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M. tuberculosis H37Rv Rv1916 (aceAb)

annotation: isocitrate lyase
coordinates: 2161566 - 2162762
length: 398

MTYGEAVADVLEFGQSEGEPIGMAPEEWRAFAARASLHAARAKAKELGADPPWDCELAKTPEGYYQIRGG
IPYAIAKSLAAAPFADILWMETKTADLADARQFAEAIHAEFPDQMLAYNLSPSFNWDTTGMTDEEMRRFP
EELGKMGFVFNFITYGGHQIDGVAAEEFATALRQDGMLALARLQRKMRLVESPYRTPQTLVGGPRSDAAL
AASSGRTATTKAMGKGSTQHQHLVQTEVPRKLLEEWLAMWSGHYQLKDKLRVQLRPQRAGSEVLELGIHG
ESDDKLANVIFQPIQDRRGRTILLVRDQNTFGAELRQKRLMTLIHLWLVHRFKAQAVHYVTPTDDNLYQT
SKMKSHGIFTEVNQEVGEIIVAEVNHPRIAELLTPDRVALRKLITKEA
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv1916aceAb-100% (398)isocitrate lyase
M. tuberculosis H37RvRv0467icl6e-2841.42% (169) isocitrate lyase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1950aceA0.0100.00% (398) isocitrate lyase
M. gilvum PYR-GCKMflv_3260-0.079.04% (396) isocitrate lyase
M. leprae Br4923MLBr_01985aceA0.087.91% (397) isocitrate lyase
M. abscessus ATCC 19977MAB_4095c-9e-2840.80% (174) isocitrate lyase (AceA)
M. marinum MMMAR_2821aceAb0.088.38% (396) isocitrate lyase AceAb
M. avium 104MAV_2781aceA0.087.15% (397) isocitrate lyase
M. smegmatis MC2 155MSMEG_3706aceA0.078.95% (399) isocitrate lyase
M. thermoresistible (build 8)TH_0417aceAb0.080.75% (400) PROBABLE ISOCITRATE LYASE aceAb
M. ulcerans Agy99MUL_2943aceAb0.087.63% (396) isocitrate lyase AceAb
M. vanbaalenii PYR-1Mvan_2977-0.078.79% (396) isocitrate lyase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_3260|M.gilvum_PYR-GCK          ------------------------------------MAITEADLQS----
Mvan_2977|M.vanbaalenii_PYR-1       ------------------------------------MAIIEADAFQPHAT
MSMEG_3706|M.smegmatis_MC2_155      ------------------------------------MATIEANAHNLSSS
Rv1916|M.tuberculosis_H37Rv         --------------------------------------------------
Mb1950|M.bovis_AF2122/97            ------------------------------------MAIAETDTEVHTPF
MMAR_2821|M.marinum_M               ------------------------------------MAIAETDTEVRTP-
MUL_2943|M.ulcerans_Agy99           ------------------------------------MAIVETDTEIRTP-
MLBr_01985|M.leprae_Br4923          MAGIPATVVQRCNSTNLDDRLHYSPLGDRAKEERNPMAIMDTNTEVHTL-
MAV_2781|M.avium_104                ------------------------------------MAIIDKETQVRPS-
TH_0417|M.thermoresistible__bu      ------------------------------------MAISEAERETRTS-
MAB_4095c|M.abscessus_ATCC_199      ------------------------------------MSNVGK--------
                                                                                      

Mflv_3260|M.gilvum_PYR-GCK          QTPFERDVVETQRYFDS-PRFEGIIRLYTARQVAEQRGTIPADYPVAREA
Mvan_2977|M.vanbaalenii_PYR-1       GEPFERDVAETQRYFDS-PRFDGITRLYTARQVAEQRGTIPADYPTAREA
MSMEG_3706|M.smegmatis_MC2_155      AKDFDSEVAATQAYFDS-PRFEGITRLYSARQVVEQRGTIATDHTVAREA
Rv1916|M.tuberculosis_H37Rv         --------------------------------------------------
Mb1950|M.bovis_AF2122/97            EQDFEKDVAATQRYFDS-SRFAGIIRLYTARQVVEQRGTIPVDHIVAREA
MMAR_2821|M.marinum_M               ---FEQEVADTQRYFDS-SRFAGIVRLYTARQVVEQRGTIPNDYTVARTA
MUL_2943|M.ulcerans_Agy99           ---FEQEVADTQRYFDS-SRFAGIVRLYTARQVVEQRGTIPNDYTVARTA
MLBr_01985|M.leprae_Br4923          ---FTQEVAATQQYFDD-PRFAGIIRLYTARQVVEQRGTIPTDYTVARDA
MAV_2781|M.avium_104                ---FDDEVAATQRYFDD-PRFARITRLYTARQVAEQRGTIRTDYTVARDA
TH_0417|M.thermoresistible__bu      ---FEEDVAETQRYFDS-PRFDGIIRLYTARQVVEQRGTIPVDYTIAREA
MAB_4095c|M.abscessus_ATCC_199      ----PRTAAEIQQDWDTNPRWKGITRDYTAAQVEELQGSVVEENTLARRG
                                                                                      

Mflv_3260|M.gilvum_PYR-GCK          ATAFFPHLRELFGQGRSITTFGPYSPGQAVVMKRMGIEGIYLGGWATSAK
Mvan_2977|M.vanbaalenii_PYR-1       ATAFYPHLRELFAKGKSITTFGPYSPGQAVVMKRMGIEGVYLGGWATSAK
MSMEG_3706|M.smegmatis_MC2_155      AEAFHPYLRELFAQKKSITTFGPYSPGQAVVMKRMGIGGIYLGGWATSAK
Rv1916|M.tuberculosis_H37Rv         --------------------------------------------------
Mb1950|M.bovis_AF2122/97            AGAFYERLRELFAARKSITTFGPYSPGQAVSMKRMGIEAIYLGGWATSAK
MMAR_2821|M.marinum_M               AGAFYQRLRELYAEKKSVTTFGPYSPGQAVSMKRMGIEAIYLGGWATSAK
MUL_2943|M.ulcerans_Agy99           AGVFYQRLRELYAEKKSVTTFGPYSPGQAVSMKRMGIEAIYLGGWATSAK
MLBr_01985|M.leprae_Br4923          ATAFYARLRELFAAGKSVTTFGPYSPGQAVSLKRMGIEAIYLGGWATSAK
MAV_2781|M.avium_104                AAAFYERLRELFAQKKSITTFGPYSPGQAVTMKRMGIEGIYLGGWATSAK
TH_0417|M.thermoresistible__bu      ATAFYARLRELFAERKCITTFGPYSPGQAVTMKRMGIEGIYLGGWATSAK
MAB_4095c|M.abscessus_ATCC_199      AEILWDAVSK--DDDSYINALGALTGNMAVQQVRAGLKAIYLSGWQVAGD
                                                                                      

