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EVFHWLQHDIVDRGRLPLLCCLVAFVLTFLVTRSFVRFIHRRAADGRPARWWQPRNVHIGSVHIHHVAFG VVLVMISGLTLVTLSVDGREPEFTIAASIFGVGAALVLDEYALILHLSDVYWEEDGRTSVDAVFAAVAVA GLLIMGLHPLIFFLPVRQGANWVVLQTTLIAGLVLTLPLAVVVLLKGKVWTGLLGMFVVVLLVVGAVRLS RPHAPWARWRYTRHPEKMRRALQRERTWRRPVVRIKLWLQYVIAGTPRMPDERAVDAQLDQDVRPAPPPE RTAPILISGSVWSD*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv2180c | - | - | 100% (295) | Probable conserved integral membrane protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2202c | - | 1e-171 | 99.66% (295) | integral membrane protein |
| M. gilvum PYR-GCK | Mflv_2969 | - | 3e-99 | 62.14% (280) | hypothetical protein Mflv_2969 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2491c | - | 1e-38 | 40.84% (262) | hypothetical protein MAB_2491c |
| M. marinum M | MMAR_3224 | - | 1e-134 | 78.75% (287) | hypothetical protein MMAR_3224 |
| M. avium 104 | MAV_2314 | - | 1e-129 | 77.00% (287) | hypothetical protein MAV_2314 |
| M. smegmatis MC2 155 | MSMEG_4246 | - | 1e-102 | 65.57% (273) | integral membrane protein |
| M. thermoresistible (build 8) | TH_1104 | - | 8e-99 | 62.28% (289) | Probable conserved integral membrane protein |
| M. ulcerans Agy99 | MUL_3535 | - | 1e-50 | 77.50% (120) | hypothetical protein MUL_3535 |
| M. vanbaalenii PYR-1 | Mvan_3542 | - | 6e-99 | 62.64% (273) | hypothetical protein Mvan_3542 |
CLUSTAL 2.0.9 multiple sequence alignment
Rv2180c|M.tuberculosis_H37Rv -MEVFHWLQHDI-----VDRGRLPLLCCLVAFVLTFLVTRSFVRFIHRRA
Mb2202c|M.bovis_AF2122/97 -MEVFHWLQHDI-----VDRGRLPLLCCLVAFVLTFLVTRSFVRFIHRRA
MMAR_3224|M.marinum_M ---MFYWLQHDI-----VDRGRLPLLCCLVAFILTFFVTRTFVRVIRGRP
MAV_2314|M.avium_104 MSEVTRWFAHDV-----YDRGHLPLLCCLVAFILTFFVTRSFVRFIRHRA
Mflv_2969|M.gilvum_PYR-GCK ---MRSDLDLDLGFSVHIPSSRLPLVCCLVAFILTFFITRTIVRYIRSQA
Mvan_3542|M.vanbaalenii_PYR-1 ---MRPDLDVELGFSTHLPPSRLPLVCCLVAFILTFFITRTIVRYIRSHA
MSMEG_4246|M.smegmatis_MC2_155 ---MQATVHLDL-----VPRDRLPLVCCLLAFILTFFVTRTVVRYIRSHA
TH_1104|M.thermoresistible__bu ---VFESDRWDF-----ITHDRLPLLFCLIAFILTFLVTRLIVRYIRRHA
MUL_3535|M.ulcerans_Agy99 ---------------------MLPGCLHPDVFCDPHLRARHPRAPRRWPV
MAB_2491c|M.abscessus_ATCC_199 MSWLSTWWRYDV-----VDGYKGPLLLGFVAFVVTFVVTRTITRLIR---
* .* ... :* :
Rv2180c|M.tuberculosis_H37Rv ADGRPARWWQPRNVH-------IGSVHIHHVAFGVVLVMISGLTLVTLSV
