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M. tuberculosis H37Rv Rv2428 (ahpC)

annotation: ALKYL HYDROPEROXIDE REDUCTASE C PROTEIN AHPC (ALKYL HYDROPEROXIDASE C)
coordinates: 2726193 - 2726780
length: 195

MPLLTIGDQFPAYQLTALIGGDLSKVDAKQPGDYFTTITSDEHPGKWRVVFFWPKDFTFVCPTEIAAFSK
LNDEFEDRDAQILGVSIDSEFAHFQWRAQHNDLKTLPFPMLSDIKRELSQAAGVLNADGVADRVTFIVDP
NNEIQFVSATAGSVGRNVDEVLRVLDALQSDELCACNWRKGDPTLDAGELLKASA
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv2428ahpC-100% (195)ALKYL HYDROPEROXIDE REDUCTASE C PROTEIN AHPC (ALKYL HYDROPEROXIDASE C)
M. tuberculosis H37RvRv2238cahpE2e-0834.65% (101) peroxiredoxin AhpE
M. tuberculosis H37RvRv1608cbcpB4e-0726.19% (126) peroxidoxin BcpB

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2454ahpC1e-113100.00% (195) alkyl hydroperoxide reductase subunit C
M. gilvum PYR-GCKMflv_2535-4e-0825.31% (162) alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal
M. leprae Br4923MLBr_02042ahpC3e-9986.67% (195) alkyl hydroperoxide reductase
M. abscessus ATCC 19977MAB_4408c-8e-9783.77% (191) putative alkylhydroperoxidase C
M. marinum MMMAR_2755ahpC1e-10491.79% (195) alkyl hydroperoxide reductase C protein AhpC
M. avium 104MAV_2839-1e-10290.26% (195) alkylhydroperoxide reductase
M. smegmatis MC2 155MSMEG_4891-1e-9582.20% (191) alkylhydroperoxide reductase
M. thermoresistible (build 8)TH_1778ahpC1e-9683.51% (194) ALKYL HYDROPEROXIDE REDUCTASE C PROTEIN AHPC (ALKYL
M. ulcerans Agy99MUL_2999ahpC1e-10491.79% (195) alkyl hydroperoxide reductase C protein AhpC
M. vanbaalenii PYR-1Mvan_1420-2e-1928.21% (195) peroxiredoxin

CLUSTAL 2.0.9 multiple sequence alignment


Rv2428|M.tuberculosis_H37Rv         MPLLTIGDQFPAYQLTALIGGDLSKVDAKQPGDYFTTITSDEHPGKWRVV
Mb2454|M.bovis_AF2122/97            MPLLTIGDQFPAYQLTALIGGDLSKVDAKQPGDYFTTITSDEHPGKWRVV
MMAR_2755|M.marinum_M               MSLLTIGQQFPAYSLTALIGGDLSKVDAKQPGDYFKTVTSDDHAGKWRVV
MUL_2999|M.ulcerans_Agy99           MSLLTIGQQFPAYSLTALIGGDLSKVDAKQPGDYFKTVTSDDHAGKWRVV
MAV_2839|M.avium_104                MPLLTIGDQFPAYELTALIAGDLSKVDAKQPGDYFTTITSEDHAGKWRVV
MLBr_02042|M.leprae_Br4923          MSLLSIGQQFPAYQLTALIGGDLSKVDAQQPGDYFTTVSSDSHPGKWRVV
MSMEG_4891|M.smegmatis_MC2_155      MALLTIGDQFPEYDLTAVVGGDLSKVDAKQPDDYFTRVTSKDYEGKWRII
TH_1778|M.thermoresistible__bu      MALLTIGDQFPAYDLTAVIGGDLSKVDAKQPDDYFTRVTSNDHPGKWRII
MAB_4408c|M.abscessus_ATCC_199      MTLRTIGDEFPAYNLTAVIGGDLSKVNAQQPDDYFTTVTSDDHPGKWRVI
Mvan_1420|M.vanbaalenii_PYR-1       ---MTVNEMPTPVVTMPRIGDPAPSFTAATTQGDIN--FPADYLGRWVIL
Mflv_2535|M.gilvum_PYR-GCK          ----------MPQTPRLEVGDKAPTFS--LPDADGNTVSLSDYKGRKVIV
                                                      :..  ...    .    .     .: *:  ::

Rv2428|M.tuberculosis_H37Rv         FFWPKDFTFVCPTEIAAFSKLNDEFEDRDAQILGVSIDSEFAHFQWRAQH
Mb2454|M.bovis_AF2122/97            FFWPKDFTFVCPTEIAAFSKLNDEFEDRDAQILGVSIDSEFAHFQWRAQH
MMAR_2755|M.marinum_M               FFWPKDFTFVCPTEIAAFGKLNDEFEDRDAQVLGVSIDSEFVHFQWRAQH
MUL_2999|M.ulcerans_Agy99           FFWPKDFTFVCPTEIAAFGKLNDEFDDRDAQVLGVSIDSEFVHFQWRAQH
MAV_2839|M.avium_104                FFWPKDFTFVCPTEIATFGKLNDEFEDRDAQVLGVSIDSEFVHFNWRAQH
MLBr_02042|M.leprae_Br4923          FFWPKDFTFICPTEIAAFGKLNEEFEGRGAQILGVSIDSEFVHFQWRAQH
MSMEG_4891|M.smegmatis_MC2_155      FFWPKDFTFVCPTEIAAFGKLNEDFEDRDAKVLGVSVDNEFVHFQWRAQH
TH_1778|M.thermoresistible__bu      FFWPKDFTFVCPTEIAAFGKLNDEFEDRDAKVIGVSVDNEFVHFQWRAQH
MAB_4408c|M.abscessus_ATCC_199      FFWPKDFTFVCPTEIAAFGRLNDEFADRDTQVLGASVDNEFVHFQWRAQH
Mvan_1420|M.vanbaalenii_PYR-1       FSHPADFTPVCTSEFITFASMQDEFAAYNTDLVGLSVDGLYSHIAWLRTI
Mflv_2535|M.gilvum_PYR-GCK          YFYPAASTPGCTKQACDFRDSLAELNDAGLDIIGISPD----KPEKLAKF
                                    :  *   *  *..:   *     ::   . .::* * *    :       

