For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
AARRIRAARPLAPHGLPGHLVGFVEALRGSGISVGPSETVDAGRVMATLGLGDREVLREGIACAVLRRPD HRDTYDAMFDLWFPAALGARAVITTEDESAGSGGLPPDDVEAMRQLLLDLLANNQDLAGKDERLVEMIAR IVEAYGKYSSSRGPSFSSYQALKAMALDELEGKLLAGLLAPYGDEPTATQEQIAKALAAQKIAQLRRMVD AETKRRTAEQLGREHVQMYGIPQLSENVEFLRASGEQLRQMRRVVAPLARTLATRLAARRRRARAGSIDL RKTLRKSMSTGGVPIDLVLHKPRPARPELVVLCDVSGSVAGFSHFTLLLVHALRQQFSRVRVFAFIDSTD EVTHMFGPESDLAIAIQRITREAGVYARDGHSDYGNAFVSFMQGFPNVLSPRSSLLVLGDGRTNYRNPAT DVLADMVTASRHAHWLNPEPKHLWGSGDSAVPRYQEVITMHECRSAKQLATVIDQLLPV*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv2425c | - | - | 100% (480) | hypothetical protein Rv2425c |
| M. tuberculosis H37Rv | Rv0368c | - | 2e-07 | 28.44% (218) | hypothetical protein Rv0368c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2449c | - | 0.0 | 100.00% (480) | hypothetical protein Mb2449c |
| M. gilvum PYR-GCK | Mflv_2646 | - | 0.0 | 81.97% (477) | VWA containing CoxE family protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1620 | - | 0.0 | 71.07% (477) | hypothetical protein MAB_1620 |
| M. marinum M | MMAR_3751 | - | 0.0 | 91.46% (480) | hypothetical protein MMAR_3751 |
| M. avium 104 | MAV_1749 | - | 0.0 | 89.00% (482) | hypothetical protein MAV_1749 |
| M. smegmatis MC2 155 | MSMEG_4582 | - | 0.0 | 79.38% (485) | hypothetical protein MSMEG_4582 |
| M. thermoresistible (build 8) | TH_0790 | - | 0.0 | 80.83% (480) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_3694 | - | 0.0 | 90.62% (480) | hypothetical protein MUL_3694 |
| M. vanbaalenii PYR-1 | Mvan_3932 | - | 0.0 | 82.81% (477) | VWA containing CoxE family protein |
CLUSTAL 2.0.9 multiple sequence alignment
Rv2425c|M.tuberculosis_H37Rv MAARR-IRAARPLAPHGLPGHLVGFVEALRGSGISVGPSETVDAGRVMAT
Mb2449c|M.bovis_AF2122/97 MAARR-IRAARPLAPHGLPGHLVGFVEALRGSGISVGPSETVDAGRVMAT
MMAR_3751|M.marinum_M MATRR-IRPSYPLAPHGLPGHLVGFVEALRGSGISVGPSETVDAGRVMAA
MUL_3694|M.ulcerans_Agy99 MATRR-IRPSYPLAPHGLPGHLVGFVEALRGSGISVGPSETVDAGRVMAA
MAV_1749|M.avium_104 MATRR-IRPSRPLAPHGLPGHLVGFVEALRGAGISVGPSETVDAGRVMAT
MSMEG_4582|M.smegmatis_MC2_155 MAPRR-VRPPQPLAPHGLPGHLVEFVEALRGQGISVGPSETVDAGRVLTV
TH_0790|M.thermoresistible__bu MAVRR-TRPPQPLAPHGIPGHLVEFIEALRAQGIYVGPSETVDAGRVVSV
Mflv_2646|M.gilvum_PYR-GCK MPPRR-TRPPQPPAPHGIPGHLVEFVEALRKQGIAVGPSETVDAGQVMAT
Mvan_3932|M.vanbaalenii_PYR-1 MPPRR-TRPPQPLAPHGIPGHLVEFVEALRGQGISVGPSETVDAGQVMAT
MAB_1620|M.abscessus_ATCC_1997 MPPRKPPKAVLPLAPHGLPGHLVGFVEALREQGISVGPSETVDAGRVMTV
*. *: :. * ****:***** *:**** ** **********:*::.
