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LPGCLHPDVFCDPHLRARHPRAPRRWPVAQVVAAPQCGPRVGACPPCDIRGGAGDDLGADLGDAGCQRTR ARTQRGGNFFGIGAALVLDEYALILHLSDVYWEEDGRTSVDAVFAAVAVAGLLTLGLHPLMFFPTIWSGS DSVLPRAVVVGGLVLTLPLATVVLIKGKVWTGLLGMFIVVLLVIGAIRLSRPHAPWAPVALYRETGQDAA SVAARAHLAPPGGAGQALVAVCDRRHPSAARRARRRGAVGSRRSPRAATRGHRADIDLRIGCGDAVLL*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_3535 | - | - | 100% (279) | hypothetical protein MUL_3535 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2202c | - | 2e-51 | 78.33% (120) | integral membrane protein |
| M. gilvum PYR-GCK | Mflv_2969 | - | 1e-43 | 72.27% (119) | hypothetical protein Mflv_2969 |
| M. tuberculosis H37Rv | Rv2180c | - | 1e-50 | 77.50% (120) | integral membrane protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2491c | - | 7e-20 | 40.94% (127) | hypothetical protein MAB_2491c |
| M. marinum M | MMAR_3224 | - | 1e-63 | 100.00% (119) | hypothetical protein MMAR_3224 |
| M. avium 104 | MAV_2314 | - | 3e-53 | 82.35% (119) | hypothetical protein MAV_2314 |
| M. smegmatis MC2 155 | MSMEG_4246 | - | 4e-47 | 51.79% (224) | integral membrane protein |
| M. thermoresistible (build 8) | TH_1104 | - | 8e-45 | 70.77% (130) | Probable conserved integral membrane protein |
| M. vanbaalenii PYR-1 | Mvan_3542 | - | 9e-45 | 74.79% (119) | hypothetical protein Mvan_3542 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2969|M.gilvum_PYR-GCK ---MRSDLDLDLGFSVHIPSSRLPLVCCLVAFILTFFITRTIVRYIRSQA
Mvan_3542|M.vanbaalenii_PYR-1 ---MRPDLDVELGFSTHLPPSRLPLVCCLVAFILTFFITRTIVRYIRSHA
MSMEG_4246|M.smegmatis_MC2_155 ---MQATVHLDL-----VPRDRLPLVCCLLAFILTFFVTRTVVRYIRSHA
TH_1104|M.thermoresistible__bu ---VFESDRWDF-----ITHDRLPLLFCLIAFILTFLVTRLIVRYIRRHA
Mb2202c|M.bovis_AF2122/97 -MEVFHWLQHDI-----VDRGRLPLLCCLVAFVLTFLVTRSFVRFIHRRA
Rv2180c|M.tuberculosis_H37Rv -MEVFHWLQHDI-----VDRGRLPLLCCLVAFVLTFLVTRSFVRFIHRRA
MMAR_3224|M.marinum_M ---MFYWLQHDI-----VDRGRLPLLCCLVAFILTFFVTRTFVRVIRGRP
MAV_2314|M.avium_104 MSEVTRWFAHDV-----YDRGHLPLLCCLVAFILTFFVTRSFVRFIRHRA
MUL_3535|M.ulcerans_Agy99 ---------------------MLPGCLHPDVFCDPHLRARHPRAPRRWPV
MAB_2491c|M.abscessus_ATCC_199 MSWLSTWWRYDV-----VDGYKGPLLLGFVAFVVTFVVTRTITRLIR---
* .* ... :* :
Mflv_2969|M.gilvum_PYR-GCK GSDAPRKWWQPRNIS------AGGGLHIHHVVIGVVLVMVSGITMVTIAV