Rv2428|M.tuberculosis_H37Rv         NDLKTLP--------FPMLSDIKRELSQAAGVLN---ADGVADR----VT
Mb2454|M.bovis_AF2122/97            NDLKTLP--------FPMLSDIKRELSQAAGVLN---ADGVADR----VT
MMAR_2755|M.marinum_M               DDLKNLP--------FPMLADIKRELVAATGVLN---ADGVADR----VT
MUL_2999|M.ulcerans_Agy99           DDLKNLP--------FPMLADIKRELVAAAGVLN---ADGVADR----VT
MAV_2839|M.avium_104                EDLKNLP--------FPMLSDIKRELSLATGVLN---ADGVADR----AT
MLBr_02042|M.leprae_Br4923          EDLKRLP--------FPMLSDIKRELSAASGALN---ADGVADR----VT
MSMEG_4891|M.smegmatis_MC2_155      EDLKTLP--------FPMVSDLKRELTAACGVLN---ADGVADR----AT
TH_1778|M.thermoresistible__bu      EDLKTLP--------FPMASDLKRELSEATGVLN---DEGVADR----AT
MAB_4408c|M.abscessus_ATCC_199      EDLKTLP--------FPMLSDLKRELAEAAGVLN---ADGVADR----AT
Mvan_1420|M.vanbaalenii_PYR-1       KEKISYKGMRDVEVTFPLIDDVTMEVARKYGMIMPGEDTTKAVR----AV
Mflv_2535|M.gilvum_PYR-GCK          RDAEKLT--------FPLLSDPEKKVLEAWGAFGEKTMYGKTVQGVIRST
                                     :             **:  *   ::    * :        : :     .

Rv2428|M.tuberculosis_H37Rv         FIVDPNNEIQFVSATAGSVGRNVDEVLRVLDALQS----DELCACNWRKG
Mb2454|M.bovis_AF2122/97            FIVDPNNEIQFVSATAGSVGRNVDEVLRVLDALQS----DELCACNWRKG
MMAR_2755|M.marinum_M               FIVDPNNEIQFVSATAGSVGRNVDEVLRVLDALQS----DELCACNWRKG
MUL_2999|M.ulcerans_Agy99           FIVDPNNEIQFVSATAGSVGRNVDEVLRVLDALQS----DELCACNWRKG
MAV_2839|M.avium_104                FIVDPNNEIQFVSVTAGSVGRNVEEVLRVLDALQS----DELCACNWRKG
MLBr_02042|M.leprae_Br4923          FIVDPDNDIQFVSVTAGSVGRNVEEVLRVLDALQS----DQLCACNWRKG
MSMEG_4891|M.smegmatis_MC2_155      FIVDPNNEVQFVSVTAGSVGRNVDEVLRVLDALQS----DELCACNWKKG
TH_1778|M.thermoresistible__bu      FIVDPNNEIQFVSVTAGSVGRNVDEVLRVLDALQS----DELCACNWKKG
MAB_4408c|M.abscessus_ATCC_199      FIVDPDNIIQFVSVTAGSVGRNVDEVLRVLDALQS----DELCACNWRKG
Mvan_1420|M.vanbaalenii_PYR-1       FVIDPEGVVRTIIYYPLSTGRNFDELLRVVKALQTADAFDVATPADWRPG
Mflv_2535|M.gilvum_PYR-GCK          FVVDENGKIEVAQYNVRATG-HVAKLRRDLSV------------------
                                    *::* :. :.       :.* :. :: * :..                  

Rv2428|M.tuberculosis_H37Rv         DPTLDAGELLKASA-----------------------------------
Mb2454|M.bovis_AF2122/97            DPTLDAGELLKASA-----------------------------------
MMAR_2755|M.marinum_M               DPTLDAGELLKASA-----------------------------------
MUL_2999|M.ulcerans_Agy99           DPTLDAGELLKASA-----------------------------------
MAV_2839|M.avium_104                DPTLNATELLKASA-----------------------------------
MLBr_02042|M.leprae_Br4923          DPTLNATELLKTSA-----------------------------------
MSMEG_4891|M.smegmatis_MC2_155      DPTINAGELLAGAV-----------------------------------
TH_1778|M.thermoresistible__bu      DPTINVAEELTKAV-----------------------------------
MAB_4408c|M.abscessus_ATCC_199      DPTINAGELMSAGV-----------------------------------
Mvan_1420|M.vanbaalenii_PYR-1       DAVIVPPAGSCGTAQSRMSGDVVGVECQDWFFCTRELPADEVEARIRRR
Mflv_2535|M.gilvum_PYR-GCK          -------------------------------------------------