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SETDSPGNGDDAGIGDIGKFDPGLTQRLISVLRPVLKTYHRSQVHGLDSFPPGGALVVANHSGGMFPMDV PVFSVDFYDKFGYDRPVYTLSHDILFMGLTGDLFRRTGYIRATRENAAKALRSGGVVVVFPGGDYDAYRP TFAENVIDFNGRKGYVSTAVEAGVPIVPAVSIGGQESQLYLSRGTWLARRLGLKRLLRSDILPISFGFPF GFSAAIPPNLPLPAKIVMQVLDPINLTKQFGEDPDVDAVDEHVRSVMQQALNDLAAKRRFPILG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv1428c | - | - | 100% (275) | hypothetical protein Rv1428c |
| M. tuberculosis H37Rv | Rv0502 | - | 6e-21 | 31.84% (267) | hypothetical protein Rv0502 |
| M. tuberculosis H37Rv | Rv1920 | - | 1e-13 | 25.00% (248) | hypothetical protein Rv1920 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1463c | - | 1e-159 | 100.00% (275) | hypothetical protein Mb1463c |
| M. gilvum PYR-GCK | Mflv_0434 | - | 3e-99 | 64.62% (260) | phospholipid/glycerol acyltransferase |
| M. leprae Br4923 | MLBr_02427 | - | 4e-20 | 31.01% (258) | hypothetical protein MLBr_02427 |
| M. abscessus ATCC 19977 | MAB_4002c | - | 1e-23 | 32.85% (274) | putative acyltransferase |
| M. marinum M | MMAR_2234 | - | 1e-132 | 86.49% (259) | hypothetical protein MMAR_2234 |
| M. avium 104 | MAV_3346 | - | 1e-130 | 82.77% (267) | acyltransferase domain-containing protein |
| M. smegmatis MC2 155 | MSMEG_0305 | - | 1e-105 | 66.79% (265) | acyltransferase domain-containing protein |
| M. thermoresistible (build 8) | TH_1905 | - | 1e-103 | 66.80% (259) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_1821 | - | 1e-132 | 86.10% (259) | hypothetical protein MUL_1821 |
| M. vanbaalenii PYR-1 | Mvan_0233 | - | 1e-100 | 64.53% (265) | phospholipid/glycerol acyltransferase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0434|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0233|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0305|M.smegmatis_MC2_155 --------------------------------------------------
TH_1905|M.thermoresistible__bu --------------------------------------------------
Rv1428c|M.tuberculosis_H37Rv --------------------------------------------------
Mb1463c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_2234|M.marinum_M --------------------------------------------------
MUL_1821|M.ulcerans_Agy99 --------------------------------------------------
MAV_3346|M.avium_104 --------------------------------------------------
MLBr_02427|M.leprae_Br4923 MNSVGWGQVDTVVGETRANVIPLHIKRGRVASR-RRAGYRVDGSRQHPSL
MAB_4002c|M.abscessus_ATCC_199 -----------MAGETKAKVIQLQANSERHAARARRAEARADAGRRHPSS
Mflv_0434|M.gilvum_PYR-GCK -----------------------------------------------MGA
Mvan_0233|M.vanbaalenii_PYR-1 -----------------------------------------------MSA
MSMEG_0305|M.smegmatis_MC2_155 -----------------------------------------------MAA
TH_1905|M.thermoresistible__bu -----------------------------------------------LSP
