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M. tuberculosis H37Rv Rv2461c (clpP)

annotation: ATP-dependent Clp protease proteolytic subunit
coordinates: 2763172 - 2763774
length: 200

SQVTDMRSNSQGLSLTDSVYERLLSERIIFLGSEVNDEIANRLCAQILLLAAEDASKDISLYINSPGGSI
SAGMAIYDTMVLAPCDIATYAMGMAASMGEFLLAAGTKGKRYALPHARILMHQPLGGVTGSAADIAIQAE
QFAVIKKEMFRLNAEFTGQPIERIEADSDRDRWFTAAEALEYGFVDHIITRAHVNGEAQ*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv2461cclpP-100% (200)ATP-dependent Clp protease proteolytic subunit
M. tuberculosis H37RvRv2460cclpP27e-3847.09% (172) ATP-dependent Clp protease proteolytic subunit

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2488cclpP1e-110100.00% (200) ATP-dependent Clp protease proteolytic subunit
M. gilvum PYR-GCKMflv_2588clpP5e-9588.14% (194) ATP-dependent Clp protease proteolytic subunit
M. leprae Br4923MLBr_01480clpP1e-10595.00% (200) ATP-dependent Clp protease proteolytic subunit
M. abscessus ATCC 19977MAB_1581clpP2e-8884.29% (191) ATP-dependent Clp protease proteolytic subunit
M. marinum MMMAR_3808clpP1e-10496.97% (198) ATP-dependent Clp protease proteolytic subunit ClpP1
M. avium 104MAV_1713clpP1e-10092.96% (199) ATP-dependent Clp protease proteolytic subunit
M. smegmatis MC2 155MSMEG_4673clpP5e-9991.79% (195) ATP-dependent Clp protease proteolytic subunit
M. thermoresistible (build 8)TH_0352clpP3e-9892.67% (191) PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1
M. ulcerans Agy99MUL_3731clpP1e-10596.97% (198) ATP-dependent Clp protease proteolytic subunit
M. vanbaalenii PYR-1Mvan_4040clpP7e-9589.53% (191) ATP-dependent Clp protease proteolytic subunit

CLUSTAL 2.0.9 multiple sequence alignment


Rv2461c|M.tuberculosis_H37Rv        ------------------------MSQVTDMRSNSQGLSLTDSVYERLLS
Mb2488c|M.bovis_AF2122/97           ------------------------MSQVTDMRSNSQGLSLTDSVYERLLS
MMAR_3808|M.marinum_M               ---------------------------MTDMRSNSQGLNLTDSVYERLLS
MUL_3731|M.ulcerans_Agy99           ---------------------------MTDMRSNSQGLNLTDSVYERLLS
MLBr_01480|M.leprae_Br4923          MIAKQRARFVSVGAYRTPESRYPTVGHVTDIRSNSQGFNLTDSVYERLLS
MAV_1713|M.avium_104                ---------------------------MSDMRSPSQGLNLTDSVYERLLS
Mflv_2588|M.gilvum_PYR-GCK          ----MSFVRPVTASEVHKESRYP---VVTDMRGASSGLNLVDSVYERLLA
Mvan_4040|M.vanbaalenii_PYR-1       ------------------------------MRGASSGLNLVDSVYERLLS
MSMEG_4673|M.smegmatis_MC2_155      ---------------------------MTDMRGTGQGLNLVDSVYERLLA
TH_0352|M.thermoresistible__bu      ------------------------------MRSAGQGLNLVDSVYERLLA
MAB_1581|M.abscessus_ATCC_1997      ------------------------------MRSATAGLNLIDSVYERLLS
                                                                  :*.   *:.* ********:

Rv2461c|M.tuberculosis_H37Rv        ERIIFLGSEVNDEIANRLCAQILLLAAEDASKDISLYINSPGGSISAGMA
Mb2488c|M.bovis_AF2122/97           ERIIFLGSEVNDEIANRLCAQILLLAAEDASKDISLYINSPGGSISAGMA
MMAR_3808|M.marinum_M               ERIIFLGSEVNDEVANRLCAQILLLAAEDASKDINLYINSPGGSISAGMA
MUL_3731|M.ulcerans_Agy99           ERIIFLGSEVNDEVANRLCAQILLLAAEDASKDINLYINSPGGSISAGMA
MLBr_01480|M.leprae_Br4923          ERIIFLGSEVNDNIANRLCAQILLLAAEDAFKDISLYINSPGGSISAGMA
MAV_1713|M.avium_104                ERIIFLGSEVNDDVANRLCAQILLLAAEDPTKDISLYINSPGGSISAGMA
Mflv_2588|M.gilvum_PYR-GCK          ERIIFLGSQVDDDIANRLCAQILLLSAEDPTKDIHLYINSPGGSISAGMA
Mvan_4040|M.vanbaalenii_PYR-1       ERIIFLGSQVDDDIANRLCAQILLLSAEDPTKDIHLYINSPGGSISAGMA
MSMEG_4673|M.smegmatis_MC2_155      ERIIFLGSQVDDDIANRLCAQILLLSAEDPTKDIHLYINSPGGSISAGMA
TH_0352|M.thermoresistible__bu      ERIIFLGSQVDDEIANRLCAQILLLAAEDPTKDISLYINSPGGSISAGMA
MAB_1581|M.abscessus_ATCC_1997      ERIIFLGQQVDDDIANKLCAQILLLTAEDPTKDIHLYINSPGGSISAGMA
                                    *******.:*:*::**:********:***. *** ***************

