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LRVAVPNKGALSEPATEILAEAGYRRRTDSKDLTVIDPVNNVEFFFLRPKDIAIYVGSGELDFGITGRDL VCDSGAQVRERLALGFGSSSFRYAAPAGRNWTTADLAGMRIATAYPNLVRKDLATKGIEATVIRLDGAVE ISVQLGVADAIADVVGSGRTLSQHDLVAFGEPLCDSEAVLIERAGTDGQDQTEARDQLVARVQGVVFGQQ YLMLDYDCPRSALKKATAITPGLESPTIAPLADPDWVAIRALVPRRDVNGIMDELAAIGAKAILASDIRF CRF*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv2121c | hisG | - | 100% (284) | ATP phosphoribosyltransferase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2145c | hisG | 1e-160 | 100.00% (284) | ATP phosphoribosyltransferase |
| M. gilvum PYR-GCK | Mflv_3057 | hisG | 1e-132 | 83.45% (284) | ATP phosphoribosyltransferase |
| M. leprae Br4923 | MLBr_01310 | hisG | 1e-138 | 87.80% (287) | ATP phosphoribosyltransferase |
| M. abscessus ATCC 19977 | MAB_2132 | hisG | 1e-121 | 77.66% (282) | ATP phosphoribosyltransferase |
| M. marinum M | MMAR_3103 | hisG | 1e-142 | 90.49% (284) | ATP phosphoribosyltransferase HisG |
| M. avium 104 | MAV_2393 | hisG | 1e-139 | 89.82% (285) | ATP phosphoribosyltransferase |
| M. smegmatis MC2 155 | MSMEG_4180 | hisG | 1e-136 | 84.15% (284) | ATP phosphoribosyltransferase |
| M. thermoresistible (build 8) | TH_0037 | hisG | 1e-131 | 82.39% (284) | Probable ATP phosphoribosyltransferase HisG |
| M. ulcerans Agy99 | MUL_2352 | hisG | 1e-141 | 89.79% (284) | ATP phosphoribosyltransferase |
| M. vanbaalenii PYR-1 | Mvan_3470 | hisG | 1e-131 | 84.10% (283) | ATP phosphoribosyltransferase |
CLUSTAL 2.0.9 multiple sequence alignment
Rv2121c|M.tuberculosis_H37Rv ------MLRVAVPNKGALSEPATEILAEAGYRRRTDSKDLTVIDPVNNVE
Mb2145c|M.bovis_AF2122/97 ------MLRVAVPNKGALSEPATEILAEAGYRRRTDSKDLTVIDPVNNVE
MMAR_3103|M.marinum_M ----MSMLRVAVPNKGALSEPATEILAEAGYRRRTDPKDLTVIDPANNVE
MUL_2352|M.ulcerans_Agy99 ----MSMLRVAVPNKGALSEPATEILAEAGYRRRTDPKDLTVIDPANNVE
MLBr_01310|M.leprae_Br4923 ----MSMLRVAVPNKGALSEPATEILAEAGYRRRTDPKDLTVVDPVNRVE
MAV_2393|M.avium_104 ------MLRVAVPNKGTLSEPATEILAEAGYRRRTDSKDLTVIDPVNQVE
MSMEG_4180|M.smegmatis_MC2_155 --MTDQMLRVAVPNKGALSESAAEILAEAGYRRRRDPKDLTVVDPGNNVE
TH_0037|M.thermoresistible__bu -----VMLRIAMPNKGTLSEPAAEILAEAGYRRRSDTKDLTVVDPVNEVE
Mflv_3057|M.gilvum_PYR-GCK ------MLRVAVPNKGALSESASEILSEAGYRRRSDPKDLTVVDPANNVE
Mvan_3470|M.vanbaalenii_PYR-1 -MSAPKTLRVAVPNKGALSESAAEILSEAGYRRRRDSKDLTVVDPSNNVE
