For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MVIVADKAAGRVADPVLRPVGALGDFFAMTLDTSVCMFKPPFAWREYLLQCWFVARVSTLPGVLMTIPWA VISGFLFNVLLTDIGAADFSGTGCAIFTVNQSAPIVTVLVVAGAGATAMCADLGARTIREELDALRVMGI NPIQALAAPRVLAATTVSLALNSVVTATGLIGAFFCSVFLMHVSAGAWVTGLTTLTHTVDVVISMIKATL FGLMAGLIACYKGMSVGGGPAGVGRAVNETVVFAFIVLFVINIVVTAVGIPFMVS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv1964 | yrbE3A | - | 100% (265) | CONSERVED HYPOTHETICAL INTEGRAL MEMBRANE PROTEIN YRBE3A |
| M. tuberculosis H37Rv | Rv3501c | yrbE4A | 2e-79 | 59.09% (242) | integral membrane protein YrbE4a |
| M. tuberculosis H37Rv | Rv0167 | yrbE1A | 2e-73 | 50.19% (261) | integral membrane protein YRBE1A |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3531c | yrbE4A | 2e-79 | 59.09% (242) | integral membrane protein YrbE4a |
| M. gilvum PYR-GCK | Mflv_2099 | - | 3e-92 | 66.94% (245) | hypothetical protein Mflv_2099 |
| M. leprae Br4923 | MLBr_02587 | yrbE1A | 3e-72 | 52.05% (244) | hypothetical protein MLBr_02587 |
| M. abscessus ATCC 19977 | MAB_4155c | - | 8e-77 | 57.32% (246) | hypothetical protein MAB_4155c |
| M. marinum M | MMAR_2880 | yrbE3A | 1e-134 | 88.09% (277) | integral membrane protein YrbE3A |
| M. avium 104 | MAV_2530 | - | 7e-82 | 60.74% (242) | TrnB1 protein |
| M. smegmatis MC2 155 | MSMEG_0344 | - | 4e-95 | 67.20% (250) | hypothetical protein MSMEG_0344 |
| M. thermoresistible (build 8) | TH_0179 | - | 1e-102 | 74.00% (250) | CONSERVED HYPOTHETICAL INTEGRAL MEMBRANE PROTEIN YRBE4A |
| M. ulcerans Agy99 | MUL_2872 | yrbE3A | 1e-132 | 87.36% (277) | integral membrane protein YrbE3A |
| M. vanbaalenii PYR-1 | Mvan_3984 | - | 2e-97 | 69.72% (251) | hypothetical protein Mvan_3984 |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_2880|M.marinum_M ----MVRDTMVALTDRAASPVADPVADAVARPLAGSVTKPVRALGDFFAM
MUL_2872|M.ulcerans_Agy99 ---------MVTLTDRAASPVADPVADPVARPLAGSVTKPVRALGDFFAM
Rv1964|M.tuberculosis_H37Rv ---------MVIVADKAAGRVADPVLRPVG------------ALGDFFAM
TH_0179|M.thermoresistible__bu ---------MVLAPQPVTEPVR--------------------AVGGFFAM
Mvan_3984|M.vanbaalenii_PYR-1 ---------MLIASHPATKPVR--------------------ALGGFFAM
Mflv_2099|M.gilvum_PYR-GCK ----------MVASGVIAKPMR--------------------AFGGFFSM
MSMEG_0344|M.smegmatis_MC2_155 ----------MIALGPAAKPVG--------------------ALGGFFAM