Mb2202c|M.bovis_AF2122/97 ADGRPARWWQPRNVH-------IGSVHIHHVAFGVVLVMISGLTLVTLSV
MMAR_3224|M.marinum_M DGGPPPRWWQPRNVH-------LGSVHVHHVTFGVVLVMISGLTLVTLAV
MAV_2314|M.avium_104 ETGRPARWWHPRNVH-------VGGVHIHHVTFGVVLTLLSGLTLVTLSI
Mflv_2969|M.gilvum_PYR-GCK GSDAPRKWWQPRNIS------AGGGLHIHHVVIGVVLVMVSGITMVTIAV
Mvan_3542|M.vanbaalenii_PYR-1 DSDAPRKWWQPHNIS------GGGGLHIHHMVIGVILVMVSGISMVALAV
MSMEG_4246|M.smegmatis_MC2_155 DSDQPRRWWQPRNIA------HG-TMHIHHVVIGVVLVMVSGVTMVTLAV
TH_1104|M.thermoresistible__bu DSDAPRKWWQPRNIAVFTEEGGPGGLHIHHVVLGVVLVLVSGVALVTLSV
MUL_3535|M.ulcerans_Agy99 AQVVAAPQCGPR----------VGACPPCDIRGGAGDDL--GADLGDAGC
MAB_2491c|M.abscessus_ATCC_199 DGKGP-----FHNIS-------GGGVHIHHSTPGVLLLIVGGFTALGSPP
. : . *. : *
Rv2180c|M.tuberculosis_H37Rv DGREPEFTIAASIFGVGAALVLDEYALILHLSDVYWEEDGRTSVDAVFAA
Mb2202c|M.bovis_AF2122/97 DGREPEFTIAASIFGVGAALVLDEYALILHLSDVYWEEDGRTSVDAVFAA
MMAR_3224|M.marinum_M NGREPELSVAATFFGIGAALVLDEYALILHLSDVYWEEDGRTSVDAVFAA
MAV_2314|M.avium_104 NGHEPEFTVAATFFGIGAALVLDEYALILHLSDVYWSEDGRTSVDAVFAA
Mflv_2969|M.gilvum_PYR-GCK DGGVPEFTAASILFGVGAALVLDEFALILHLEDVYWAEDGRTSVDAVFVA
Mvan_3542|M.vanbaalenii_PYR-1 DGGIPEFTAASILFGIGAALVLDEFALILHLSDVYWAEDGRTSVDAVFVA
MSMEG_4246|M.smegmatis_MC2_155 NGGVAEFTVAATFFGIGAALVLDEFALILHLSDVYWSEDGRTSVDAVFAA
TH_1104|M.thermoresistible__bu SGGVPEITVAATFFGIGAALVLDEFALILHLSDVYWTEDGRTSVDAVFVA
MUL_3535|M.ulcerans_Agy99 QRTRARTQRGGNFFGIGAALVLDEYALILHLSDVYWEEDGRTSVDAVFAA
MAB_2491c|M.abscessus_ATCC_199 LS--VWTYLAGLLVGVGASLVLDEFAMIFHLQDVYWTNEGQLSVDMVTLA
.. :.*:**:*****:*:*:**.**** ::*: *** * *
Rv2180c|M.tuberculosis_H37Rv VAVAGLLIMGLHPLIFFLP-VRQGANWVVLQTTLIAGLVLTLPLAVVVLL
Mb2202c|M.bovis_AF2122/97 VAVAGLLIMGLHPLIFFLT-VRQGANWVVLQTTLIAGLVLTLPLAVVVLL
MMAR_3224|M.marinum_M VAVAGLLTLGLHPLMFFPT-IWSGSDSVLPRAVVVGGLVLTLPLATVVLI
MAV_2314|M.avium_104 VAVGGLLIMGLHPLMFFLP-MWHGADSMMLRALVGGAMVLTLPLAVVVVL
Mflv_2969|M.gilvum_PYR-GCK VAVAGLLILGFNPLSFFDVADWQDDPSVTTRAIVVVAALATLALAVIVLL
Mvan_3542|M.vanbaalenii_PYR-1 VAVAGLLILGFNPLSFFDVGIWQNDHSVAARTIVVVAAVLTLALAVIVLL
MSMEG_4246|M.smegmatis_MC2_155 VAVAGLLILGFNPLSFFDVDIWREDPSWLARAAVVLLAVVTLLLAVVVLL
TH_1104|M.thermoresistible__bu VAVAGLLMLGFNPLSFFDVGMWRDDESVAARLTVIALALVTLMLAVVVLL
MUL_3535|M.ulcerans_Agy99 VAVAGLLTLGLHPLMFFPT-IWSGSDSVLPRAVVVGGLVLTLPLATVVLI
MAB_2491c|M.abscessus_ATCC_199 TACISLAAVGVSPLNVDGL----TGVIAIARGVAMLLLLVHLALVAVTAL
