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SHVTAAPNVLAASAGELAAIGSTMRAANAAAAAPTAGVLAAGGDDVSAGIAALFGARAQAYQAISAQAAL FHDRFVQILQEGAAAYAMAEAANALPLQKAQGVVSELAQDRTGGTGTGQSRGAGGFGGVGQAGGKGWDGG PIGNGQVGEQHGAGQLGSTDGNPGVAGAAHGSGVSASHGSGATGAAGVADPGGSGAGVGSAAGNGTGAGS ADAVGGAGTGRDIVGSVRGDGGVGMASGDGGLSTGAAGASAEGGLMPGFGGAPWVGGHWGLGGEGHSGAI GGVGEQVAPAVATAPAVSPATTSAVAAESGSTPATKAQAMHATTNPGNAAHQGNPADPGNSARRADGGRD EQLLLLPLTSLRGLRHTLKKLSGLRARNGLLTASGDNASGSGRPWDRDQLLRALGLRPPGHE*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv2340c | PE_PGRS39 | - | 100% (413) | PE-PGRS FAMILY PROTEIN |
| M. tuberculosis H37Rv | Rv0872c | PE_PGRS15 | 8e-58 | 40.99% (383) | PE-PGRS family protein |
| M. tuberculosis H37Rv | Rv0124 | PE_PGRS2 | 1e-55 | 39.53% (387) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2369c | PE_PGRS39 | 0.0 | 100.00% (413) | PE-PGRS family protein |
| M. gilvum PYR-GCK | Mflv_5091 | - | 7e-30 | 32.03% (359) | triple helix repeat-containing collagen |
| M. leprae Br4923 | MLBr_01183 | - | 6e-10 | 36.26% (91) | hypothetical protein MLBr_01183 |
| M. abscessus ATCC 19977 | MAB_4284c | - | 2e-18 | 28.06% (360) | hypothetical protein MAB_4284c |
| M. marinum M | MMAR_3550 | - | 1e-86 | 48.62% (434) | PE-PGRS family protein, PE_PGRS39 |
| M. avium 104 | MAV_1346 | - | 9e-21 | 33.81% (278) | PE family protein |
| M. smegmatis MC2 155 | MSMEG_0868 | - | 7e-20 | 33.93% (280) | hypothetical protein MSMEG_0868 |
| M. thermoresistible (build 8) | TH_3810 | - | 1e-13 | 30.25% (238) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_2783 | - | 3e-86 | 48.39% (434) | PE-PGRS family protein |
| M. vanbaalenii PYR-1 | Mvan_1264 | - | 4e-28 | 31.25% (288) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
TH_3810|M.thermoresistible__bu --------------------------------------------------
Rv2340c|M.tuberculosis_H37Rv --------------------------------------------------
Mb2369c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_3550|M.marinum_M --------------------------------------------------
MUL_2783|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 -------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP--
MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
TH_3810|M.thermoresistible__bu --------------------------------------------------
Rv2340c|M.tuberculosis_H37Rv --------------------------------------------------
Mb2369c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_3550|M.marinum_M --------------------------------------------------
MUL_2783|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------MVTFGGGATPTP
Mvan_1264|M.vanbaalenii_PYR-1 ------------------------------------WYVVSFGGSGAPTP
MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
TH_3810|M.thermoresistible__bu --------------------------------------------------
Rv2340c|M.tuberculosis_H37Rv --------------------------------------------------
Mb2369c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_3550|M.marinum_M --------------------------------------------------
MUL_2783|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK ----------------------------------------TSLGAAAVDL
Mvan_1264|M.vanbaalenii_PYR-1 ----------------------------------------NNLAASLVDL
MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
TH_3810|M.thermoresistible__bu --------------------------------------------------