MAV_2530|M.avium_104 ---------MVESPGTPRLAVAGKPLR---------------EVGSYFAL
Mb3531c|M.bovis_AF2122/97 ------------MIQQLAVPAR--------------------AVGGFFEM
MAB_4155c|M.abscessus_ATCC_199 ------------MKQQLAAPAR--------------------AVGGFVSM
MLBr_02587|M.leprae_Br4923 MTTETRSSLVEYAHTKLQTPLV--------------------LVGGFFRM
.*.:. :
MMAR_2880|M.marinum_M TLDTFVSMFRPPFAWREYLLQCWFVARVSTLPGVLMTIPWAVISGFLFNV
MUL_2872|M.ulcerans_Agy99 TLDTFVSMFRPPFAWREYLLQCWFVARVSTLPGVLMTIPWAVISGFLFNV
Rv1964|M.tuberculosis_H37Rv TLDTSVCMFKPPFAWREYLLQCWFVARVSTLPGVLMTIPWAVISGFLFNV
TH_0179|M.thermoresistible__bu SLDTFVQMFRPPFAWREYVHQSWFVARVSVVPALLLTMPYSVLLVFTFNV
Mvan_3984|M.vanbaalenii_PYR-1 SLDTFILMFQRPFAFREYVIQTWFVARVSVLPALMLTMPYSVLLVFTFNI
Mflv_2099|M.gilvum_PYR-GCK ALDTFVAMVKPPFAWREFISQSWFVARVSIVPTLMLTIPYTVLLTFTFNI
MSMEG_0344|M.smegmatis_MC2_155 TLDVFITIARPPFAWREYLNQTWFVARVSLVPALMLTVPYTVLLVFTFNI
MAV_2530|M.avium_104 TLDIFVQLVHPPFAWREFVHQAWFVARVSIAPTILLSIPFNALSVFIINV
Mb3531c|M.bovis_AF2122/97 SMDTARAAFRRPFQFREFLDQTWMVARVSLVPTLLVSIPFTVLVAFTLNI
MAB_4155c|M.abscessus_ATCC_199 SLATFRNIFRRPFQGQEFLDQTWFIARVSLLPTLLVAIPFTVLVAFTLNI
MLBr_02587|M.leprae_Br4923 LVLTGKALFRRPFQWREFILQCWFIMRVAFLPTVMVSIPLTVLLIFTLNV
: : ** :*:: * *:: **: * :::::* .: * :*:
MMAR_2880|M.marinum_M LLTDIGAADFSGTGCAIFTVDQSAPIVTVLVVAGAGATAMCADLGARTIR
MUL_2872|M.ulcerans_Agy99 LLTDIGAADFSGTGCAIFTVDQSAPIVTVLVVAGAGATAMCADLGARTIR
Rv1964|M.tuberculosis_H37Rv LLTDIGAADFSGTGCAIFTVNQSAPIVTVLVVAGAGATAMCADLGARTIR
TH_0179|M.thermoresistible__bu LLAEFGAADYSGTGAAIGTVNQIGPIVTVLVVSGAGATAMCADLGARTIR
Mvan_3984|M.vanbaalenii_PYR-1 LLNEFGASDFSGTGAAIGTVNQIGPIVTVLVVSGAGATAMCADLGARTIR
Mflv_2099|M.gilvum_PYR-GCK LLTEFGAADFSGTGAALGTVRQIGPIVTVLVVAGAGATAMCADLGARTIR
MSMEG_0344|M.smegmatis_MC2_155 LLIEFGAADFSGTGAAIGTVSQIGPIVTVLVVAGAGSTAMCADLGARTIR
MAV_2530|M.avium_104 LLVEIGAADASGAGAALASVAYIGPITTVLVVAGTGATAICADLGARTIR
Mb3531c|M.bovis_AF2122/97 LLREIGAADLSGAGTAFGTITQLGPVVTVLVVAGAGATAICADLGARTIR
MAB_4155c|M.abscessus_ATCC_199 LLREIGAADLSGAATAFGTVTQLGPVVTVLVVAGAGATAICADLGARTIR
MLBr_02587|M.leprae_Br4923 LLAQFSAADLSGAGAAIGAVTQLGPLTTVLVVAGAGSTSICADLGARTIR
** ::.*:* **:. *: :: .*:.*****:*:*:*::**********
MMAR_2880|M.marinum_M EELDALRVMGINPIQALVVPRVLAATTVSLALSSLVIATGLIGAFLCSVF
MUL_2872|M.ulcerans_Agy99 EELDALRVMGINPIQALVVPRVLGATTVSPALSSLVIATGLIGAFLCSVF
Rv1964|M.tuberculosis_H37Rv EELDALRVMGINPIQALAAPRVLAATTVSLALNSVVTATGLIGAFFCSVF
