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M. tuberculosis H37Rv Rv2460c (clpP2)

annotation: ATP-dependent Clp protease proteolytic subunit
coordinates: 2762531 - 2763175
length: 214

NSQNSQIQPQARYILPSFIEHSSFGVKESNPYNKLFEERIIFLGVQVDDASANDIMAQLLVLESLDPDRD
ITMYINSPGGGFTSLMAIYDTMQYVRADIQTVCLGQAASAAAVLLAAGTPGKRMALPNARVLIHQPSLSG
VIQGQFSDLEIQAAEIERMRTLMETTLARHTGKDAGVIRKDTDRDKILTAEEAKDYGIIDTVLEYRKLSA
QTA*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv2460cclpP2-100% (214)ATP-dependent Clp protease proteolytic subunit
M. tuberculosis H37RvRv2461cclpP8e-3847.09% (172) ATP-dependent Clp protease proteolytic subunit

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2487cclpP21e-117100.00% (214) ATP-dependent Clp protease proteolytic subunit
M. gilvum PYR-GCKMflv_2589-1e-10691.51% (212) ATP-dependent Clp protease proteolytic subunit
M. leprae Br4923MLBr_01479clpP21e-11497.18% (213) ATP-dependent Clp protease proteolytic subunit
M. abscessus ATCC 19977MAB_1582-1e-10490.48% (210) ATP-dependent Clp protease proteolytic subunit
M. marinum MMMAR_3807clpP21e-11297.14% (210) ATP-dependent Clp protease proteolytic subunit ClpP2
M. avium 104MAV_1714clpP1e-11397.62% (210) ATP-dependent Clp protease proteolytic subunit
M. smegmatis MC2 155MSMEG_4672clpP1e-10993.40% (212) ATP-dependent Clp protease proteolytic subunit
M. thermoresistible (build 8)TH_3079-1e-10692.31% (208) PUTATIVE Clp protease
M. ulcerans Agy99MUL_3730clpP21e-11297.14% (210) ATP-dependent Clp protease proteolytic subunit
M. vanbaalenii PYR-1Mvan_4039-1e-10894.23% (208) ATP-dependent Clp protease proteolytic subunit

CLUSTAL 2.0.9 multiple sequence alignment


Rv2460c|M.tuberculosis_H37Rv        ------MNSQNSQIQPQARYILPSFIEHSSFGVKESNPYNKLFEERIIFL
Mb2487c|M.bovis_AF2122/97           ------MNSQNSQIQPQARYILPSFIEHSSFGVKESNPYNKLFEERIIFL
MLBr_01479|M.leprae_Br4923          ------MKLQNSQLQPQARYILPSFIEHSSFGVKESNPYNKLFEERIIFL
MAV_1714|M.avium_104                ---------MNPQIQPQARYILPSFIEHSSFGIKESNPYNKLFEERIIFL
MMAR_3807|M.marinum_M               ---------MNPQVQPQARYILPSFIEHSSFGVKESNPYNKLFEERIIFL
MUL_3730|M.ulcerans_Agy99           ---------MNPQVQPQARYILPSFIEHSSFGVKESNPYNKLFEERIIFL
Mflv_2589|M.gilvum_PYR-GCK          -----MIDHTDPRLQPQARYILPSFIEHSSFGVKESNPYNKLFEERIIFL
Mvan_4039|M.vanbaalenii_PYR-1       --------MTDPRLQPQARYILPSFIEHSSFGVKESNPYNKLFEERIIFL
TH_3079|M.thermoresistible__bu      MHNLHLPPHLDPRVQPQARYILPSFIEHSSFGVKESNPYNKLFEERIIFL
MSMEG_4672|M.smegmatis_MC2_155      MSN--IHPSLDARLQPQARYILPSFIEHSSFGVKESNPYNKLFEERIIFL
MAB_1582|M.abscessus_ATCC_1997      ----MISKHLNPELAPQARYILPSFIEHSSFGVKESNPYNKLFEERIIFL
                                              :..: *****************:*****************

Rv2460c|M.tuberculosis_H37Rv        GVQVDDASANDIMAQLLVLESLDPDRDITMYINSPGGGFTSLMAIYDTMQ
Mb2487c|M.bovis_AF2122/97           GVQVDDASANDIMAQLLVLESLDPDRDITMYINSPGGGFTSLMAIYDTMQ
MLBr_01479|M.leprae_Br4923          GVQVDDASANDIMAQLLVLESLDPDRDITMYINSPGGGFTSLMAIYDTMQ
MAV_1714|M.avium_104                GVQVDDASANDIMAQLLVLESLDPDRDITMYINSPGGGFTSLMAIYDTMQ
MMAR_3807|M.marinum_M               GVQVDDASANDIMAQLLVLESLDPDRDITMYINSPGGGFTSLMAIYDTMQ
MUL_3730|M.ulcerans_Agy99           GVQVDDASANDIMAQLLVLESLDPDRDITMYINSPGGGFTSLMAIYDTMQ
Mflv_2589|M.gilvum_PYR-GCK          GVQVDDASANDIMAQLLVLESLDPDRDITMYINSPGGSFTSLMAIYDTMQ
Mvan_4039|M.vanbaalenii_PYR-1       GVQVDDASANDIMAQLLVLESLDPDRDITMYINSPGGSFTSLMAIYDTMQ
TH_3079|M.thermoresistible__bu      GVQVDDASANDVMAQLLVLESLDPDRDITMYINSPGGSFTSLMAIYDTMQ
MSMEG_4672|M.smegmatis_MC2_155      GVQVDDASANDIMAQLLVLESLDPDRDITMYINSPGGSFTSLMAIYDTMQ
MAB_1582|M.abscessus_ATCC_1997      GVQVDDASANDIMAQLLVLESLDPDREITMYINSPGGSFTSLMAIYDTMQ
                                    ***********:**************:**********.************

