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M. tuberculosis H37Rv Rv2175c (-)

annotation: conserved hypothetical regulatory protein
coordinates: 2437446 - 2437886
length: 146

PGRAPGSTLARVGSIPAGDDVLDPDEPTYDLPRVAELLGVPVSKVAQQLREGHLVAVRRAGGVVIPQVFF
TNSGQVVKSLPGLLTILHDGGYRDTEIMRWLFTPDPSLTITRDGSRDAVSNARPVDALHAHQAREVVRRA
QAMAY*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv2175c--100% (146)conserved hypothetical regulatory protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2197c-8e-8099.32% (146) putative regulatory protein
M. gilvum PYR-GCKMflv_2973-5e-3971.29% (101) hypothetical protein Mflv_2973
M. leprae Br4923MLBr_00898-6e-6282.09% (134) putative DNA-binding protein
M. abscessus ATCC 19977MAB_1990-2e-4058.21% (134) hypothetical protein MAB_1990
M. marinum MMMAR_3210-1e-6994.03% (134) regulatory protein
M. avium 104MAV_2320-3e-6188.80% (125) hypothetical protein MAV_2320
M. smegmatis MC2 155MSMEG_4242-2e-5573.13% (134) transcriptional regulatory protein
M. thermoresistible (build 8)TH_0710-6e-5776.12% (134) conserved hypothetical regulatory protein
M. ulcerans Agy99MUL_3518-1e-6994.03% (134) regulatory protein
M. vanbaalenii PYR-1Mvan_3538-1e-5370.21% (141) hypothetical protein Mvan_3538

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_2973|M.gilvum_PYR-GCK          ---------------------------------------------MHQHL
Mvan_3538|M.vanbaalenii_PYR-1       ---MQPSPRLSAMSSIPTSEDVLESDEAVYDLPTVARLLGMPVTKVHQQL
MSMEG_4242|M.smegmatis_MC2_155      ------------MSSIPAADDVLDPDEAVYDLPTVADILGIPVTKVHQQL
Rv2175c|M.tuberculosis_H37Rv        MPGRAPGSTLARVGSIPAGDDVLDPDEPTYDLPRVAELLGVPVSKVAQQL
Mb2197c|M.bovis_AF2122/97           MPGRAPGSTLARVGSILAGDDVLDPDEPTYDLPRVAELLGVPVSKVAQQL
MMAR_3210|M.marinum_M               ------------MGSIPAGDDVLDPDEPTYDLSRVAELLGVPVSKVHQQL
MUL_3518|M.ulcerans_Agy99           ------------MGSIPAGDDVLDPDEPTYDLSRVAELLGVPVSKVHQQL
MAV_2320|M.avium_104                ---------------------MLDPDEPIYDLPRVAELLGVPVTKVHQQL
MLBr_00898|M.leprae_Br4923          ------------MGSIPAGDDVLDPDEPTYDLTQVAELLGIPVSRVHRKL
TH_0710|M.thermoresistible__bu      ------------MSSVPAADDVLDPDEPVYRLAEVAELLGIPVTKVQQQL
MAB_1990|M.abscessus_ATCC_1997      ------------MSAIPYVADTLDADEPLFTLKEVAARLRVPVSKVQQYL
                                                                                 : : *

Mflv_2973|M.gilvum_PYR-GCK          RDGHLIAVRRNRSIVVPKAFFDDHGHVVKSLPGLLVVLHDGGYTETEIVR
Mvan_3538|M.vanbaalenii_PYR-1       REGHLVAVRRGGTIVVPKVFFDDSGHVVKSLSGLLVVLRDGGYTETEIVR
MSMEG_4242|M.smegmatis_MC2_155      RDGHLVAVRRNGVIAVPKIFFDDAGHVVKSLPGLLVVLRDGGYRTNEILR
Rv2175c|M.tuberculosis_H37Rv        REGHLVAVRRAGGVVIPQVFFTNSGQVVKSLPGLLTILHDGGYRDTEIMR
Mb2197c|M.bovis_AF2122/97           REGHLVAVRRAGGVVIPQVFFTNSGQVVKSLPGLLTILHDGGYRDTEIMR
MMAR_3210|M.marinum_M               REGHLVAVRREGGVVVPQVFFTSSGQVVKSLPGLLTILHDGGYHDTEIIR
MUL_3518|M.ulcerans_Agy99           REGHLVAVRREGGVVVPQVFFTSSGQVVKSLPGLLTILHDGGYHDTEIIR
MAV_2320|M.avium_104                REGHLVAVRRGEALVVPQVFFTKSGEVVKSLPGLLTILHDGGYRDTEIVR
MLBr_00898|M.leprae_Br4923          CEGYLVAVRRGDSLVVPQIFFTNSGAVVKSLPGLLTILHDGSFHETEIVR
TH_0710|M.thermoresistible__bu      RDGQLVAVRRDGAPVIPKIFFDDDGQVVKNLPGLLIVLRDGGYRETEIVR
MAB_1990|M.abscessus_ATCC_1997      RDGELIAVKRDGEIKVPVIFFSPEGPVVKHLFGLLSVLRDGGYHEPEILR
                                     :* *:**:*     :*  **   * *** * *** :*:**.:   **:*

Mflv_2973|M.gilvum_PYR-GCK          WLFTPDPSLAIRRDGAGEEQANARPVDALHSHQAREVVRRAQAMAY
Mvan_3538|M.vanbaalenii_PYR-1       WLFTPDASLTIRRDGSTEGQANARPVDALHSHQAREVVRRAQAMAY
MSMEG_4242|M.smegmatis_MC2_155      WLFTPDESLTITRDGSTERLTNARPVDALHSHQAREVIRRAQAMAY
Rv2175c|M.tuberculosis_H37Rv        WLFTPDPSLTITRDGSRDAVSNARPVDALHAHQAREVVRRAQAMAY
Mb2197c|M.bovis_AF2122/97           WLFTPDPSLTITRDGSRDAVSNARPVDALHAHQAREVVRRAQAMAY
MMAR_3210|M.marinum_M               WLFTPDPSLTVTRDGSRDAVSNARPVDALHAHQAREVVRRAQAMAY
MUL_3518|M.ulcerans_Agy99           WLFTPDPSLTVTRDGSRDAVSNARPVDALHAHQAREVVRRAQAMAY
MAV_2320|M.avium_104                WLFTRDPSLTVTRDGSRDAISNARPVDALHAHQAREVVRRAQAMAY
MLBr_00898|M.leprae_Br4923          WLFTPDPSLTLTRDGSRDVVSNARPVDALHTHQAREVVRRAQAMAY
TH_0710|M.thermoresistible__bu      WLFTPDPSLTITRDGSREPLSNVRPVDALHSHQAREVVRRAQAMAY
MAB_1990|M.abscessus_ATCC_1997      WLFAGDESLTVSRDGTTERIEAARPVDALHGHQAREVLRRAQAMAY
                                    ***: * **:: ***: :    .******* ******:********