/97 DAVSDARRDGFAVGEDYTVTDRSTGGSRQQRAAR----------------
MSMEG_6381|M.smegmatis_MC2_155 SPAADAARGRIGTAKANVLDDAAVIGAVAQLADETAAAVAKLQSQLEAVR
TH_2578|M.thermoresistible__bu GSASRAARQSFDPVDDDIANAAAAVGAVRTQVGETIAELTELRTAISEAK
MAV_3143|M.avium_104 MAGFPDLSQVLAWPTQHLTDAARHWEAVGERSYS----------------
MUL_1133|M.ulcerans_Agy99 --------------------------------------------------
MMAR_1913|M.marinum_M GKTAEAAAHQNAGLRRDLDAHGNEALAVARAADRAADGIVKVQSELAALR
Mflv_1972|M.gilvum_PYR-GCK GDAKDAALDRVTADTSVVRRQGDVHRVAADIAARGSEDIQGARSRVLEAI
Mvan_0049|M.vanbaalenii_PYR-1 GQAASAALARGLDDIARQDRVAGRLLNLESALRNGGLQMGALRDALLDLV
MAB_0252|M.abscessus_ATCC_1997 GKTHDAAKIKVDQELDHGREIRNVLNRISDDAEDAARTLKHAKEFTLQDV
Rv2542|M.tuberculosis_H37Rv --------------------------------LGQAQGHADFIRHRVGAL
Mb2571|M.bovis_AF2122/97 --------------------------------LGQAQGHADFIRHRVGAL
MSMEG_6381|M.smegmatis_MC2_155 ADVAAQGGLLHLAD------NGDVTIGGSPDDREQLKHIAENIEARAKAL
TH_2578|M.thermoresistible__bu QYASANGYAIQFNGRVIDLWDLDDRANATPAELEQHKAAEAELQTMVSEI
MAV_3143|M.avium_104 --------------------------------------VIHQVWRDGLSS
MUL_1133|M.ulcerans_Agy99 --------------------------------------------------
MMAR_1913|M.marinum_M KAAAAAELQIDALSSR---VVPIAGLRHTESEWARVLAKQAELQADLGAI
Mflv_1972|M.gilvum_PYR-GCK AEAEQDDFTVGEDLSVTDN--RAYDLETAAARMTAATEHAEFIRWRVEQL
Mvan_0049|M.vanbaalenii_PYR-1 SSLERFGFAVADDG---------TVTPEQWLVGQFLDSLADKFTGFLQKM
MAB_0252|M.abscessus_ATCC_1997 DGAVSEGFTVTDTG---------EVSHPDAKKAQAAADHQRRIQSGLDEL
Rv2542|M.tuberculosis_H37Rv LATDRDIATRVSAATQGLD-----------ELAFEDVPGVDTPAEDG---
Mb2571|M.bovis_AF2122/97 LATDRDIATRVSAATQGLD-----------ELAFEDVPGVDTPAEDG---
MSMEG_6381|M.smegmatis_MC2_155 IHQAEDIDADCAEVFGHIEN---------GDVTARGSSDFASAQEMGREQ
TH_2578|M.thermoresistible__bu VERGNEIEAESARVLWAANS---------GEISADGLTDVEQATNAG---
MAV_3143|M.avium_104 DWRGRAADALHAATHDDAGK---------TSGVADQLRAAAGVARSG---
MUL_1133|M.ulcerans_Agy99 ---------MRAATHADLQT---------TSAAVDQLQEAARVARNG---