Rv2340c|M.tuberculosis_H37Rv --------------------------------------------------
Mb2369c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_3550|M.marinum_M --------------------------------------------------
MUL_2783|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK S------------------------GTSCG----------LICNGQDGTG
Mvan_1264|M.vanbaalenii_PYR-1 S------------------------GTSCG----------LICNGQDGTG
MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA
TH_3810|M.thermoresistible__bu --------------------------------------------------
Rv2340c|M.tuberculosis_H37Rv --------------------------------------------------
Mb2369c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_3550|M.marinum_M --------------------------------------------------
MUL_2783|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ---------------------MSIIDFILNLFRDPVEAASYVADPEAALA
Mflv_5091|M.gilvum_PYR-GCK QN-----GGILFGNGGSGWNSDVVG----MDGGNGGNGGLFGGNGGNGGN
Mvan_1264|M.vanbaalenii_PYR-1 QN-----GGILFGNGGSGWNSEIAG----VSGGNGGNAGLFGGNGGNGGN
MSMEG_0868|M.smegmatis_MC2_155 DNPNGGTGGLLFGDGGHGYDGSAAG----LAGGNGGNAGLFG-NGGNGGV
TH_3810|M.thermoresistible__bu --------------------------------------------------
Rv2340c|M.tuberculosis_H37Rv --------------------------------------------------
Mb2369c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_3550|M.marinum_M --------------------------------------------------
MUL_2783|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 NAGLSAVSAAQVGAVMPVVAESVASNYGYQSQWVNTGNPIHDLSGNLQNY
Mflv_5091|M.gilvum_PYR-GCK GLGGGNGGNGGNAGAFALFGNGGNGGNGGVGVVGATGAVG--APGVAGAT
Mvan_1264|M.vanbaalenii_PYR-1 GLGSGDGGNGGDAGLFSLFGRGGNGGNGGVGIAGATGAVG--APGVAGAT
MSMEG_0868|M.smegmatis_MC2_155 GWAGLDGGNGGSGG--LLMGIGGAGGAGGVGADGTSAHVDGGTGGTGGTG
TH_3810|M.thermoresistible__bu --VDGDGGSGGRTGLFSKLSRGGDGGDGGLG-------------GNGGHG
Rv2340c|M.tuberculosis_H37Rv ----MS-HVTAAPNVLAASAGELAAIGSTMRAANAAAAAPTAGVLAAGGD
Mb2369c|M.bovis_AF2122/97 ----MS-HVTAAPNVLAASAGELAAIGSTMRAANAAAAAPTAGVLAAGGD
MMAR_3550|M.marinum_M ----MP-HVTTSPNLLAATAGDLAAIASTMRQASAAAAAPTAAVQPAGGD
MUL_2783|M.ulcerans_Agy99 ----MP-HVTTSPNLLAATAGDLAAIASTMRQASAAAAAPTAAVQPAGGD
MLBr_01183|M.leprae_Br4923 ----MPLFLNAEPQALTAAANTLEGLSAATVASNAAAAQLTTEIAPPAAD
MAV_1346|M.avium_104 ----MS-FVTTRPEALLAVASMLEGLGSSMDAQNAAAAAPTTSIAPAAAD
MAB_4284c|M.abscessus_ATCC_199 YAAQPDGPSILSPSLLSPRDNDFLSHNDTDFASHNPIASGNQVMSPSGNV
. .
Mflv_5091|M.gilvum_PYR-GCK GATGVTSGVVGGNGEDAVGYGATGAAGAAGAAGAAGAAG-----------
Mvan_1264|M.vanbaalenii_PYR-1 GATGVTSNVTGGNGADAVGYGATGAAGAAGAAGAAGKAG-----------
MSMEG_0868|M.smegmatis_MC2_155 GGTGGTGGIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYVLIAG
TH_3810|M.thermoresistible__bu GGTGIIS--------------------LLSLAGNGGNGG-----------
Rv2340c|M.tuberculosis_H37Rv DVSAGIAALFGARAQAYQAISAQAALFHDRFVQILQEGAA----------
Mb2369c|M.bovis_AF2122/97 DVSAGIAALFGARAQAYQAISAQAALFHDRFVQILQEGAA----------
MMAR_3550|M.marinum_M IVSAGIASLFGAHAYNYQVLSAKAAEFHDRFVEILQTSAQ----------
MUL_2783|M.ulcerans_Agy99 VVSAGIASLFGAHAYNYQVLSAKAAEFHDRFVEILQTSAQ----------
MLBr_01183|M.leprae_Br4923 DVSILLAHFFSGHGRQYQAHASQGATNHQDLIQSLLTSSS----------
MAV_1346|M.avium_104 EVSALQAAQFSAYGTWYQQVSAQAKAIHQTLVQNLDTNAD----------
MAB_4284c|M.abscessus_ATCC_199 DSFNRGPLLDLSFGDLQFGNRDTTAIGDGAVAVGGSNSGP----------
.
