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M. smegmatis MC2 155 MSMEG_4180 (hisG)

annotation: ATP phosphoribosyltransferase
coordinates: 4257530 - 4258396
length: 288

TDQMLRVAVPNKGALSESAAEILAEAGYRRRRDPKDLTVVDPGNNVEFFFLRPKDIAIYVGSGQLDLGIT
GRDLAADSDAPVRERLSLGFGNSTFRYAAPAGREWTTADLAGKRIATSFPNLVRKDLAAHGIDATVIRLD
GAVEISIQLGVADVIADVVGSGRTLGLHNLVAFGDPLCESEAVLIERDGADGDENAAARDQLTARVQGVV
FGQQYLMLDYDCPRAVLDRATAVTPGLESPTIAPLADPDWVAVRALVPRRDVNAIMDEIAAIGAKAILAS
DIRFCRF*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_4180hisG-100% (288)ATP phosphoribosyltransferase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2145chisG1e-13684.15% (284) ATP phosphoribosyltransferase
M. gilvum PYR-GCKMflv_3057hisG1e-13886.97% (284) ATP phosphoribosyltransferase
M. tuberculosis H37RvRv2121chisG1e-13684.15% (284) ATP phosphoribosyltransferase
M. leprae Br4923MLBr_01310hisG1e-13282.58% (287) ATP phosphoribosyltransferase
M. abscessus ATCC 19977MAB_2132hisG1e-12478.67% (286) ATP phosphoribosyltransferase
M. marinum MMMAR_3103hisG1e-13785.56% (284) ATP phosphoribosyltransferase HisG
M. avium 104MAV_2393hisG1e-13583.80% (284) ATP phosphoribosyltransferase
M. thermoresistible (build 8)TH_0037hisG1e-13585.56% (284) Probable ATP phosphoribosyltransferase HisG
M. ulcerans Agy99MUL_2352hisG1e-13784.86% (284) ATP phosphoribosyltransferase
M. vanbaalenii PYR-1Mvan_3470hisG1e-13886.93% (283) ATP phosphoribosyltransferase

CLUSTAL 2.0.9 multiple sequence alignment


MSMEG_4180|M.smegmatis_MC2_155      --MTDQMLRVAVPNKGALSESAAEILAEAGYRRRRDPKDLTVVDPGNNVE
TH_0037|M.thermoresistible__bu      -----VMLRIAMPNKGTLSEPAAEILAEAGYRRRSDTKDLTVVDPVNEVE
Mb2145c|M.bovis_AF2122/97           ------MLRVAVPNKGALSEPATEILAEAGYRRRTDSKDLTVIDPVNNVE
Rv2121c|M.tuberculosis_H37Rv        ------MLRVAVPNKGALSEPATEILAEAGYRRRTDSKDLTVIDPVNNVE
MMAR_3103|M.marinum_M               ----MSMLRVAVPNKGALSEPATEILAEAGYRRRTDPKDLTVIDPANNVE
MUL_2352|M.ulcerans_Agy99           ----MSMLRVAVPNKGALSEPATEILAEAGYRRRTDPKDLTVIDPANNVE
MLBr_01310|M.leprae_Br4923          ----MSMLRVAVPNKGALSEPATEILAEAGYRRRTDPKDLTVVDPVNRVE
MAV_2393|M.avium_104                ------MLRVAVPNKGTLSEPATEILAEAGYRRRTDSKDLTVIDPVNQVE
Mflv_3057|M.gilvum_PYR-GCK          ------MLRVAVPNKGALSESASEILSEAGYRRRSDPKDLTVVDPANNVE
Mvan_3470|M.vanbaalenii_PYR-1       -MSAPKTLRVAVPNKGALSESAAEILSEAGYRRRRDSKDLTVVDPSNNVE
MAB_2132|M.abscessus_ATCC_1997      MTSTNGALRVAVPNKGALSEAASEILSEAGYRRRGDAKDLTVLDPQNDVE
                                           **:*:****:***.*:***:******* *.*****:** * **