MMAR_1913|M.marinum_M VVEANTIDEELASAVNMADGDSPIPAEAGAPVGPEGLTPTQRASDAN---
Mflv_1972|M.gilvum_PYR-GCK VATDALIGQQLQANAAELEG-IRFEGDRDGNGTDPTIRLVDNKTEDKGSQ
Mvan_0049|M.vanbaalenii_PYR-1 LQLFTDLDENTAAAIDQAAG--VDSPNPPVEVGGQDIHIPSPDTDPAD--
MAB_0252|M.abscessus_ATCC_1997 ARLDDMYGKKLREAADDLES----MRDGQHDVTLPSGERVDPDALVDR--
Rv2542|M.tuberculosis_H37Rv ---------------------------VQAVDFRQAPPPGAPGGMSSGDI
Mb2571|M.bovis_AF2122/97 ---------------------------VQAVDFRQAPPPGAPGGMSSGDI
MSMEG_6381|M.smegmatis_MC2_155 SGLSAPYPPEGEGVSPENVNAWWNALSEEEQAKVISEHPDWIGNRDGVPV
TH_2578|M.thermoresistible__bu ----ARFALEP-GAEPQEVENWWNTLSPEQQEWMIDNRPDWVRNVDGIPT
MAV_3143|M.avium_104 -------------------------------------ASELVAARSRVRY
MUL_1133|M.ulcerans_Agy99 -------------------------------------ASDLYAARSRVRY
MMAR_1913|M.marinum_M -----------------------EELLREERAKLRARIGQLQGRYDQLAA
Mflv_1972|M.gilvum_PYR-GCK AESSEQRGAGSLSEESTGTWQDMLAPEESAESAEGADTAESPLEALLGEG
Mvan_0049|M.vanbaalenii_PYR-1 ------------------VKQWWDSLSEQQRRELIDRHPPMLGNLNGIPA
MAB_0252|M.abscessus_ATCC_1997 ----------VSKMSADERAAFLATLSPETVDAMVIANPEVMGNSDGIPF
Rv2542|M.tuberculosis_H37Rv DAIDAANRALLQDMLAEYSRLPDGQVKTD---------------------
Mb2571|M.bovis_AF2122/97 DAIDAANRALLQDMLAEYSRLPDGQVKTD---------------------
MSMEG_6381|M.smegmatis_MC2_155 AVRSEVNKAALDRELAEAQAAVDAMPSRDEFRREHPGWNGAQLNAAYNKM
TH_2578|M.thermoresistible__bu EVRDESNRIWLPQERARLEDELRQELAANPNPNRPP----------FGMP
MAV_3143|M.avium_104 AVEDAMRSGFDVYEDMSVADRSTGGSAAQR--------------------
MUL_1133|M.ulcerans_Agy99 AVTDAQAAGFQVEEDLSVTDRMTGGSAAQR--------------------
MMAR_1913|M.marinum_M RAACDYNNGILDSDAMGQLAALGDQLTAAKG-------------------
Mflv_1972|M.gilvum_PYR-GCK ETAEGQQRSSLDEALTEVAGKPVDAPPTALERILSQHTG-----------
Mvan_0049|M.vanbaalenii_PYR-1 EVRDQVNVAVMDDDLDRVQNVADRNGVSTDEVAGNPGRYG---------L
MAB_0252|M.abscessus_ATCC_1997 DTRIAANEINIRNALSDELQKQPPDQARVNQLQDMLKPMEDP--------
.