Mflv_5091|M.gilvum_PYR-GCK ---AVGSAGAAGEAGETGTWG--NAGLPGKAGDAGGAG------------
Mvan_1264|M.vanbaalenii_PYR-1 ---AVGSAGTAGSAGAPGVWG--NAGLPGAAGAAGGAG------------
MSMEG_0868|M.smegmatis_MC2_155 PNVTVGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGANGGT
TH_3810|M.thermoresistible__bu ----NGYRTTDNNALDGGHGG-----------------------------
Rv2340c|M.tuberculosis_H37Rv ---AYAMAEAANALPLQKAQGVVSELAQDRTGGTGTGQ------------
Mb2369c|M.bovis_AF2122/97 ---AYAMAEAANALPLQKAQGVVSELAQDRTGGTGTGQ------------
MMAR_3550|M.marinum_M ---AYGSTEATNASPLEKAIGVFTAPAEGQAGGPGTGNGAI---------
MUL_2783|M.ulcerans_Agy99 ---AYGSTEATNASPLEKAIGVFTAPAEGQAGGPGTGNGAI---------
MLBr_01183|M.leprae_Br4923 ---AYAGTETAN--------------------------------------
MAV_1346|M.avium_104 ---SYGATEAANRVNTSAAA------------------------------
MAB_4284c|M.abscessus_ATCC_199 IASGQGSTAVNGDVRDSNIINADHGSNVGVDQSQTRVGGDYTN-------
. .
Mflv_5091|M.gilvum_PYR-GCK ----AVGAAGAAG------TVGTAGATGGTG---------------TGAN
Mvan_1264|M.vanbaalenii_PYR-1 ----AIGTAGVAG------AAGTAGATGGTG---------------VGGN
MSMEG_0868|M.smegmatis_MC2_155 VDGHAIGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTAEGTATGGD
TH_3810|M.thermoresistible__bu ----------------------------------------------NGGN
Rv2340c|M.tuberculosis_H37Rv --------------------------------------------------
Mb2369c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_3550|M.marinum_M --------------------------------------------------
MUL_2783|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK GGAGGVGGVGGTGAAG--------------AAGGAGGLGETGTTGGAGGV
Mvan_1264|M.vanbaalenii_PYR-1 GGAGQAGGIGGTGAAG--------------AAGQAGTAGETGVTGGVGGI
MSMEG_0868|M.smegmatis_MC2_155 GGHSTGTGIGGNGGIGSVYAYGNNGAVSGTATGGRGGDGIDGGTGGAGGM
TH_3810|M.thermoresistible__bu VGFFSLFNLGG--------------------AGGWGGSGVDG--------
Rv2340c|M.tuberculosis_H37Rv --------------------------------------------------
Mb2369c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_3550|M.marinum_M --------------------------------------------------
MUL_2783|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK GGQ--GTAGGTGGVGGIGGAGSTGAVGGVGGKG----IQGGQG-------
Mvan_1264|M.vanbaalenii_PYR-1 GGQ--GTEGGTGGVGGVGGVGATGGAGGVGGKG----IQGGQG-------
MSMEG_0868|M.smegmatis_MC2_155 GEIYSGADGEATGISAGGDGGSATGADSLGGRGGTSWVQAGYGPTTGGKA
TH_3810|M.thermoresistible__bu -------------VDVVGGNP-----------------------------
Rv2340c|M.tuberculosis_H37Rv --------------------------------------------------