MAB_2132|M.abscessus_ATCC_1997 MTSTNGALRVAVPNKGALSEAASEILSEAGYRRRGDAKDLTVLDPQNDVE
**:*:****:***.*:***:******* *.*****:** * **
Rv2121c|M.tuberculosis_H37Rv FFFLRPKDIAIYVGSGELDFGITGRDLVCDSGAQVRERLALGFGSSSFRY
Mb2145c|M.bovis_AF2122/97 FFFLRPKDIAIYVGSGELDFGITGRDLVCDSGAQVRERLALGFGSSSFRY
MMAR_3103|M.marinum_M FFFLRPKDIAIYVGSGQLDFGITGRDLVHDSDAQVRERLALGFGSSSFRY
MUL_2352|M.ulcerans_Agy99 FFFLRPKDIAIYVGSGQLDFGITGRDLVHDSDAQVRERLALGFGSSSFRY
MLBr_01310|M.leprae_Br4923 FFFLRPKDIAIYVGSGDLDFGITGRDLVHDSDASVCERLALGFGSSSFRY
MAV_2393|M.avium_104 FFFLRPKDIAIYVGSGELDFGITGRDLVGDSDAPVRERLALGFGSSSFRY
MSMEG_4180|M.smegmatis_MC2_155 FFFLRPKDIAIYVGSGQLDLGITGRDLAADSDAPVRERLSLGFGNSTFRY
TH_0037|M.thermoresistible__bu FFFLRPKDIAIYVGSGDLDLGITGRDLTAESGAPVRERLALGFGSSTFRY
Mflv_3057|M.gilvum_PYR-GCK FFFLRPKDIAIYVGSGELDLGITGRDLAADADAPVRERLALGFGSSTFRY
Mvan_3470|M.vanbaalenii_PYR-1 FFFLRPKDIAIYVGSGELDLGITGRDLAQESDAPVAERLALGFGSSTFRY
MAB_2132|M.abscessus_ATCC_1997 FFFLRPKDIAIYVGSGELDLGITGRDLMMDSDAPVTERLALGFGGSTFRY
****************:**:******* ::.* * ***:****.*:***
Rv2121c|M.tuberculosis_H37Rv AAPAGRNWTTADLAGMRIATAYPNLVRKDLATKGIEATVIRLDGAVEISV
Mb2145c|M.bovis_AF2122/97 AAPAGRNWTTADLAGMRIATAYPNLVRKDLATKGIEATVIRLDGAVEISV
MMAR_3103|M.marinum_M AGPAQRDWTMADLAGKRIATAYPNLVRKDLAAKGIEATVIRLDGAVEISV
MUL_2352|M.ulcerans_Agy99 AGPAQRDWTMADLAGKRIATAYPNLVRKDLTAKGIEATVIRLDGAVEISV
MLBr_01310|M.leprae_Br4923 AGPAGRDWTTSDLAGKRIATAYSNLVRKDLVAKGIEATVIRLDGAVEISV
MAV_2393|M.avium_104 AGPAGRDWKIADLAGKRIATAYPNLVRKDLAERGIEATVIRLDGAVEISV
MSMEG_4180|M.smegmatis_MC2_155 AAPAGREWTTADLAGKRIATSFPNLVRKDLAAHGIDATVIRLDGAVEISI
TH_0037|M.thermoresistible__bu AAPAGRKWTVADLAGKRIATSFPNLVRKDLAARGIDATVIRLDGAVEISV
Mflv_3057|M.gilvum_PYR-GCK AAPAGQDWQIADLAGRRIATAYPNLVRKDLADKGIDATVIRLDGAVEISI
Mvan_3470|M.vanbaalenii_PYR-1 AAPAGTDWTVADLAGRRIATAYPNLVRKDLAHRGIEATVIRLDGAVEISV
MAB_2132|M.abscessus_ATCC_1997 AAPAGRDWTIYDIAGKRIATAYPNLVRKDLAAKGIEAEVIRLDGAVEISI
*.** .* *:** ****::.*******. :**:* ***********:
Rv2121c|M.tuberculosis_H37Rv QLGVADAIADVVGSGRTLSQHDLVAFGEPLCDSEAVLIERAGT---DGQD
Mb2145c|M.bovis_AF2122/97 QLGVADAIADVVGSGRTLSQHDLVAFGEPLCDSEAVLIERAGT---DGQD
MMAR_3103|M.marinum_M QLGVADAIADVVGSGRTLRLHNLVAFGEPLCDSEAVLIEGNGR---DGAA
MUL_2352|M.ulcerans_Agy99 QLGVANAIADVVGSGRTLRLHNLVAFGEPLCDSEAVLIEGNGR---DGAA