Rv2542|M.tuberculosis_H37Rv ------RLADIAAIQEALRVP------------------------DSHLI
Mb2571|M.bovis_AF2122/97 ------RLADIAAIQEALRVP------------------------DSHLI
MSMEG_6381|M.smegmatis_MC2_155 MFERQGRLDDAKAMKDALSVDGKYDP-------------------NKYLM
TH_2578|M.thermoresistible__bu ARALERKINDLRKIEQVLDQK------------------------DTYLI
MAV_3143|M.avium_104 ----AARQAQAQAFAGDIRRR-----------------------------
MUL_1133|M.ulcerans_Agy99 ----AARQAQAQAFAGDLPQR-----------------------------
MMAR_1913|M.marinum_M ------RLGDLDAVDQALRNAP-----------------------ETYLA
Mflv_1972|M.gilvum_PYR-GCK ----TGRGEDRRYTQHPLEAPIVGAD-------------------SSVIG
Mvan_0049|M.vanbaalenii_PYR-1 TDGDVTRYQNAKRTQEGLLHQLGAQDGETRRYSEIGEQERRDKNWRPTML
MAB_0252|M.abscessus_ATCC_1997 ---LVTRPADAGPRDFMVDRKYVMFSTEG----------------NGRMI
: : :
Rv2542|M.tuberculosis_H37Rv YVARPDDPADMIPAVTAVGDPF-----TADHVSVTVPGVSG--TTRQTIA
Mb2571|M.bovis_AF2122/97 YVARPDDPADMIPAVTAVGDPF-----TADHVSVTVPGVSG--TTRQTIA
MSMEG_6381|M.smegmatis_MC2_155 LLEFPEDR--EPRAAIAVGNPD-----TAEHVTVTTPGVGTRPES---LG
TH_2578|M.thermoresistible__bu GLDTSGD---ATKAILAVGNPD-----EADHVAVTVPGMGSQDDAGSTIE
MAV_3143|M.avium_104 ------------AAELVALDQQ-----VAGRVTAATAGIRD---------
MUL_1133|M.ulcerans_Agy99 ------------AAQLVGLDAQ-----VATKVTAAVAGIGS---------
MMAR_1913|M.marinum_M QLRVPDDPHQQVLAAVAVGNPD-----TAANVSVTVPGVGS--TTRGTLP
Mflv_1972|M.gilvum_PYR-GCK DQQARVDAAHESVESAQGALDD-----ALAQSTVAGAGAGPGRDQLDALG
Mvan_0049|M.vanbaalenii_PYR-1 WAYDPQAFDGKGRAAVSIGNPD-----RASNTAVIVPGTSAS------VR
MAB_0252|M.abscessus_ATCC_1997 EMIGDIKPGVRGVGVIVPGTNTNLNGSGSNHESAVKLAKESGSPIFLYLG
. :. .
Rv2542|M.tuberculosis_H37Rv TMTQETRGLREEARVIAHSVGES-ENVATIAWVGYQ-PPPVLASWNTVDD
Mb2571|M.bovis_AF2122/97 TMTQEARGLREEARVIAHSVGES-ENVATIAWVGYQ-PPPVLASWNTVDD
MSMEG_6381|M.smegmatis_MC2_155 GMVSEADALRQEAQTQLDRAGRSGEQVATIAWLGYEPPGTDISVAEAGFE
TH_2578|M.thermoresistible__bu GMTREGTLMQAEAQTQLERAGRGDETVATVAWMNYDTPPG--LLEGAGSD
MAV_3143|M.avium_104 -------TFPQTPDSDAPQRKPKFQAVDHHTFKEDPPPNGSYPVNEVVAE
MUL_1133|M.ulcerans_Agy99 -------SFPQIPAPAAPPMGNPVRAVDNRTFKQNPPPAPVDPK-DMTAE
MMAR_1913|M.marinum_M GMVTEARNLQSEEMRQLKNAGKP-TSVAAIAWMGYEPPPNPLDTATAGDL
Mflv_1972|M.gilvum_PYR-GCK HVLFEARGEVTSQTEVLEKLNAAADEVGQGRVPIPALPENADVQAFPAEP
Mvan_0049|M.vanbaalenii_PYR-1 DGWLSDGHNDAIHLYGQSLKADPADPTAVISWMGYNTPESFTDPNIANTG
MAB_0252|M.abscessus_ATCC_1997 GDFPQGLDKAADPSYAAAMAPKLVDFGHEVDRAVGQNAPGTPVTYVGHSY
.
Rv2542|M.tuberculosis_H37Rv DLAQAGAPKLEAF---------------------LRDLQAG-SHNPGHTT
Mb2571|M.bovis_AF2122/97 DLAQAGAPKLEAF---------------------LRDLQAG-SHNPGHTT
MSMEG_6381|M.smegmatis_MC2_155 RRANEAAPDLADF---------------------YRGINATNEHGSDVHL
TH_2578|M.thermoresistible__bu ARATGAAPVLSNY---------------------LESIDVTSTGTEEPHL
MAV_3143|M.avium_104 ATDLDGNHVVLRRG--------------------YYNAEK-------REG
MUL_1133|M.ulcerans_Agy99 EARAAWADINSEIG--------------------KYNARCGRTFVLPTEQ
MMAR_1913|M.marinum_M WQTMTDGQARAGAGD------------------LSRYLQQVRANNPSGHL
Mflv_1972|M.gilvum_PYR-GCK SAFTEGSRALSEGSFGLIPDVAHDIDVFRNWSEASSDDRAGAVLDVAGAA
Mvan_0049|M.vanbaalenii_PYR-1 LARAGGDALAWDVN----------------------GLNVTHEAGVPEHV
MAB_0252|M.abscessus_ATCC_1997 GGAIVGTAEQMGLRADR-----------------ILHASSAGTGILPGGY
Rv2542|M.tuberculosis_H37Rv ALFGHSYGSLLSGIALKDG---ASSLVDNAVLYGSPGFDATS--------
Mb2571|M.bovis_AF2122/97 ALFGHSYGSLLSGIALKDG---ASSLVDNAVLYGSPGFDATS--------
MSMEG_6381|M.smegmatis_MC2_155 SAFGHSYGSLTTAQALYELG--ETGVVDDAAFYGSPGLGHTDSTETYISP
TH_2578|M.thermoresistible__bu TLVGHSYGSLAAGLSLQEG---ASDVVDDYVAYGSPGFYAMD--------
MAV_3143|M.avium_104 WGWDKAYWRHG-------VV--NPNVFKDLISHSRPEHQPDG--------
MUL_1133|M.ulcerans_Agy99 GAYDACIADKGPLLDRQAVI--RARLGQLGIPVEGEDPTHPG--------
MMAR_1913|M.marinum_M TVLGHSYGSLTASLALQDLNAHGAHPVNDVVFYGSPGLELYS--------
Mflv_1972|M.gilvum_PYR-GCK PIPGGKLVTEGLEHAVDAVN--AGRHVDDALDAGSAGAHHLPDVPSAPHV
Mvan_0049|M.vanbaalenii_PYR-1 TVIGHSYGSTTVADAFANSG----MQADDAILLGSPGTDVAR--------
MAB_0252|M.abscessus_ATCC_1997 TDPNPNVQRYSMTAPGDPIA-IVQSLPRDVRLSDVPGVDQIPG-------
.
Rv2542|M.tuberculosis_H37Rv -------------------PAKLGMNDHNFFVMTTPDDPIR---------
Mb2571|M.bovis_AF2122/97 -------------------PAKLGMNDHNFFVMTTPDDPIR---------
MSMEG_6381|M.smegmatis_MC2_155 RGVPIEV------MAPIRDESDMFLADGRAFVMSAPGDPISGDPTW----
TH_2578|M.thermoresistible__bu -------------------ESQLGMQQGHVFVMQAPDDPIR---------
MAV_3143|M.avium_104 -------------------TLRYDVLINRVHCASGPLGIAS---------
MUL_1133|M.ulcerans_Agy99 -------------------TAEPPFPPPTRINGLTEHGAQR---------
MMAR_1913|M.marinum_M -------------------PAQLGLEHGHAYVMQAPHDLITG--------
Mflv_1972|M.gilvum_PYR-GCK DQTPDVGGPHGGGGADAGPVGNFGFEDANALLQSSEANGGHLIERH----
Mvan_0049|M.vanbaalenii_PYR-1 ------------------SAADFNLDGGQVYIGDASTDPVGWLGQMGNTL