Rv2460c|M.tuberculosis_H37Rv        YVRADIQTVCLGQAASAAAVLLAAGTPGKRMALPNARVLIHQPSLSGVIQ
Mb2487c|M.bovis_AF2122/97           YVRADIQTVCLGQAASAAAVLLAAGTPGKRMALPNARVLIHQPSLSGVIQ
MLBr_01479|M.leprae_Br4923          YVRADIQTVCLGQAASAAAVLLAAGTPGKRMALPNARVLIHQPSLAGVIQ
MAV_1714|M.avium_104                YVRADIQTVCLGQAASAAAVLLAAGTPGKRMALPNARVLIHQPSLQGVIQ
MMAR_3807|M.marinum_M               YVRADIQTVCLGQAASAAAVLLAAGTPGKRMALPNARVLIHQPSLSGVIQ
MUL_3730|M.ulcerans_Agy99           YVRADIQTVCLGQAASAAAVLLAAGTPGKRMALPNARVLIHQPSLSGVIQ
Mflv_2589|M.gilvum_PYR-GCK          YVRADIQTVCLGQAASAAAVLLAAGTPGKRMALPNARVLIHQPALGGVIQ
Mvan_4039|M.vanbaalenii_PYR-1       YVRADIQTVCLGQAASAAAVLLAAGTPGKRMALPNARILIHQPALGGVIQ
TH_3079|M.thermoresistible__bu      YVRADIQTVCLGQAASAAAVLLAAGTKGKRMALPNARVLIHQPALAGVIQ
MSMEG_4672|M.smegmatis_MC2_155      YVRADIQTVCLGQAASAAAVLLAAGTPGKRLALPNARVLIHQPALSGVIQ
MAB_1582|M.abscessus_ATCC_1997      YVRSDIRTVVLGQAASAAAVLLAAGTPGKRMALPNARVLIHQPALSGVIQ
                                    ***:**:** **************** ***:******:*****:* ****

Rv2460c|M.tuberculosis_H37Rv        GQFSDLEIQAAEIERMRTLMETTLARHTGKDAGVIRKDTDRDKILTAEEA
Mb2487c|M.bovis_AF2122/97           GQFSDLEIQAAEIERMRTLMETTLARHTGKDAGVIRKDTDRDKILTAEEA
MLBr_01479|M.leprae_Br4923          GQFSDLEIQAAEIERMRTLMETTLSRHTGKDAAVIRKDTDRDKILTAEEA
MAV_1714|M.avium_104                GQFSDLEIQAAEIERMRTLMETTLARHTGKDAATIRKDTDRDKILTAEEA
MMAR_3807|M.marinum_M               GQFSDLEIQAAEIERMRTLMESTLARHTGKDPSVIRKDTDRDKILTAEEA
MUL_3730|M.ulcerans_Agy99           GQFSDLEIQAAEIERMRTLMESTLARHTGKDPSVIRKDTDRDKILTAEEA
Mflv_2589|M.gilvum_PYR-GCK          GQFSDLEIQAAEIERMRTLMEETLSLHTGKPADVIRKDTDRDKILTAAAA
Mvan_4039|M.vanbaalenii_PYR-1       GQFSDLEIQAAEIERMRTLMEETLARHTGKDAAQIRKDTDRDKILTAEQA
TH_3079|M.thermoresistible__bu      GQFSDLEIQAAEVERMRTLMEHTLAHHTGKDPETIRRDTDRDKILTAEQA
MSMEG_4672|M.smegmatis_MC2_155      GQFSDLEIQAAEIERMRTLMETTLARHTGKDPAQIRKDTDRDKILTAEEA
MAB_1582|M.abscessus_ATCC_1997      GQFTDLEIQAAEIERMRVLQETTLARHTGRPAEEIRKDTDRDKIFTAEEA
                                    ***:********:****.* * **: ***: .  **:*******:**  *

Rv2460c|M.tuberculosis_H37Rv        KDYGIIDTVLEYRKLSAQTA-
Mb2487c|M.bovis_AF2122/97           KDYGIIDTVLEYRKLSAQTA-
MLBr_01479|M.leprae_Br4923          KDYGIIDTVLEYRKLSAQTV-
MAV_1714|M.avium_104                KDYGIIDTVLEYRKLSAQTA-
MMAR_3807|M.marinum_M               KDYGIIDTVLEYRKLSAQNA-
MUL_3730|M.ulcerans_Agy99           KDYGIIDTVLEYRKLSAQNA-
Mflv_2589|M.gilvum_PYR-GCK          KDYGIIDTVLEYRKLSAQKG-
Mvan_4039|M.vanbaalenii_PYR-1       KEYGIIDTVLEYRKLSAQKA-
TH_3079|M.thermoresistible__bu      KEYGIIDTVLEYRKLSAQTA-
MSMEG_4672|M.smegmatis_MC2_155      KEYGIIDTVLQYRKLSAQTS-
MAB_1582|M.abscessus_ATCC_1997      KEYGIIDVVLEYRKLSAQTAS
                                    *:*****.**:*******.