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VFPRWPQQAHNHEVSRADTVSVPRAPTQAEVAAVLRIMTPLRKVIKPKVYGIENVPTERALLVGNHNTLG LVDAPLLAAELWERGRIVRSLGDHAHFKIPGWRDALTRTGVVEGTREITSELMRRGELVMVFPGGAREVN KRKNERYKLVWKNRLGFARLAIQHGYPIVPFASVGAEHGIDIVLDNESPLLAPVQFLAEKLLGTKDGPAL VRGVGLTPVPRPERQYYWFGEPIDTTEFMGQQADDNAARRVRERAAAAIEHGIELMLAERAADPNRSLVG RLLRSDA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv1920 | - | - | 100% (287) | PROBABLE MEMBRANE PROTEIN |
| M. tuberculosis H37Rv | Rv0502 | - | 2e-15 | 31.88% (207) | hypothetical protein Rv0502 |
| M. tuberculosis H37Rv | Rv1428c | - | 1e-13 | 25.00% (248) | hypothetical protein Rv1428c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1955 | - | 1e-165 | 99.65% (287) | hypothetical protein Mb1955 |
| M. gilvum PYR-GCK | Mflv_0071 | - | 4e-17 | 33.48% (221) | phospholipid/glycerol acyltransferase |
| M. leprae Br4923 | MLBr_02427 | - | 2e-15 | 32.85% (207) | hypothetical protein MLBr_02427 |
| M. abscessus ATCC 19977 | MAB_4002c | - | 4e-15 | 29.84% (248) | putative acyltransferase |
| M. marinum M | MMAR_2826 | - | 1e-133 | 82.85% (274) | hypothetical protein MMAR_2826 |
| M. avium 104 | MAV_0080 | - | 2e-36 | 40.37% (270) | acyltransferase domain-containing protein |
| M. smegmatis MC2 155 | MSMEG_0947 | - | 2e-14 | 29.32% (249) | acyltransferase |
| M. thermoresistible (build 8) | TH_0953 | - | 4e-16 | 33.66% (205) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_3808 | - | 6e-37 | 39.21% (278) | hypothetical protein MUL_3808 |
| M. vanbaalenii PYR-1 | Mvan_4047 | - | 2e-39 | 39.05% (274) | phospholipid/glycerol acyltransferase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0071|M.gilvum_PYR-GCK -----------MAGEPKAKVIPLHANSGRGAAARRSASQRADSASRHPSV
MSMEG_0947|M.smegmatis_MC2_155 -----------MAGEPKAKVIPLHGNSTRASAARR-AAQKTESARRHPSL
TH_0953|M.thermoresistible__bu ----------VVAGDPKAKVIPLHSDSGR--AAQRRIAQRAASVRRHPSM
MLBr_02427|M.leprae_Br4923 MNSVGWGQVDTVVGETRANVIPLHIKRGR-VASRRRAGYRVDGSRQHPSL
MAB_4002c|M.abscessus_ATCC_199 -----------MAGETKAKVIQLQANSERHAARARRAEARADAGRRHPSS
Rv1920|M.tuberculosis_H37Rv ----------------------------------------------MFPR
Mb1955|M.bovis_AF2122/97 ----------------------------------------------MFPR
MMAR_2826|M.marinum_M --------------------------------------------------
MUL_3808|M.ulcerans_Agy99 -------------------------------------------------M
Mvan_4047|M.vanbaalenii_PYR-1 -------------------------------------------------M
MAV_0080|M.avium_104 -------------------------------------------------M
Mflv_0071|M.gilvum_PYR-GCK LSDPKGRASAEQIASVVREIDQRRGPSSGTGF----DAPPPNELAQRIAA
MSMEG_0947|M.smegmatis_MC2_155 LADPGTRAPAEQIAAVVHEIDQRRLGAAGSG-----AADEPTEIAKSISA
TH_0953|M.thermoresistible__bu QSDAAVQAS-EELAGVIRELESARSGSGRSAA----AQEQPNELARRIGA
MLBr_02427|M.leprae_Br4923 LSDLRGRASAEQIAAVVREIDEHRRSTGATNLWEVTTEAPLSELAQHVAA
MAB_4002c|M.abscessus_ATCC_199 LTNGAPVHDPAETAAVIHDLNEIRAAQGNAHVG---DEESLTALAANIAA
Rv1920|M.tuberculosis_H37Rv WPQQAHNHEVSRADTVSVPRAPTQ------------------------AE
Mb1955|M.bovis_AF2122/97 WPQQAHNHEVSRADTVSVPRAPTQ------------------------AE
MMAR_2826|M.marinum_M ---------MSNVEAPAVPPPPSQ------------------------TD
MUL_3808|M.ulcerans_Agy99 GG----RIDTETIMSPPRRVEFLR------------------------GA
Mvan_4047|M.vanbaalenii_PYR-1 TS----ARHTTEIMNHPARVEALR------------------------GP
MAV_0080|M.avium_104 NSPARQLLSATADDQRARRQAAIE------------------------RA
.