MLBr_01310|M.leprae_Br4923 QLGVADVIADVVGSGRTLSLHDLVAFGEPLCDSEAVLIERGDRGSLDHHE
MAV_2393|M.avium_104 QLGVADAIADVVGSGRTLSLHNLVAFGEPLCDSEAVLIESDRG---GQDD
MSMEG_4180|M.smegmatis_MC2_155 QLGVADVIADVVGSGRTLGLHNLVAFGDPLCESEAVLIERDGADG---DE
TH_0037|M.thermoresistible__bu QLGVADAIADVVGSGRTLGLHGLVAFGESLCDSEAVLIERIDAD----PS
Mflv_3057|M.gilvum_PYR-GCK QLGVADVIADIVGSGRTLGLHNLVAFGESLCDSEAILIERADS----DPD
Mvan_3470|M.vanbaalenii_PYR-1 QLGLADVIADIVGTGRTLGLHGLVAFGEALCDSEAVLIERVDA----DPA
MAB_2132|M.abscessus_ATCC_1997 QLGVADVIADIVGTGRTLRQHGLVAFGESLCDSEAVLIERENA----DPA
***:*:.***:**:**** *.*****:.**:***:***
Rv2121c|M.tuberculosis_H37Rv QTEARDQLVARVQGVVFGQQYLMLDYDCPRSALKKATAITPGLESPTIAP
Mb2145c|M.bovis_AF2122/97 QTEARDQLVARVQGVVFGQQYLMLDYDCPRSALKKATAITPGLESPTIAP
MMAR_3103|M.marinum_M QVEARDQLVARVQGVVFGQQYLMLDYDCPRAVLDKATLITPGLESPTIAP
MUL_2352|M.ulcerans_Agy99 QVEARDQLVARVQGVVFGQQYLMLDYDCPRAVLDKATLITPGLESPTIAP
MLBr_01310|M.leprae_Br4923 TVAARDQLVARVQGVVFGQQYLMLDYDCPRSVLDKATLITSGLESPTIAP
MAV_2393|M.avium_104 TQAARDQLVARIQGVVFGQQYLMLDYDCPRAVLDKATAITPGLESPTIAP
MSMEG_4180|M.smegmatis_MC2_155 NAAARDQLTARVQGVVFGQQYLMLDYDCPRAVLDRATAVTPGLESPTIAP
TH_0037|M.thermoresistible__bu NAAARDKLVARVQGVVFGQQYLMLDYDCPRDVLDDAMAITPGLQSPTVAP
Mflv_3057|M.gilvum_PYR-GCK --PARDQLAARVQGVVFGQQYLMLDYDCPRTVLDKATEVTPGLESPTIAP
Mvan_3470|M.vanbaalenii_PYR-1 TAAARDQLAARVQGVVFGQQYLMLDYDCPRSVLERATEVTPGLESPTIAP
MAB_2132|M.abscessus_ATCC_1997 TESARTQLTTRIQGVVFGQQYLMLDYDCPRAVLDEALKVTPGLESPTLAP
** :*.:*:****************** .*. * :*.**:***:**
Rv2121c|M.tuberculosis_H37Rv LADPDWVAIRALVPRRDVNGIMDELAAIGAKAILASDIRFCRF
Mb2145c|M.bovis_AF2122/97 LADPDWVAIRALVPRRDVNGIMDELAAIGAKAILASDIRFCRF
MMAR_3103|M.marinum_M LADPEWVAVRALVPRRDVNGTMDELAAIGAKAILASDIRFCRF
MUL_2352|M.ulcerans_Agy99 LADPEWVAVRALVPRRDVNGTMDELAAIGAKAILASDIRFCRF
MLBr_01310|M.leprae_Br4923 LAEPGWVAIRALVPRRDINGIMDELAAIGAKAILASDIRFCRF
MAV_2393|M.avium_104 LADADWVAIRALVPRRGVNEIMDELAAIGAKAILASDIRFCRF
MSMEG_4180|M.smegmatis_MC2_155 LADPDWVAVRALVPRRDVNAIMDEIAAIGAKAILASDIRFCRF
TH_0037|M.thermoresistible__bu LADPAWVAVRAMVPRRDVNAIMDELGAIGAKAILASEIRFCRF
Mflv_3057|M.gilvum_PYR-GCK LADPAWVAVRALVPRRDVNAIMDELAAIGAKAILASDIRFCRF
Mvan_3470|M.vanbaalenii_PYR-1 LADPDWVAVRALVPRRDVNAIMDELAAIGAKAILASDIRFCRF
MAB_2132|M.abscessus_ATCC_1997 LADEAWVAVRALAPRKGVNTTMDALAAIGAKAILASEVRFFRA
**: ***:**:.**:.:* ** :.**********::** *