Rv2425c|M.tuberculosis_H37Rv LGLGDREVLREGIACAVLRRPDHRDTYDAMFDLWFPAALGARAVITT---
Mb2449c|M.bovis_AF2122/97 LGLGDREVLREGIACAVLRRPDHRDTYDAMFDLWFPAALGARAVITT---
MMAR_3751|M.marinum_M LGFEDREVLREGIACAVLRRPDHRDTYDAMFDLWFPAALGARAVIT----
MUL_3694|M.ulcerans_Agy99 LGFEDREVLREGIACAVLRRPDHRDTYDAMFDLWFPAALGARAVIT----
MAV_1749|M.avium_104 LGLGNREVLREGLACAVLRRPDHRETYDAMFDLWFPAALGARAVVTD---
MSMEG_4582|M.smegmatis_MC2_155 LGLGNREALREGIACAVLRRADHRDTYDALFDLFFPAALGARTVLDDESD
TH_0790|M.thermoresistible__bu LGLGDREVLREGIACAVLRRPDHRDTYDALFDLYFPAALGARTVLDE---
Mflv_2646|M.gilvum_PYR-GCK LGLSDRNVLREGLACAVLRRSDHRETYDALFDLYFPAALGAKTVLDD---
Mvan_3932|M.vanbaalenii_PYR-1 LGLADRDVLREGLACAVLRRSDHRETYDALFDLYFPAALGSRTVLDD---
MAB_1620|M.abscessus_ATCC_1997 LGLQSRSELREGLACAVLRRADHRPTFDVLFDLWFPPALGARFVEVG---
**: .*. ****:*******.*** *:*.:***:**.***:: *
Rv2425c|M.tuberculosis_H37Rv EDESAGSG--GLPPDDVEAMRQLLLDLLANNQDLAGKDERLVEMIARIVE
Mb2449c|M.bovis_AF2122/97 EDESAGSG--GLPPDDVEAMRQLLLDLLANNQDLAGKDERLVEMIARIVE
MMAR_3751|M.marinum_M EEQAGQSE--GLPPDDVEAMRQLLLDLLTDNPDLADMDQRLVGMIARIVE
MUL_3694|M.ulcerans_Agy99 EEQAGQSE--GLPPDDVEAMRQMLLDLLTDNPDLADMDQRLVGMIARIVE
MAV_1749|M.avium_104 EDAGPGSGEDALPPDDVEAMREMLLDLLTENPDLADMDERLVAMIARIVE
MSMEG_4582|M.smegmatis_MC2_155 ADGEGTGKTPQLPPEDIEAMREMLVQMLADNEELANLDDRLATLIAQIVE
TH_0790|M.thermoresistible__bu -DGEPT-DDPGLPAEDIEAMRAALLDLLADNEELANLDERLAMMIAKIVE
Mflv_2646|M.gilvum_PYR-GCK ----DEDGE-GLPPEDIEALRSALVDLLADNEELANIDERLAAMIAQIVE
Mvan_3932|M.vanbaalenii_PYR-1 ----ESDGESGLPPEDIEAMRQALLDMLTDNEELANLDERLAAMIAQIVE
MAB_1620|M.abscessus_ATCC_1997 --------EEGIDIDDIEQVRDELVDLLASDAG----DLPLNSLIAQIVE
: :*:* :* *:::*:.: * * :**:***
Rv2425c|M.tuberculosis_H37Rv AYGKYSSSRGPSFSSYQALKAMALDELEGKLLAGLLAPYGDEP--TATQE
Mb2449c|M.bovis_AF2122/97 AYGKYSSSRGPSFSSYQALKAMALDELEGKLLAGLLAPYGDEP--TATQE
