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TNLADATQATMALVERHAAHNYSPLPVVAASAEGAWIADIDGLRYLDWLAAYSAVNLGHRNPASTATAHA QVDTVTLLNRALHADRLGPLGAALAQLCGKDVVLPMNSDAEAVESGLRVARKWGADVNGLPAGRHDIILA NNNFHGHTSSVVSFSSDPAAGSGVEPSTPGLRSVPFGDAAAPAQTIDDNTVADLLEPIPGQAGIIVPADD YLPAASSTTC*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv2322c | rocD1 | - | 100% (221) | PROBABLE ORNITHINE AMINOTRANSFERASE (N-terminus part) ROCD1 (ORNITHINE--OXO-ACID AMINOTRANSFERASE) |
| M. tuberculosis H37Rv | Rv1655 | argD | 4e-24 | 32.88% (222) | acetylornithine aminotransferase |
| M. tuberculosis H37Rv | Rv2589 | gabT | 1e-11 | 27.50% (240) | 4-aminobutyrate aminotransferase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2349c | rocD1 | 1e-126 | 100.00% (221) | ornithine aminotransferase |
| M. gilvum PYR-GCK | Mflv_5071 | - | 5e-76 | 65.42% (214) | ornithine aminotransferase |
| M. leprae Br4923 | MLBr_01409 | argD | 3e-24 | 33.00% (203) | acetylornithine aminotransferase |
| M. abscessus ATCC 19977 | MAB_3841 | - | 6e-75 | 65.84% (202) | ornithine aminotransferase RocD1 |
| M. marinum M | MMAR_3622 | rocD | 4e-85 | 71.77% (209) | ornithine aminotransferase RocD1 and RocD2 |
| M. avium 104 | MAV_2086 | rocD | 7e-84 | 70.62% (211) | ornithine--oxo-acid transaminase |
| M. smegmatis MC2 155 | MSMEG_1413 | rocD | 5e-79 | 66.20% (213) | ornithine--oxo-acid transaminase |
| M. thermoresistible (build 8) | TH_3529 | - | 5e-24 | 32.84% (201) | PUTATIVE aminotransferase |
| M. ulcerans Agy99 | MUL_1243 | rocD | 2e-85 | 71.77% (209) | ornithine aminotransferase RocD1 and RocD2 |
| M. vanbaalenii PYR-1 | Mvan_1287 | - | 4e-78 | 67.63% (207) | ornithine aminotransferase |
CLUSTAL 2.0.9 multiple sequence alignment
Rv2322c|M.tuberculosis_H37Rv MTN---------------LADATQATMALVERHAAHNYSPLPVVAASAEG
Mb2349c|M.bovis_AF2122/97 MTN---------------LADATQATMALVERHAAHNYSPLPVVAASAEG
Mflv_5071|M.gilvum_PYR-GCK MTA---------------VHASTDALIAAEARHVAHNYSPLPVVAASAQG
Mvan_1287|M.vanbaalenii_PYR-1 MTVG--------------IMGNTEATIELDHRHVAHNYAPLPVVAASAEG
MSMEG_1413|M.smegmatis_MC2_155 MTILDNVNHGLDPHDAGAAATSIAEAIALDDRYVAHNYSPLPVVAASAEG
MAB_3841|M.abscessus_ATCC_1997 MTVTEAPG-------MSPDSYKSAEYIELAEQYGAHNYAPLPVVAHRAEG
MMAR_3622|M.marinum_M MTILDAP--------VSVEVDETGDAIALVEKHAAHNYSPLPVVAASAEG
MUL_1243|M.ulcerans_Agy99 MTILDAP--------VSVGVDETGDAIALVEKHAAHNYSPLPVVAASAEG
MAV_2086|M.avium_104 MTILDGQ--------LTATRVDS--AIRLAEKRAAHNYSPLPIVAASAQG
MLBr_01409|M.leprae_Br4923 ---------------MTPTQTNTATMQQRWETVMMNNYGTPPIVLASGNG
TH_3529|M.thermoresistible__bu ----------------VSGSKGRHTLLDRWQGVMMNNYGTPPLALVSGDG
:**.. *:. .:*
Rv2322c|M.tuberculosis_H37Rv AWIADIDGLRYLDWLAAYSAVNLGHRNPASTATAHAQVDTVTLLNRALHA
Mb2349c|M.bovis_AF2122/97 AWIADIDGLRYLDWLAAYSAVNLGHRNPASTATAHAQVDTVTLLNRALHA
Mflv_5071|M.gilvum_PYR-GCK AWITDVEGRRHLDCLAAYSAVNFGHRNPEIIAAAHAQLDAVTLVSRAFHS
Mvan_1287|M.vanbaalenii_PYR-1 AWITDVEGRRYLDCLAAYSAVNFGHRNPEVIATAHAQLDAVTLVSRAFHS
MSMEG_1413|M.smegmatis_MC2_155 VWITDVTGRRYLDCLAAYSAVNFGHRNPEIVATAHAQLDRLTLVSRAFHS
MAB_3841|M.abscessus_ATCC_1997 AWIEDVDGKRYLDCLAAYSAVNFGHGNPEILATSHAQLDTVTLVSRAFHS
MMAR_3622|M.marinum_M AWITDVEGRRYLDCLSAYSAVNFGHCNPEIIATAHAQLDTVTLVSRAFHS
MUL_1243|M.ulcerans_Agy99 AWITDVEGRRYLDCLSAYSAVNFGHCNPEIIATAHAQLDTVTLVSRAFHS
MAV_2086|M.avium_104 AWITDVDGRRYLDCLSAYSAVNFGHRHPEIVATAHAQLDTVTLVSRAVHS
MLBr_01409|M.leprae_Br4923 AVVTDVDSNTYLDLLGGIAVNVLGHRHPAVIEAVTHQITTLGHTSNLYAT
TH_3529|M.thermoresistible__bu AVVTDADGKSYLDLLGGIAVNILGHRHPAVIEAVTRQLNTLGHTSNLYAT
. : * . :** *.. :. :** :* : *: : .. :
Rv2322c|M.tuberculosis_H37Rv DRLGPLGAALAQLCGKD---VVLPMNSDAEAVESGLRVARKWGADVNGLP
Mb2349c|M.bovis_AF2122/97 DRLGPLGAALAQLCGKD---VVLPMNSDAEAVESGLRVARKWGADVNGLP
Mflv_5071|M.gilvum_PYR-GCK DQLGPFAEALAGLCGKD---MVLPMNSGAEAVESGIKVARKWGTDVKGVS
Mvan_1287|M.vanbaalenii_PYR-1 DRLAPFCAALADLCGKD---MVLPMNSGAEAVESGIKVARKWGVDVKGVK
MSMEG_1413|M.smegmatis_MC2_155 DQLGPFAQALATLCGKD---MILPMNSGAEAVESGIKVARKWGTDVKGVA
MAB_3841|M.abscessus_ATCC_1997 DRLGRFCRDLARLCGKG---MVLPMNTGAEAVESGIKVARKWGTDVKGVP
MMAR_3622|M.marinum_M DRLGPFCAALSELCGKD---MVLPMNSGAEAVESGLKVARKWGADVKGVP
MUL_1243|M.ulcerans_Agy99 DRLGPFCAALSELCGKD---MVLPMNSGAEAVESGLKVARKWGADVKGVP
MAV_2086|M.avium_104 DKLGPFCAALAYLCDKD---MVLPMNSGAEAVESGLKVARKWGAEVKGVP
MLBr_01409|M.leprae_Br4923 EPSITLAEELVALLGADTQTRVFFCNSGTEANELAFKLSRLTG-------
TH_3529|M.thermoresistible__bu EPGVALAEALVGHLGAP--ARVFFCNSGAEANEVAFKISRLTG-------
: : * . :: *:.:** * .::::* *
Rv2322c|M.tuberculosis_H37Rv AGRHDIILANNNFHGHTSSVVSFSSDPAAGSGVEPSTPGLRSVPFGDAAA
Mb2349c|M.bovis_AF2122/97 AGRHDIILANNNFHGHTSSVVSFSSDPAAGSGVEPSTPGLRSVPFGDAAA
Mflv_5071|M.gilvum_PYR-GCK D--STIIVARNNFHGRTTTIISFSDDDTARRGFGPYTPGFRSVPFGDADA
Mvan_1287|M.vanbaalenii_PYR-1 T--PNIVVAHNNFHGRTTTIISFSDDETARRGFGPYTPGFRSVPFGDADA
