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MAGIDKIVTHGTFELDGGSWEVDNNIWIVGDDSDVVVFDAAHTAEPIVAAVGNRNVVAVVCTHGHNDHVT VAPELGAALDAPVLLHPGDDVLWRMTHPDKDFRTIADGDTIDVAGTELLALHTPGHSPGSVCWYAPELGV VFSGDTLFSGGPGATGRSYSDFPTILQSISGRLGTLPGETVVHTGHGDSTTIGDEIVHYEEWVARGH*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_2180 | - | - | 100% (208) | metallo-beta-lactamase family protein |
| M. avium 104 | MAV_3136 | - | 4e-19 | 32.14% (196) | hydrolase |
| M. avium 104 | MAV_3461 | - | 1e-17 | 30.81% (185) | metallo-beta-lactamase family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2284 | - | 1e-107 | 83.41% (211) | hypothetical protein Mb2284 |
| M. gilvum PYR-GCK | Mflv_2765 | - | 1e-104 | 82.84% (204) | beta-lactamase domain-containing protein |
| M. tuberculosis H37Rv | Rv2260 | - | 1e-107 | 83.41% (211) | hypothetical protein Rv2260 |
| M. leprae Br4923 | MLBr_00493 | - | 1e-18 | 31.28% (195) | putative hydrolase |
| M. abscessus ATCC 19977 | MAB_4755c | - | 1e-101 | 79.71% (207) | hypothetical protein MAB_4755c |
| M. marinum M | MMAR_3351 | - | 1e-108 | 87.25% (204) | hypothetical protein MMAR_3351 |
| M. smegmatis MC2 155 | MSMEG_4342 | - | 2e-91 | 72.33% (206) | metallo-beta-lactamase family protein |
| M. thermoresistible (build 8) | TH_1503 | - | 1e-98 | 78.43% (204) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_1291 | - | 1e-108 | 88.06% (201) | hypothetical protein MUL_1291 |
| M. vanbaalenii PYR-1 | Mvan_3768 | - | 1e-104 | 82.84% (204) | beta-lactamase domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2765|M.gilvum_PYR-GCK -MNGGPIQRLVTSGTFELDGGSWDVDNNIWIVGDDKEVIVFDAAHTADPI
Mvan_3768|M.vanbaalenii_PYR-1 -MNGGPIQRLVTSGTFELDGGSWDVDNNIWIVGDDNEVVVFDAAHTADPI
TH_1503|M.thermoresistible__bu -VNGGPIQRVVTSGKFELDGGSWDVDNNIWIVGDDKEVIVFDAAHEAAPI
MMAR_3351|M.marinum_M ---MVHIDRVVTHGTFELDGGSWEVDNNIWLVGDDSDVVVFDAAHQAAPI
MUL_1291|M.ulcerans_Agy99 ---------MVTHGTFELDGGSWEVDNNIWLVGDDSDVVVFDAAHQAAPI
Mb2284|M.bovis_AF2122/97 ---MAAIERVITHGTFELDGGSWEVDNNIWLVGDDSEVVVFDAAHHAAPI
Rv2260|M.tuberculosis_H37Rv ---MAAIERVITHGTFELDGGSWEVDNNIWLVGDDSEVVVFDAAHHAAPI
MAV_2180|M.avium_104 --MMAGIDKIVTHGTFELDGGSWEVDNNIWIVGDDSDVVVFDAAHTAEPI
MAB_4755c|M.abscessus_ATCC_199 ---MSGIERVITRGTFELDGGSWEVDNNIWIVGEGDDVVVFDAAHSAQPI
MSMEG_4342|M.smegmatis_MC2_155 MTGPAQIQRVVTSGTFSLDGGTWDVDNNIWLVGDDNDVIVFDAAHTAAPI
MLBr_00493|M.leprae_Br4923 --------MLITG----FPAGMLQCNCYVLADRAGTDAVIVDPGQRAMGP
::* : .* : : : . :.::.*..: *
Mflv_2765|M.gilvum_PYR-GCK IEAVGGRH---VVAVVCTHGHNDHVTVAPQLGEALDAPVLLHPADEVLWR
Mvan_3768|M.vanbaalenii_PYR-1 IEAVGGRH---VVAVVCTHGHNDHVTVAPQLGQALDAPVLLHPADEVLWR
TH_1503|M.thermoresistible__bu KAAVGDRH---VVAVVCTHGHNDHITVAPELGSELDAPVLMHPADDMLWR
MMAR_3351|M.marinum_M IEAVAGRN---VVAVVCTHGHNDHVTVAPELGAALDAPVLLHPGDEMLWR
MUL_1291|M.ulcerans_Agy99 IEAVAGRN---VVAVVCTHGHNDHVTVAPELGAALDAPVLLHPGDEMLWR
Mb2284|M.bovis_AF2122/97 IDAVGGRK---VVAVICTHGHNDHVTVAPELGTALDAPVLMHPGDAVLWR