MMAR_3751|M.marinum_M TYGKYNSSRGPSFSSYQALKAMALDELEGKLLAGLLAPYGDEP--TPTQE
MUL_3694|M.ulcerans_Agy99 TYGKYNSSQGPSFSSYQALKAMALDELEGKLLAGLLAPYGDEL--TPTQE
MAV_1749|M.avium_104 AYGKYSSSRGPSFSSYQALKAMALDELEGKLLAGLLAPYGDEP--TPTQE
MSMEG_4582|M.smegmatis_MC2_155 AYGRYTSSRGPSYSSYQALKAMSLDDLEGRLLAGLLAPYGDEP--MPTQE
TH_0790|M.thermoresistible__bu AYGRYNSSRGPSYSSYQALKAMALDDLEGRLLAGLLAPYGDEP--TPSQE
Mflv_2646|M.gilvum_PYR-GCK AYGRYNSSRGPSYSSYQALKAMSLDDLEGRLLAGLLAPYGDEP--TPTQE
Mvan_3932|M.vanbaalenii_PYR-1 AYGRYNSSRGPSYSSYQALKAMSLDDLEGRLLAGLLAPYGDEP--TPTQE
MAB_1620|M.abscessus_ATCC_1997 AYGKYNSTRGTSYSAYQAMKSLSLDQIEAKLLTGLLGGGDEDSPVSPTDQ
:**:*.*::*.*:*:***:*:::**::*.:**:***. .:: .:::
Rv2425c|M.tuberculosis_H37Rv QIAKALAAQKIAQLRRMVDAETKRRTAEQLGREHVQMYGIPQLSENVEFL
Mb2449c|M.bovis_AF2122/97 QIAKALAAQKIAQLRRMVDAETKRRTAEQLGREHVQMYGIPQLSENVEFL
MMAR_3751|M.marinum_M QIAKAIAAQRVSQLRKMVDAETKRRTAEQLGRDHVQMYGIPQLSENVEFL
MUL_3694|M.ulcerans_Agy99 QIAKAIAAQRVSQLRKMVDAETKRRTAEQLGRDHVQMYGIPQLSENVEFL
MAV_1749|M.avium_104 EIAKALAAQRITQLRKLVDAETKRRTAEQLGRDHVQMYGIPQLSENVEFL
MSMEG_4582|M.smegmatis_MC2_155 EIAKALAAQRIAQLRKMVENETKRRTAEQLGRGHVQMYGVPQLSENVEFL
TH_0790|M.thermoresistible__bu QIAKAIAAQRILQLKQMVEAETKRRTAEQLGREHVQMYGVPQLAENVEFL
Mflv_2646|M.gilvum_PYR-GCK QIAKAIAAQRIAQLRKMVEGETKRRTAEQLGRDHVQMYGVPQLSENVEFL
Mvan_3932|M.vanbaalenii_PYR-1 QIAKAVAAQRIAALRKMVESETKRRTAEQLGRDHVQMYGVPQLAENVEFL
MAB_1620|M.abscessus_ATCC_1997 AVAKAIAKERISKVRQLVEAETKRRTAEQLGRERVTAYGVPQLAENVEFL
:***:* ::: ::::*: ************ :* **:***:******
Rv2425c|M.tuberculosis_H37Rv RASGEQLRQMRRVVAPLARTLATRLAARRRRARAGSIDLRKTLRKSMSTG
Mb2449c|M.bovis_AF2122/97 RASGEQLRQMRRVVAPLARTLATRLAARRRRARAGSIDLRKTLRKSMSTG
MMAR_3751|M.marinum_M RASGEQLRQMRRVVAPLARTLATRLAARRRRARAGSIDLRKTLRKSMSTG
MUL_3694|M.ulcerans_Agy99 RASGEQLRQMRRVVAPLARTLATRLAARRRRARAGSIDLRKTLRKSMSTG
MAV_1749|M.avium_104 RASGEQLRQMQRVVAPLARTLATRLAARRRRSRAGTIDLRKTLRKSMSTG