Mb2369c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_3550|M.marinum_M --------------------------------------------------
MUL_2783|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK ------LQGGKGGDGGAGGKGGDADSMGS------------------AGA
Mvan_1264|M.vanbaalenii_PYR-1 ------LQGGQGGDGGTGGTGGDATSMGE------------------AGA
MSMEG_0868|M.smegmatis_MC2_155 SGTAKAGHGGKASDGGKGGNGGDALVMAAGATGVATGNTAIGGNGGAASA
TH_3810|M.thermoresistible__bu -------------DGGTPG------------------------------A
Rv2340c|M.tuberculosis_H37Rv -----------------------------------------------SRG
Mb2369c|M.bovis_AF2122/97 -----------------------------------------------SRG
MMAR_3550|M.marinum_M -------------------------------------------GGGLHGG
MUL_2783|M.ulcerans_Agy99 -------------------------------------------GGGLHGG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 -----------------------------------------------VSG
Mflv_5091|M.gilvum_PYR-GCK TGGKGGNGGNGGRGGLFG---------------KGGNAGNGAD-------
Mvan_1264|M.vanbaalenii_PYR-1 TGGKGGNGGNGGRGSLFG---------------RGGNAGNGGN-------
MSMEG_0868|M.smegmatis_MC2_155 NGAVGGNGGFTNIAAIHGSITDSSATSGHGGAAQGGNGGNGGNGWVQAYD
TH_3810|M.thermoresistible__bu HGESHTPGVYTDRQ------------------------------------
Rv2340c|M.tuberculosis_H37Rv AGGFGGVGQAGGKGWDGG--------------------------------
Mb2369c|M.bovis_AF2122/97 AGGFGGVGQAGGKGWDGG--------------------------------
MMAR_3550|M.marinum_M AGGFGDVGQPTANAAPVG--------------------------------
MUL_2783|M.ulcerans_Agy99 AGGFGDVGQPTANAAPVG--------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 -----LQGLAPNVIPNAA--------------------------------
MAB_4284c|M.abscessus_ATCC_199 HGSADIDKSVTVVDDHSQR-------------------------------
Mflv_5091|M.gilvum_PYR-GCK ---------------GGTGGAGGAGGTGG-TGGAGGTGG-----------
Mvan_1264|M.vanbaalenii_PYR-1 ---------------GGTGGNGGNGGTGG-TGGNGGTGG-----------
MSMEG_0868|M.smegmatis_MC2_155 PNGPAGTTIDKGKAAGGNGGDGGFNGTGGATGGRGGDGAGASVWKANGQH
TH_3810|M.thermoresistible__bu -------------------GEDGEDGTGTGIGGRGGNGG-----------
Rv2340c|M.tuberculosis_H37Rv ---------------------PIGNGQVGEQHGAGQLGS-----------
Mb2369c|M.bovis_AF2122/97 ---------------------PIGNGQVGEQHGAGQLGS-----------
MMAR_3550|M.marinum_M ---------------------PAGATAAAGTGGSPAQAT-----------
MUL_2783|M.ulcerans_Agy99 ---------------------PAGATAAAGTGGSPAQAT-----------
MLBr_01183|M.leprae_Br4923 ------------------------------HDSL----------------
MAV_1346|M.avium_104 ---------------------PAADPPPAGTTSLGTSIG-----------
MAB_4284c|M.abscessus_ATCC_199 ---------------NTTNINDSFNTDRSTNIGSGNTTN-----------
.