MSMEG_4180|M.smegmatis_MC2_155      FFFLRPKDIAIYVGSGQLDLGITGRDLAADSDAPVRERLSLGFGNSTFRY
TH_0037|M.thermoresistible__bu      FFFLRPKDIAIYVGSGDLDLGITGRDLTAESGAPVRERLALGFGSSTFRY
Mb2145c|M.bovis_AF2122/97           FFFLRPKDIAIYVGSGELDFGITGRDLVCDSGAQVRERLALGFGSSSFRY
Rv2121c|M.tuberculosis_H37Rv        FFFLRPKDIAIYVGSGELDFGITGRDLVCDSGAQVRERLALGFGSSSFRY
MMAR_3103|M.marinum_M               FFFLRPKDIAIYVGSGQLDFGITGRDLVHDSDAQVRERLALGFGSSSFRY
MUL_2352|M.ulcerans_Agy99           FFFLRPKDIAIYVGSGQLDFGITGRDLVHDSDAQVRERLALGFGSSSFRY
MLBr_01310|M.leprae_Br4923          FFFLRPKDIAIYVGSGDLDFGITGRDLVHDSDASVCERLALGFGSSSFRY
MAV_2393|M.avium_104                FFFLRPKDIAIYVGSGELDFGITGRDLVGDSDAPVRERLALGFGSSSFRY
Mflv_3057|M.gilvum_PYR-GCK          FFFLRPKDIAIYVGSGELDLGITGRDLAADADAPVRERLALGFGSSTFRY
Mvan_3470|M.vanbaalenii_PYR-1       FFFLRPKDIAIYVGSGELDLGITGRDLAQESDAPVAERLALGFGSSTFRY
MAB_2132|M.abscessus_ATCC_1997      FFFLRPKDIAIYVGSGELDLGITGRDLMMDSDAPVTERLALGFGGSTFRY
                                    ****************:**:*******  ::.* * ***:****.*:***

MSMEG_4180|M.smegmatis_MC2_155      AAPAGREWTTADLAGKRIATSFPNLVRKDLAAHGIDATVIRLDGAVEISI
TH_0037|M.thermoresistible__bu      AAPAGRKWTVADLAGKRIATSFPNLVRKDLAARGIDATVIRLDGAVEISV
Mb2145c|M.bovis_AF2122/97           AAPAGRNWTTADLAGMRIATAYPNLVRKDLATKGIEATVIRLDGAVEISV
Rv2121c|M.tuberculosis_H37Rv        AAPAGRNWTTADLAGMRIATAYPNLVRKDLATKGIEATVIRLDGAVEISV
MMAR_3103|M.marinum_M               AGPAQRDWTMADLAGKRIATAYPNLVRKDLAAKGIEATVIRLDGAVEISV
MUL_2352|M.ulcerans_Agy99           AGPAQRDWTMADLAGKRIATAYPNLVRKDLTAKGIEATVIRLDGAVEISV
MLBr_01310|M.leprae_Br4923          AGPAGRDWTTSDLAGKRIATAYSNLVRKDLVAKGIEATVIRLDGAVEISV
MAV_2393|M.avium_104                AGPAGRDWKIADLAGKRIATAYPNLVRKDLAERGIEATVIRLDGAVEISV
Mflv_3057|M.gilvum_PYR-GCK          AAPAGQDWQIADLAGRRIATAYPNLVRKDLADKGIDATVIRLDGAVEISI
Mvan_3470|M.vanbaalenii_PYR-1       AAPAGTDWTVADLAGRRIATAYPNLVRKDLAHRGIEATVIRLDGAVEISV
MAB_2132|M.abscessus_ATCC_1997      AAPAGRDWTIYDIAGKRIATAYPNLVRKDLAAKGIEAEVIRLDGAVEISI
                                    *.**  .*   *:** ****::.*******. :**:* ***********:

MSMEG_4180|M.smegmatis_MC2_155      QLGVADVIADVVGSGRTLGLHNLVAFGDPLCESEAVLIERDGADG---DE
TH_0037|M.thermoresistible__bu      QLGVADAIADVVGSGRTLGLHGLVAFGESLCDSEAVLIERIDAD----PS
Mb2145c|M.bovis_AF2122/97           QLGVADAIADVVGSGRTLSQHDLVAFGEPLCDSEAVLIERAGT---DGQD
Rv2121c|M.tuberculosis_H37Rv        QLGVADAIADVVGSGRTLSQHDLVAFGEPLCDSEAVLIERAGT---DGQD
MMAR_3103|M.marinum_M               QLGVADAIADVVGSGRTLRLHNLVAFGEPLCDSEAVLIEGNGR---DGAA
MUL_2352|M.ulcerans_Agy99           QLGVANAIADVVGSGRTLRLHNLVAFGEPLCDSEAVLIEGNGR---DGAA
MLBr_01310|M.leprae_Br4923          QLGVADVIADVVGSGRTLSLHDLVAFGEPLCDSEAVLIERGDRGSLDHHE
MAV_2393|M.avium_104                QLGVADAIADVVGSGRTLSLHNLVAFGEPLCDSEAVLIESDRG---GQDD
Mflv_3057|M.gilvum_PYR-GCK          QLGVADVIADIVGSGRTLGLHNLVAFGESLCDSEAILIERADS----DPD
Mvan_3470|M.vanbaalenii_PYR-1       QLGLADVIADIVGTGRTLGLHGLVAFGEALCDSEAVLIERVDA----DPA
MAB_2132|M.abscessus_ATCC_1997      QLGVADVIADIVGTGRTLRQHGLVAFGESLCDSEAVLIERENA----DPA
                                    ***:*:.***:**:****  *.*****:.**:***:***           

