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M. tuberculosis H37Rv Rv2171 (lppM)

annotation: Probable conserved lipoprotein lppM
coordinates: 2432951 - 2433634
length: 227

VARTRRRGMLAIAMLLMLVPLATGCLRVRASITISPDDLVSGEIIAAAKPKNSKDTGPALDGDVPFSQKV
AVSNYDSDGYVGSQAVFSDLTFAELPQLANMNSDAAGVNLSLRRNGNIVILEGRADLTSVSDPDADVELT
VAFPAAVTSTNGDRIEPEVVQWKLKPGVVSTMSAQARYTDPNTRSFTGAGIWLGIAAFAAAGVVAVLAWI
DRDRSPRLTASGDPPTS
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv2171lppM-100% (227)Probable conserved lipoprotein lppM

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2193lppM1e-126100.00% (227) lipoprotein lppM
M. gilvum PYR-GCKMflv_2976-2e-8167.91% (215) LppM
M. leprae Br4923MLBr_00902-8e-9275.45% (224) putative lipoprotein
M. abscessus ATCC 19977MAB_1994c-5e-6754.71% (223) lipoprotein LppM
M. marinum MMMAR_3206lppM1e-10887.61% (226) lipoprotein LppM
M. avium 104MAV_2323-1e-10584.23% (222) LppM protein
M. smegmatis MC2 155MSMEG_4239-2e-7864.35% (216) LppM protein
M. thermoresistible (build 8)TH_0707lppM6e-7965.71% (210) Probable conserved lipoprotein lppM
M. ulcerans Agy99MUL_3514lppM1e-10387.44% (215) lipoprotein LppM
M. vanbaalenii PYR-1Mvan_3535-9e-8164.86% (222) LppM

CLUSTAL 2.0.9 multiple sequence alignment


Rv2171|M.tuberculosis_H37Rv         --------------MARTRRRGMLAIAMLLM-LVPLATGCLRVRASITIS
Mb2193|M.bovis_AF2122/97            --------------MARTRRRGMLAIAMLLM-LVPLATGCLRVRASITIS
MMAR_3206|M.marinum_M               MRASSPPLSAPAAPALRARRRRLLAIAMLLM-LVPLATGCLRVRASITIS
MUL_3514|M.ulcerans_Agy99           ---------------------------MLLM-LVPLATGCLRVRASITIS
MAV_2323|M.avium_104                -----------------MRRRRLLAFAMLLL-VVPLATGCLRVRASLTIS
MLBr_00902|M.leprae_Br4923          MRARFPPLFTRG---CTAQRRRTLTIALLLVAMVPLATGCLRVTASITIS
Mflv_2976|M.gilvum_PYR-GCK          ----------MLTR--HRTRRRLLAMVLLLLVVAPSLIGCVRVRASITVS
Mvan_3535|M.vanbaalenii_PYR-1       ----------MLNR--HRARRRLFALVLLLLVVAPSLIGCVRIRASITVS
MSMEG_4239|M.smegmatis_MC2_155      ----------MRVRRPSRSRRRLLVLVMLLLLVLPTAVGCVRIRASITVS
TH_0707|M.thermoresistible__bu      -----------------------VIAVLALLLMLPALVGCVRVRASITVS
MAB_1994c|M.abscessus_ATCC_199      ---------------MTRRGRVARITAVLLLATLPLLSGCVRVKASMTVT
                                                               : *:   *   **:*: **:*::

Rv2171|M.tuberculosis_H37Rv         PDDLVSGEIIAAAKPKNSKDTGPALDGD-VPFSQKVAVSNYDSDGYVGSQ
Mb2193|M.bovis_AF2122/97            PDDLVSGEIIAAAKPKNSKDTGPALDGD-VPFSQKVAVSNYDSDGYVGSQ
MMAR_3206|M.marinum_M               PEDLVSGEIIAAAKPKNNKDTGPQLDSDNVAFSQKVAVSNYDSDGYVGSQ
MUL_3514|M.ulcerans_Agy99           PEDLVSGEIIAAAKPKNNKDTGPQLDSDNVAFSQKVAVSNYDGDGYVGSQ
MAV_2323|M.avium_104                PDDLVSGEIVAAAKPKTPKDTGPQLDSNNLPFSQKVAVSNYDSDGYVGSQ
MLBr_00902|M.leprae_Br4923          PDNLVSGKIIAAAKPKNKNDAGPQLNDN-LPFSQKIAVSNYNSDGYVGSQ
Mflv_2976|M.gilvum_PYR-GCK          PDDRVSGQIVAAAIPRDDNDKGPQLLNN-LPFAQKVAVSDYSRDDYVGSQ
Mvan_3535|M.vanbaalenii_PYR-1       PDDRVSGQIVAAAIPRDDNDKGPQLLNN-LPFAQKVAVSDYSRDDYVGSQ
MSMEG_4239|M.smegmatis_MC2_155      PDDRVSGQIIAAAKPSDADDKGPQLVNN-LPFAHKVAVSEYSRDDYVGSQ
TH_0707|M.thermoresistible__bu      PDDRVSGQIIAAAKVEDPADEGPQLVNS-LPFANKVSVSRYERDDYVGTQ
MAB_1994c|M.abscessus_ATCC_199      TDDHVSGQLIAVAKPQGKNDKGPQLDRN-MSFAEKVQVSEYEENGMVGSR
                                    .:: ***:::*.*      * ** *  . :.*:.*: ** *. :. **::

