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DEIESLIGLRPTPLTWPVVIAGDFLGVWDPPPSLPGAANHEISAPTARISCMLIERRDAAARLRRALHRA PVVLLTGPRQAGKTTLSRLVGKSAPECTFDAENPVDATRLADPMLALSGLSGLITIDEAQRIPDLFPVLR VLVDRPVMPARFLILGSASPDLVGLASESLAGRVELVELSGLTVRDVGSSAADRLWLRGGLPPSFTARSN EDSAAWRDGYITTFLERDLAQLGVRIPAATMRRAWTMLAHYHGQLFSGAELARSLDVAQTTARRYLDALT DALVVRQLTPWFANIGKRQRRSPKIYIRDTGLLHRLLGIDDRLALERNPKLGASWEGFVLEQLAALLAPN PLYYWRTQQDAELDLYVELSGRPYGFEIKRTSTPSISRSMRSALVDLQLARLAIVYPGEHRFPLSDTVVA VPADQILTTGSVDELLALLK*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv2008c | - | - | 100% (441) | hypothetical protein Rv2008c |
| M. tuberculosis H37Rv | Rv0597c | - | 3e-30 | 31.52% (368) | hypothetical protein Rv0597c |
| M. tuberculosis H37Rv | Rv3179 | - | 9e-23 | 26.78% (422) | hypothetical protein Rv3179 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2031c | - | 0.0 | 100.00% (441) | hypothetical protein Mb2031c |
| M. gilvum PYR-GCK | Mflv_1328 | - | 1e-07 | 80.00% (30) | peptide chain release factor 3 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | - | - | - | - | - |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_1316 | prfC | 5e-07 | 73.33% (30) | peptide chain release factor 3 |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_5464 | - | 3e-08 | 83.33% (30) | peptide chain release factor 3 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1328|M.gilvum_PYR-GCK MTSANKIDGIMTNSTADASTTAAKRSDRVSNEAQRRRTFAVISHPDAGKS
Mvan_5464|M.vanbaalenii_PYR-1 ----------MT-----TSTAAGPRADLVSAEARRRRTFAVISHPDAGKS
MSMEG_1316|M.smegmatis_MC2_155 ----------MTDTPALAPSANTSLSRRIAAEATRRRTFAVISHPDAGKS
Rv2008c|M.tuberculosis_H37Rv ---------------------MDEIESLIGLRPTPLTWPVVIAG------
Mb2031c|M.bovis_AF2122/97 ---------------------MDEIESLIGLRPTPLTWPVVIAG------
:. .. .**:
Mflv_1328|M.gilvum_PYR-GCK TLTEALVLHAKAITEAGAIHGKQGRRATVSDWMEMEKARGISITSTALQF
Mvan_5464|M.vanbaalenii_PYR-1 TLTEALVLHAKAITEAGAIHGKAGRRATVSDWMEMEKARGISITSTALQF
MSMEG_1316|M.smegmatis_MC2_155 TLTEALALHARVITEAGAIHGKAGRRSTVSDWMEMEKARGISITSTVLQF
Rv2008c|M.tuberculosis_H37Rv ---DFLGVWDPPPSLPGAANHEISAPTARISCMLIERRDAAARLRRALH-
Mb2031c|M.bovis_AF2122/97 ---DFLGVWDPPPSLPGAANHEISAPTARISCMLIERRDAAARLRRALH-
: * : : .** : : . :: . * :*: . : .*:
Mflv_1328|M.gilvum_PYR-GCK PYTTQAGDTCVINLLDTPGHADFSEDTYRVLTAVDSAVMLIDAAKGLEPQ
Mvan_5464|M.vanbaalenii_PYR-1 PYITQAGNTCVINLLDTPGHADFSEDTYRVLTAVDSAVMLIDAAKGLEPQ
MSMEG_1316|M.smegmatis_MC2_155 PYR-----DSVINLLDTPGHADFSEDTYRVLTAVDCAVMLIDAAKGLEPQ
Rv2008c|M.tuberculosis_H37Rv --------RAPVVLLTGP--RQAGKTTLSRLVGKSAPECTFDAENPVDAT
Mb2031c|M.bovis_AF2122/97 --------RAPVVLLTGP--RQAGKTTLSRLVGKSAPECTFDAENPVDAT
. : ** * : .: * *.. ... :** : ::.