Rv2260|M.tuberculosis_H37Rv IDAVGGRK---VVAVICTHGHNDHVTVAPELGTALDAPVLMHPGDAVLWR
MAV_2180|M.avium_104 VAAVGNRN---VVAVVCTHGHNDHVTVAPELGAALDAPVLLHPGDDVLWR
MAB_4755c|M.abscessus_ATCC_199 IDAVGGRN---VVAVVCTHGHNDHITVAPELSQALDAPVLLHPADDVLWR
MSMEG_4342|M.smegmatis_MC2_155 VDAVAGRN---VVAVICTHGHNDHITVAPDLAVALDAPVLLHPADDMLWR
MLBr_00493|M.leprae_Br4923 LRRILDENRLTPSAVLLTHGHIDHMWSAQKVSDTYGCPTYIHPEDRFMLT
: ..: **: **** **: * .:. ..*. :** * .:
Mflv_2765|M.gilvum_PYR-GCK ------------------MTHPDSDFRSVADNETLRVAGTELHALHTPGH
Mvan_3768|M.vanbaalenii_PYR-1 ------------------MTHPDSDFRSVSDGETLRVAGTELRALHTPGH
TH_1503|M.thermoresistible__bu ------------------MTHPDKDFRTVEHGQTLRAGGIELRALHTPGH
MMAR_3351|M.marinum_M ------------------MTHPDKDFRAVSDVETLRVGGTELRALHTPGH
MUL_1291|M.ulcerans_Agy99 ------------------MTHPDKDFRAVSDVETLRVGGTELRALHTPGH
Mb2284|M.bovis_AF2122/97 ------------------MTHPDKSFRAVSDGDAVRVGGTELRALHTPGH
Rv2260|M.tuberculosis_H37Rv ------------------MTHPDKSFRAVSDGDAVRVGGTELRALHTPGH
MAV_2180|M.avium_104 ------------------MTHPDKDFRTIADGDTIDVAGTELLALHTPGH
MAB_4755c|M.abscessus_ATCC_199 ------------------MTHPDKDFRAVEDDMVLPVGGLELHALHTPGH
MSMEG_4342|M.smegmatis_MC2_155 ------------------DIHPDKEFRAVEDGLVLKAGEIEVHALHTPGH
MLBr_00493|M.leprae_Br4923 DPLFGFGPRVAQVVTGAFFREPKQVVELDRDGDKLDLGSVTVNVDHTPGH
.*.. .. . : . : . *****
Mflv_2765|M.gilvum_PYR-GCK SPGSVCWHAPELN----AVFSGDTLFQGGPGATGRSFSDFPTILESISGR
Mvan_3768|M.vanbaalenii_PYR-1 SPGSVCWHAPELN----AVFSGDTLFQGGPGATGRSFSDFPTILESISGR
TH_1503|M.thermoresistible__bu SPGSVCWHAPELN----AVFSGDTLFQGGPGATGRSFSDFPTILESIKGR
MMAR_3351|M.marinum_M SPGSVCWYAPELD----VVFSGDTLFCGGPGATGRSFSDFPTILQSISER
MUL_1291|M.ulcerans_Agy99 SPGSVCWYAPELD----VVFSGDTLFCGGPGATGRSFSDFPTILQSISER
Mb2284|M.bovis_AF2122/97 SPGSVCWYAPELGPGTGTVFSGDTLFAGGPGATGRSYSDFPTILRSISGR
Rv2260|M.tuberculosis_H37Rv SPGSVCWYAPELGPGTGTVFSGDTLFAGGPGATGRSYSDFPTILRSISGR
MAV_2180|M.avium_104 SPGSVCWYAPELG----VVFSGDTLFSGGPGATGRSYSDFPTILQSISGR
MAB_4755c|M.abscessus_ATCC_199 SPGSVCWYAPELR----AVFSGDTLFQGGPGATGRSFSDFPTILRSISGR
MSMEG_4342|M.smegmatis_MC2_155 SPGSVCWSIPELN----AVISGDTLFQGGPGATGRSYSDFPTILDSIKNR
MLBr_00493|M.leprae_Br4923 TRGSVCFWVAADT---DVVLTGDTLFERTIGRTDLFGGSGRDLYRSIVEK
: ****: . .*::***** * *. .. : ** :
Mflv_2765|M.gilvum_PYR-GCK LGTLPGETVVYTGHGDSTTVGDEIVHYDEWVARGN
Mvan_3768|M.vanbaalenii_PYR-1 LGKLPGATVVYTGHGDSTTVGDEIVHYDEWVARGH
TH_1503|M.thermoresistible__bu LGKLPNETVVYTGHGDSTTIGDEIVNYDEWVKRGY
MMAR_3351|M.marinum_M LGKLPGDTVVHTGHGDSTTIGDEIVHYEEWVARGH
MUL_1291|M.ulcerans_Agy99 LGTLPGDTVVHTGHGDSTTIGDEIVHYEEWVARGH
Mb2284|M.bovis_AF2122/97 LGALPGDTVVHTGHGDSTTIGDEIVHYEEWVARGH
Rv2260|M.tuberculosis_H37Rv LGALPGDTVVHTGHGDSTTIGDEIVHYEEWVARGH
MAV_2180|M.avium_104 LGTLPGETVVHTGHGDSTTIGDEIVHYEEWVARGH
MAB_4755c|M.abscessus_ATCC_199 LGPLPEDTVVYTGHGDTTTIGDEIVHYDDWVARGH
MSMEG_4342|M.smegmatis_MC2_155 LGLLPAETVVYTGHGDTTTIGGELVNYDDWVKRGH
MLBr_00493|M.leprae_Br4923 LLVLDDKTVVLPGHGNSTTIGAERR-FNPFLEGL-
* * *** .***::**:* * :: ::