Mflv_3260|M.gilvum_PYR-GCK          GSISEDPGPDLASYPLSQVPEEAAGIVRALLTADRNQQYLRLQMTPEQQA
Mvan_2977|M.vanbaalenii_PYR-1       GSISEDPGPDLASYPLSQVPEEAASIVRALLTADRNQHYLRLQMDPEQRA
MSMEG_3706|M.smegmatis_MC2_155      GSISEDPGPDLASYPLSQVPDEAAGLVRALLTADRNQHYLRLQMTPEQRE
Rv1916|M.tuberculosis_H37Rv         --------------------------------------------------
Mb1950|M.bovis_AF2122/97            GSSTEDPGPDLASYPLSQVPDDAAVLVRALLTADRNQHYLRLQMSERQRA
MMAR_2821|M.marinum_M               GSTTEDPGPDLASYPLSQVPDDAAVLVRALLTADRNQEYLRLQMTDQQRA
MUL_2943|M.ulcerans_Agy99           GSTTEDPGPDLASYPLSQVPDDAAVLVRALLTADRNQEYLRLQMTDQQRA
MLBr_01985|M.leprae_Br4923          GSITEDPGPDLASYPLSQVPDDAAVLVRALLAADRNQQYLRLHMTEQQRA
MAV_2781|M.avium_104                GSTTEDPGPDLASYPLSQVPDDAAVLVRALLTADRNQQYLRLQMSEQQRA
TH_0417|M.thermoresistible__bu      GSADEDPGPDLASYPLSQVPNEAAGLVRALLTADRNQEYLRQRMSPEQRA
MAB_4095c|M.abscessus_ATCC_199      ANLSGHTYPDQSLYPANSVPAVVRRINNALLRADEIAR---------VEG
                                                                                      

Mflv_3260|M.gilvum_PYR-GCK          TTPAYDYRPFIIADADTGHGGDPHVRNLIRRFVENGVPGYHIEDQRPGTK
Mvan_2977|M.vanbaalenii_PYR-1       AAPEYDYRPFIIADADTGHGGDPHVRNLIRRFVEAGVPGYHIEDQRPGTK
MSMEG_3706|M.smegmatis_MC2_155      AQPPVDYRPFIIADADTGHGGDPHVRNLIRRFVESGVPGYHIEDQRPGTK
Rv1916|M.tuberculosis_H37Rv         --------------------------------------------------
Mb1950|M.bovis_AF2122/97            ATPAYDFRPFIIADADTGHGGDPHVRNLIRRFVEVGVPGYHIEDQRPGTK
MMAR_2821|M.marinum_M               TTTAYDFRPFIIADADTGHGGDPHVRNLIRRFVEVGVPGYHIEDQRPGTK
MUL_2943|M.ulcerans_Agy99           TTTAYDFRPFIIADADTGHGGDPHVRNLIRRFVEVGVPGYHIEDQRPGTK
MLBr_01985|M.leprae_Br4923          ATPAYDYRPFIIADADTGHGGDSHVRNLIRRFVEIGVPGYHIEDQRPGTK
MAV_2781|M.avium_104                ATKEYDYRPFIIADADTGHGGDPHVRNLIRRFVEVGVPGYHIEDQRPGTK
TH_0417|M.thermoresistible__bu      ATPVYDYRPFIIADADTGHGGDAHVRNLIRRFVEAGVAGYHIEDQRPGTK
MAB_4095c|M.abscessus_ATCC_199      DTSVDNWLVPIVADGEAGFGGALNVYELQKAMIAAGAAGTHWEDQLASEK
                                                                                      

Mflv_3260|M.gilvum_PYR-GCK          KCGHQGGKVLVPSDEQIKRLNTARFQLDIMRVPGIIVARTDAEAANLIDS
Mvan_2977|M.vanbaalenii_PYR-1       KCGHQGGKVLVPSDEQIKRLNTARFQLDIMRVPGIIVARTDAEAANLIDS
MSMEG_3706|M.smegmatis_MC2_155      KCGHQGGKVLVPSDEQIKRLNTARFQLDIMRVPGIIVARTDAEAANLIDS
Rv1916|M.tuberculosis_H37Rv         --------------------------------------------------
Mb1950|M.bovis_AF2122/97            KCGHQGGKVLVPSDEQIKRLNAARFQLDIMRVPGIIVARTDAEAANLIDS
MMAR_2821|M.marinum_M               KCGHQGGKVLVPSDEQIKRLNAARFQLDVMRVPGIIVARTDAEAANLIDS
MUL_2943|M.ulcerans_Agy99           KCGHQGGKVLVPSDEQIKRLNAARFQLDVMRVPGIIVARTDAEAANLIDS
MLBr_01985|M.leprae_Br4923          KCGHQGGKVLVPSDEQIKRLNAARFQLDIMRVPGIIVARTDAEAANLIDS
MAV_2781|M.avium_104                KCGHQGGKVLVPSDEQIKRLNAARFQLDIMRVPGIIVARTDAEAANLLDS
TH_0417|M.thermoresistible__bu      KCGHQGGKVLVPSDEQIKRLNTARFQLDIMRVPGIIVARTDAEAANLIDS
MAB_4095c|M.abscessus_ATCC_199      KCGHLGGKVLIPTQQHIRTLTSARLAADVANTPTVVIARTDAEAATLITS
                                                                                      