Mflv_1328|M.gilvum_PYR-GCK TLKLFQVCAHRRIPIITVINKWDRPGRHALELMDEINERIGLRPTPLTWP
Mvan_5464|M.vanbaalenii_PYR-1 TLKLFQVCRHRRIPIITVVNKWDRPGRHALELMDEIQSQIGLRPTPLTWP
MSMEG_1316|M.smegmatis_MC2_155 TLKLFQVCKHRGIPIITVINKWDRPGRHALELIDEIQTRIGLKPTPLTWP
Rv2008c|M.tuberculosis_H37Rv RLADPMLALS---------------GLSGLITIDEAQRIPDLFP------
Mb2031c|M.bovis_AF2122/97 RLADPMLALS---------------GLSGLITIDEAQRIPDLFP------
* :. * .* :** : .* *
Mflv_1328|M.gilvum_PYR-GCK VGIAGDFKGVLDRRTGKFIRFTRTAGGATAAPEEHIAAEAAHDAAGIDWD
Mvan_5464|M.vanbaalenii_PYR-1 VGIAGDFKGVLDRRTGKFIRFTRTAGGATAAPEEHIDPDKAHDAAGVDWD
MSMEG_1316|M.smegmatis_MC2_155 VGIAGDFKGVLDRRGGQFIRFTRTAGGATAAPEEHIPADAAHAAAGDDWD
Rv2008c|M.tuberculosis_H37Rv -----VLRVLVDR--------------PVMPARFLILGSASPDLVGLASE
Mb2031c|M.bovis_AF2122/97 -----VLRVLVDR--------------PVMPARFLILGSASPDLVGLASE
:: ::** .. ... * . : .* :
Mflv_1328|M.gilvum_PYR-GCK NAVEESELLEADGADFDPDSFLDCTSTPVLFTSAALNFGVNQLLDVLSAL
Mvan_5464|M.vanbaalenii_PYR-1 NAVEESELLSADGADFDPDTFLDCTSTPVLFTSAALNFGVNQLLDVLAQL
MSMEG_1316|M.smegmatis_MC2_155 TAVEESELLSADGGDYDRDAFLAGTASPTLFTSAALNFGVNQLLDVLVEL
Rv2008c|M.tuberculosis_H37Rv SLAGRVELVELSG-----------------LTVRDVGSSAADRLWLRGGL
Mb2031c|M.bovis_AF2122/97 SLAGRVELVELSG-----------------LTVRDVGSSAADRLWLRGGL
. . . **:. .* :* :. .. : * : *
Mflv_1328|M.gilvum_PYR-GCK APSPNGQLDVDGNRREAAAPFSAFVFKVQAGMDSAHRDRIAYARVCSGTF
Mvan_5464|M.vanbaalenii_PYR-1 APSPNGALDVDGNRREAAAPFSAFVFKVQAGMDSAHRDRIAYARVCSGTF
MSMEG_1316|M.smegmatis_MC2_155 APSPNGALDVDGERRDPDAPFSAFVFKVQAGMDSAHRDRIAYARVVSGTF
Rv2008c|M.tuberculosis_H37Rv PPSFTARSNEDSAAWR-DGYITTFLERDLAQLG---------VRIPAATM
Mb2031c|M.bovis_AF2122/97 PPSFTARSNEDSAAWR-DGYITTFLERDLAQLG---------VRIPAATM
.** .. : *. . :::*: : * :. .*: :.*:
Mflv_1328|M.gilvum_PYR-GCK ERGDVLTHATTGKPFVTKYAQSVFGRERSTLDTAWPGDVIGLANANALRP