TH_0179|M.thermoresistible__bu EELDALRVMGINPIQALVVPRVLAATTVSLALASTVILVGLVGAFFFVVY
Mvan_3984|M.vanbaalenii_PYR-1 DELDALRVMGINPVQALVVPRVLAATTVALALSASVIIVGLAGAFLFCVY
Mflv_2099|M.gilvum_PYR-GCK EELDALRVMGVNPIQALVVPRVLAATLVSLALSATVILVGLAGAYFFCVY
MSMEG_0344|M.smegmatis_MC2_155 EELDAMRVMGIDPIQALVVPRVLAATTVALALSATVIIVGLAGGFVFAVF
MAV_2530|M.avium_104 EELDAMRVMGINPVQRLLVPRVLALCLNGLLLNSINTIVGLVGSFFFSVY
Mb3531c|M.bovis_AF2122/97 EEIDAMRVLGIDPIQRLVVPRVLASTLVALLLNGLVCAIGLSGGYAFSVF
MAB_4155c|M.abscessus_ATCC_199 EEIDAMQVLGIDPIQRLVVPRVLASTFVALLLNGLVCAIGMVGGYVFSVF
MLBr_02587|M.leprae_Br4923 EEIDAMEVLGIDPIHRLVVPRVLAATLVATLLNGLVITVGLVGGYLFGVY
:*:**:.*:*::*:: * .****. . * . *: *.: *:
MMAR_2880|M.marinum_M LMHVSAGAWVTGLTTLTHTVDVVISMIKATLFGLMAGLIACYKGISVGGG
MUL_2872|M.ulcerans_Agy99 LMHVSAGAWVTGLTTLTHTVDVVISMIKATLFGLMAGLIACYKGISVGGG
Rv1964|M.tuberculosis_H37Rv LMHVSAGAWVTGLTTLTHTVDVVISMIKATLFGLMAGLIACYKGMSVGGG
TH_0179|M.thermoresistible__bu VQHVSAGAFVTGLTLMTGAADVIVSLVKATLFGMAAGLIACYKGISVGGG
Mvan_3984|M.vanbaalenii_PYR-1 VQHVSAGAFISGLTLLTGAGDVVVSLIKATLFGAAAGLIACYKGVYVGGG
Mflv_2099|M.gilvum_PYR-GCK IQNVSPGAFAAGLTLIIGATDVIIALVKAALFGLSAGMIACYKGISVGGG
MSMEG_0344|M.smegmatis_MC2_155 IQHVPPGSFVAGLTVLTHGADVAVALAKAALFGLSAGLIACYKGISVGGG
MAV_2530|M.avium_104 FQHVTPGAWAASLTLLVKIADVAIAFFKAALFGLVAGTIACYKGVTVGGG
Mb3531c|M.bovis_AF2122/97 LQGVNPGAFINGLTVLTGLRELILAEIKALLFGVMAGLVGCYRGLTVKGG
MAB_4155c|M.abscessus_ATCC_199 LQGVNPGAFINGLTVLTGLGELMISEVKAFLFGIFAGLVGCYRGLTVKGG
MLBr_02587|M.leprae_Br4923 LQNVSGGAYLATLTTITGLPEVVIATVKAATFGLIAGLVGCYRGLIVRGG
. * *:: ** : :: :: ** ** ** :.**:*: * **
MMAR_2880|M.marinum_M PAGVGRAVNETVVFAFVVLFVINIVVTAVGIPFMVS-
MUL_2872|M.ulcerans_Agy99 PAGVGRAVNETVVFAFVVLFVINIVVTAVGIPFMVS-
Rv1964|M.tuberculosis_H37Rv PAGVGRAVNETVVFAFIVLFVINIVVTAVGIPFMVS-
TH_0179|M.thermoresistible__bu PAGVGNAVNETVVFSFMVLFAINIVVTAVGIQFTV--
Mvan_3984|M.vanbaalenii_PYR-1 PAGVGNAVNETVVFTFMVLFAINVIVTAVGIQFTVS-
Mflv_2099|M.gilvum_PYR-GCK PAGVGNAVNETVVFTFMALFAINIVATAVAVKVTM--
MSMEG_0344|M.smegmatis_MC2_155 PAGVGNAVNETVVFTFMALFAINVIATAVGVKITVV-
MAV_2530|M.avium_104 PQGVGNAVNETVVYTFMALFVINVVLVAVGTKVTM--
Mb3531c|M.bovis_AF2122/97 PKGVGNAVNETVVYAFICLFVINVVMTAIGVRISAQ-
MAB_4155c|M.abscessus_ATCC_199 PKGVGDAVNETVVYAFICLFVINVVMTAIGVRVLVKH
MLBr_02587|M.leprae_Br4923 SNGLGAAVNETVVLCVVALYAVNVVLTTIGVRFGTGH
. *:* ******* .: *:.:*:: .::. .