Mvan_3542|M.vanbaalenii_PYR-1 DSDAPRKWWQPHNIS------GGGGLHIHHMVIGVILVMVSGISMVALAV
MSMEG_4246|M.smegmatis_MC2_155 DSDQPRRWWQPRNIA------HG-TMHIHHVVIGVVLVMVSGVTMVTLAV
TH_1104|M.thermoresistible__bu DSDAPRKWWQPRNIAVFTEEGGPGGLHIHHVVLGVVLVLVSGVALVTLSV
Mb2202c|M.bovis_AF2122/97 ADGRPARWWQPRNVH-------IGSVHIHHVAFGVVLVMISGLTLVTLSV
Rv2180c|M.tuberculosis_H37Rv ADGRPARWWQPRNVH-------IGSVHIHHVAFGVVLVMISGLTLVTLSV
MMAR_3224|M.marinum_M DGGPPPRWWQPRNVH-------LGSVHVHHVTFGVVLVMISGLTLVTLAV
MAV_2314|M.avium_104 ETGRPARWWHPRNVH-------VGGVHIHHVTFGVVLTLLSGLTLVTLSI
MUL_3535|M.ulcerans_Agy99 AQVVAAPQCGPR----------VGACPPCDIRGGAGDDL--GADLGDAGC
MAB_2491c|M.abscessus_ATCC_199 DGKGP-----FHNIS-------GGGVHIHHSTPGVLLLIVGGFTALGSPP
. : . *. : *
Mflv_2969|M.gilvum_PYR-GCK DGGVPEFTAASILFGVGAALVLDEFALILHLEDVYWAEDGRTSVDAVFVA
Mvan_3542|M.vanbaalenii_PYR-1 DGGIPEFTAASILFGIGAALVLDEFALILHLSDVYWAEDGRTSVDAVFVA
MSMEG_4246|M.smegmatis_MC2_155 NGGVAEFTVAATFFGIGAALVLDEFALILHLSDVYWSEDGRTSVDAVFAA
TH_1104|M.thermoresistible__bu SGGVPEITVAATFFGIGAALVLDEFALILHLSDVYWTEDGRTSVDAVFVA
Mb2202c|M.bovis_AF2122/97 DGREPEFTIAASIFGVGAALVLDEYALILHLSDVYWEEDGRTSVDAVFAA
Rv2180c|M.tuberculosis_H37Rv DGREPEFTIAASIFGVGAALVLDEYALILHLSDVYWEEDGRTSVDAVFAA
MMAR_3224|M.marinum_M NGREPELSVAATFFGIGAALVLDEYALILHLSDVYWEEDGRTSVDAVFAA
MAV_2314|M.avium_104 NGHEPEFTVAATFFGIGAALVLDEYALILHLSDVYWSEDGRTSVDAVFAA
MUL_3535|M.ulcerans_Agy99 QRTRARTQRGGNFFGIGAALVLDEYALILHLSDVYWEEDGRTSVDAVFAA
MAB_2491c|M.abscessus_ATCC_199 LS--VWTYLAGLLVGVGASLVLDEFAMIFHLQDVYWTNEGQLSVDMVTLA
.. :.*:**:*****:*:*:**.**** ::*: *** * *
Mflv_2969|M.gilvum_PYR-GCK VAVAGLLILGFNPLSFFDVADWQDDPSVTTRAIVVVAALATLALAVIVLL
Mvan_3542|M.vanbaalenii_PYR-1 VAVAGLLILGFNPLSFFDVGIWQNDHSVAARTIVVVAAVLTLALAVIVLL
MSMEG_4246|M.smegmatis_MC2_155 VAVAGLLILGFNPLSFFDVDIWREDPSWLARAAVVLLAVVTLLLAVVVLL
TH_1104|M.thermoresistible__bu VAVAGLLMLGFNPLSFFDVGMWRDDESVAARLTVIALALVTLMLAVVVLL
Mb2202c|M.bovis_AF2122/97 VAVAGLLIMGLHPLIFFLT-VRQGANWVVLQTTLIAGLVLTLPLAVVVLL
Rv2180c|M.tuberculosis_H37Rv VAVAGLLIMGLHPLIFFLP-VRQGANWVVLQTTLIAGLVLTLPLAVVVLL
MMAR_3224|M.marinum_M VAVAGLLTLGLHPLMFFPT-IWSGSDSVLPRAVVVGGLVLTLPLATVVLI
MAV_2314|M.avium_104 VAVGGLLIMGLHPLMFFLP-MWHGADSMMLRALVGGAMVLTLPLAVVVVL
MUL_3535|M.ulcerans_Agy99 VAVAGLLTLGLHPLMFFPT-IWSGSDSVLPRAVVVGGLVLTLPLATVVLI
MAB_2491c|M.abscessus_ATCC_199 TACISLAAVGVSPLNVDGL----TGVIAIARGVAMLLLLVHLALVAVTAL
