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VTHGTFELDGGSWEVDNNIWLVGDDSDVVVFDAAHQAAPIIEAVAGRNVVAVVCTHGHNDHVTVAPELGA ALDAPVLLHPGDEMLWRMTHPDKDFRAVSDVETLRVGGTELRALHTPGHSPGSVCWYAPELDVVFSGDTL FCGGPGATGRSFSDFPTILQSISERLGTLPGDTVVHTGHGDSTTIGDEIVHYEEWVARGH*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. ulcerans Agy99 | MUL_1291 | - | - | 100% (201) | hypothetical protein MUL_1291 |
M. ulcerans Agy99 | MUL_1621 | - | 1e-19 | 32.66% (199) | hypothetical protein MUL_1621 |
M. ulcerans Agy99 | MUL_1731 | - | 1e-17 | 29.63% (189) | Zn-dependent glyoxylase |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb2284 | - | 1e-106 | 86.83% (205) | hypothetical protein Mb2284 |
M. gilvum PYR-GCK | Mflv_2765 | - | 1e-103 | 84.08% (201) | beta-lactamase domain-containing protein |
M. tuberculosis H37Rv | Rv2260 | - | 1e-106 | 86.83% (205) | hypothetical protein Rv2260 |
M. leprae Br4923 | MLBr_00493 | - | 3e-19 | 31.79% (195) | putative hydrolase |
M. abscessus ATCC 19977 | MAB_4755c | - | 1e-100 | 83.08% (201) | hypothetical protein MAB_4755c |
M. marinum M | MMAR_3351 | - | 1e-119 | 99.50% (201) | hypothetical protein MMAR_3351 |
M. avium 104 | MAV_2180 | - | 1e-107 | 88.06% (201) | metallo-beta-lactamase family protein |
M. smegmatis MC2 155 | MSMEG_4342 | - | 2e-92 | 75.12% (201) | metallo-beta-lactamase family protein |
M. thermoresistible (build 8) | TH_1503 | - | 2e-97 | 79.60% (201) | CONSERVED HYPOTHETICAL PROTEIN |
M. vanbaalenii PYR-1 | Mvan_3768 | - | 1e-103 | 85.57% (201) | beta-lactamase domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment Mflv_2765|M.gilvum_PYR-GCK -MNGGPIQRLVTSGTFELDGGSWDVDNNIWIVGDDKEVIVFDAAHTADPI Mvan_3768|M.vanbaalenii_PYR-1 -MNGGPIQRLVTSGTFELDGGSWDVDNNIWIVGDDNEVVVFDAAHTADPI TH_1503|M.thermoresistible__bu -VNGGPIQRVVTSGKFELDGGSWDVDNNIWIVGDDKEVIVFDAAHEAAPI MUL_1291|M.ulcerans_Agy99 ---------MVTHGTFELDGGSWEVDNNIWLVGDDSDVVVFDAAHQAAPI MMAR_3351|M.marinum_M ---MVHIDRVVTHGTFELDGGSWEVDNNIWLVGDDSDVVVFDAAHQAAPI Mb2284|M.bovis_AF2122/97 ---MAAIERVITHGTFELDGGSWEVDNNIWLVGDDSEVVVFDAAHHAAPI Rv2260|M.tuberculosis_H37Rv ---MAAIERVITHGTFELDGGSWEVDNNIWLVGDDSEVVVFDAAHHAAPI MAV_2180|M.avium_104 --MMAGIDKIVTHGTFELDGGSWEVDNNIWIVGDDSDVVVFDAAHTAEPI MAB_4755c|M.abscessus_ATCC_199 ---MSGIERVITRGTFELDGGSWEVDNNIWIVGEGDDVVVFDAAHSAQPI MSMEG_4342|M.smegmatis_MC2_155 MTGPAQIQRVVTSGTFSLDGGTWDVDNNIWLVGDDNDVIVFDAAHTAAPI MLBr_00493|M.leprae_Br4923 --------MLITG----FPAGMLQCNCYVLADRAGTDAVIVDPGQRAMGP ::* : .* : : : . :.::.*..: * Mflv_2765|M.gilvum_PYR-GCK IEAVGGRH---VVAVVCTHGHNDHVTVAPQLGEALDAPVLLHPADEVLWR Mvan_3768|M.vanbaalenii_PYR-1 IEAVGGRH---VVAVVCTHGHNDHVTVAPQLGQALDAPVLLHPADEVLWR TH_1503|M.thermoresistible__bu KAAVGDRH---VVAVVCTHGHNDHITVAPELGSELDAPVLMHPADDMLWR MUL_1291|M.ulcerans_Agy99 IEAVAGRN---VVAVVCTHGHNDHVTVAPELGAALDAPVLLHPGDEMLWR MMAR_3351|M.marinum_M IEAVAGRN---VVAVVCTHGHNDHVTVAPELGAALDAPVLLHPGDEMLWR Mb2284|M.bovis_AF2122/97 IDAVGGRK---VVAVICTHGHNDHVTVAPELGTALDAPVLMHPGDAVLWR Rv2260|M.tuberculosis_H37Rv IDAVGGRK---VVAVICTHGHNDHVTVAPELGTALDAPVLMHPGDAVLWR MAV_2180|M.avium_104 VAAVGNRN---VVAVVCTHGHNDHVTVAPELGAALDAPVLLHPGDDVLWR MAB_4755c|M.abscessus_ATCC_199 IDAVGGRN---VVAVVCTHGHNDHITVAPELSQALDAPVLLHPADDVLWR MSMEG_4342|M.smegmatis_MC2_155 VDAVAGRN---VVAVICTHGHNDHITVAPDLAVALDAPVLLHPADDMLWR MLBr_00493|M.leprae_Br4923 LRRILDENRLTPSAVLLTHGHIDHMWSAQKVSDTYGCPTYIHPEDRFMLT : ..: **: **** **: * .:. ..*. :** * .: Mflv_2765|M.gilvum_PYR-GCK ------------------MTHPDSDFRSVADNETLRVAGTELHALHTPGH Mvan_3768|M.vanbaalenii_PYR-1 ------------------MTHPDSDFRSVSDGETLRVAGTELRALHTPGH TH_1503|M.thermoresistible__bu ------------------MTHPDKDFRTVEHGQTLRAGGIELRALHTPGH MUL_1291|M.ulcerans_Agy99 ------------------MTHPDKDFRAVSDVETLRVGGTELRALHTPGH MMAR_3351|M.marinum_M ------------------MTHPDKDFRAVSDVETLRVGGTELRALHTPGH Mb2284|M.bovis_AF2122/97 ------------------MTHPDKSFRAVSDGDAVRVGGTELRALHTPGH Rv2260|M.tuberculosis_H37Rv ------------------MTHPDKSFRAVSDGDAVRVGGTELRALHTPGH MAV_2180|M.avium_104 ------------------MTHPDKDFRTIADGDTIDVAGTELLALHTPGH MAB_4755c|M.abscessus_ATCC_199 ------------------MTHPDKDFRAVEDDMVLPVGGLELHALHTPGH MSMEG_4342|M.smegmatis_MC2_155 ------------------DIHPDKEFRAVEDGLVLKAGEIEVHALHTPGH MLBr_00493|M.leprae_Br4923 DPLFGFGPRVAQVVTGAFFREPKQVVELDRDGDKLDLGSVTVNVDHTPGH .*.. .. . : . : . ***** Mflv_2765|M.gilvum_PYR-GCK SPGSVCWHAPELN----AVFSGDTLFQGGPGATGRSFSDFPTILESISGR Mvan_3768|M.vanbaalenii_PYR-1 SPGSVCWHAPELN----AVFSGDTLFQGGPGATGRSFSDFPTILESISGR TH_1503|M.thermoresistible__bu SPGSVCWHAPELN----AVFSGDTLFQGGPGATGRSFSDFPTILESIKGR MUL_1291|M.ulcerans_Agy99 SPGSVCWYAPELD----VVFSGDTLFCGGPGATGRSFSDFPTILQSISER MMAR_3351|M.marinum_M SPGSVCWYAPELD----VVFSGDTLFCGGPGATGRSFSDFPTILQSISER Mb2284|M.bovis_AF2122/97 SPGSVCWYAPELGPGTGTVFSGDTLFAGGPGATGRSYSDFPTILRSISGR Rv2260|M.tuberculosis_H37Rv SPGSVCWYAPELGPGTGTVFSGDTLFAGGPGATGRSYSDFPTILRSISGR MAV_2180|M.avium_104 SPGSVCWYAPELG----VVFSGDTLFSGGPGATGRSYSDFPTILQSISGR MAB_4755c|M.abscessus_ATCC_199 SPGSVCWYAPELR----AVFSGDTLFQGGPGATGRSFSDFPTILRSISGR MSMEG_4342|M.smegmatis_MC2_155 SPGSVCWSIPELN----AVISGDTLFQGGPGATGRSYSDFPTILDSIKNR MLBr_00493|M.leprae_Br4923 TRGSVCFWVAADT---DVVLTGDTLFERTIGRTDLFGGSGRDLYRSIVEK : ****: . .*::***** * *. .. : ** : Mflv_2765|M.gilvum_PYR-GCK LGTLPGETVVYTGHGDSTTVGDEIVHYDEWVARGN Mvan_3768|M.vanbaalenii_PYR-1 LGKLPGATVVYTGHGDSTTVGDEIVHYDEWVARGH TH_1503|M.thermoresistible__bu LGKLPNETVVYTGHGDSTTIGDEIVNYDEWVKRGY MUL_1291|M.ulcerans_Agy99 LGTLPGDTVVHTGHGDSTTIGDEIVHYEEWVARGH MMAR_3351|M.marinum_M LGKLPGDTVVHTGHGDSTTIGDEIVHYEEWVARGH Mb2284|M.bovis_AF2122/97 LGALPGDTVVHTGHGDSTTIGDEIVHYEEWVARGH Rv2260|M.tuberculosis_H37Rv LGALPGDTVVHTGHGDSTTIGDEIVHYEEWVARGH MAV_2180|M.avium_104 LGTLPGETVVHTGHGDSTTIGDEIVHYEEWVARGH MAB_4755c|M.abscessus_ATCC_199 LGPLPEDTVVYTGHGDTTTIGDEIVHYDDWVARGH MSMEG_4342|M.smegmatis_MC2_155 LGLLPAETVVYTGHGDTTTIGGELVNYDDWVKRGH MLBr_00493|M.leprae_Br4923 LLVLDDKTVVLPGHGNSTTIGAERR-FNPFLEGL- * * *** .***::**:* * :: ::