Mvan_5464|M.vanbaalenii_PYR-1 ERGDVLTHASTGKPFVTKYAQSVFGRERSTLDTAWPGDVIGLANAAALRP
MSMEG_1316|M.smegmatis_MC2_155 ERGDVLTHAATGKPFVTKYAQSVFGQQRSTLDDAWPGDVIGLANAQALRP
Rv2008c|M.tuberculosis_H37Rv RRAWTMLAHYHGQLFSG----AELARSLDVAQTTARRYLDALTDALVVRQ
Mb2031c|M.bovis_AF2122/97 RRAWTMLAHYHGQLFSG----AELARSLDVAQTTARRYLDALTDALVVRQ
.*. .: *: * : :.:. .. : : : .*::* .:*
Mflv_1328|M.gilvum_PYR-GCK GDTLYQDVAVQFPPIPSFSPEHFSVARGTDPSKHKQFRKGIEQLDQEGVV
Mvan_5464|M.vanbaalenii_PYR-1 GDTLYQDIAVQYPPIPSFSPEHFSVARGTDPSKHKQFRKGIEQLDQEGVV
MSMEG_1316|M.smegmatis_MC2_155 GDTLYRDVPVQFPPIPSFSPEHFAVARGTDPSKHKQFRRGIEQLEQEGVV
Rv2008c|M.tuberculosis_H37Rv LTPWFANIGKRQRRSPKIY------IRDTGLLHRLLGIDDRLALERNPKL
Mb2031c|M.bovis_AF2122/97 LTPWFANIGKRQRRSPKIY------IRDTGLLHRLLGIDDRLALERNPKL
. : :: : *.: *.*. :: . *::: :
Mflv_1328|M.gilvum_PYR-GCK QVLRSDRRGDQAPVLAAVGPMQFEVAAHRMAAEFSAPIELESLPYQVARI
Mvan_5464|M.vanbaalenii_PYR-1 QVLRSDRRGEQAPVLAAVGPMQFEVASHRMAAEFSAPIALESLPYTIARI
MSMEG_1316|M.smegmatis_MC2_155 QVLRSDKRGEQAPVFAAVGPMQFEVASHRMATELSAPISLEPLPYQVARI
Rv2008c|M.tuberculosis_H37Rv GASWEGFVLEQLAALLAPNPLYYWRTQQDAELDLYVELSGRPYGFEIKRT
Mb2031c|M.bovis_AF2122/97 GASWEGFVLEQLAALLAPNPLYYWRTQQDAELDLYVELSGRPYGFEIKRT
. .. :* ..: * .*: : : : :: . : .. : : *
Mflv_1328|M.gilvum_PYR-GCK CDPADAEALQKMAAVEVFTRTDGVMLAVFSTKWRLETVQRDNPDIMLREL
Mvan_5464|M.vanbaalenii_PYR-1 CDPADAEALAKMAAVEVFTRTDGVMLAVFSTKWRLETVQRENPAMELREL
MSMEG_1316|M.smegmatis_MC2_155 VDPEDADFMNRQPSAEVMTRSDGVMLVLFSTPWRLEGFQRDNPDIKLRSL
Rv2008c|M.tuberculosis_H37Rv STPSISRSMRSALVDLQLARLAIVYPGEHRFPLSDTVVAVPADQILTTGS
Mb2031c|M.bovis_AF2122/97 STPSISRSMRSALVDLQLARLAIVYPGEHRFPLSDTVVAVPADQILTTGS
* : : ::* * . . :
Mflv_1328|M.gilvum_PYR-GCK IAAGQE---
Mvan_5464|M.vanbaalenii_PYR-1 VAAGQ----
MSMEG_1316|M.smegmatis_MC2_155 VAS------
Rv2008c|M.tuberculosis_H37Rv VDELLALLK
Mb2031c|M.bovis_AF2122/97 VDELLALLK
: