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MAAIERVITHGTFELDGGSWEVDNNIWLVGDDSEVVVFDAAHHAAPIIDAVGGRKVVAVICTHGHNDHVT VAPELGTALDAPVLMHPGDAVLWRMTHPDKSFRAVSDGDAVRVGGTELRALHTPGHSPGSVCWYAPELGP GTGTVFSGDTLFAGGPGATGRSYSDFPTILRSISGRLGALPGDTVVHTGHGDSTTIGDEIVHYEEWVARG H
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv2260 | - | - | 100% (211) | hypothetical protein Rv2260 |
| M. tuberculosis H37Rv | Rv1637c | - | 1e-23 | 36.55% (197) | hypothetical protein Rv1637c |
| M. tuberculosis H37Rv | Rv2581c | - | 2e-17 | 33.54% (161) | glyoxalase II |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2284 | - | 1e-126 | 100.00% (211) | hypothetical protein Mb2284 |
| M. gilvum PYR-GCK | Mflv_2765 | - | 1e-100 | 78.85% (208) | beta-lactamase domain-containing protein |
| M. leprae Br4923 | MLBr_01391 | - | 1e-21 | 34.17% (199) | hypothetical protein MLBr_01391 |
| M. abscessus ATCC 19977 | MAB_4755c | - | 1e-100 | 80.09% (211) | hypothetical protein MAB_4755c |
| M. marinum M | MMAR_3351 | - | 1e-107 | 86.54% (208) | hypothetical protein MMAR_3351 |
| M. avium 104 | MAV_2180 | - | 1e-107 | 83.41% (211) | metallo-beta-lactamase family protein |
| M. smegmatis MC2 155 | MSMEG_4342 | - | 1e-90 | 71.90% (210) | metallo-beta-lactamase family protein |
| M. thermoresistible (build 8) | TH_1503 | - | 4e-96 | 76.92% (208) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_1291 | - | 1e-106 | 86.83% (205) | hypothetical protein MUL_1291 |
| M. vanbaalenii PYR-1 | Mvan_3768 | - | 1e-102 | 81.25% (208) | beta-lactamase domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2765|M.gilvum_PYR-GCK --------------MNGGPIQRLVTSGTFELDGGSWDVDNNIWIVGD--D
Mvan_3768|M.vanbaalenii_PYR-1 --------------MNGGPIQRLVTSGTFELDGGSWDVDNNIWIVGD--D
TH_1503|M.thermoresistible__bu --------------VNGGPIQRVVTSGKFELDGGSWDVDNNIWIVGD--D
Rv2260|M.tuberculosis_H37Rv --------------MAA--IERVITHGTFELDGGSWEVDNNIWLVGD--D
Mb2284|M.bovis_AF2122/97 --------------MAA--IERVITHGTFELDGGSWEVDNNIWLVGD--D
MMAR_3351|M.marinum_M --------------MVH--IDRVVTHGTFELDGGSWEVDNNIWLVGD--D
MUL_1291|M.ulcerans_Agy99 ----------------------MVTHGTFELDGGSWEVDNNIWLVGD--D
MAV_2180|M.avium_104 -------------MMAG--IDKIVTHGTFELDGGSWEVDNNIWIVGD--D
MAB_4755c|M.abscessus_ATCC_199 --------------MSG--IERVITRGTFELDGGSWEVDNNIWIVGE--G
MSMEG_4342|M.smegmatis_MC2_155 -------------MTGPAQIQRVVTSGTFSLDGGTWDVDNNIWLVGD--D
MLBr_01391|M.leprae_Br4923 MTASIDPVNDYTGHVDPGTAARRALPGATILKVSVGPMDNNAYLVTCSAT
* *. . :*** ::*
Mflv_2765|M.gilvum_PYR-GCK KEVIVFDAAHTADPIIEAVG--GRHVVAVVCTHGHNDHVTVAPQLGEALD
Mvan_3768|M.vanbaalenii_PYR-1 NEVVVFDAAHTADPIIEAVG--GRHVVAVVCTHGHNDHVTVAPQLGQALD
TH_1503|M.thermoresistible__bu KEVIVFDAAHEAAPIKAAVG--DRHVVAVVCTHGHNDHITVAPELGSELD
Rv2260|M.tuberculosis_H37Rv SEVVVFDAAHHAAPIIDAVG--GRKVVAVICTHGHNDHVTVAPELGTALD
Mb2284|M.bovis_AF2122/97 SEVVVFDAAHHAAPIIDAVG--GRKVVAVICTHGHNDHVTVAPELGTALD
MMAR_3351|M.marinum_M SDVVVFDAAHQAAPIIEAVA--GRNVVAVVCTHGHNDHVTVAPELGAALD
MUL_1291|M.ulcerans_Agy99 SDVVVFDAAHQAAPIIEAVA--GRNVVAVVCTHGHNDHVTVAPELGAALD
MAV_2180|M.avium_104 SDVVVFDAAHTAEPIVAAVG--NRNVVAVVCTHGHNDHVTVAPELGAALD
MAB_4755c|M.abscessus_ATCC_199 DDVVVFDAAHSAQPIIDAVG--GRNVVAVVCTHGHNDHITVAPELSQALD
MSMEG_4342|M.smegmatis_MC2_155 NDVIVFDAAHTAAPIVDAVA--GRNVVAVICTHGHNDHITVAPDLAVALD
MLBr_01391|M.leprae_Br4923 GETLLIDAANDAEVLIDLVQRYAPKLSLIVTSHQHFDHWQALEAVVAATG
:.:::***: * : * :: :: :* * ** . : .
Mflv_2765|M.gilvum_PYR-GCK APVLLHPADEVLWRMTHPDSDFRSVADNETLRVAGTELHALHTPGHSPGS
Mvan_3768|M.vanbaalenii_PYR-1 APVLLHPADEVLWRMTHPDSDFRSVSDGETLRVAGTELRALHTPGHSPGS
TH_1503|M.thermoresistible__bu APVLMHPADDMLWRMTHPDKDFRTVEHGQTLRAGGIELRALHTPGHSPGS
Rv2260|M.tuberculosis_H37Rv APVLMHPGDAVLWRMTHPDKSFRAVSDGDAVRVGGTELRALHTPGHSPGS
Mb2284|M.bovis_AF2122/97 APVLMHPGDAVLWRMTHPDKSFRAVSDGDAVRVGGTELRALHTPGHSPGS
MMAR_3351|M.marinum_M APVLLHPGDEMLWRMTHPDKDFRAVSDVETLRVGGTELRALHTPGHSPGS
MUL_1291|M.ulcerans_Agy99 APVLLHPGDEMLWRMTHPDKDFRAVSDVETLRVGGTELRALHTPGHSPGS
MAV_2180|M.avium_104 APVLLHPGDDVLWRMTHPDKDFRTIADGDTIDVAGTELLALHTPGHSPGS
MAB_4755c|M.abscessus_ATCC_199 APVLLHPADDVLWRMTHPDKDFRAVEDDMVLPVGGLELHALHTPGHSPGS
MSMEG_4342|M.smegmatis_MC2_155 APVLLHPADDMLWRDIHPDKEFRAVEDGLVLKAGEIEVHALHTPGHSPGS
MLBr_01391|M.leprae_Br4923 APTAVHELD----AEPLPVRPDRLLTNGDCVQIGELTFDVIHLRGHTPGS
**. :* * * * : . : . . .:* **:***
Mflv_2765|M.gilvum_PYR-GCK VCWHAPELN---------AVFSGDTLFQGGPGATGRSFSDFPTILESISG
Mvan_3768|M.vanbaalenii_PYR-1 VCWHAPELN---------AVFSGDTLFQGGPGATGRSFSDFPTILESISG
TH_1503|M.thermoresistible__bu VCWHAPELN---------AVFSGDTLFQGGPGATGRSFSDFPTILESIKG
Rv2260|M.tuberculosis_H37Rv VCWYAPELGPG-----TGTVFSGDTLFAGGPGATGRSYSDFPTILRSISG
Mb2284|M.bovis_AF2122/97 VCWYAPELGPG-----TGTVFSGDTLFAGGPGATGRSYSDFPTILRSISG
MMAR_3351|M.marinum_M VCWYAPELD---------VVFSGDTLFCGGPGATGRSFSDFPTILQSISE
MUL_1291|M.ulcerans_Agy99 VCWYAPELD---------VVFSGDTLFCGGPGATGRSFSDFPTILQSISE
MAV_2180|M.avium_104 VCWYAPELG---------VVFSGDTLFSGGPGATGRSYSDFPTILQSISG
MAB_4755c|M.abscessus_ATCC_199 VCWYAPELR---------AVFSGDTLFQGGPGATGRSFSDFPTILRSISG
MSMEG_4342|M.smegmatis_MC2_155 VCWSIPELN---------AVISGDTLFQGGPGATGRSYSDFPTILDSIKN
MLBr_01391|M.leprae_Br4923 IALALDGATSGPKTGRVTQLFTGDCLFPGGVGKT-WQRSDFTQLLDDVTT
:. :::** ** ** * * . ***. :* .:.
Mflv_2765|M.gilvum_PYR-GCK R-LGTLPGETVVYTGHGDSTTVGDEIVHYDEWVARGN
Mvan_3768|M.vanbaalenii_PYR-1 R-LGKLPGATVVYTGHGDSTTVGDEIVHYDEWVARGH
TH_1503|M.thermoresistible__bu R-LGKLPNETVVYTGHGDSTTIGDEIVNYDEWVKRGY
Rv2260|M.tuberculosis_H37Rv R-LGALPGDTVVHTGHGDSTTIGDEIVHYEEWVARGH
Mb2284|M.bovis_AF2122/97 R-LGALPGDTVVHTGHGDSTTIGDEIVHYEEWVARGH
MMAR_3351|M.marinum_M R-LGKLPGDTVVHTGHGDSTTIGDEIVHYEEWVARGH
MUL_1291|M.ulcerans_Agy99 R-LGTLPGDTVVHTGHGDSTTIGDEIVHYEEWVARGH
MAV_2180|M.avium_104 R-LGTLPGETVVHTGHGDSTTIGDEIVHYEEWVARGH
MAB_4755c|M.abscessus_ATCC_199 R-LGPLPEDTVVYTGHGDTTTIGDEIVHYDDWVARGH
MSMEG_4342|M.smegmatis_MC2_155 R-LGLLPAETVVYTGHGDTTTIGGELVNYDDWVKRGH
MLBr_01391|M.leprae_Br4923 RVFDVYADTTAIYPGHGDDTVLGAERPSLAEWRERGW
* :. . *.::.**** *.:* * :* **