Rv2461c|M.tuberculosis_H37Rv        IYDTMVLAPCDIATYAMGMAASMGEFLLAAGTKGKRYALPHARILMHQPL
Mb2488c|M.bovis_AF2122/97           IYDTMVLAPCDIATYAMGMAASMGEFLLAAGTKGKRYALPHARILMHQPL
MMAR_3808|M.marinum_M               IYDTMVLAPCDIATYAMGMAASMGEFLLAAGTKGKRYALPHARILMHQPL
MUL_3731|M.ulcerans_Agy99           IYDTMVLAPCDIATYAMGMAASMGEFLLAAGTKGKRYALPHARILMHQPL
MLBr_01480|M.leprae_Br4923          IYDTMVLAPCDIATYAMGMAASMGEFLLAAGTRGKRYALPHARILMHQPL
MAV_1713|M.avium_104                IYDTMVLAPCDIATYAMGMAASMGEFLLAAGTKGKRYALPHARILMHQPL
Mflv_2588|M.gilvum_PYR-GCK          IYDTMVLAPCDVATYAMGMAASMGEFLLAAGTKGKRYALPHARILMHQPL
Mvan_4040|M.vanbaalenii_PYR-1       IYDTMVLAPCDVATYAMGMAASMGEFLLAAGTKGKRYALPHARILMHQPL
MSMEG_4673|M.smegmatis_MC2_155      IYDTMVLAPCDIATYAMGMAASMGEFLLAAGTKGKRYALPHARILMHQPL
TH_0352|M.thermoresistible__bu      IYDTMVLAPCDIATYAMGMAASMGQFLLAAGTKGKRYALPHARILMHQPL
MAB_1581|M.abscessus_ATCC_1997      IFDTMQLSECDIATYAMGMAASMGEFLLAAGTKGKRHALPHARILMHQPL
                                    *:*** *: **:************:*******:***:*************

Rv2461c|M.tuberculosis_H37Rv        GGVTGSAADIAIQAEQFAVIKKEMFRLNAEFTGQPIERIEADSDRDRWFT
Mb2488c|M.bovis_AF2122/97           GGVTGSAADIAIQAEQFAVIKKEMFRLNAEFTGQPIERIEADSDRDRWFT
MMAR_3808|M.marinum_M               GGVTGSAADIAIQAEQFAVIKKEMFRLNAEFTGQSIERIEADSDRDRWFT
MUL_3731|M.ulcerans_Agy99           GGVTGSAADIAIQAEQFAVIKKEMFRLNAEFTGQSIERIEADSDRDRWFT
MLBr_01480|M.leprae_Br4923          GGVTGSAADIAIQAEQFAVIKKEMFRLNAEFTGQPIERIEADSDRDRWFT
MAV_1713|M.avium_104                GGVTGSAADIAIQAEQFHVIKKEMFRLNAEFTGQSIERIEADSDRDRWFT
Mflv_2588|M.gilvum_PYR-GCK          GGITGGAADIAIQAEQFASIKKEMFRLNAEFTGQTIERIEADSDRDRWFT
Mvan_4040|M.vanbaalenii_PYR-1       GGITGGAADIAIQAEQFAVIKKEMFRLNAEFTGQTIERIEADSDRDRWFT
MSMEG_4673|M.smegmatis_MC2_155      GGVTGSAADIAIQAEQFAVIKKEMFRLNAEFTGQPIERIEADSDRDRWFT
TH_0352|M.thermoresistible__bu      GGVTGSAADIAIQAEQFALIKKEMFRLNAEFTGQPIERIEADSDRDRWFT
MAB_1581|M.abscessus_ATCC_1997      GGVTGSASDIAIQAEQFQVIKKEMFRLNAEFTGKSIEQIEQDSDRDRWFT
                                    **:**.*:*********  **************:.**:** *********

Rv2461c|M.tuberculosis_H37Rv        AAEALEYGFVDHIITR-AHVN-GEAQ------
Mb2488c|M.bovis_AF2122/97           AAEALEYGFVDHIITR-AHVN-GEAQ------
MMAR_3808|M.marinum_M               APEALEYGFVDHIITRAAHVN-GEAQ------
MUL_3731|M.ulcerans_Agy99           APEALEYGFVDHIITRAAHVN-GEAQ------
MLBr_01480|M.leprae_Br4923          ASEALEYGFVDHIITR-AHVN-GEVQ------
MAV_1713|M.avium_104                AQEALEYGFVDHIITRAATITNGEAQ------
Mflv_2588|M.gilvum_PYR-GCK          AQEALEYGFVDHIITS-VNFN-GANNS-----
Mvan_4040|M.vanbaalenii_PYR-1       AQEALEYGFVDHIITS-TNVN-GVTS------
MSMEG_4673|M.smegmatis_MC2_155      AQEALEYGFVDHIITS-ASVN-GEGPGAGLDK
TH_0352|M.thermoresistible__bu      AQEALEYGFVDHVITR-ADVN-GVSNA-----
MAB_1581|M.abscessus_ATCC_1997      APEALEYGFVDKIITR-GNLN-GSKGASK---
                                    * *********::**    .. *