MSMEG_1413|M.smegmatis_MC2_155 AGQSNIVVARNNFHGRTTTIISFSDDETARRGFGPYTPGFRSVPFGDAAA
MAB_3841|M.abscessus_ATCC_1997 VDQANIVVAHNNFHGRTISIVSFSSDETARGGFGPFTPGFRIVPFGDAAA
MMAR_3622|M.marinum_M EGQANIVVADNNFHGRTISIVSFSSDPVARGGFGPFTPGFRSVPFGDSTA
MUL_1243|M.ulcerans_Agy99 EGQANIVVADNNFHGRTISIVSFSSDPVARGGFGPFTPGFRSVPFGDSTA
MAV_2086|M.avium_104 AGQANIIVADNNFHGRTISIVSFSSDAAARDGFGPFTPGFRSVPFGDAGA
MLBr_01409|M.leprae_Br4923 --RTKLVAAQAAFHGRTMGSLALTGQPAKQAAFEPLPGHVTHVPYGQVDA
TH_3529|M.thermoresistible__bu --RTKVVAAEGGFHGRTMGALALTGQPSKREPFEPLPGDVIHVPYGDAGA
:: * ***:* ::::.: . * . . **:*: *
Rv2322c|M.tuberculosis_H37Rv PAQTIDDNTVADLLEPIPGQAGIIVPADDYLPAASSTTC-----------
Mb2349c|M.bovis_AF2122/97 PAQTIDDNTVADLLEPIPGQAGIIVPADDYLPAASSTTC-----------
Mflv_5071|M.gilvum_PYR-GCK LEQAIDGNTVAVLLEPIQGEAGIIVPPDDYLPRVRALCTEHDVLMIADEI
Mvan_1287|M.vanbaalenii_PYR-1 LAPAVDDDTVAVLIEPIQGEAGIIVPPDDYLPRVRALCTERNVLMIADEI
MSMEG_1413|M.smegmatis_MC2_155 VADAIDDNTVAVLLEPIQGEAGIIVPPPDFLPRVREICTQRNVLMIADEI
MAB_3841|M.abscessus_ATCC_1997 LERAIDGNTVAVLLEPVQGEAGIVIPPDDYLPAVRALCTENNVLFIADEI
MMAR_3622|M.marinum_M LARAIDENTVAVLLEPIQGEAGIVVPPDDYLPDVRALCSEHNVLMIADEI
MUL_1243|M.ulcerans_Agy99 LARAIDENTVAVLLEPIQGEAGIVVPPDDYLPDVRALCSEHNVLMIADEI
MAV_2086|M.avium_104 LAQAIDDNTVAVLLEPIQGEAGIVVPPDDYLPAVRALCSEHNVLMIADEI
MLBr_01409|M.leprae_Br4923 LAAAVDNDTAAVFLEPIMGESGVIVPPEGYLAAARDITTRHGALLVIDEV
TH_3529|M.thermoresistible__bu LERAVDDTTAAVFLEPIMGEGGVVVPPAGYLAAAREVTARHGALLVLDEV
::* *.* ::**: *:.*:::*. .:*. .
Rv2322c|M.tuberculosis_H37Rv --------------------------------------------------
Mb2349c|M.bovis_AF2122/97 --------------------------------------------------
Mflv_5071|M.gilvum_PYR-GCK QSGLARTGRTFACDHWGVVPDVYLLGKALGGGVVPLSAVVADRDVLGVLH
Mvan_1287|M.vanbaalenii_PYR-1 QSGLARTGRTFACDHWGVVPDIYLLGKALGGGVLPLSAVVADRDILGVLH
MSMEG_1413|M.smegmatis_MC2_155 QSGLARTGRTFACEHWGVVPDVYLLGKALGGGVVPLSAVVADRDVLGVLH
MAB_3841|M.abscessus_ATCC_1997 QAGLARTGRMFACDHWNVVPDVYLLGKALGGGVVPVSAVVADADVLGVLH
MMAR_3622|M.marinum_M QSGLGRTGYTFACDYWDVVPDVFLLGKALGGGVVPLSAVVADRDVLGVLN
MUL_1243|M.ulcerans_Agy99 QSGLGRTGYTFACDYWDVVPDVFLLGKALGGGVVPLSAVVADRDVLGVLN
MAV_2086|M.avium_104 QSGLARTGYTFACDRWRVVPDVYLLGKALGGGVVPLSAVVADREILGVLH
MLBr_01409|M.leprae_Br4923 QTGIGRTGAFFAHQHDSITPDVVTLAKGLGGG-LPIGAFLATGPAAELLT
TH_3529|M.thermoresistible__bu QTGIGRTGTFFAHQHDGITPDVVTLAKGLGGG-LPIGACLAVGPAGDLLT
Rv2322c|M.tuberculosis_H37Rv --------------------------------------------------
Mb2349c|M.bovis_AF2122/97 --------------------------------------------------
Mflv_5071|M.gilvum_PYR-GCK PGEHGSTFGGNPLAAAIGRTVVDILERGEFQQRATELGAHLQARLSTLTG
Mvan_1287|M.vanbaalenii_PYR-1 PGEHGSTFGGNPLAAAIGSTVVDILRRGEFQRRSTELGAHLHARLNGLKG
MSMEG_1413|M.smegmatis_MC2_155 PGEHGSTFGGNPLATAIGSTVVAMLRRGEFQQRSTELGAHLHARLQDLIG
MAB_3841|M.abscessus_ATCC_1997 PGEHGSTFGGNPLGAAIGSTVVAILERGEFQRRASVLGRHLRTRLDALIG
MMAR_3622|M.marinum_M PGEHGSTFGGNPLAAAIGTTVVSMLERGEFQSRSAELGARLHARLGALIG
MUL_1243|M.ulcerans_Agy99 PGEHGSTFGGNPLAAAIGTTVVSMLERGEFQSRSAELGARLHARLGALIG
MAV_2086|M.avium_104 PGEHGSTFGGNPLAAAIGTTVVSMLARGEYQARATALGAHLQRRLRALVG
MLBr_01409|M.leprae_Br4923 LGLHGSTFGGNPVCTAAALAVLRVLATQGLVRRAEVLGDSMRIGIESLSH
TH_3529|M.thermoresistible__bu PGMHGSTFGGNPVCTAAAVAVLGALAEGDLINRADVLGKKLSHGIEELRH
Rv2322c|M.tuberculosis_H37Rv --------------------------------------------------
Mb2349c|M.bovis_AF2122/97 --------------------------------------------------
Mflv_5071|M.gilvum_PYR-GCK RGVVAVRGKGLWAGVDIDPAHGTGKQISLRLAERGVLVKDTHGSTLRFAP
Mvan_1287|M.vanbaalenii_PYR-1 RGVLAVRGRGLWAGVDIDPAHGTGKQVSLRLAERGVLVKDTHGSTLRFAP
MSMEG_1413|M.smegmatis_MC2_155 RGVLAVRGRGLWAGVDIDPALGTGKELSVALAERGVLVKDTHGSTLRFAP
MAB_3841|M.abscessus_ATCC_1997 HGVTEVRSLGLWAGVDIDPNLATGRQIGLRMAEFGVLVKDTHGATLRFAP
MMAR_3622|M.marinum_M EGVLEVRGLGLWAGVDVDPALATGKEISLRLADRGVLVKDTHGSTLRFAP
MUL_1243|M.ulcerans_Agy99 EGVLEVRGLGLWAGVDVDPALATGKEISLRLADRGVLVKDTHGSTLRFAP
MAV_2086|M.avium_104 HGVDEVRGLGLWAGVDIDPSLGSGRQMSLRLAERGVLVKDTHGATLRFAP
MLBr_01409|M.leprae_Br4923 PLIDQVRGRGLLLGIVLTAPRAKDIEKAAR--DAGFLVNATAPEVIRLAP
TH_3529|M.thermoresistible__bu PLVDHVRGRGLLCGVVLNAPQAKAAEAAAR--DAGFLVNAAAPEVIRLAP
Rv2322c|M.tuberculosis_H37Rv -------------------------------
Mb2349c|M.bovis_AF2122/97 -------------------------------
Mflv_5071|M.gilvum_PYR-GCK PLVITADEIDWAVARLEEVLT----------
Mvan_1287|M.vanbaalenii_PYR-1 PLVITADEIDWAIDRFAEVLGR---------
MSMEG_1413|M.smegmatis_MC2_155 PLVVTSEEIDWAVDRFADTLAEVRR------
MAB_3841|M.abscessus_ATCC_1997 PLVITEGEIDWAVDQFADALASFR-------
MMAR_3622|M.marinum_M PLVITAQEIDWAVRQFAAVLREAGS------
MUL_1243|M.ulcerans_Agy99 PLVITAQEIDWAVRQFAAVLREAGS------
MAV_2086|M.avium_104 PLVVTAQEIDWAVGQLAAVLREAAS------
MLBr_01409|M.leprae_Br4923 PLIITESQIDSFITALPGILDASIAELGKKA
TH_3529|M.thermoresistible__bu PLIITETQIDEFLAALPGVLDTAKEAS----