Mflv_0071|M.gilvum_PYR-GCK IAEFVRKRMTGEYTVDEFGFDPHLNDAIFLPLLRVLFNSWFRVEVSGIEN
MSMEG_0947|M.smegmatis_MC2_155 VAEFIRKRMTGDYAVDEFGFDQHLNEAIFLPLLRVFFKSWFRVEVSGIEN
TH_0953|M.thermoresistible__bu VAEFLRKRMTGDYTVDEFGFDPHLNEAVFLPLLRGLFNSWFRVEVSGIEN
MLBr_02427|M.leprae_Br4923 VAGFLRQRLTGDYTVDEFGFDPHFNNAIIRPFLRFFFKSWFRVEVSGIEN
MAB_4002c|M.abscessus_ATCC_199 VAEFIRRRVGGDYSVDDFGFDEHLNESLLLPLLRPLFNRWFRVDVTGVEN
Rv1920|M.tuberculosis_H37Rv VAAVLRIMTP--------------------------LRKVIKPKVYGIEN
Mb1955|M.bovis_AF2122/97 VAAVLRIMTP--------------------------LRKVIKPKVYGIEN
MMAR_2826|M.marinum_M VDAALRIIKP--------------------------LRKLIKPKVYGIEN
MUL_3808|M.ulcerans_Agy99 LDRTQDGIAP--------------------------LIDLFRPHVTGLET
Mvan_4047|M.vanbaalenii_PYR-1 VNVLTRAIEP--------------------------LIDLYRPYVDGLEN
MAV_0080|M.avium_104 LFGLARQWDR--------------------------VRPVYKPYVDGLEN
: . : * *:*.
Mflv_0071|M.gilvum_PYR-GCK LPETGAALVVANHAGVLPFDGLMTQVAVRDEHPAHRDLRLLAADIVFDMP
MSMEG_0947|M.smegmatis_MC2_155 LPDSGAALVVANHAGVLPFDGLMAQVAVHDHHPLHRDLRLLAADLVFDLP
TH_0953|M.thermoresistible__bu LPDSGAALVVANHAGVLPFDGLMASVAVHDHHPLHRDLRMLAADLVFDLP
MLBr_02427|M.leprae_Br4923 LPSTGGALVVANHAGVLPFDGLMLSLAVHDEHPAQRDLRLLVADMVFDLP
MAB_4002c|M.abscessus_ATCC_199 IPATGGALVVANHAGVLPLDGLMLSVAVHDRCPGNRTLRNLAADMVFDAP
Rv1920|M.tuberculosis_H37Rv VP-TERALLVGNHNTLGLVDAPLLAAELWER-GRIVRSLGD--HAHFKIP
Mb1955|M.bovis_AF2122/97 VP-TERALLVGNHNTLGLVDAPLLAAELWER-GRIVRSLGD--HAHFKIP
MMAR_2826|M.marinum_M VP-TEHALLVGNHNTLGMIDAPLLAAELWER-GRLVRSLGD--HAHFRIP
MUL_3808|M.ulcerans_Agy99 LPANGRFLLVGNHTQFVGGEVLLVPHFVRRAIGSRVRPLADRRFG-RSRG
Mvan_4047|M.vanbaalenii_PYR-1 LPRDGRFLLVGNHTQSS-VEGPLIPHYVRREIGTRVRPLTERMMANFPRP
MAV_0080|M.avium_104 LPSDGRFLLVANHSYTPSSEILLLLYEVQRHLGRRVRALMDRRFG-RFAG
:* *:*.** : : :