MSMEG_4582|M.smegmatis_MC2_155 RASGEQLRQMRKTVQPLARTLATRLAARRRRARAGEIDLRKTLRKSMSTG
TH_0790|M.thermoresistible__bu RASGEQLRQMQRVVAPLARMLATRLAARRRRARAGEIDLRKTLRRSMSTG
Mflv_2646|M.gilvum_PYR-GCK RASGEQLRQMRRVVGPLARTLATRLAARRRRSRAGEIDLRKTLRKSMSTG
Mvan_3932|M.vanbaalenii_PYR-1 RASGEQLRQMRRVVGPLARTLATRLAARRRRSRAGEIDLRKTLRKSMSTG
MAB_1620|M.abscessus_ATCC_1997 RASGEQLRNMRRVVHPLARMLASRLAARRRRAHTGQIDLRRTLRKSMSTG
********:*::.* **** **:********:::* ****:***:*****
Rv2425c|M.tuberculosis_H37Rv GVPIDLVLHKPRPARPELVVLCDVSGSVAGFSHFTLLLVHALRQQFSRVR
Mb2449c|M.bovis_AF2122/97 GVPIDLVLHKPRPARPELVVLCDVSGSVAGFSHFTLLLVHALRQQFSRVR
MMAR_3751|M.marinum_M GVPIDVVLRKPRPARPELVVLCDVSGSVAGFSHFTLLLVHALRQQFSRVR
MUL_3694|M.ulcerans_Agy99 GVPIDVVLRKPRPARPELVVLCDVSGSVAGFSHFTLLLVHALRRQFSRVR
MAV_1749|M.avium_104 GVPIDVVLAKPRPARPELVVLCDVSGSVAGFSHFTLLLVHALRQQFSRVR
MSMEG_4582|M.smegmatis_MC2_155 GVPIDVVLKKPHPARPELAVLCDVSGSVAGFSHFTLMLVSALRQQFSRVR
TH_0790|M.thermoresistible__bu GVPIDLVLKKPHPARPELAVLCDVSGSVAGFSHFTLMLVHALRQQFSRVR
Mflv_2646|M.gilvum_PYR-GCK GVPIDVVLKKPHPARPELVVLCDVSGSVAGFSHFTLLLVHALRQQFSRVR
Mvan_3932|M.vanbaalenii_PYR-1 GVPIDLVLKKPHPARPELVVLCDVSGSVAGFSHFTLLLVHALRQQFSRVR
MAB_1620|M.abscessus_ATCC_1997 GVPIDVVQKKPRPARPELVVLCDVSGSVAGFSHFTLLLVNALRQQFSRVR
*****:* **:******.*****************:** ***:******
Rv2425c|M.tuberculosis_H37Rv VFAFIDSTDEVTHMFGPESDLAIAIQRITREAGVYARDGHSDYGNAFVSF
Mb2449c|M.bovis_AF2122/97 VFAFIDSTDEVTHMFGPESDLAIAIQRITREAGVYARDGHSDYGNAFVSF
MMAR_3751|M.marinum_M VFAFIDTTDEVTHMFGPDADLAVAIQRITREAGVYSRDGHSDYGNAFVSF
MUL_3694|M.ulcerans_Agy99 VFAFIDTTDEVTHMFGPDADLAVAIQRITREAGVYSRDGHSDYGNAFVSF
MAV_1749|M.avium_104 VFAFIDTTDEVTHMFGPEADLAVAIQRITREAGVYSRDGHSDYGNAFASF
MSMEG_4582|M.smegmatis_MC2_155 VFAFIDTTDEVTDLFGPEADLAVAVQRITREAGVYTRDGHSDYGHAFVSF
TH_0790|M.thermoresistible__bu VFAFIDTTDEVTDLFGPDADLAVAVQRITREAEVFTRDGHSDYGHAFVSF
