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MGGRIDTETIMSPPRRVEFLRGALDRTQDGIAPLIDLFRPHVTGLETLPANGRFLLVGNHTQFVGGEVLL VPHFVRRAIGSRVRPLADRRFGRSRGIGYDLMTAYGGVVGAPESARELMRHNETILVFPGGGREIAKFKG EEYHLNWNGRNGFARIAGENDYPIVPVGLVGGDDVYKSMVTRDSALGRLSQAVSVKLTGRSDMAMPLMRG MGPTLIPRPQRMYLRFGEPIDTTQPDGRAAQEWVESAKKSTQHALETILAELLSIRAGDPFRALNPLSWA SAAKAEATSSASQN
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_3808 | - | - | 100% (294) | hypothetical protein MUL_3808 |
| M. ulcerans Agy99 | MUL_4574 | - | 3e-14 | 29.91% (234) | hypothetical protein MUL_4574 |
| M. ulcerans Agy99 | MUL_4347 | - | 1e-10 | 26.52% (264) | hypothetical protein MUL_4347 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1955 | - | 6e-37 | 39.21% (278) | hypothetical protein Mb1955 |
| M. gilvum PYR-GCK | Mflv_0071 | - | 8e-18 | 30.17% (232) | phospholipid/glycerol acyltransferase |
| M. tuberculosis H37Rv | Rv1920 | - | 6e-37 | 39.21% (278) | hypothetical protein Rv1920 |
| M. leprae Br4923 | MLBr_02427 | - | 3e-15 | 29.61% (233) | hypothetical protein MLBr_02427 |
| M. abscessus ATCC 19977 | MAB_4002c | - | 4e-16 | 30.77% (234) | putative acyltransferase |
| M. marinum M | MMAR_3953 | - | 1e-164 | 96.60% (294) | hypothetical protein MMAR_3953 |
| M. avium 104 | MAV_0080 | - | 2e-69 | 49.25% (266) | acyltransferase domain-containing protein |
| M. smegmatis MC2 155 | MSMEG_0947 | - | 2e-16 | 29.74% (232) | acyltransferase |
| M. thermoresistible (build 8) | TH_0953 | - | 1e-15 | 29.58% (240) | CONSERVED HYPOTHETICAL PROTEIN |
| M. vanbaalenii PYR-1 | Mvan_4047 | - | 2e-90 | 56.79% (287) | phospholipid/glycerol acyltransferase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0071|M.gilvum_PYR-GCK -----------MAGEPKAKVIPLHANSGRGAAARRSASQRADSASRHPSV
MSMEG_0947|M.smegmatis_MC2_155 -----------MAGEPKAKVIPLHGNSTRASAARR-AAQKTESARRHPSL
TH_0953|M.thermoresistible__bu ----------VVAGDPKAKVIPLHSDSGR--AAQRRIAQRAASVRRHPSM
MLBr_02427|M.leprae_Br4923 MNSVGWGQVDTVVGETRANVIPLHIKRGR-VASRRRAGYRVDGSRQHPSL
MAB_4002c|M.abscessus_ATCC_199 -----------MAGETKAKVIQLQANSERHAARARRAEARADAGRRHPSS
MUL_3808|M.ulcerans_Agy99 --------------------------------------------------
MMAR_3953|M.marinum_M --------------------------------------------------