Mflv_0071|M.gilvum_PYR-GCK MVGQAARKAGHTMACTDDAHRLLAAGELTAVFPEGYKGLGKHFKDRYKLQ
MSMEG_0947|M.smegmatis_MC2_155 MVGQAARKAGHTLACTTDAHRLLANGELTAVFPEGFKGLGKPFKDRYKLQ
TH_0953|M.thermoresistible__bu VVGPAARKAGHTMACAADAHRLLAAGELTAVFPEGYKGLGKRFRDRYKLQ
MLBr_02427|M.leprae_Br4923 VVGEAVRKAGHTVACTSDAHRLLAAGELTAVFPEGYKGLGKRFQDRYRLQ
MAB_4002c|M.abscessus_ATCC_199 FLGQLARKAGHTLACTADAHRLLSGGELTAVFPEGYKGLGKPFKDRYKLQ
Rv1920|M.tuberculosis_H37Rv GWRDALTRTGVVEGTREITSELMRRGELVMVFPGGAREVNKRKNERYKLV
Mb1955|M.bovis_AF2122/97 GWRDALTRTGVVEGTREITSELMRRGELVIVFPGGAREVNKRKNERYKLV
MMAR_2826|M.marinum_M GWREALMRMGVVEGTREITSELMQRGELIMVFPGGGREVNKRKNERYKLV
MUL_3808|M.ulcerans_Agy99 IGYDLMTAYGGVVGAPESARELMRHNETILVFPGGGREIAKFKGEEYHLN
Mvan_4047|M.vanbaalenii_PYR-1 VG-DLLAAYGAVVGSREGTREMMRHNETILVFPGGGREISKFKGEEYTLQ
MAV_0080|M.avium_104 LAADVLAAGGGIVGTREGTAELMRANEPILVFPGGAREIGKGKDQLNTLQ
* . : .:: .* *** * : : * : *
Mflv_0071|M.gilvum_PYR-GCK RFGRGGFVSAALRTKAPIVPCSIVGSEEIYPMIAD----VKLLARLLGLP
MSMEG_0947|M.smegmatis_MC2_155 RFGRGGFVSAALRAKAPIVPCSIVGSEEIYPMIAD----LKLLARLLNLP
TH_0953|M.thermoresistible__bu RFGRGGFVSAALRSKAPIVPCSIVGSEEIYPMLAD----VRLLARLLGVP
MLBr_02427|M.leprae_Br4923 RFGRGGFVKAALSTKATIVPCSIVGSEEIYPMLTD----VKLLARLFGVP
MAB_4002c|M.abscessus_ATCC_199 RFGRGGFVAAAIRTGAPIVPCSIVGSEEIYPMIAD----LKVIARLFGLP
Rv1920|M.tuberculosis_H37Rv WKNRLGFARLAIQHGYPIVPFASVGAEHGIDIVLDNESPLLAPVQFLAEK
Mb1955|M.bovis_AF2122/97 WKNRLGFARLAIQHGYPIVPFASVGAEHGIDIVLDNESPLLAPVQFLAEK
MMAR_2826|M.marinum_M WKNRLGFARLAIQHAYPIVPFASVGAEHGIDIVLDTDSPLMAPTQFLADK
MUL_3808|M.ulcerans_Agy99 WNGRNGFARIAGENDYPIVPVGLVGGDDVYKSMVTRDSALGRLSQAVSVK
Mvan_4047|M.vanbaalenii_PYR-1 WQGRSGFALLCVENDYPIVPVALVGGDDVYSNLLSRGNPLANLTMSLSEK
MAV_0080|M.avium_104 WGDRAGFARLAIEHNYPIVTAAVVGGDDMYKILTTSDGTWAQLNKKVSIW
.* **. . .**. . **.:. : .