.* .* :*. ** . : : * *..:. :
Mflv_2969|M.gilvum_PYR-GCK KGKVWTGLVGMFITPLLVIGAVRLSRPHAPWARWRYTSRPRKMHRALERE
Mvan_3542|M.vanbaalenii_PYR-1 KGKVWTGLVGMFITPLLFVGAIRLSRPHAPWARWRYTKRPRKMHRALERE
MSMEG_4246|M.smegmatis_MC2_155 KGKVWTGLVGMFITPLLVIGAIRLSRPHAPWARWRYTKRPRKMHRALERE
TH_1104|M.thermoresistible__bu KGKVWTGLVGMFITPLLVIGAIRLSRPHAPWARWRYTGRPRKMHRALLRE
Mb2202c|M.bovis_AF2122/97 KGKVWTGLLGMFVVVLLVVGAVRLSRPHAPWARWRYTRHPEKMRRALQRE
Rv2180c|M.tuberculosis_H37Rv KGKVWTGLLGMFVVVLLVVGAVRLSRPHAPWARWRYTRHPEKMRRALQRE
MMAR_3224|M.marinum_M KGKVWTGLLGMFIVVLLVIGAIRLSRPHAPWARWRYTAKPDKMRRALQRE
MAV_2314|M.avium_104 KGKVWTGLLGMFLVVLLVIGAVRLSRPHAPWARWRYSTQPEKMRRALQRE
MUL_3535|M.ulcerans_Agy99 KGKVWTGLLGMFIVVLLVIGAIRLSRPHAPWAPVALYRETGQDAASVAAR
MAB_2491c|M.abscessus_ATCC_199 KGKYPTAMLGIFLAPIAWVAAFRLARPTSPWARWRYS--PRRLTRARQRA
*** *.::*:*:. : :.*.**:** :*** . : :
Mflv_2969|M.gilvum_PYR-GCK RWLRRPVVQAKLWLQDAIAGMPKFPDDALVDEQLDREIHAAPAPAE----
Mvan_3542|M.vanbaalenii_PYR-1 RWLRRPVVQAKLWLQDAIAGMPKFPDDALVDEQLDREIHAAPAPGN----
MSMEG_4246|M.smegmatis_MC2_155 RWLRRPVVQAKLWLQDAITGMPRFPDDAAVDEQLDREIHAAPAPGAGIDA
TH_1104|M.thermoresistible__bu RRVRRPVVQAKIWFQDAIAGMPRFPDDAKVDEQLDREIRAAPAPPD----
Mb2202c|M.bovis_AF2122/97 RTWRRPVVRIKLWLQYVIAGTPRMPDERAVDAQLDQDVRPAPPPER----
Rv2180c|M.tuberculosis_H37Rv RTWRRPVVRIKLWLQYVIAGTPRMPDERAVDAQLDQDVRPAPPPER----
MMAR_3224|M.marinum_M RTLRRPVVRAKLWLQCAIAGTPRLPDERAVEAQLDRDVHPAPPPEG----
MAV_2314|M.avium_104 RTLRRPVVRAKLYLQCAIAGTPRFPDERTVDATLDHEVHPAPAP------
MUL_3535|M.ulcerans_Agy99 AHLAPPGGAGQALVAVCDRRHPSAARRARRRGAVGSRRSPRAATRG----
MAB_2491c|M.abscessus_ATCC_199 LGFDHRWGPVRRHWLDAIGGTPTP---ELPQPPTDSRTR-----------
: * .
Mflv_2969|M.gilvum_PYR-GCK ---------REPAPQKAS-----------------
Mvan_3542|M.vanbaalenii_PYR-1 ---------PEPVTQKAS-----------------
MSMEG_4246|M.smegmatis_MC2_155 KIEARIEARTERTRRTGSCGTSTTPSSSTTDARST
TH_1104|M.thermoresistible__bu ---------RAGATSMRS-----------------
Mb2202c|M.bovis_AF2122/97 ---------TAPILISGSVWSD-------------
Rv2180c|M.tuberculosis_H37Rv ---------TAPILISGSVWSD-------------
MMAR_3224|M.marinum_M ---------TEPILTS--V----------------
MAV_2314|M.avium_104 ---------TGPILIGR------------------
MUL_3535|M.ulcerans_Agy99 --------HRADIDLRIGCGDAVLL----------
MAB_2491c|M.abscessus_ATCC_199 -----------------------------------