Rv1428c|M.tuberculosis_H37Rv -----------------------------------------------MSE
Mb1463c|M.bovis_AF2122/97 -----------------------------------------------MSE
MMAR_2234|M.marinum_M -----------------------------------------------MSD
MUL_1821|M.ulcerans_Agy99 -----------------------------------------------MSD
MAV_3346|M.avium_104 -----------------------------------------------MTD
MLBr_02427|M.leprae_Br4923 LSDLRGRASAEQIAAVVREIDEHRRSTGATNLWEVTTEAPLSELAQHVAA
MAB_4002c|M.abscessus_ATCC_199 LTNGAPVHDPAETAAVIHDLNEIRAAQGNA---HVGDEESLTALAANIAA
:
Mflv_0434|M.gilvum_PYR-GCK SD-------KIPSEITKW--DPALTERVMG-LLKPFLKGWHRAEVRGLDD
Mvan_0233|M.vanbaalenii_PYR-1 TD-------IDTSEITKW--DPVLTERVMG-LLKPFLKGWHRAEVRGLED
MSMEG_0305|M.smegmatis_MC2_155 TD-------TDPGEITKW--DPGLTEKVMG-WLRPLIKGYHRAEVHGLDT
TH_1905|M.thermoresistible__bu TD-------IEPSEIAKW--DPDLTERVMG-LLRPLIKGYHRAEIRGLDT
Rv1428c|M.tuberculosis_H37Rv TDSPGNGDDAGIGDIGKF--DPGLTQRLIS-VLRPVLKTYHRSQVHGLDS
Mb1463c|M.bovis_AF2122/97 TDSPGNGDDAGIGDIGKF--DPGLTQRLIS-VLRPVLKTYHRSQVHGLDS
MMAR_2234|M.marinum_M TD-----NDK---DIEKF--DPGLTRRMIG-VMRPVVKTYFRSEVHGLDS
MUL_1821|M.ulcerans_Agy99 TD-----NDK---DIEKF--DPGLTRRMIG-VMRPVVKTYFRSEVHGLDS
MAV_3346|M.avium_104 SD------NADGGDIGKF--DPVLTQRLMT-VMRPVLKAYFRSEVHGLES
MLBr_02427|M.leprae_Br4923 VAGFLRQRLTGDYTVDEFGFDPHFNNAIIRPFLRFFFKSWFRVEVSGIEN
MAB_4002c|M.abscessus_ATCC_199 VAEFIRRRVGGDYSVDDFGFDEHLNESLLLPLLRPLFNRWFRVDVTGVEN
: .: * :.. :: :: ..: :.* :: *::
Mflv_0434|M.gilvum_PYR-GCK FPA-GGALVVSNHSGGLFPMDVPVFASGFYDKFGFDRPVYTLSHDMLMVG
Mvan_0233|M.vanbaalenii_PYR-1 FPN-GGALVVANHSGGLFPMDVPIFASGFYEKFGYDRPVYTLSHDMLMVG
MSMEG_0305|M.smegmatis_MC2_155 FPN-GGALVVSNHSGGLFPMDVPVFATGFYEKFGYDRPVYTLSHDMLMTG
TH_1905|M.thermoresistible__bu FPH-GGALVVSNHSGGLFPMDVPVFATGFYERFGYDRPVYTLSHDILLTG
Rv1428c|M.tuberculosis_H37Rv FPP-GGALVVANHSGGMFPMDVPVFSVDFYDKFGYDRPVYTLSHDILFMG
Mb1463c|M.bovis_AF2122/97 FPP-GGALVVANHSGGMFPMDVPVFSVDFYDKFGYDRPVYTLSHDILFMG
MMAR_2234|M.marinum_M FPP-GGALVVGNHSGGMFPMDVPIFSVDFYDKFGYDRPVYTLSHDILFMG
MUL_1821|M.ulcerans_Agy99 FPP-GGALVVGNHSGGMFPMDVPIFSVDFYDKFGYDRPVYTLSHDILFMG
MAV_3346|M.avium_104 FPP-GGALVVGNHSGGMFPMDVPIFSVHFYDKYGYDRPIYTLSHDILMTG
MLBr_02427|M.leprae_Br4923 LPSTGGALVVANHAG-VLPFDGLMLSLAVHDEHPAQRDLRLLVADMVFDL
MAB_4002c|M.abscessus_ATCC_199 IPATGGALVVANHAG-VLPLDGLMLSVAVHDRCPGNRTLRNLAADMVFDA
:* ******.**:* ::*:* ::: .::. :* : * *:::
Mflv_0434|M.gilvum_PYR-GCK -PTGAFFKKTGFIPANHKNADEALRSGGVVVVFPGGDYDVYRPSLAANKI
Mvan_0233|M.vanbaalenii_PYR-1 -PTGAFFKKTGFIPANHRNADEALRSGGVVVVFPGGDYDVYRPTLAANKI
MSMEG_0305|M.smegmatis_MC2_155 -PTADFFKKTGFIRANHENADEALRSGGVVVVFPGGDYDVYRPTLAANKI
TH_1905|M.thermoresistible__bu -PTADFFIRTGFIRANHDNADEALRSGGVVIVFPGGDYDVYRPTFAQHKI
Rv1428c|M.tuberculosis_H37Rv -LTGDLFRRTGYIRATRENAAKALRSGGVVVVFPGGDYDAYRPTFAENVI
Mb1463c|M.bovis_AF2122/97 -LTGDLFRRTGYIRATRENAAKALRSGGVVVVFPGGDYDAYRPTFAENVI
MMAR_2234|M.marinum_M -ATGSFFRRTGYIRASRDNAAKALRSGGVVIVFPGGDYDAYRPTLSENVI