Mflv_0071|M.gilvum_PYR-GCK YFP----VTPLFPAAGPLGVVPLPSKWYIQFGEPIDTTDYDESAAEDPMV
MSMEG_0947|M.smegmatis_MC2_155 YFP----VTPFFPLAGPAGMIPLPSKWHIKFGEPIDTQDYDESAADDPMV
TH_0953|M.thermoresistible__bu YFP----ITPLFPAAGPLGLIPLPSKWYIEFGEPIPTADYDESAADDPMI
MLBr_02427|M.leprae_Br4923 YFP----VTPLFPLAGPAGLVPLPSKWRIAFGEPIYTTDYAATDADDPMV
MAB_4002c|M.abscessus_ATCC_199 YFP----VTPLFPAAGPVGLVPLPSKWHIEFGTPIPTDGYDEAAADDPMV
Rv1920|M.tuberculosis_H37Rv LLG-TKDGPALVRGVGLT-PVPRPERQYYWFGEPIDTTEFMGQQADD-NA
Mb1955|M.bovis_AF2122/97 LLG-TKDGPALVRGVGLT-PVPRPERQYYWFGEPIDTTEFMGQQADD-NA
MMAR_2826|M.marinum_M LLG-MREGPPLVRGVGLT-PVPRPERQYYWFGEPIDTTEFAGREADD-SA
MUL_3808|M.ulcerans_Agy99 LTGRSDMAMPLMRGMGPT-LIPRPQRMYLRFGEPIDTTQPDGRAAQE-WV
Mvan_4047|M.vanbaalenii_PYR-1 IFGRGDMTPAILHGIGPT-LIPRPQRMYLRFAEPIDTTKPAAVSTEK-WI
MAV_0080|M.avium_104 LGSDADLLLPLSRGIGPT-LLPRPQRLYARFSRPIDTTRPKGTPHDE-WL
.: * :* *.: *. ** * :.
Mflv_0071|M.gilvum_PYR-GCK TFDLTDQVRETIQQTLYQLLANRRNTFFG---------------------
MSMEG_0947|M.smegmatis_MC2_155 TFELTDQVRETIQHTLYQLLAGRRNMFFG---------------------
TH_0953|M.thermoresistible__bu TFELTDQVRETIQQTLYQLLTRRRSTFLG---------------------
MLBr_02427|M.leprae_Br4923 TFELTDQVRETIQQTLYRLLAGRRNIFFG---------------------
MAB_4002c|M.abscessus_ATCC_199 TFEVTDQVRETIQQTLYRLLAGRRNMFFG---------------------
Rv1920|M.tuberculosis_H37Rv ARRVRERAAAAIEHGIELMLAERAADPNRSLVGRLLRSDA----------
Mb1955|M.bovis_AF2122/97 ARRVRERAAAAIEHGIELMLAERAADPNRSLVGRLLRSDA----------
MMAR_2826|M.marinum_M ARKVRERAAAAIEEGIELMLAERERDPNRSVVRRLLRSDA----------
MUL_3808|M.ulcerans_Agy99 ES-AKKSTQHALETILAELLSIRAGDPFRALNPLSWASAAKAEATSSASQ
Mvan_4047|M.vanbaalenii_PYR-1 AT-VKDRTQRSLEAAISELLQLRRDDPYRELNPLAWRNALEPGSPAPTSA
MAV_0080|M.avium_104 TK-VRETAKTDLESNLAALLAIRATDPFRNLAPWAWRKAVMPHPAQDR--
. . :: : :* *
Mflv_0071|M.gilvum_PYR-GCK -
MSMEG_0947|M.smegmatis_MC2_155 -
TH_0953|M.thermoresistible__bu -
MLBr_02427|M.leprae_Br4923 -
MAB_4002c|M.abscessus_ATCC_199 -
Rv1920|M.tuberculosis_H37Rv -
Mb1955|M.bovis_AF2122/97 -
MMAR_2826|M.marinum_M -
MUL_3808|M.ulcerans_Agy99 N
Mvan_4047|M.vanbaalenii_PYR-1 -
MAV_0080|M.avium_104 -