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M. tuberculosis H37Rv Rv2203 (-)

annotation: POSSIBLE CONSERVED MEMBRANE PROTEIN
coordinates: 2468231 - 2468923
length: 230

MPGPHSPNPGVGTNGPAPYPEPSSHEPQALDYPHDLGAAEPAFAPGPADDAALPPAAYPGVPPQVSYPKR
RHKRLLIGIVVALALVSAMTAAIIYGVRTNGANTAGTFSEGPAKTAIQGYLNALENRDVDTIVRNALCGI
HDGVRDKRSDQALAKLSSDAFRKQFSQVEVTSIDKIVYWSQYQAQVLFTMQVTPAAGGPPRGQVQGIAQL
LFQRGQVLVCSYVLRTAGSY
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv2203--100% (230)POSSIBLE CONSERVED MEMBRANE PROTEIN
M. tuberculosis H37RvRv2839cinfB2e-0537.10% (62) translation initiation factor IF-2

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2226-1e-133100.00% (230) hypothetical protein Mb2226
M. gilvum PYR-GCKMflv_2946-4e-4546.28% (242) hypothetical protein Mflv_2946
M. leprae Br4923MLBr_00872-2e-6872.35% (170) hypothetical protein MLBr_00872
M. abscessus ATCC 19977MAB_1958c-2e-2736.79% (193) hypothetical protein MAB_1958c
M. marinum MMMAR_3247-2e-9775.32% (231) hypothetical protein MMAR_3247
M. avium 104MAV_2288-6e-8167.23% (235) hypothetical protein MAV_2288
M. smegmatis MC2 155MSMEG_4271-6e-4348.92% (186) hypothetical protein MSMEG_4271
M. thermoresistible (build 8)TH_3594-6e-3945.00% (180) PUTATIVE hypothetical protein Mflv_2946
M. ulcerans Agy99MUL_3560-5e-9076.17% (214) hypothetical protein MUL_3560
M. vanbaalenii PYR-1Mvan_3567-4e-4747.68% (237) hypothetical protein Mvan_3567

CLUSTAL 2.0.9 multiple sequence alignment


Rv2203|M.tuberculosis_H37Rv         MPGPHSPNPGVGTNGPAPYPEPSSHEPQALDYPHDLGAAEPAFAPGPADD
Mb2226|M.bovis_AF2122/97            MPGPHSPNPGVGTNGPAPYPEPSSHEPQALDYPHDLGAAEPAFAPGPADD
MMAR_3247|M.marinum_M               MAGPHPSNPAVSTEGPMPYPENGPNEP--LEYPHDLGGAEPAFGTPPADG
MUL_3560|M.ulcerans_Agy99           ----------------MPYPENGPNEP--LEYPHDLGGAEPAFGVPPADG
MLBr_00872|M.leprae_Br4923          --------------------------------------------------
MAV_2288|M.avium_104                MAGPHSPNHTVGGQGPTP-----PSESQPLEFPDHPNAGDTGYAAAPQAP
Mflv_2946|M.gilvum_PYR-GCK          MTGPYPPPYGAGPAGPQMYPEPYPQQS----Y-PPYAAPYPDGGPG----
Mvan_3567|M.vanbaalenii_PYR-1       MTGPYPPPYGAGPAGPQMYPEPYPPQT----Y-PPLGATYP---------
TH_3594|M.thermoresistible__bu      --------------------VPYP---------EPAGSAYP---------
MSMEG_4271|M.smegmatis_MC2_155      MTDVQITRGAFLMTGSYQYPESVPPQQ----YPEQIPSAYP---------
MAB_1958c|M.abscessus_ATCC_199      ------------MAEPGYSTVPYPGLP-----------------------
                                                                                      

Rv2203|M.tuberculosis_H37Rv         AALPPAAYPGVPPQVS-YPKRRHKR-LLIGIVVALALVSA-MTAAIIYGV
Mb2226|M.bovis_AF2122/97            AALPPAAYPGVPPQVS-YPKRRHKR-LLIGIVVALALVSA-MTAAIIYGV
MMAR_3247|M.marinum_M               PPRLPVSYPGLPPAPGGYRNRRPRR-LLIGTLLALALVGA-LTATIVYGV
MUL_3560|M.ulcerans_Agy99           PPRLPVSYPGLPPAPGGYRNRRPKR-LLIGTLLALALVGA-LTATIVYGV
MLBr_00872|M.leprae_Br4923          ---------MLPPAVS-YPRRRSKR-LIISVLVAIALVAA-MTAVIIYGV
MAV_2288|M.avium_104                PG--SANYAGPPPAPAPYPPRRSKRRLIVGLALAVALVAV-MTVAIVYGV
Mflv_2946|M.gilvum_PYR-GCK          ----PVYPGALPPPVQYPKRRRSPWIIVAVALAAVVAVGA-VITGVTLAA
Mvan_3567|M.vanbaalenii_PYR-1       --------GTLPPPVQYPKRRR-PWIIAVVAAVAVLAVVG-VVAAVALTG
TH_3594|M.thermoresistible__bu      --------GMLPPPVQYP-GRR--WRRVLTVLAVIGVVVG-AGAAVVFAT
MSMEG_4271|M.smegmatis_MC2_155      --------GMLPPPVPYPKRRR--WPKVLAAVLAVAVLAG-VVTAVVQVT
MAB_1958c|M.abscessus_ATCC_199      ---------PMPPPVDYPERKR----KVPGWLAPAAVVAALLILALVLGF
                                               **       :*               :       :    

Rv2203|M.tuberculosis_H37Rv         RTNGANTAGTFSEGPAKTAIQGYLNALENRDVDTIVRNALCGIHDGVRDK
Mb2226|M.bovis_AF2122/97            RTNGANTAGTFSEGPAKTAIQGYLNALENRDVDTIVRNALCGIHDGVRDK
MMAR_3247|M.marinum_M               RTNGTNSSGTLSEGAAKTAIQGYLNALEHRDVDVIVRNALCGIYDGVKDK
MUL_3560|M.ulcerans_Agy99           RTNGTNSSGTLSEGAAKTAIQGYLNALEHRDVDVIVRNALCGIYNGVKDK
MLBr_00872|M.leprae_Br4923          RTNGSKTGGTFSEVTAKTAIEDYLKALEQSNINTIARNALCGMYDSVRDQ
MAV_2288|M.avium_104                RTNGANTGATFSEGAAKTAIQGYLDALEHRDIDEIARNALCGLYDGVQDK
Mflv_2946|M.gilvum_PYR-GCK          GREDQGATGTLTETSARAAIQDYLDALTDGDDERVARHTLCGLFDAVKER
Mvan_3567|M.vanbaalenii_PYR-1       SRDEAAPSGALTEASAQTAIQDYLDALTNADVETVARHTLCGLYDAVNER
TH_3594|M.thermoresistible__bu      RGGSGRPGAGFTETAARAEIQRYLDALADGDDETVARHALCGMYDEVKQR
MSMEG_4271|M.smegmatis_MC2_155      R-SSGSESGVVTETQARDAIQEYLSALIDADDETVARHTMCGLFDAVRDR
MAB_1958c|M.abscessus_ATCC_199      LTKNSGVSQRPSEAKIEQTIQAYLDAMARLDTVTLARNAGCGLYDAVRDK
                                               :*   .  *: **.*:   :   :.*:: **:.: *.::

Rv2203|M.tuberculosis_H37Rv         RSDQALAKLSSDAFRKQFSQVEVTSIDKIVYWSQYQAQVLFTMQVTPAAG
Mb2226|M.bovis_AF2122/97            RSDQALAKLSSDAFRKQFSQVEVTSIDKIVYWSQYQAQVLFTMQVTPAAG
MMAR_3247|M.marinum_M               RSDQALAKLSSDAFRKQFSQADVTSIDKIVYWSQYQAQVLFTMQVTPATG
MUL_3560|M.ulcerans_Agy99           RSDQALAKLSSDAFRKQFSQADVTSIDEIVYWSQYQAQVLFTMQVTPATG
MLBr_00872|M.leprae_Br4923          RPDQALAQLSSDAFRKQFSQVELTSIDQIVYWSPYQAQVLFTMRTSPATG
MAV_2288|M.avium_104                RSDQALAKLSSDAFRKQFSEVQVTSIDKIVYLSQYQAQALFSMRVSPVSG
Mflv_2946|M.gilvum_PYR-GCK          RSDLALANLSSDAFRKQYDSAEVTSIDKMVRSSPTQAQVLFTMRVVPASG
Mvan_3567|M.vanbaalenii_PYR-1       RSDLALANLSSDAFRKQYESAEVTSIDKMVLSSPSQAQVLFTMRVTPAGG
TH_3594|M.thermoresistible__bu      RSDLEVATLNSDAFRKQYDRAEVTGIDKMVRLSVNQARVLFSMRVVPAGG
MSMEG_4271|M.smegmatis_MC2_155      KADLAVASLAGDTFRKQFGNVEVTSIDKIVPWSTTQAQVLFTMRVAPARS
MAB_1958c|M.abscessus_ATCC_199      DTDDTIVRANAQQFVATFGTATVKSIDKIVYFSQYQLKVLFTATSQ----
                                     .*  :.   .: *   :  . :..**::*  *  * :.**:        

Rv2203|M.tuberculosis_H37Rv         G-----PPRGQVQGIAQLLFQR----GQVLVCSYVLRTAGSY
Mb2226|M.bovis_AF2122/97            G-----PPRGQVQGIAQLLFQR----GQVLVCSYVLRTAGSY
MMAR_3247|M.marinum_M               G-----PPKGQVQGIAQLLFQR----GQIMVCSYVLRTAGQY
MUL_3560|M.ulcerans_Agy99           G-----PPNGQVQGIAQLLFQR----GQIMVCSYVLRTAGQY
MLBr_00872|M.leprae_Br4923          G-----PKRRQIQGIAQLLYRR----NQVLVCSYMLRTADSH
MAV_2288|M.avium_104                G-----PARGQVQGIAQLLFQR----GQIMVCSYVLRTGGSY
Mflv_2946|M.gilvum_PYR-GCK          SSRNA-PQEADEQAVAQVLSID----DEVLVCSYLPRTAGQY
Mvan_3567|M.vanbaalenii_PYR-1       SSRNQ-PQQADEQAVAQLLSID----DEVLVCSYLPRTAGQY
TH_3594|M.thermoresistible__bu      TSARE-PAETEVQGIAELLYQD----NEILVCNYLVRTGSQY
MSMEG_4271|M.smegmatis_MC2_155      SSRGQRPPAEEQQGVAQLLVDKTDGGDDVLVCSYVLRTGGQY
MAB_1958c|M.abscessus_ATCC_199      ------KRKDAPQGQAELLLNE----GKIYVCSAYMRGANAY
                                                *. *::*       ..: **.   * .. :