Mvan_4047|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_0080|M.avium_104 --------------------------------------------------
Mb1955|M.bovis_AF2122/97 --------------------------------------------------
Rv1920|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_0071|M.gilvum_PYR-GCK LSDPKGRASAEQIASVVREIDQRRGPSSGTGF----DAPPPNELAQRIAA
MSMEG_0947|M.smegmatis_MC2_155 LADPGTRAPAEQIAAVVHEIDQRRLGAAGSG-----AADEPTEIAKSISA
TH_0953|M.thermoresistible__bu QSDAAVQAS-EELAGVIRELESARSGSGRSAA----AQEQPNELARRIGA
MLBr_02427|M.leprae_Br4923 LSDLRGRASAEQIAAVVREIDEHRRSTGATNLWEVTTEAPLSELAQHVAA
MAB_4002c|M.abscessus_ATCC_199 LTNGAPVHDPAETAAVIHDLNEIRAAQGNAHVG---DEESLTALAANIAA
MUL_3808|M.ulcerans_Agy99 -------------------------------------------------M
MMAR_3953|M.marinum_M -------------------------------------------------M
Mvan_4047|M.vanbaalenii_PYR-1 -------------------------------------------------M
MAV_0080|M.avium_104 -------------------------------------------------M
Mb1955|M.bovis_AF2122/97 ----------------------------------------------MFPR
Rv1920|M.tuberculosis_H37Rv ----------------------------------------------MFPR
Mflv_0071|M.gilvum_PYR-GCK IAEFVRKRMTGEYTVDEFGFDPHLNDAIFLPLLRVLFNSWFRVEVSGIEN
MSMEG_0947|M.smegmatis_MC2_155 VAEFIRKRMTGDYAVDEFGFDQHLNEAIFLPLLRVFFKSWFRVEVSGIEN
TH_0953|M.thermoresistible__bu VAEFLRKRMTGDYTVDEFGFDPHLNEAVFLPLLRGLFNSWFRVEVSGIEN
MLBr_02427|M.leprae_Br4923 VAGFLRQRLTGDYTVDEFGFDPHFNNAIIRPFLRFFFKSWFRVEVSGIEN
MAB_4002c|M.abscessus_ATCC_199 VAEFIRRRVGGDYSVDDFGFDEHLNESLLLPLLRPLFNRWFRVDVTGVEN
MUL_3808|M.ulcerans_Agy99 GG----RIDTETIMSPPRRVEFLRGALDRTQDGIAPLIDLFRPHVTGLET
MMAR_3953|M.marinum_M GG----RIDTEAIMSPPRRVEFLRGALDRTQDGIAPLIDLFRPHVTGLET
Mvan_4047|M.vanbaalenii_PYR-1 TS----ARHTTEIMNHPARVEALRGPVNVLTRAIEPLIDLYRPYVDGLEN
MAV_0080|M.avium_104 NSPARQLLSATADDQRARRQAAIERALFGLARQWDRVRPVYKPYVDGLEN
Mb1955|M.bovis_AF2122/97 WPQQAHNHEVSRADTVSVPRAPTQAEVAAVLRIMTPLRKVIKPKVYGIEN
Rv1920|M.tuberculosis_H37Rv WPQQAHNHEVSRADTVSVPRAPTQAEVAAVLRIMTPLRKVIKPKVYGIEN
. : * *:*.
Mflv_0071|M.gilvum_PYR-GCK LPETGAALVVANHAGVLPFDGLMTQVAVRDEHPAHRDLRLLAADIVFDMP
MSMEG_0947|M.smegmatis_MC2_155 LPDSGAALVVANHAGVLPFDGLMAQVAVHDHHPLHRDLRLLAADLVFDLP
TH_0953|M.thermoresistible__bu LPDSGAALVVANHAGVLPFDGLMASVAVHDHHPLHRDLRMLAADLVFDLP