Mflv_3260|M.gilvum_PYR-GCK          RADERDQPFLLGATNLKIPSYKSCYLAMMRRFYDKGVTELNGHLLYALPD
Mvan_2977|M.vanbaalenii_PYR-1       RADERDQPFLLGATNLKIPSYKSCFLAMVRRFYEKGMTELNGHLLYALPE
MSMEG_3706|M.smegmatis_MC2_155      RADERDQPFLLGVTNLKIPSYKSCFLAMMRRFYDQGLTEINGHLLYDLPE
Rv1916|M.tuberculosis_H37Rv         --------------------------------------------------
Mb1950|M.bovis_AF2122/97            RADERDQPFLLGATKLDVPSYKSCFLAMVRRFYELGVKELNGHLLYALGD
MMAR_2821|M.marinum_M               RADERDQPFLLGATKLDIPSYKSCFLAMLRRFYELGVKELNGHLLYALAD
MUL_2943|M.ulcerans_Agy99           RADERDQPFLLGATKLDIPSYKSCFLAMLRRFYELGVKELNGHLLYALAD
MLBr_01985|M.leprae_Br4923          RADERDQPFLLGATNLKIPSYKACFLALVRCFYELGVKELHGHLLYALGD
MAV_2781|M.avium_104                RADERDQPFLLGATNLDIPSYKACFLAMVRRFYELGVKDLNGHLLYALPE
TH_0417|M.thermoresistible__bu      RADERDQPFLLGATNLAIPSYKSCYLAMLRSFYDSGVTELNGHLLYWLAE
MAB_4095c|M.abscessus_ATCC_199      DVDERDKPFVTG--------------------------------------
                                                                                      

Mflv_3260|M.gilvum_PYR-GCK          GEYATAEAWLQRQGVLDLVDQTAAAWQDGTEASLDTAFDKVESRFVEAWQ
Mvan_2977|M.vanbaalenii_PYR-1       GEYATATAWLDRQGVLNLIDETASAWQAGTESSVDAAFDRVESRFVDAWQ
MSMEG_3706|M.smegmatis_MC2_155      GQYEAAEAWLTGAGIMDEIAAAVESWTSGAASSVDALYDAVESKFVDAWQ
Rv1916|M.tuberculosis_H37Rv         --------------------------------------------------
Mb1950|M.bovis_AF2122/97            SEYAAAGGWLERQGIFGLVSDAVNAWREDGQQSIDGIFDQVESRFVAAWE
MMAR_2821|M.marinum_M               AEYAAANGWLERSGIMSLISDAVNSWREDGMQTIDDLFDQVESRFVAAWE
MUL_2943|M.ulcerans_Agy99           AEYAAANGWLERSGIMGLISDAVNSWREDGMQTTDDLFDQVESRFVAAWE
MLBr_01985|M.leprae_Br4923          GEYAAASAWLDRQGILAQVSGTVNAWQENGKQSIDDLFEQVEYRLLAAWE
MAV_2781|M.avium_104                AEYAEATAWLERQGIQGVISDAVNTWRENGQQSIDDLFDQVESRFVAAWE
TH_0417|M.thermoresistible__bu      GEYDRARAWLDRNGLLDRISEAVGKWRPGEDPANDELFDEVESAFVEIWE
MAB_4095c|M.abscessus_ATCC_199      --------------------------------------------------
                                                                                      