MAB_0252|M.abscessus_ATCC_1997 --------------IPHNVEGRIGNPLGGLPSATDPDKIPGVTRLDTG--
Rv2542|M.tuberculosis_H37Rv -------------------------------YPARLAPLHGWGSDGADTI
Mb2571|M.bovis_AF2122/97 -------------------------------YPARLAPLHGWGSDGADTI
MSMEG_6381|M.smegmatis_MC2_155 ----------NGVPLPSAGDLGQFGPNPLTLPLEQLSADAAVTPDGVSRE
TH_2578|M.thermoresistible__bu ----------------LVAETPWFGGDPADGSFVQLSTTAGTTPDGVYRE
MAV_3143|M.avium_104 ----------------------------------CQDT-GESLTMRIVVD
MUL_1133|M.ulcerans_Agy99 ----------------------------------VEGRDGHGVNDNAMQD
MMAR_1913|M.marinum_M ------------VVAPLAPLHGWGPDPYLTPGLTELSSQAGFDPGGIWRD
Mflv_1972|M.gilvum_PYR-GCK ----------VGMTSDDLAARMESSGLQTVSTFATADEAASAVSTALREN
Mvan_0049|M.vanbaalenii_PYR-1 PGELNDSLGNMVGPTAGLGADPAFEDFGATRFRAEVPGADMIDPSDHSYY
MAB_0252|M.abscessus_ATCC_1997 ------YYGEFGKHPNQVIVGPDGHGSYWDDPSSDAFHNIAAVIGGGEAT
Rv2542|M.tuberculosis_H37Rv GTVGRQGTPARVGIRPQRDHRRIPGPLPLHPSADRRGIHSAG--------
Mb2571|M.bovis_AF2122/97 GTVGRQGTPARVGIRPQRDHRRIPGPLPLHPSADRRGIHSAG--------
MSMEG_6381|M.smegmatis_MC2_155 GAVAHADYPRPVELPSGEKVLRTPAYNLAVIAAGLADVPGPNGEDRLVR-
TH_2578|M.thermoresistible__bu GASGHSEYPRPFN-ADGTDRLRVTGYNTAAVIAGLSETAVRK--------
MAV_3143|M.avium_104 PRVGRADVPGGEQKGVITMFPLEGGSGVIQLGPKWTWTPPWVNN-NVPIN
MUL_1133|M.ulcerans_Agy99 AVAHPIEPPQFMPDQYGGTWRYIGKDATVSLNENGQVTTAWANSRNGWRN
MMAR_1913|M.marinum_M GVYAHGDYPRVFQDAAGQPQLRMSGYNLAAIAAGLPDNKVGAPLLPPVLG
Mflv_1972|M.gilvum_PYR-GCK QDVLNSWIAEGAPRKLELEAPFDGGAVLVQGATEAVTGSTVRVVLKGDGN
Mvan_0049|M.vanbaalenii_PYR-1 YTVGSESLRSMTEIVTGNGGRLDELGLLAQPRTELTVSTPQQLDVPVLGE
MAB_0252|M.abscessus_ATCC_1997 GYVERGIQTNYVDINVGDDGNFRAEAWDQSRAAAGAQVPGLPWDDPGTID
Rv2542|M.tuberculosis_H37Rv -------------------------------
Mb2571|M.bovis_AF2122/97 -------------------------------
MSMEG_6381|M.smegmatis_MC2_155 -------------------------------
TH_2578|M.thermoresistible__bu -------------------------------
MAV_3143|M.avium_104 -------------------------------
MUL_1133|M.ulcerans_Agy99 P------------------------------
MMAR_1913|M.marinum_M GGMPAAPGHVLAGGH----------------
Mflv_1972|M.gilvum_PYR-GCK GGWYVLTGFPKP-------------------
Mvan_0049|M.vanbaalenii_PYR-1 VPLPHLEVETPVIYDPEWNRAGGSVTNDHGY
MAB_0252|M.abscessus_ATCC_1997 RRHHPWDNPRVTDHPEHGQKIQVK-------