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TALEVLGGWPVPAAAAAVIGPAGVLATHGDTARVFALASVTKPLVARAAQVAVEEGVVNLDTPAGPPGST VRHLLAHTSGLAMHSDQALARPGTRRMYSNYGFTVLAESVQRESGIEFGRYLTEAVCEPLGMVTTRLDGG PAAAGFGATSTVADLAVFAGDLLRPSTVSAQMHADATTVQFPGLDGVLPGYGVQRPNDWGLGFEIRNSKS PHWTGECNSTRTFGHFGQSGGFIWVDPKADLALVVLTARDFGDWALDLWPAISDAVLAEYT*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv2257c | - | - | 100% (272) | hypothetical protein Rv2257c |
| M. tuberculosis H37Rv | Rv1922 | - | 4e-07 | 30.66% (137) | lipoprotein |
| M. tuberculosis H37Rv | Rv0907 | - | 9e-06 | 28.19% (149) | hypothetical protein Rv0907 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2281c | - | 1e-158 | 100.00% (272) | hypothetical protein Mb2281c |
| M. gilvum PYR-GCK | Mflv_2769 | - | 1e-105 | 69.00% (271) | beta-lactamase |
| M. leprae Br4923 | MLBr_01782 | - | 1e-122 | 76.38% (271) | hypothetical protein MLBr_01782 |
| M. abscessus ATCC 19977 | MAB_1870 | - | 1e-101 | 66.42% (271) | putative beta-lactamase |
| M. marinum M | MMAR_3348 | - | 1e-127 | 78.97% (271) | hypothetical protein MMAR_3348 |
| M. avium 104 | MAV_2183 | - | 1e-124 | 76.84% (272) | beta-lactamase |
| M. smegmatis MC2 155 | MSMEG_4337 | - | 1e-112 | 73.96% (265) | beta-lactamase |
| M. thermoresistible (build 8) | TH_1504 | - | 1e-114 | 72.69% (271) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_1294 | - | 1e-126 | 78.60% (271) | hypothetical protein MUL_1294 |
| M. vanbaalenii PYR-1 | Mvan_3764 | - | 1e-111 | 71.96% (271) | beta-lactamase |
CLUSTAL 2.0.9 multiple sequence alignment
Rv2257c|M.tuberculosis_H37Rv MTALEVLGGWPVPAAAAAVIGPAGVLATHGDTARVFALASVTKPLVARAA
Mb2281c|M.bovis_AF2122/97 MTALEVLGGWPVPAAAAAVIGPAGVLATHGDTARVFALASVTKPLVARAA
MLBr_01782|M.leprae_Br4923 MVALDALDDWPVPTTAAAVVGPTGVLAARGDTEQVFPLASVTKPLVARAV
MAV_2183|M.avium_104 MAALDALDEWPVGAVAAAVIGPTGVLAGHGDAERVFALASVTKPLAARAV
MMAR_3348|M.marinum_M MAALDALDDWPVPAAAAAVIGPTGVLATHGNVEKVFALASVTKPMAARAA
MUL_1294|M.ulcerans_Agy99 MAALDALDDWPVPAAAAAVIGPTGVLATHGNVEKVFALASVTKPMAARAA
MSMEG_4337|M.smegmatis_MC2_155 -----MIDEWPVPTAAAAVIGPSGVLATHGDDAKPFALASVTKLLVARAA
TH_1504|M.thermoresistible__bu MGALDVLADWPVDNVAATVVGPDGVRADRGDLRREFALASVTKPLAARAA
Mflv_2769|M.gilvum_PYR-GCK MSALDVLSDWPVPNVAAAVVGGKGVLADHGDTRHRFPLASVTKLLVARAA
Mvan_3764|M.vanbaalenii_PYR-1 MSALDALNDWPVPTAAAAVVGPSGVLARHGDTGRRFPLASVTKPLVARAA
MAB_1870|M.abscessus_ATCC_1997 MGALDLVADWPVSTVAAAVVAPEGIRAQIGPVTQQFALASVTKPLVARAA
: *** .**:*:. *: * * : *.****** :.***.
Rv2257c|M.tuberculosis_H37Rv QVAVEEGVVNLDTPAGPPGSTVRHLLAHTSGLAMHSDQALARPGTRRMYS
Mb2281c|M.bovis_AF2122/97 QVAVEEGVVNLDTPAGPPGSTVRHLLAHTSGLAMHSDQALARPGTRRMYS
MLBr_01782|M.leprae_Br4923 QIAIEEGVVDLDTVAGPPGSTIRHLLAHASGLAMHSKYVMAPPGTRRIYS
MAV_2183|M.avium_104 HVAVEEGAVELDAAAGPPGATIRHLLAHTSGLSMHSDQVLAPPGTRRIYS
MMAR_3348|M.marinum_M QIAIEEGVVDLDTPAGPPDSTIRHLLAHTSGLSMHTNQVLARPGTRRMYS
MUL_1294|M.ulcerans_Agy99 QIAIEEGVVDLDTPAGPPDSTIRHLLAHTSGLPMHTNQVLARPGTRRMYS
MSMEG_4337|M.smegmatis_MC2_155 QVAIEEGVVELDTPAGPDGSTVRHLLAHTSGVAMNSADTVAQVGQRRVYS
TH_1504|M.thermoresistible__bu QIAVEEGVVELDTPAGPPGSTVRHLLAHTSGVSMNSAETLNEPGQRRVYS
Mflv_2769|M.gilvum_PYR-GCK QIAVEEGAVELDSAAGPTGSTVRHLLAHTAGYEMTSSKVIARPGTRRVYS
Mvan_3764|M.vanbaalenii_PYR-1 QVAVEEGAVDLDSEAGPPGATVRHLLAHAAGYEMSSSKVLAAPGTRRIYS
MAB_1870|M.abscessus_ATCC_1997 QVALEEGAVDLTTPAGPSGSTVEHLLAHASGLSLLSGAVMAKPGTRRIYS
::*:***.*:* : *** .:*:.*****::* : : .: * **:**
Rv2257c|M.tuberculosis_H37Rv NYGFTVLAESVQRESGIEFGRYLTEAVCEPLGMVTTRLDGGPAAAGFGAT
Mb2281c|M.bovis_AF2122/97 NYGFTVLAESVQRESGIEFGRYLTEAVCEPLGMVTTRLDGGPAAAGFGAT
MLBr_01782|M.leprae_Br4923 NYGFRVLAETVQREAGIGFSRYLTEAVLEPLAMTATKLEDGTWAAGFGAT
MAV_2183|M.avium_104 NQGFTVLGETLEEETGIEFARYLHEAVCQPLGMTATRLDGGAVAAGFGAT
MMAR_3348|M.marinum_M NYGFTALAEAVAQESGIEFSSYLAEAVFEPLGMSTSKLEGGAAAAGFGAT
MUL_1294|M.ulcerans_Agy99 NYGFTALAEAVAQESGIEFSSYLAEAVFEPLGMSTSKLEGGAAAAGFGAT
MSMEG_4337|M.smegmatis_MC2_155 NFGFGLLAHAIEDAAEIEFGRYLTEAVFEPLGMSTSKLLGGADAAGFGVT
TH_1504|M.thermoresistible__bu NYGFRLLAEKIEQESGIGFAEYFHEAVCEPLGMSDTALPGGAAAAGFGAG
Mflv_2769|M.gilvum_PYR-GCK NYGFTVLAETIESESLIPFPDYLAESVFAPLNLGDTDLDGGAEAAGYGVT
Mvan_3764|M.vanbaalenii_PYR-1 NYGFTVLAEKIEAESSIPFATYLAESVFEPLAMSGTALDGGAEAAGYGVT
MAB_1870|M.abscessus_ATCC_1997 NYGFAVLAHAVEAGATIEFDAYLREAVLEPLGMSSTTLPGGADTAGYGAS
* ** *.. : : * * *: *:* ** : : * .*. :**:*.
Rv2257c|M.tuberculosis_H37Rv STVADLAVFAGDLLRPSTVSAQMHADATTVQFPGLDGVLPGYGVQRPNDW
Mb2281c|M.bovis_AF2122/97 STVADLAVFAGDLLRPSTVSAQMHADATTVQFPGLDGVLPGYGVQRPNDW
MLBr_01782|M.leprae_Br4923 STVADLAAFANDLLRPATVSAQIHAEATSVQFPDLDGVLPGHGVQRPNDW
MAV_2183|M.avium_104 STVADLAAFAGDLLRPTTVSARLHAEATTVQFPGLDGVLPGYGVQRPNDW
MMAR_3348|M.marinum_M STVGDLALFAGDLLRPSTVSPPMHAEAIAVQFPGLDGVLPGFGVQRPNDW
MUL_1294|M.ulcerans_Agy99 STVGDLALFTGDLLRPSTVSPPMHAEAIAVQFPGLDGVLPGFGVQRPNDW
MSMEG_4337|M.smegmatis_MC2_155 STVSDLARFAGDLLRPALVSQQMHDEATSVQFPGVNGVLPGFGSQRPNDW
TH_1504|M.thermoresistible__bu STVADLALFAVDLLRPRLVSQQMHDEATSVQFPGLDGVLPGFGVQRPNDW
Mflv_2769|M.gilvum_PYR-GCK STVEDLVAFAGDLLTPALVSQQMHDDAISVQFPGLDGVLPGFGVQRPNDW
Mvan_3764|M.vanbaalenii_PYR-1 STVEDLVAFARDLLEPVTVSEQMHREAISVQFPGLDGVLPGFGVQRPNDW
MAB_1870|M.abscessus_ATCC_1997 STVADLAAFVGDLLRPHLVSAETHQRATHVVFPGLDGVLPGYGVQRPNDW
*** **. *. *** * ** * * * **.::*****.* ******
Rv2257c|M.tuberculosis_H37Rv GLGFEIRNSKSPHWTGECNSTRTFGHFGQSGGFIWVDPKADLALVVLTAR
Mb2281c|M.bovis_AF2122/97 GLGFEIRNSKSPHWTGECNSTRTFGHFGQSGGFIWVDPKADLALVVLTAR
MLBr_01782|M.leprae_Br4923 GLGYEIKNSKLPHWTGTLNSARTYGHFGQSGGFIWADPEAELALVVLTDR
MAV_2183|M.avium_104 GLGFELRDGKAPHWTGAANSARTYGHFGQAGGFIWADPDIERALVVLTDR
MMAR_3348|M.marinum_M GLGFEIKSAKSPHWTGIRNSPRTYGHFGQAGGFIWVDPEADLALVVLTDR
MUL_1294|M.ulcerans_Agy99 GLGFEIKSAKSPHWTGIRNSPRTYGHFGQAGGFIWVDPEADLALVVLTDR
MSMEG_4337|M.smegmatis_MC2_155 GLGFEIRDGKTPHWTGSSNSPRTFGHFGQSGTFLWVDPVADLALLVLTDR
TH_1504|M.thermoresistible__bu GLGFEIRGTKSPHWTGSANSPRTFGHFGQSGTFLWVDPAVDLALVVLTDR
Mflv_2769|M.gilvum_PYR-GCK GLGFEIRDGKSPHWTGGGNSPGTFGHFGQSGTFLWVDPGASVALIVLTDR
Mvan_3764|M.vanbaalenii_PYR-1 GLGFEIRGGKSPHWTGSANSTRTFGHFGQSGTFLWVDPDAALALVVLTDR
MAB_1870|M.abscessus_ATCC_1997 GLGFEIKGSKLPHWTGAENSPATYGHFGQAGTFIWVDPAVDLGLVVLTDR
***:*::. * ***** **. *:*****:* *:*.** .*:*** *
Rv2257c|M.tuberculosis_H37Rv DFGDWALDLWPAISDAVLAEYT--
Mb2281c|M.bovis_AF2122/97 DFGDWALDLWPAISDAVLAEYT--
MLBr_01782|M.leprae_Br4923 DFGEWALQLWPAISDAVISEYAR-
MAV_2183|M.avium_104 DFGEWALDRWPAISDAVISEYS--
MMAR_3348|M.marinum_M DFGDWAREPWPALSDSVLAEYA--
MUL_1294|M.ulcerans_Agy99 DFGDWAREPWPALSDSVLAEYA--
MSMEG_4337|M.smegmatis_MC2_155 DFGDWTYPLWPAISDGVLREIGTH
TH_1504|M.thermoresistible__bu NFGNWAYERWPALSDGVLREFASH
Mflv_2769|M.gilvum_PYR-GCK TFGDWAHAVMPALSDEVLREFGAD
Mvan_3764|M.vanbaalenii_PYR-1 KFGDWAHTVMPALSDEVLREFGAD
MAB_1870|M.abscessus_ATCC_1997 PFDGWANQVWPQLSDAVLAEFG--
*. *: * :** *: *