Mflv_2646|M.gilvum_PYR-GCK VFAFIDTTDEVTELFGPDSDLAVAVQRITREAAVFTRDGHSDYGHAFVSF
Mvan_3932|M.vanbaalenii_PYR-1 VFAFIDTTDEVTELFGPDADLAVAVQRITREAAVYTRDGHSDYGHAFVSF
MAB_1620|M.abscessus_ATCC_1997 VFAFIDTTDEVTHLFTPDTDLAEAIVRITREAQVFTGDGHSDYGHAFKTF
******:*****.:* *::*** *: ****** *:: *******:** :*
Rv2425c|M.tuberculosis_H37Rv MQGFPNVLSPRSSLLVLGDGRTNYRNPATDVLADMVTASRHAHWLNPEPK
Mb2449c|M.bovis_AF2122/97 MQGFPNVLSPRSSLLVLGDGRTNYRNPATDVLADMVTASRHAHWLNPEPK
MMAR_3751|M.marinum_M MQGFPNVLSPRSSLLVLGDGRTNYRNPATDVLADMVTASRHAHWLNPEPQ
MUL_3694|M.ulcerans_Agy99 MQGFPNVLSPRSSLLVLGDGRTNYRNPATDVLADMVTASRHAHWLNPEPQ
MAV_1749|M.avium_104 EQKFPNVLSPRTSLLVLGDGRTNYRNPEVELLSHMVTASRHAHWLNPEPK
MSMEG_4582|M.smegmatis_MC2_155 LDKYPNALSPRSSLLVLGDGRNNYRNPEAELLAHMVAASRHAHWLNPEPR
TH_0790|M.thermoresistible__bu LDKYPNALSPRSSLLILGDGRNNYRNPELELLERMVDASRHAHWLNPEPR
Mflv_2646|M.gilvum_PYR-GCK LDKFPNVLSPRSSLLVLGDGRNNYRNPETDLLAHMVNAARHAHWLNPEPK
Mvan_3932|M.vanbaalenii_PYR-1 LDKFPNVLSPRSSLLVLGDGRNNYRNPEAHLLAHMVNASRHAHWLNPEPR
MAB_1620|M.abscessus_ATCC_1997 VEKFPTVLSPRSALLILGDGRTNYRNPAVEVLSSMVSSSRHAHWLNPEPK
: :*..****::**:*****.***** .:* ** ::**********:
Rv2425c|M.tuberculosis_H37Rv HLWGSGDSAVPRYQEVITMHECRSAKQLATVIDQLLPV
Mb2449c|M.bovis_AF2122/97 HLWGSGDSAVPRYQEVITMHECRSAKQLATVIDQLLPV
MMAR_3751|M.marinum_M HLWGSGDSAVPRYQEVIAMHECRSAKQLATVIDELLPV
MUL_3694|M.ulcerans_Agy99 HLWGSGDSAVPRYQEVIAMHECRSAKQLATVIDELLPV
MAV_1749|M.avium_104 HLWGSGDSAVPRYQQVIPMHECRSAKQLAAVIDQLLPV
MSMEG_4582|M.smegmatis_MC2_155 HLWGSGDSAVPKYQDIIPMHECRSAKQLAAVIDGLLPV
TH_0790|M.thermoresistible__bu HLWGSGDSAVPRYSEVITMHECRSAKQLAAVIDQLLPV
Mflv_2646|M.gilvum_PYR-GCK HLWGSGDSAVPRYQDVITMHECRSAKQLASVIDALLPV
Mvan_3932|M.vanbaalenii_PYR-1 HLWGSGDSAVPRYQDVITMHECRSAKQLASVIDALLPV
MAB_1620|M.abscessus_ATCC_1997 NHWGTGDSAAKRYQDAITMHECRSAKQLAAVIDNLLPV
: **:****. :*.: *.***********:*** ****