Mflv_5091|M.gilvum_PYR-GCK ------TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGTGGT
Mvan_1264|M.vanbaalenii_PYR-1 ------TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGTGGT
MSMEG_0868|M.smegmatis_MC2_155 STGQTDTGGNGGRGGDGGTFVNAGANGNGGAGGAGGVSEGEGGTGGHGGD
TH_3810|M.thermoresistible__bu -----SSSGTHPMAEDG--------EHVKALDGRPGLD---GGNGSHGGN
Rv2340c|M.tuberculosis_H37Rv --------TDGNPGVAG---AAHGSGVSASHGSGATG----AAGVADPGG
Mb2369c|M.bovis_AF2122/97 --------TDGNPGVAG---AAHGSGVSASHGSGATG----AAGVADPGG
MMAR_3550|M.marinum_M --------VHSGPAAGNGDAASVGTGVQHGGAGGGSGDGMASSHVSDGGA
MUL_2783|M.ulcerans_Agy99 --------VHSGPAAGNGDAASVGTGVQHGGAGGGSGDGMASSHVSDGGA
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------WAQNVGAAASDFITLGEGQFAPVPGAAGIPNFNPGLTAATTA
MAB_4284c|M.abscessus_ATCC_199 -----TEIGSHNQANIGTSTSAGGSAAVGGNAGLAGNAGLAGNAGLAGNA
Mflv_5091|M.gilvum_PYR-GCK GGKGGTGGTGGAGGTG----GDGGTGGTGGTGGTG---------GTGGTG
Mvan_1264|M.vanbaalenii_PYR-1 GGKGGTGGTGGDGGTG----GTGGTGGTGGTGGTG---------GTGGTG
MSMEG_0868|M.smegmatis_MC2_155 GGRGGDGALGGNGGTGGVGLGNGGKGGNGGNGGNGGTYVDPSHTGAGGNG
TH_3810|M.thermoresistible__bu GGHGGRGGFLGIGGSG-------GWGGHGGNGGD-----------TDADG
Rv2340c|M.tuberculosis_H37Rv SGAG-VGSAAGNGTGAG------SADAVGGAGTGR--------DIVGSVR
Mb2369c|M.bovis_AF2122/97 SGAG-VGSAAGNGTGAG------SADAVGGAGTGR--------DIVGSVR
MMAR_3550|M.marinum_M ARAGGAANSAGGTDAAA------SSSGAGGGGSAG--------QGVASTG
MUL_2783|M.ulcerans_Agy99 ARAGGAANSAGGTDAAA------SSSGAGGGGSAG--------QGVASTG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 GPPAPAAPAAAAGAPVL------ASMGRGPSIGGL--------SVPPSWA
MAB_4284c|M.abscessus_ATCC_199 GLAGNAGLAGNAGLAGN-----AGLAGNAGLAGNAG------LAGNAGLA
Mflv_5091|M.gilvum_PYR-GCK GTGGAG-----------DGTGGTGGTGG----TGGQGGQGGQGG------
Mvan_1264|M.vanbaalenii_PYR-1 GTGGAG-----------DGLGGTGGTGG----TGGFGGQGGQGG------
MSMEG_0868|M.smegmatis_MC2_155 GNGGAGRIRVNNGTATGTATGGNGGNGGNGDADGHRGGKGGDGGEALIRA
TH_3810|M.thermoresistible__bu GNGGDG---------------GNGGSAG----------------------
Rv2340c|M.tuberculosis_H37Rv GDGGVG-----------MASGDGGLSTG----------------------
Mb2369c|M.bovis_AF2122/97 GDGGVG-----------MASGDGGLSTG----------------------
MMAR_3550|M.marinum_M GDHGAG-----------ATSSASGHSPG----------------------
MUL_2783|M.ulcerans_Agy99 GDHGAG-----------ATSSASGHSPG----------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 PGGVAP-----------AANATPAQLVG----------------------
MAB_4284c|M.abscessus_ATCC_199 GNAGLAG---------NAGLAGNAGLAG----------------------
Mflv_5091|M.gilvum_PYR-GCK -----------TGGTGGQGG-LGGGGGTG---------------------
Mvan_1264|M.vanbaalenii_PYR-1 -----------TGGTGGQGG-LGGVGGTG---------------------
MSMEG_0868|M.smegmatis_MC2_155 TVIGSNASGTATGGDGGNGGTLGATNGTGGAATIVAYNVVQANPQASGTA