MSMEG_4180|M.smegmatis_MC2_155      NAAARDQLTARVQGVVFGQQYLMLDYDCPRAVLDRATAVTPGLESPTIAP
TH_0037|M.thermoresistible__bu      NAAARDKLVARVQGVVFGQQYLMLDYDCPRDVLDDAMAITPGLQSPTVAP
Mb2145c|M.bovis_AF2122/97           QTEARDQLVARVQGVVFGQQYLMLDYDCPRSALKKATAITPGLESPTIAP
Rv2121c|M.tuberculosis_H37Rv        QTEARDQLVARVQGVVFGQQYLMLDYDCPRSALKKATAITPGLESPTIAP
MMAR_3103|M.marinum_M               QVEARDQLVARVQGVVFGQQYLMLDYDCPRAVLDKATLITPGLESPTIAP
MUL_2352|M.ulcerans_Agy99           QVEARDQLVARVQGVVFGQQYLMLDYDCPRAVLDKATLITPGLESPTIAP
MLBr_01310|M.leprae_Br4923          TVAARDQLVARVQGVVFGQQYLMLDYDCPRSVLDKATLITSGLESPTIAP
MAV_2393|M.avium_104                TQAARDQLVARIQGVVFGQQYLMLDYDCPRAVLDKATAITPGLESPTIAP
Mflv_3057|M.gilvum_PYR-GCK          --PARDQLAARVQGVVFGQQYLMLDYDCPRTVLDKATEVTPGLESPTIAP
Mvan_3470|M.vanbaalenii_PYR-1       TAAARDQLAARVQGVVFGQQYLMLDYDCPRSVLERATEVTPGLESPTIAP
MAB_2132|M.abscessus_ATCC_1997      TESARTQLTTRIQGVVFGQQYLMLDYDCPRAVLDEALKVTPGLESPTLAP
                                       ** :*.:*:****************** .*. *  :*.**:***:**

MSMEG_4180|M.smegmatis_MC2_155      LADPDWVAVRALVPRRDVNAIMDEIAAIGAKAILASDIRFCRF
TH_0037|M.thermoresistible__bu      LADPAWVAVRAMVPRRDVNAIMDELGAIGAKAILASEIRFCRF
Mb2145c|M.bovis_AF2122/97           LADPDWVAIRALVPRRDVNGIMDELAAIGAKAILASDIRFCRF
Rv2121c|M.tuberculosis_H37Rv        LADPDWVAIRALVPRRDVNGIMDELAAIGAKAILASDIRFCRF
MMAR_3103|M.marinum_M               LADPEWVAVRALVPRRDVNGTMDELAAIGAKAILASDIRFCRF
MUL_2352|M.ulcerans_Agy99           LADPEWVAVRALVPRRDVNGTMDELAAIGAKAILASDIRFCRF
MLBr_01310|M.leprae_Br4923          LAEPGWVAIRALVPRRDINGIMDELAAIGAKAILASDIRFCRF
MAV_2393|M.avium_104                LADADWVAIRALVPRRGVNEIMDELAAIGAKAILASDIRFCRF
Mflv_3057|M.gilvum_PYR-GCK          LADPAWVAVRALVPRRDVNAIMDELAAIGAKAILASDIRFCRF
Mvan_3470|M.vanbaalenii_PYR-1       LADPDWVAVRALVPRRDVNAIMDELAAIGAKAILASDIRFCRF
MAB_2132|M.abscessus_ATCC_1997      LADEAWVAVRALAPRKGVNTTMDALAAIGAKAILASEVRFFRA
                                    **:  ***:**:.**:.:*  ** :.**********::** *