.* .* :*. ** . : : * *..:. :
Rv2180c|M.tuberculosis_H37Rv KGKVWTGLLGMFVVVLLVVGAVRLSRPHAPWARWRYTRHPEKMRRALQRE
Mb2202c|M.bovis_AF2122/97 KGKVWTGLLGMFVVVLLVVGAVRLSRPHAPWARWRYTRHPEKMRRALQRE
MMAR_3224|M.marinum_M KGKVWTGLLGMFIVVLLVIGAIRLSRPHAPWARWRYTAKPDKMRRALQRE
MAV_2314|M.avium_104 KGKVWTGLLGMFLVVLLVIGAVRLSRPHAPWARWRYSTQPEKMRRALQRE
Mflv_2969|M.gilvum_PYR-GCK KGKVWTGLVGMFITPLLVIGAVRLSRPHAPWARWRYTSRPRKMHRALERE
Mvan_3542|M.vanbaalenii_PYR-1 KGKVWTGLVGMFITPLLFVGAIRLSRPHAPWARWRYTKRPRKMHRALERE
MSMEG_4246|M.smegmatis_MC2_155 KGKVWTGLVGMFITPLLVIGAIRLSRPHAPWARWRYTKRPRKMHRALERE
TH_1104|M.thermoresistible__bu KGKVWTGLVGMFITPLLVIGAIRLSRPHAPWARWRYTGRPRKMHRALLRE
MUL_3535|M.ulcerans_Agy99 KGKVWTGLLGMFIVVLLVIGAIRLSRPHAPWAPVALYRETGQDAASVAAR
MAB_2491c|M.abscessus_ATCC_199 KGKYPTAMLGIFLAPIAWVAAFRLARPTSPWARWRYS--PRRLTRARQRA
*** *.::*:*:. : :.*.**:** :*** . : :
Rv2180c|M.tuberculosis_H37Rv RTWRRPVVRIKLWLQYVIAGTPRMPDERAVDAQLDQDVRPAPPPER----
Mb2202c|M.bovis_AF2122/97 RTWRRPVVRIKLWLQYVIAGTPRMPDERAVDAQLDQDVRPAPPPER----
MMAR_3224|M.marinum_M RTLRRPVVRAKLWLQCAIAGTPRLPDERAVEAQLDRDVHPAPPPEG----
MAV_2314|M.avium_104 RTLRRPVVRAKLYLQCAIAGTPRFPDERTVDATLDHEVHPAPAP------
Mflv_2969|M.gilvum_PYR-GCK RWLRRPVVQAKLWLQDAIAGMPKFPDDALVDEQLDREIHAAPAPAE----
Mvan_3542|M.vanbaalenii_PYR-1 RWLRRPVVQAKLWLQDAIAGMPKFPDDALVDEQLDREIHAAPAPGN----
MSMEG_4246|M.smegmatis_MC2_155 RWLRRPVVQAKLWLQDAITGMPRFPDDAAVDEQLDREIHAAPAPGAGIDA
TH_1104|M.thermoresistible__bu RRVRRPVVQAKIWFQDAIAGMPRFPDDAKVDEQLDREIRAAPAPPD----
MUL_3535|M.ulcerans_Agy99 AHLAPPGGAGQALVAVCDRRHPSAARRARRRGAVGSRRSPRAATRG----
MAB_2491c|M.abscessus_ATCC_199 LGFDHRWGPVRRHWLDAIGGTPTP---ELPQPPTDSRTR-----------
: * .
Rv2180c|M.tuberculosis_H37Rv ---------TAPILISGSVWSD-------------
Mb2202c|M.bovis_AF2122/97 ---------TAPILISGSVWSD-------------
MMAR_3224|M.marinum_M ---------TEPILTS--V----------------
MAV_2314|M.avium_104 ---------TGPILIGR------------------
Mflv_2969|M.gilvum_PYR-GCK ---------REPAPQKAS-----------------
Mvan_3542|M.vanbaalenii_PYR-1 ---------PEPVTQKAS-----------------
MSMEG_4246|M.smegmatis_MC2_155 KIEARIEARTERTRRTGSCGTSTTPSSSTTDARST
TH_1104|M.thermoresistible__bu ---------RAGATSMRS-----------------
MUL_3535|M.ulcerans_Agy99 --------HRADIDLRIGCGDAVLL----------
MAB_2491c|M.abscessus_ATCC_199 -----------------------------------