MLBr_02427|M.leprae_Br4923 LPSTGGALVVANHAGVLPFDGLMLSLAVHDEHPAQRDLRLLVADMVFDLP
MAB_4002c|M.abscessus_ATCC_199 IPATGGALVVANHAGVLPLDGLMLSVAVHDRCPGNRTLRNLAADMVFDAP
MUL_3808|M.ulcerans_Agy99 LPANGRFLLVGNHTQFVGGEVLLVPHFVRRAIGSRVRPLADRRFG-RSRG
MMAR_3953|M.marinum_M LPANGRFLLVGNHTQFVGGEVLLVPHFVRRAIGSRVRPLADRRFG-RRRG
Mvan_4047|M.vanbaalenii_PYR-1 LPRDGRFLLVGNHTQSS-VEGPLIPHYVRREIGTRVRPLTERMMANFPRP
MAV_0080|M.avium_104 LPSDGRFLLVANHSYTPSSEILLLLYEVQRHLGRRVRALMDRRFG-RFAG
Mb1955|M.bovis_AF2122/97 VP-TERALLVGNHNTLGLVDAPLLAAELWER-GRIVRSLGD--HAHFKIP
Rv1920|M.tuberculosis_H37Rv VP-TERALLVGNHNTLGLVDAPLLAAELWER-GRIVRSLGD--HAHFKIP
:* *:*.** : : :
Mflv_0071|M.gilvum_PYR-GCK MVGQAARKAGHTMACTDDAHRLLAAGELTAVFPEGYKGLGKHFKDRYKLQ
MSMEG_0947|M.smegmatis_MC2_155 MVGQAARKAGHTLACTTDAHRLLANGELTAVFPEGFKGLGKPFKDRYKLQ
TH_0953|M.thermoresistible__bu VVGPAARKAGHTMACAADAHRLLAAGELTAVFPEGYKGLGKRFRDRYKLQ
MLBr_02427|M.leprae_Br4923 VVGEAVRKAGHTVACTSDAHRLLAAGELTAVFPEGYKGLGKRFQDRYRLQ
MAB_4002c|M.abscessus_ATCC_199 FLGQLARKAGHTLACTADAHRLLSGGELTAVFPEGYKGLGKPFKDRYKLQ
MUL_3808|M.ulcerans_Agy99 IGYDLMTAYGGVVGAPESARELMRHNETILVFPGGGREIAKFKGEEYHLN
MMAR_3953|M.marinum_M FGYDLMTAYGGVVGAPESARELMRHNETILVFPGGGREIAKFKGEEYHLN
Mvan_4047|M.vanbaalenii_PYR-1 VG-DLLAAYGAVVGSREGTREMMRHNETILVFPGGGREISKFKGEEYTLQ
MAV_0080|M.avium_104 LAADVLAAGGGIVGTREGTAELMRANEPILVFPGGAREIGKGKDQLNTLQ
Mb1955|M.bovis_AF2122/97 GWRDALTRTGVVEGTREITSELMRRGELVIVFPGGAREVNKRKNERYKLV
Rv1920|M.tuberculosis_H37Rv GWRDALTRTGVVEGTREITSELMRRGELVMVFPGGAREVNKRKNERYKLV
* . : .:: .* *** * : : * : *
Mflv_0071|M.gilvum_PYR-GCK RFGRGGFVSAALRTKAPIVPCSIVGSEEIYPMIAD--------VKLLARL
MSMEG_0947|M.smegmatis_MC2_155 RFGRGGFVSAALRAKAPIVPCSIVGSEEIYPMIAD--------LKLLARL
TH_0953|M.thermoresistible__bu RFGRGGFVSAALRSKAPIVPCSIVGSEEIYPMLAD--------VRLLARL
MLBr_02427|M.leprae_Br4923 RFGRGGFVKAALSTKATIVPCSIVGSEEIYPMLTD--------VKLLARL
MAB_4002c|M.abscessus_ATCC_199 RFGRGGFVAAAIRTGAPIVPCSIVGSEEIYPMIAD--------LKVIARL
MUL_3808|M.ulcerans_Agy99 WNGRNGFARIAGENDYPIVPVGLVGGDDVYKSMVTRDSALGRLSQAVSVK
MMAR_3953|M.marinum_M WNGRNGFARIAAENDYPIVPVGLVGGDNVYKSMVTRDSTLGRLSQAVSVK
Mvan_4047|M.vanbaalenii_PYR-1 WQGRSGFALLCVENDYPIVPVALVGGDDVYSNLLSRGNPLANLTMSLSEK
MAV_0080|M.avium_104 WGDRAGFARLAIEHNYPIVTAAVVGGDDMYKILTTSDGTWAQLNKKVSIW