TH_3810|M.thermoresistible__bu -----------RGGTGGLRGVFGINGGNG---------------------
Rv2340c|M.tuberculosis_H37Rv ------AAG--ASAEGGLMPGFGGAPWVG---------------------
Mb2369c|M.bovis_AF2122/97 ------AAG--ASAEGGLMPGFGGAPWVG---------------------
MMAR_3550|M.marinum_M ------HGVGLGSGLGRSLDGYGTAALAG---------------------
MUL_2783|M.ulcerans_Agy99 ------HGVGLGSGLGRSLDGYGTAALAG---------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 ------AGFTSAAPDTAPVTAVPGGVPSM---------------------
MAB_4284c|M.abscessus_ATCC_199 -----NAGLAGNAGLAGNAGLAGNAGLAG---------------------
Mflv_5091|M.gilvum_PYR-GCK --GQGGTGGTGGQGGTGGTGGTGGTG--------GTGGAGGDGGLGGLGG
Mvan_1264|M.vanbaalenii_PYR-1 --GTGGTGGTGGQGGTGGTGGTGGTG--------GTGGAGGDGGLGGLGG
MSMEG_0868|M.smegmatis_MC2_155 TDGHGGSGINGGHGGNGGQGTIEANGPSAVASGIGAGGNGGDGIDGGLGG
TH_3810|M.thermoresistible__bu ---RAGLGGRGXXXXGGGVGAAVRSG---------------NGVFSGGGG
Rv2340c|M.tuberculosis_H37Rv --GHWGLGGEGHSGAIGGVGEQVAPAVATAPAVSPATTSAVAAESGSTPA
Mb2369c|M.bovis_AF2122/97 --GHWGLGGEGHSGAIGGVGEQVAPAVATAPAVSPATTSAVAAESGSTPA
MMAR_3550|M.marinum_M --GPLGAVGSGAPGAVGGVGELSAPTATSALPTAASAT----AEPSLAMS
MUL_2783|M.ulcerans_Agy99 --GPLGAVGSGAPGAVGGVGELLAPTATSALPTAASAT----AEPSLAMS
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --ATAGRGGYGLGAPRYGVKPTVMPKPAI---------------------
MAB_4284c|M.abscessus_ATCC_199 --NAGLAGNAGLAGNAGLAGNAGLAGNAAVAGNAAVAGNAAVAGNAAVGG
Mflv_5091|M.gilvum_PYR-GCK FGGSGGTGGQGGLGGPGGSTGGAGGAGG--QAGTAGKGGLFG----GSGS
Mvan_1264|M.vanbaalenii_PYR-1 FGGVGGTGGQGGQGGPGGSTGGAGGAGG--QAGVAGKGGLFG----GSGS
MSMEG_0868|M.smegmatis_MC2_155 NGGDGVVNTTANAANPGSATGTATGGDGGKATGTASQGGNGGPSWVQSGY
TH_3810|M.thermoresistible__bu TPSAGFGVPTTIQFPAGSCTSRAVSREG----------------------
Rv2340c|M.tuberculosis_H37Rv TKAQAMHATT--NPGNAAHQGNPADPGNSARRADGGRDEQLLLLPLTSLR
Mb2369c|M.bovis_AF2122/97 TKAQAMHATT--NPGNAAHQGNPADPGNSARRADGGRDEQLLLLPLTSLR
MMAR_3550|M.marinum_M TKAQLVHATNPLQPVNPAHSDSSANQGGPARRTGVERDGPTLFLPLTSLR
MUL_2783|M.ulcerans_Agy99 TKAQLVRATNPLQPVNPAHSDSSANQGGPARRTGVERDGPTLFLPLTSLR
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 VLNTGVSGAIGGSSHVGGAINESLGGSGSVGGSTAVGGGAHTGVGGGVST
Mflv_5091|M.gilvum_PYR-GCK AGKAGATGAAGASGGKGAQGATGAQGATG------AQGATG-ATGAAGKA
Mvan_1264|M.vanbaalenii_PYR-1 AGTAGVTGASGASGGKGAQGATGAQGATG------AQGATG-ATGASGAQ
MSMEG_0868|M.smegmatis_MC2_155 GSTLGGNATGTATAGKGGEASNGGVAGNGGNALVMAAGTTGVATGNTATG
TH_3810|M.thermoresistible__bu --IMPSSRAASARAG---------------------------AACASSTS
Rv2340c|M.tuberculosis_H37Rv GLRHTLKKLSGLRARNGLLTASGDNASGSGRPWDRDQLLRALGLRPPGHE
Mb2369c|M.bovis_AF2122/97 GLRHTLKKLSGLRARNGLLTASGDNASGSGRPWDRDQLLRALGLRPPGHE
MMAR_3550|M.marinum_M GLRRHSKKRSGLRAQSGRLRDSGDAVS-SPR-WEPDDLLRALGLRPPGHQ
MUL_2783|M.ulcerans_Agy99 GLRRHSKKRSGLRAQSGRLRDSGDAVS-SPR-WEPDDLLRALGLRPPGHQ
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 GVGVGSHVGGGISESLGGSGSVGGSTAVGGGAHTGVGGGVSTGVGVGSHV
Mflv_5091|M.gilvum_PYR-GCK GATGAAGAAGAAGSAG-----------TTGAQGSAGTNGA-NGANGSQGA
Mvan_1264|M.vanbaalenii_PYR-1 GSAGSAGSAGVAGSAG-----------TTGAQGSAGTNGA-NGANGSQGA
MSMEG_0868|M.smegmatis_MC2_155 GDGGAATTAGATGGAGGFSNIAAIHGAITDSTAISGHGGAGNGGNGGKGA
TH_3810|M.thermoresistible__bu RSRRSFCCSRA---------------------------------------
Rv2340c|M.tuberculosis_H37Rv --------------------------------------------------
Mb2369c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_3550|M.marinum_M --------------------------------------------------
MUL_2783|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 GGGISESLGGSGSVG------------GSTAVGGGAHTGVGGGVNTGVGV
Mflv_5091|M.gilvum_PYR-GCK AGKAGATGTTGATG--------AAGEDGDAGSGGSG-INGGAGGAGG---
Mvan_1264|M.vanbaalenii_PYR-1 AGKAGATGTTGATG--------AAGDAGDPGSEAVD-INGGAGGAGG---
MSMEG_0868|M.smegmatis_MC2_155 DGWVQAYDPAGPVGSKIANSSAVAGNGGDGGVNGTGGASGGDGGNGGNTS
TH_3810|M.thermoresistible__bu --------------------------------------------------
Rv2340c|M.tuberculosis_H37Rv --------------------------------------------------
Mb2369c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_3550|M.marinum_M --------------------------------------------------
MUL_2783|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 GSHVGGG---------------ISESLGGSGSVGGSTAVGGGAHTSAIND
Mflv_5091|M.gilvum_PYR-GCK --------AGGEGGEGGDGGKGGAGAE--------GGAGGGGGAGGSGAG
Mvan_1264|M.vanbaalenii_PYR-1 --------AGGEGGEGGAGGAGGDGSE--------GGAGGSGGAGGSGTG
MSMEG_0868|M.smegmatis_MC2_155 VWKSGGQTADGEHNTGGNGGNGGDGSEPGPGGNGAGGAGGNGGTGGTTAG
TH_3810|M.thermoresistible__bu --------------------------------------------------
Rv2340c|M.tuberculosis_H37Rv --------------------------------------------------
Mb2369c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_3550|M.marinum_M --------------------------------------------------
MUL_2783|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ALGGSGSVGGSTAVGGGAHTSAINESMNSSINASHSSSMNESFGSSMGSH
Mflv_5091|M.gilvum_PYR-GCK GAG--GAGGSGGSGGSGGSGGSGGAAGDSDD
Mvan_1264|M.vanbaalenii_PYR-1 GAG--GAGGSGGSGGSGGAGGSGGAAGDSD-
MSMEG_0868|M.smegmatis_MC2_155 GSGNGGNGGNGGNGGADGTPGTAGTTGANNP
TH_3810|M.thermoresistible__bu -------------------------------
Rv2340c|M.tuberculosis_H37Rv -------------------------------
Mb2369c|M.bovis_AF2122/97 -------------------------------
MMAR_3550|M.marinum_M -------------------------------
MUL_2783|M.ulcerans_Agy99 -------------------------------
MLBr_01183|M.leprae_Br4923 -------------------------------
MAV_1346|M.avium_104 -------------------------------
MAB_4284c|M.abscessus_ATCC_199 GAAGTGFEAQGHAQGHASETAHTTLPGAEHH