MUL_1821|M.ulcerans_Agy99 -ATGSFFRRTGYIRASRDNAAKALRSGGVVIVFPGGDYDAYRPTLSENVI
MAV_3346|M.avium_104 -PTGDFFRRTGYIRANRENAAAALRSGGVVIVFPGGDYDAYRPTLAENVI
MLBr_02427|M.leprae_Br4923 PVVGEAVRKAGHTVACTSDAHRLLAAGELTAVFPEGYKGLGKRFQDRYRL
MAB_4002c|M.abscessus_ATCC_199 PFLGQLARKAGHTLACTADAHRLLSGGELTAVFPEGYKGLGKPFKDRYKL
. ::*. * :* * .* :. *** * . : :
Mflv_0434|M.gilvum_PYR-GCK DFGGRTGYVRAALNAGVPIVPTVGIGGQESQLFLARGTDLAKALGPIAKL
Mvan_0233|M.vanbaalenii_PYR-1 DFGGRTGYVKAAINAGVPIVPTVAIGGQESQLFLSRGTELAKALGPVARA
MSMEG_0305|M.smegmatis_MC2_155 DFAGRTGYVRAALNAGVPIVPMVGVGGQETQLFLSRGTAVAKALGPIARL
TH_1905|M.thermoresistible__bu DFDGRTGYVRAALNAGVPIVPTVAVGGQESQLFLSRGESLARLLR-LDKL
Rv1428c|M.tuberculosis_H37Rv DFNGRKGYVSTAVEAGVPIVPAVSIGGQESQLYLSRGTWLARRLG-LKRL
Mb1463c|M.bovis_AF2122/97 DFNGRKGYVSTAVEAGVPIVPAVSIGGQESQLYLSRGTWLARRLG-LKRL
MMAR_2234|M.marinum_M DFNGRKGYVSTAIEAGVPIVPAVSIGGQETQLYLSRGTWLAERLG-LKRL
MUL_1821|M.ulcerans_Agy99 DFNGRKGYVSTAIEAGVPIVPAVSIGGQETQLYLSRGTWLAERLG-LKRL
MAV_3346|M.avium_104 DFDGRKGYVRTAIEAGVPIVPAVSIGGQETQLYLTRGTWLAERLG-IKRL
MLBr_02427|M.leprae_Br4923 QRFGRGGFVKAALSTKATIVPCSIVGSEEIYPMLTDVKLLARLFG-----
MAB_4002c|M.abscessus_ATCC_199 QRFGRGGFVAAAIRTGAPIVPCSIVGSEEIYPMIADLKVIARLFG-----
: ** *:* :*: : ..*** :*.:* :: :*. :
Mflv_0434|M.gilvum_PYR-GCK ARTKIIPVSFGFPFGLSVVLPLNVPLPAKITMKALPPIDIVEEFGEDPD-
Mvan_0233|M.vanbaalenii_PYR-1 FRTKILPVSFGFPFGLSVVLPLNVPLPAKITMKALPPIDIVAEFGEDPD-
MSMEG_0305|M.smegmatis_MC2_155 ARTKIVPVSFGFPFGLSAVLPLNVPLPSKIVMKTLPPIDITAEFGEDPD-
TH_1905|M.thermoresistible__bu MRVKILPISFGFPWGLSAVVPVNVPLPTKIVMQVLPPIDIEAEFGPDPD-
Rv1428c|M.tuberculosis_H37Rv LRSDILPISFGFPFGFSAAIPPNLPLPAKIVMQVLDPINLTKQFGEDPD-
Mb1463c|M.bovis_AF2122/97 LRSDILPISFGFPFGFSAAIPPNLPLPAKIVMQVLDPINLTKQFGEDPD-
MMAR_2234|M.marinum_M LRSDILPLSFGFPFGFSAAIPPNLPLPTKIVTEVLDPIDVIAQFGEDPD-
MUL_1821|M.ulcerans_Agy99 LRSDILPLSFGFPFGISAAIPPNLPLPTKIVTEVLDPIDVIVQFGEDPD-
MAV_3346|M.avium_104 LRSAILPVSFGFPFGLSAVIPPNLPLPAKIVTRVLDPIDIAKQFGEDPD-
MLBr_02427|M.leprae_Br4923 --VPYFPVTPLFPLAGPAGL---VPLPSKWRIAFGEPIYTTDYAATDADD
MAB_4002c|M.abscessus_ATCC_199 --LPYFPVTPLFPAAGPVGL---VPLPSKWHIEFGTPIPTDGYDEAAADD
.*:: ** . .. : :***:* ** .*
Mflv_0434|M.gilvum_PYR-GCK ---IDEVDAHVRRVMQRALDELAQERKLPILG
Mvan_0233|M.vanbaalenii_PYR-1 ---IDEVDAHVRRVMQRALDELAQERRLPVLG
MSMEG_0305|M.smegmatis_MC2_155 ---IDEVDAHVRHVMQQALDELAEQRRFPVIG
TH_1905|M.thermoresistible__bu ---IDEVDAHVRRTMQRALDELAAERRLPVLG
Rv1428c|M.tuberculosis_H37Rv ---VDAVDEHVRSVMQQALNDLAAKRRFPILG
Mb1463c|M.bovis_AF2122/97 ---VDAVDEHVRSVMQQALNDLAAKRRFPILG
MMAR_2234|M.marinum_M ---VDQVDQHVRSVMQEALTRLAATRRFPILG
MUL_1821|M.ulcerans_Agy99 ---VDQVDQHVRSVMQEALTRLAATRRFPILG
MAV_3346|M.avium_104 ---VDEVDEYVRSVMQQALNELAAERRFPILG
MLBr_02427|M.leprae_Br4923 PMVTFELTDQVRETIQQTLYRLLAGRRNIFFG
MAB_4002c|M.abscessus_ATCC_199 PMVTFEVTDQVRETIQQTLYRLLAGRRNMFFG
: ** .:*.:* * *: .:*