Mb1955|M.bovis_AF2122/97 WKNRLGFARLAIQHGYPIVPFASVGAEHGIDIVLDNESPLLAPVQFLAEK
Rv1920|M.tuberculosis_H37Rv WKNRLGFARLAIQHGYPIVPFASVGAEHGIDIVLDNESPLLAPVQFLAEK
.* **. . .**. . **.:. : ::
Mflv_0071|M.gilvum_PYR-GCK LGLPYFPVTPLFPAAGPLGVVPLPSKWYIQFGEPIDTTDYDESAAEDPMV
MSMEG_0947|M.smegmatis_MC2_155 LNLPYFPVTPFFPLAGPAGMIPLPSKWHIKFGEPIDTQDYDESAADDPMV
TH_0953|M.thermoresistible__bu LGVPYFPITPLFPAAGPLGLIPLPSKWYIEFGEPIPTADYDESAADDPMI
MLBr_02427|M.leprae_Br4923 FGVPYFPVTPLFPLAGPAGLVPLPSKWRIAFGEPIYTTDYAATDADDPMV
MAB_4002c|M.abscessus_ATCC_199 FGLPYFPVTPLFPAAGPVGLVPLPSKWHIEFGTPIPTDGYDEAAADDPMV
MUL_3808|M.ulcerans_Agy99 LTGRSDMAMPLMRGMGPT-LIPRPQRMYLRFGEPIDTTQPDGRAAQE-WV
MMAR_3953|M.marinum_M LTGRSDMAMPLMRGMGPT-LIPRPQRMYLRFGEPIDTTQPDGRATQD-WV
Mvan_4047|M.vanbaalenii_PYR-1 IFGRGDMTPAILHGIGPT-LIPRPQRMYLRFAEPIDTTKPAAVSTEK-WI
MAV_0080|M.avium_104 LGSDADLLLPLSRGIGPT-LLPRPQRLYARFSRPIDTTRPKGTPHDE-WL
Mb1955|M.bovis_AF2122/97 LLG-TKDGPALVRGVGLT-PVPRPERQYYWFGEPIDTTEFMGQQADD-NA
Rv1920|M.tuberculosis_H37Rv LLG-TKDGPALVRGVGLT-PVPRPERQYYWFGEPIDTTEFMGQQADD-NA
: .: * :* *.: *. ** * :.
Mflv_0071|M.gilvum_PYR-GCK TFDLTDQVRETIQQTLYQLLANRRNTFFG---------------------
MSMEG_0947|M.smegmatis_MC2_155 TFELTDQVRETIQHTLYQLLAGRRNMFFG---------------------
TH_0953|M.thermoresistible__bu TFELTDQVRETIQQTLYQLLTRRRSTFLG---------------------
MLBr_02427|M.leprae_Br4923 TFELTDQVRETIQQTLYRLLAGRRNIFFG---------------------
MAB_4002c|M.abscessus_ATCC_199 TFEVTDQVRETIQQTLYRLLAGRRNMFFG---------------------
MUL_3808|M.ulcerans_Agy99 ES-AKKSTQHALETILAELLSIRAGDPFRALNPLSWASAAKAEATSSASQ
MMAR_3953|M.marinum_M ES-VKKSTQHALETILAELLSIRAGDPFRALNPLSWASAAKAEATSIASQ
Mvan_4047|M.vanbaalenii_PYR-1 AT-VKDRTQRSLEAAISELLQLRRDDPYRELNPLAWRNALEPGSPAPTSA
MAV_0080|M.avium_104 TK-VRETAKTDLESNLAALLAIRATDPFRNLAPWAWRKAVMPHPAQDR--
Mb1955|M.bovis_AF2122/97 ARRVRERAAAAIEHGIELMLAERAADPNRSLVGRLLRSDA----------
Rv1920|M.tuberculosis_H37Rv ARRVRERAAAAIEHGIELMLAERAADPNRSLVGRLLRSDA----------
. . :: : :* *
Mflv_0071|M.gilvum_PYR-GCK -
MSMEG_0947|M.smegmatis_MC2_155 -
TH_0953|M.thermoresistible__bu -
MLBr_02427|M.leprae_Br4923 -
MAB_4002c|M.abscessus_ATCC_199 -
MUL_3808|M.ulcerans_Agy99 N
MMAR_3953|M.marinum_M N
Mvan_4047|M.vanbaalenii_PYR-1 -
MAV_0080|M.avium_104 -
Mb1955|M.bovis_AF2122/97 -
Rv1920|M.tuberculosis_H37Rv -