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M. ulcerans Agy99 MUL_2352 (hisG)

annotation: ATP phosphoribosyltransferase
coordinates: 2639255 - 2640115
length: 286

SMLRVAVPNKGALSEPATEILAEAGYRRRTDPKDLTVIDPANNVEFFFLRPKDIAIYVGSGQLDFGITGR
DLVHDSDAQVRERLALGFGSSSFRYAGPAQRDWTMADLAGKRIATAYPNLVRKDLTAKGIEATVIRLDGA
VEISVQLGVANAIADVVGSGRTLRLHNLVAFGEPLCDSEAVLIEGNGRDGAAQVEARDQLVARVQGVVFG
QQYLMLDYDCPRAVLDKATLITPGLESPTIAPLADPEWVAVRALVPRRDVNGTMDELAAIGAKAILASDI
RFCRF*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. ulcerans Agy99MUL_2352hisG-100% (286)ATP phosphoribosyltransferase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2145chisG1e-14189.79% (284) ATP phosphoribosyltransferase
M. gilvum PYR-GCKMflv_3057hisG1e-13283.80% (284) ATP phosphoribosyltransferase
M. tuberculosis H37RvRv2121chisG1e-14189.79% (284) ATP phosphoribosyltransferase
M. leprae Br4923MLBr_01310hisG1e-14188.58% (289) ATP phosphoribosyltransferase
M. abscessus ATCC 19977MAB_2132hisG1e-12379.08% (282) ATP phosphoribosyltransferase
M. marinum MMMAR_3103hisG1e-16099.30% (286) ATP phosphoribosyltransferase HisG
M. avium 104MAV_2393hisG1e-13888.03% (284) ATP phosphoribosyltransferase
M. smegmatis MC2 155MSMEG_4180hisG1e-13684.86% (284) ATP phosphoribosyltransferase
M. thermoresistible (build 8)TH_0037hisG1e-12881.34% (284) Probable ATP phosphoribosyltransferase HisG
M. vanbaalenii PYR-1Mvan_3470hisG1e-12982.69% (283) ATP phosphoribosyltransferase

CLUSTAL 2.0.9 multiple sequence alignment


MUL_2352|M.ulcerans_Agy99           ----MSMLRVAVPNKGALSEPATEILAEAGYRRRTDPKDLTVIDPANNVE
MMAR_3103|M.marinum_M               ----MSMLRVAVPNKGALSEPATEILAEAGYRRRTDPKDLTVIDPANNVE
MLBr_01310|M.leprae_Br4923          ----MSMLRVAVPNKGALSEPATEILAEAGYRRRTDPKDLTVVDPVNRVE
Mb2145c|M.bovis_AF2122/97           ------MLRVAVPNKGALSEPATEILAEAGYRRRTDSKDLTVIDPVNNVE
Rv2121c|M.tuberculosis_H37Rv        ------MLRVAVPNKGALSEPATEILAEAGYRRRTDSKDLTVIDPVNNVE
MAV_2393|M.avium_104                ------MLRVAVPNKGTLSEPATEILAEAGYRRRTDSKDLTVIDPVNQVE
MSMEG_4180|M.smegmatis_MC2_155      --MTDQMLRVAVPNKGALSESAAEILAEAGYRRRRDPKDLTVVDPGNNVE
TH_0037|M.thermoresistible__bu      -----VMLRIAMPNKGTLSEPAAEILAEAGYRRRSDTKDLTVVDPVNEVE
Mflv_3057|M.gilvum_PYR-GCK          ------MLRVAVPNKGALSESASEILSEAGYRRRSDPKDLTVVDPANNVE
Mvan_3470|M.vanbaalenii_PYR-1       -MSAPKTLRVAVPNKGALSESAAEILSEAGYRRRRDSKDLTVVDPSNNVE
MAB_2132|M.abscessus_ATCC_1997      MTSTNGALRVAVPNKGALSEAASEILSEAGYRRRGDAKDLTVLDPQNDVE
                                           **:*:****:***.*:***:******* *.*****:** * **