Rv2171|M.tuberculosis_H37Rv         AVFSDLTFAELPQLANMNSDAAGVNLSLRRNGNIVILEGRADLTSVSD-P
Mb2193|M.bovis_AF2122/97            AVFSDLTFAELPQLANMNSDAAGVNLSLRRNGNIVILEGRADLTSVSD-P
MMAR_3206|M.marinum_M               AVFSDLTFAELPQLANMNPDAAGVNLSLRRNGNMVILEGRVDLTSVTD-A
MUL_3514|M.ulcerans_Agy99           AVFSDLTFAELPQLANMNPDAAGVNLSLRRNGNMVILEGRVDLTSVTD-A
MAV_2323|M.avium_104                AVFSDLTFAELPQLANMNSDAAGVNLSLRRNGNLVLLEGRADLTSLTD-P
MLBr_00902|M.leprae_Br4923          AVFSDLTFAELPQLANMNSSTTDVTLSLRRNGNLVILESRADLTSVTD-P
Mflv_2976|M.gilvum_PYR-GCK          ATFSDLTFAELPQLAAMNRDAAGVDISLRRAGDLVILEGRVDLTSLSD-P
Mvan_3535|M.vanbaalenii_PYR-1       AVFSDLTFAELPQLASMNRDAAGVDISLRRAGDLVILEGRADLTSLSD-P
MSMEG_4239|M.smegmatis_MC2_155      AVFSDLSFAEVPQLAALSRDAAGVDISLRRAGDLVILEGRVDLTSMND-P
TH_0707|M.thermoresistible__bu      ATFSGLTFAELPQLANLNREAAGMDLSLRRAGNVVILEGRVDLTTLND-P
MAB_1994c|M.abscessus_ATCC_199      AIFNDLTFSEVPQLAGMNKNAAGFDLTLRRNGDVVVLEGRADLTALGDNS
                                    * *..*:*:*:**** :. .::.. ::*** *::*:**.*.***:: * .

Rv2171|M.tuberculosis_H37Rv         DADVELTVAFPAAVTSTNGDRIEPEVVQWKLKPGVVSTMSAQARYTDPNT
Mb2193|M.bovis_AF2122/97            DADVELTVAFPAAVTSTNGDRIEPEVVQWKLKPGVVSTMSAQARYTDPNT
MMAR_3206|M.marinum_M               DAEVELTVAFPGTVTSTNGDRIEPEVVQWKLKPGVVSTMNAQARYTDPNT
MUL_3514|M.ulcerans_Agy99           DAEVELTVAFPGTVTSTNGDRIEPEVVQWKLKPGVVSTMNAQARYTDPNT
MAV_2323|M.avium_104                EADVELTVAFPGVVTSTNGDRVEPDVVSWKLKPGVVSTMTAQARYTDPNT
MLBr_00902|M.leprae_Br4923          DADVELTVAFPGVVTSTNGDRIETKVVAWKLKPGVVSTMSARARYTDPDT
Mflv_2976|M.gilvum_PYR-GCK          EADVSLSVAFPGEVTSTNGDQISSSVVEWKLRPGVVSTMNAQARYTDPSA
Mvan_3535|M.vanbaalenii_PYR-1       EADVSLSVAFPGEVTSTNGEQISSSVVEWKLRPGVVSTMNAQARYTDPSA
MSMEG_4239|M.smegmatis_MC2_155      EADVLLTVSFPGDVTSTNGDQVTSSIVEWKLRPGVVSTMNAQARYTDPSA
TH_0707|M.thermoresistible__bu      QADVSLTVSFPGEVTSTNGNRISAEIVEWKLRPGVVSTMSAQARYTDPST
MAB_1994c|M.abscessus_ATCC_199      NADVSLAVSFPGDIESTNGEMLGSDSVQWKLNPGVVSSFTATARYTDPST
                                    :*:* *:*:**. : ****: : .. * ***.*****::.* ******.:

Rv2171|M.tuberculosis_H37Rv         RSFTGAGIWLGIAAFAAAGVVAVLAWIDRDRSPRLTASGDPPTS-
Mb2193|M.bovis_AF2122/97            RSFTGAGIWLGIAAFAAAGVVAVLAWIDRDRSPRLTASGDPPTS-
MMAR_3206|M.marinum_M               RSFTAAGIWLAIASFAAAGVVAALAWVSRDRSPRFTAPGDQPPS-
MUL_3514|M.ulcerans_Agy99           RSFTAAGIWLAIASFAAAGAVAALAWVSRDRSPRFTAPGDQPPS-
MAV_2323|M.avium_104                RSFTGAVVWLGIASFAAAGVVGLLAWVSRDRSPRLTAPRDQPPPE
MLBr_00902|M.leprae_Br4923          RSFTGAAVWLGIASFSAASVVVLLAWNERKSSARLQIPRDSSSS-
Mflv_2976|M.gilvum_PYR-GCK          RSFAGAAIWLGVASFLVAGIVAWLAYSNRDRSPRPGEPQEQTH--
Mvan_3535|M.vanbaalenii_PYR-1       RSFTGAAIWLGMASLVVAGIIGWLAYSNRDRSPRPGETQEPTR--
MSMEG_4239|M.smegmatis_MC2_155      RSFTTAAIWLVIAAFVVASVVAGLAYVSRDQSPKPGEPAPTET--
TH_0707|M.thermoresistible__bu      RSFVKAAIWLGVVSFAVAAVIAVLAWRSRDRSPKVWEIQPQDS--
MAB_1994c|M.abscessus_ATCC_199      RSFNGAAIFVSIAALLVGALVASMAWLDRDQSPRFTPEQFPE---
                                    ***  * ::: :.:: ... :  :*: .*. *.: