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M. leprae Br4923 MLBr_02042 (ahpC)

annotation: alkyl hydroperoxide reductase
coordinates: 2432954 - 2433541
length: 195

MSLLSIGQQFPAYQLTALIGGDLSKVDAQQPGDYFTTVSSDSHPGKWRVVFFWPKDFTFICPTEIAAFGK
LNEEFEGRGAQILGVSIDSEFVHFQWRAQHEDLKRLPFPMLSDIKRELSAASGALNADGVADRVTFIVDP
DNDIQFVSVTAGSVGRNVEEVLRVLDALQSDQLCACNWRKGDPTLNATELLKTSA
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. leprae Br4923MLBr_02042ahpC-100% (195)alkyl hydroperoxide reductase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2454ahpC7e-9986.67% (195) alkyl hydroperoxide reductase subunit C
M. gilvum PYR-GCKMflv_3603-1e-0729.27% (123) alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal
M. tuberculosis H37RvRv2428ahpC7e-9986.67% (195) alkyl hydroperoxide reductase subunit C
M. abscessus ATCC 19977MAB_4408c-7e-9380.63% (191) putative alkylhydroperoxidase C
M. marinum MMMAR_2755ahpC1e-9886.67% (195) alkyl hydroperoxide reductase C protein AhpC
M. avium 104MAV_2839-8e-9986.15% (195) alkylhydroperoxide reductase
M. smegmatis MC2 155MSMEG_4891-1e-9179.06% (191) alkylhydroperoxide reductase
M. thermoresistible (build 8)TH_1778ahpC6e-9279.06% (191) ALKYL HYDROPEROXIDE REDUCTASE C PROTEIN AHPC (ALKYL
M. ulcerans Agy99MUL_2999ahpC2e-9886.15% (195) alkyl hydroperoxide reductase C protein AhpC
M. vanbaalenii PYR-1Mvan_1420-3e-1727.18% (195) peroxiredoxin

CLUSTAL 2.0.9 multiple sequence alignment


Mb2454|M.bovis_AF2122/97            MPLLTIGDQFPAYQLTALIGGDLSKVDAKQPGDYFTTITSDEHPGKWRVV
Rv2428|M.tuberculosis_H37Rv         MPLLTIGDQFPAYQLTALIGGDLSKVDAKQPGDYFTTITSDEHPGKWRVV
MMAR_2755|M.marinum_M               MSLLTIGQQFPAYSLTALIGGDLSKVDAKQPGDYFKTVTSDDHAGKWRVV
MUL_2999|M.ulcerans_Agy99           MSLLTIGQQFPAYSLTALIGGDLSKVDAKQPGDYFKTVTSDDHAGKWRVV
MAV_2839|M.avium_104                MPLLTIGDQFPAYELTALIAGDLSKVDAKQPGDYFTTITSEDHAGKWRVV
MLBr_02042|M.leprae_Br4923          MSLLSIGQQFPAYQLTALIGGDLSKVDAQQPGDYFTTVSSDSHPGKWRVV
MSMEG_4891|M.smegmatis_MC2_155      MALLTIGDQFPEYDLTAVVGGDLSKVDAKQPDDYFTRVTSKDYEGKWRII
TH_1778|M.thermoresistible__bu      MALLTIGDQFPAYDLTAVIGGDLSKVDAKQPDDYFTRVTSNDHPGKWRII
MAB_4408c|M.abscessus_ATCC_199      MTLRTIGDEFPAYNLTAVIGGDLSKVNAQQPDDYFTTVTSDDHPGKWRVI
Mvan_1420|M.vanbaalenii_PYR-1       ---MTVNEMPTPVVTMPRIGDPAPSFTAATTQGDIN--FPADYLGRWVIL
Mflv_3603|M.gilvum_PYR-GCK          MEIVNRGDRVTEFELPDQTGTTRTLTGLLADG--------------PVVL
                                        . .:  .        .   .                        ::

Mb2454|M.bovis_AF2122/97            FFWPKDFTFVCPTEIAAFSKLNDEFEDRDAQILGVSIDSEFAHFQWRAQH
Rv2428|M.tuberculosis_H37Rv         FFWPKDFTFVCPTEIAAFSKLNDEFEDRDAQILGVSIDSEFAHFQWRAQH
MMAR_2755|M.marinum_M               FFWPKDFTFVCPTEIAAFGKLNDEFEDRDAQVLGVSIDSEFVHFQWRAQH
MUL_2999|M.ulcerans_Agy99           FFWPKDFTFVCPTEIAAFGKLNDEFDDRDAQVLGVSIDSEFVHFQWRAQH
MAV_2839|M.avium_104                FFWPKDFTFVCPTEIATFGKLNDEFEDRDAQVLGVSIDSEFVHFNWRAQH
MLBr_02042|M.leprae_Br4923          FFWPKDFTFICPTEIAAFGKLNEEFEGRGAQILGVSIDSEFVHFQWRAQH
MSMEG_4891|M.smegmatis_MC2_155      FFWPKDFTFVCPTEIAAFGKLNEDFEDRDAKVLGVSVDNEFVHFQWRAQH
TH_1778|M.thermoresistible__bu      FFWPKDFTFVCPTEIAAFGKLNDEFEDRDAKVIGVSVDNEFVHFQWRAQH
MAB_4408c|M.abscessus_ATCC_199      FFWPKDFTFVCPTEIAAFGRLNDEFADRDTQVLGASVDNEFVHFQWRAQH
Mvan_1420|M.vanbaalenii_PYR-1       FSHPADFTPVCTSEFITFASMQDEFAAYNTDLVGLSVDGLYSHIAWLRTI
Mflv_3603|M.gilvum_PYR-GCK          FFYPAAMTPGCTKEACHFRDLAAEFAAVGATRVGISAD----PVDKQAQF
                                    *  *  :*  *..*   *  :  :*   .:  :* * *     .      

Mb2454|M.bovis_AF2122/97            NDLKTLP--------FPMLSDIKRELSQAAGVLN----ADGVADRVTFIV
Rv2428|M.tuberculosis_H37Rv         NDLKTLP--------FPMLSDIKRELSQAAGVLN----ADGVADRVTFIV
MMAR_2755|M.marinum_M               DDLKNLP--------FPMLADIKRELVAATGVLN----ADGVADRVTFIV
MUL_2999|M.ulcerans_Agy99           DDLKNLP--------FPMLADIKRELVAAAGVLN----ADGVADRVTFIV
MAV_2839|M.avium_104                EDLKNLP--------FPMLSDIKRELSLATGVLN----ADGVADRATFIV
MLBr_02042|M.leprae_Br4923          EDLKRLP--------FPMLSDIKRELSAASGALN----ADGVADRVTFIV
MSMEG_4891|M.smegmatis_MC2_155      EDLKTLP--------FPMVSDLKRELTAACGVLN----ADGVADRATFIV
TH_1778|M.thermoresistible__bu      EDLKTLP--------FPMASDLKRELSEATGVLN----DEGVADRATFIV
MAB_4408c|M.abscessus_ATCC_199      EDLKTLP--------FPMLSDLKRELAEAAGVLN----ADGVADRATFIV
Mvan_1420|M.vanbaalenii_PYR-1       KEKISYKGMRDVEVTFPLIDDVTMEVARKYGMIMPGE-DTTKAVRAVFVI
Mflv_3603|M.gilvum_PYR-GCK          ADKQNFD--------YPLLSDTEGTVAAQFGVKRGLLGKFMPVKRTTFVI
                                     :             :*:  *    :    *           . *..*::

Mb2454|M.bovis_AF2122/97            DPNNEIQFVSATAGSVGRNVDEVLRVLDALQS----DELCACNWRKGDPT
Rv2428|M.tuberculosis_H37Rv         DPNNEIQFVSATAGSVGRNVDEVLRVLDALQS----DELCACNWRKGDPT
MMAR_2755|M.marinum_M               DPNNEIQFVSATAGSVGRNVDEVLRVLDALQS----DELCACNWRKGDPT
MUL_2999|M.ulcerans_Agy99           DPNNEIQFVSATAGSVGRNVDEVLRVLDALQS----DELCACNWRKGDPT
MAV_2839|M.avium_104                DPNNEIQFVSVTAGSVGRNVEEVLRVLDALQS----DELCACNWRKGDPT
MLBr_02042|M.leprae_Br4923          DPDNDIQFVSVTAGSVGRNVEEVLRVLDALQS----DQLCACNWRKGDPT
MSMEG_4891|M.smegmatis_MC2_155      DPNNEVQFVSVTAGSVGRNVDEVLRVLDALQS----DELCACNWKKGDPT
TH_1778|M.thermoresistible__bu      DPNNEIQFVSVTAGSVGRNVDEVLRVLDALQS----DELCACNWKKGDPT
MAB_4408c|M.abscessus_ATCC_199      DPDNIIQFVSVTAGSVGRNVDEVLRVLDALQS----DELCACNWRKGDPT
Mvan_1420|M.vanbaalenii_PYR-1       DPEGVVRTIIYYPLSTGRNFDELLRVVKALQTADAFDVATPADWRPGDAV
Mflv_3603|M.gilvum_PYR-GCK          DTDRTVLEVIASEFSMDTHADKALEVLRAR--------------------
                                    *.:  :  :     * . : :: *.*: *                     

Mb2454|M.bovis_AF2122/97            LDAGELLKASA-----------------------------------
Rv2428|M.tuberculosis_H37Rv         LDAGELLKASA-----------------------------------
MMAR_2755|M.marinum_M               LDAGELLKASA-----------------------------------
MUL_2999|M.ulcerans_Agy99           LDAGELLKASA-----------------------------------
MAV_2839|M.avium_104                LNATELLKASA-----------------------------------
MLBr_02042|M.leprae_Br4923          LNATELLKTSA-----------------------------------
MSMEG_4891|M.smegmatis_MC2_155      INAGELLAGAV-----------------------------------
TH_1778|M.thermoresistible__bu      INVAEELTKAV-----------------------------------
MAB_4408c|M.abscessus_ATCC_199      INAGELMSAGV-----------------------------------
Mvan_1420|M.vanbaalenii_PYR-1       IVPPAGSCGTAQSRMSGDVVGVECQDWFFCTRELPADEVEARIRRR
Mflv_3603|M.gilvum_PYR-GCK          ----------------------------------------------