MUL_2352|M.ulcerans_Agy99           FFFLRPKDIAIYVGSGQLDFGITGRDLVHDSDAQVRERLALGFGSSSFRY
MMAR_3103|M.marinum_M               FFFLRPKDIAIYVGSGQLDFGITGRDLVHDSDAQVRERLALGFGSSSFRY
MLBr_01310|M.leprae_Br4923          FFFLRPKDIAIYVGSGDLDFGITGRDLVHDSDASVCERLALGFGSSSFRY
Mb2145c|M.bovis_AF2122/97           FFFLRPKDIAIYVGSGELDFGITGRDLVCDSGAQVRERLALGFGSSSFRY
Rv2121c|M.tuberculosis_H37Rv        FFFLRPKDIAIYVGSGELDFGITGRDLVCDSGAQVRERLALGFGSSSFRY
MAV_2393|M.avium_104                FFFLRPKDIAIYVGSGELDFGITGRDLVGDSDAPVRERLALGFGSSSFRY
MSMEG_4180|M.smegmatis_MC2_155      FFFLRPKDIAIYVGSGQLDLGITGRDLAADSDAPVRERLSLGFGNSTFRY
TH_0037|M.thermoresistible__bu      FFFLRPKDIAIYVGSGDLDLGITGRDLTAESGAPVRERLALGFGSSTFRY
Mflv_3057|M.gilvum_PYR-GCK          FFFLRPKDIAIYVGSGELDLGITGRDLAADADAPVRERLALGFGSSTFRY
Mvan_3470|M.vanbaalenii_PYR-1       FFFLRPKDIAIYVGSGELDLGITGRDLAQESDAPVAERLALGFGSSTFRY
MAB_2132|M.abscessus_ATCC_1997      FFFLRPKDIAIYVGSGELDLGITGRDLMMDSDAPVTERLALGFGGSTFRY
                                    ****************:**:*******  ::.* * ***:****.*:***

MUL_2352|M.ulcerans_Agy99           AGPAQRDWTMADLAGKRIATAYPNLVRKDLTAKGIEATVIRLDGAVEISV
MMAR_3103|M.marinum_M               AGPAQRDWTMADLAGKRIATAYPNLVRKDLAAKGIEATVIRLDGAVEISV
MLBr_01310|M.leprae_Br4923          AGPAGRDWTTSDLAGKRIATAYSNLVRKDLVAKGIEATVIRLDGAVEISV
Mb2145c|M.bovis_AF2122/97           AAPAGRNWTTADLAGMRIATAYPNLVRKDLATKGIEATVIRLDGAVEISV
Rv2121c|M.tuberculosis_H37Rv        AAPAGRNWTTADLAGMRIATAYPNLVRKDLATKGIEATVIRLDGAVEISV
MAV_2393|M.avium_104                AGPAGRDWKIADLAGKRIATAYPNLVRKDLAERGIEATVIRLDGAVEISV
MSMEG_4180|M.smegmatis_MC2_155      AAPAGREWTTADLAGKRIATSFPNLVRKDLAAHGIDATVIRLDGAVEISI
TH_0037|M.thermoresistible__bu      AAPAGRKWTVADLAGKRIATSFPNLVRKDLAARGIDATVIRLDGAVEISV
Mflv_3057|M.gilvum_PYR-GCK          AAPAGQDWQIADLAGRRIATAYPNLVRKDLADKGIDATVIRLDGAVEISI
Mvan_3470|M.vanbaalenii_PYR-1       AAPAGTDWTVADLAGRRIATAYPNLVRKDLAHRGIEATVIRLDGAVEISV
MAB_2132|M.abscessus_ATCC_1997      AAPAGRDWTIYDIAGKRIATAYPNLVRKDLAAKGIEAEVIRLDGAVEISI
                                    *.**  .*   *:** ****::.*******. :**:* ***********:

MUL_2352|M.ulcerans_Agy99           QLGVANAIADVVGSGRTLRLHNLVAFGEPLCDSEAVLIEGNGR---DGAA
MMAR_3103|M.marinum_M               QLGVADAIADVVGSGRTLRLHNLVAFGEPLCDSEAVLIEGNGR---DGAA
MLBr_01310|M.leprae_Br4923          QLGVADVIADVVGSGRTLSLHDLVAFGEPLCDSEAVLIERGDRGSLDHHE
Mb2145c|M.bovis_AF2122/97           QLGVADAIADVVGSGRTLSQHDLVAFGEPLCDSEAVLIERAGT---DGQD
Rv2121c|M.tuberculosis_H37Rv        QLGVADAIADVVGSGRTLSQHDLVAFGEPLCDSEAVLIERAGT---DGQD
MAV_2393|M.avium_104                QLGVADAIADVVGSGRTLSLHNLVAFGEPLCDSEAVLIESDRG---GQDD
MSMEG_4180|M.smegmatis_MC2_155      QLGVADVIADVVGSGRTLGLHNLVAFGDPLCESEAVLIERDGADG---DE
TH_0037|M.thermoresistible__bu      QLGVADAIADVVGSGRTLGLHGLVAFGESLCDSEAVLIERIDAD----PS
Mflv_3057|M.gilvum_PYR-GCK          QLGVADVIADIVGSGRTLGLHNLVAFGESLCDSEAILIERADS----DPD
Mvan_3470|M.vanbaalenii_PYR-1       QLGLADVIADIVGTGRTLGLHGLVAFGEALCDSEAVLIERVDA----DPA
MAB_2132|M.abscessus_ATCC_1997      QLGVADVIADIVGTGRTLRQHGLVAFGESLCDSEAVLIERENA----DPA
                                    ***:*:.***:**:****  *.*****:.**:***:***           

MUL_2352|M.ulcerans_Agy99           QVEARDQLVARVQGVVFGQQYLMLDYDCPRAVLDKATLITPGLESPTIAP
MMAR_3103|M.marinum_M               QVEARDQLVARVQGVVFGQQYLMLDYDCPRAVLDKATLITPGLESPTIAP
MLBr_01310|M.leprae_Br4923          TVAARDQLVARVQGVVFGQQYLMLDYDCPRSVLDKATLITSGLESPTIAP
Mb2145c|M.bovis_AF2122/97           QTEARDQLVARVQGVVFGQQYLMLDYDCPRSALKKATAITPGLESPTIAP
Rv2121c|M.tuberculosis_H37Rv        QTEARDQLVARVQGVVFGQQYLMLDYDCPRSALKKATAITPGLESPTIAP
MAV_2393|M.avium_104                TQAARDQLVARIQGVVFGQQYLMLDYDCPRAVLDKATAITPGLESPTIAP
MSMEG_4180|M.smegmatis_MC2_155      NAAARDQLTARVQGVVFGQQYLMLDYDCPRAVLDRATAVTPGLESPTIAP
TH_0037|M.thermoresistible__bu      NAAARDKLVARVQGVVFGQQYLMLDYDCPRDVLDDAMAITPGLQSPTVAP
Mflv_3057|M.gilvum_PYR-GCK          --PARDQLAARVQGVVFGQQYLMLDYDCPRTVLDKATEVTPGLESPTIAP
Mvan_3470|M.vanbaalenii_PYR-1       TAAARDQLAARVQGVVFGQQYLMLDYDCPRSVLERATEVTPGLESPTIAP
MAB_2132|M.abscessus_ATCC_1997      TESARTQLTTRIQGVVFGQQYLMLDYDCPRAVLDEALKVTPGLESPTLAP
                                       ** :*.:*:****************** .*. *  :*.**:***:**

MUL_2352|M.ulcerans_Agy99           LADPEWVAVRALVPRRDVNGTMDELAAIGAKAILASDIRFCRF
MMAR_3103|M.marinum_M               LADPEWVAVRALVPRRDVNGTMDELAAIGAKAILASDIRFCRF
MLBr_01310|M.leprae_Br4923          LAEPGWVAIRALVPRRDINGIMDELAAIGAKAILASDIRFCRF
Mb2145c|M.bovis_AF2122/97           LADPDWVAIRALVPRRDVNGIMDELAAIGAKAILASDIRFCRF
Rv2121c|M.tuberculosis_H37Rv        LADPDWVAIRALVPRRDVNGIMDELAAIGAKAILASDIRFCRF
MAV_2393|M.avium_104                LADADWVAIRALVPRRGVNEIMDELAAIGAKAILASDIRFCRF
MSMEG_4180|M.smegmatis_MC2_155      LADPDWVAVRALVPRRDVNAIMDEIAAIGAKAILASDIRFCRF
TH_0037|M.thermoresistible__bu      LADPAWVAVRAMVPRRDVNAIMDELGAIGAKAILASEIRFCRF
Mflv_3057|M.gilvum_PYR-GCK          LADPAWVAVRALVPRRDVNAIMDELAAIGAKAILASDIRFCRF
Mvan_3470|M.vanbaalenii_PYR-1       LADPDWVAVRALVPRRDVNAIMDELAAIGAKAILASDIRFCRF
MAB_2132|M.abscessus_ATCC_1997      LADEAWVAVRALAPRKGVNTTMDALAAIGAKAILASEVRFFRA
                                    **:  ***:**:.**:.:*  ** :.**********::** *