Mflv_3260|M.gilvum_PYR-GCK          DDAGLNTYGEAVAELLEFREREGEPSPMSVAQWREFAERAPLYTAREKAK
Mvan_2977|M.vanbaalenii_PYR-1       DDAGLNTYGEAVAELLEFREREGEPSSMSVADWRMFAERAPLYTAREKAK
MSMEG_3706|M.smegmatis_MC2_155      DDAGLNTYGEAVAEVIEFREREGESVAMSAAEWREFATRAPLYTATNKAR
Rv1916|M.tuberculosis_H37Rv         -----MTYGEAVADVLEFGQSEGEPIGMAPEEWRAFAARASLHAARAKAK
Mb1950|M.bovis_AF2122/97            DDAGLMTYGEAVADVLEFGQSEGEPIGMAPEEWRAFAARASLHAARAKAK
MMAR_2821|M.marinum_M               DDAGLMTYAEAVAEVLAFGQSEGDPVAMSPEEWRTFAARASLYAARQKAK
MUL_2943|M.ulcerans_Agy99           DDAGLMTYAEAVAEVLAFGQSEGDPVPMSPEEWRTFAARASLYAARQKAK
MLBr_01985|M.leprae_Br4923          KDAGLMTYGEAVEEMLQFGESEGELIGMSPEEWRRFVGRASLYAAREKAK
MAV_2781|M.avium_104                DDAGLMTYGEAVAEVLEFAASEGEPADMSADEWRAFAARASLYSAKAKAK
TH_0417|M.thermoresistible__bu      EDAGLKTYGEAIADRMEFAEADGEPFDMTAEEWRRFAERKSFFEMSQKAA
MAB_4095c|M.abscessus_ATCC_199      --------------------------------------------------
                                                                                      

Mflv_3260|M.gilvum_PYR-GCK          ELGADVAWDCERVKTPEGYYQVRGGIPYAIAKSLAAAPFADILWMETKTA
Mvan_2977|M.vanbaalenii_PYR-1       ELGADVAWDCERVKTPEGYYQVRGGIPYAIAKSLAAAPFADILWMETKTA
MSMEG_3706|M.smegmatis_MC2_155      ELGVDVAWDCEPAKTPEGYYQVRGGIPYAIAKSLAAAPFADILWMETKTA
Rv1916|M.tuberculosis_H37Rv         ELGADPPWDCELAKTPEGYYQIRGGIPYAIAKSLAAAPFADILWMETKTA
Mb1950|M.bovis_AF2122/97            ELGADPPWDCELAKTPEGYYQIRGGIPYAIAKSLAAAPFADILWMETKTA
MMAR_2821|M.marinum_M               ELGVDPGWDCELAKTPEGYYQIRGGIPYAIAKSLAAAPFADILWMETKTA
MUL_2943|M.ulcerans_Agy99           EMGVDPGWDCELAKTPEGYYQIRGGIPYAIAKSLAAAPFADILWMETKTA
MLBr_01985|M.leprae_Br4923          ELGVDPGWDCELAKTPEGYYQIRGGIQYAIAKSLAAAPFADILWMETKTA
MAV_2781|M.avium_104                ELGFDPGWDCELAKTPEGYYQIRGGIPYAIAKSLAAAPFADILWMETKTA
TH_0417|M.thermoresistible__bu      ELGIDVPWDCELAKTPEGYYQLRGGIPYAIAKSLAAAPFADLLWMETKTA
MAB_4095c|M.abscessus_ATCC_199      ------------ERTSEGFYNVQKGIEPCIARAKAYAPYADLIWMETGVP
                                                 :*.**:*::: **  .**:: * **:**::**** ..

Mflv_3260|M.gilvum_PYR-GCK          DLADAKQFADAIHAVYPDKMLAYNLSPSFNWDTTGMTDEEMRAFPEEIGK
Mvan_2977|M.vanbaalenii_PYR-1       DLADAKQFADAIHAVYPDKMLAYNLSPSFNWDTTGMSDEEMRTFPEEIGK
MSMEG_3706|M.smegmatis_MC2_155      DLADAKQFADAIHAVYPDQMLAYNLSPSFNWDTTGMTDDEMRAFPEELGK
Rv1916|M.tuberculosis_H37Rv         DLADARQFAEAIHAEFPDQMLAYNLSPSFNWDTTGMTDEEMRRFPEELGK
Mb1950|M.bovis_AF2122/97            DLADARQFAEAIHAEFPDQMLAYNLSPSFNWDTTGMTDEEMRRFPEELGK
MMAR_2821|M.marinum_M               DLADARQFAEAIHAEFPDQMLAYNLSPSFNWDTTGMTDEEMKRFPEELGK
MUL_2943|M.ulcerans_Agy99           DLADARQFAEAIHAEFPDQMLAYNLSPSFNWDTTGMTDEEMKRFPEELGK
MLBr_01985|M.leprae_Br4923          DLADARQFAEAIHAEFPEQMLAYNLSPSFNWDTTGMSDEEMKRFPEELGK
MAV_2781|M.avium_104                DLADAKQFADAIHAEFPDQMLAYNLSPSFNWDTTGMTDEQMKQFPEELGK
TH_0417|M.thermoresistible__bu      DLDDARQFAEAIHAQFPDKMLAYNLSPSFNWDTTGMTDEEMRAFPAELGK
MAB_4095c|M.abscessus_ATCC_199      DLEVARKFAEAVKADFPDQLLSYNCSPSFNWKQH-LDDSTIAKFQKELGA
                                    **  *::**:*::* :*:::*:** ******.   : *. :  *  *:* 

Mflv_3260|M.gilvum_PYR-GCK          MGFVFNFITYGGHQVDGVASEEFATSLRQEGMLALARLQRKMRLVESPYR
Mvan_2977|M.vanbaalenii_PYR-1       MGFVFNFITYGGHQVDGVASEEFATSLRQEGMLALARLQRKMRLVESPYR
MSMEG_3706|M.smegmatis_MC2_155      MGFVFNFITYGGHQVDGVACEEFATSLRQEGMLALARLQRKMRLVESPYR
Rv1916|M.tuberculosis_H37Rv         MGFVFNFITYGGHQIDGVAAEEFATALRQDGMLALARLQRKMRLVESPYR
Mb1950|M.bovis_AF2122/97            MGFVFNFITYGGHQIDGVAAEEFATALRQDGMLALARLQRKMRLVESPYR
MMAR_2821|M.marinum_M               MGFVFNFITYGGHQIDGVASEEFATALRQDGMLALARLQRKMRLVESPYR
MUL_2943|M.ulcerans_Agy99           MGFVFNFITYGGHQIDGVASEEFATALRQDGMLALARLQRKMRLVESPYR
MLBr_01985|M.leprae_Br4923          MGFVFNFITYGGHQIDGVAAEEFATALRQDGMLALARLQRKMRLVESPYR
MAV_2781|M.avium_104                MGFVFNFITYGGHQIDGVAAEEFATSLQQDGMLALARLQRKMRLVESPYR
TH_0417|M.thermoresistible__bu      MGFVFNFITYGGHQIDGVAAEEFATALRQDGMLALARIQRKLRLIESPYR
MAB_4095c|M.abscessus_ATCC_199      MGFKFQFITLAGFHALNYSMFDLAYGYAREGMTAYVDLQ-----------
                                    *** *:*** .*.:  . :  ::* .  ::** * . :*           

Mflv_3260|M.gilvum_PYR-GCK          TPQTLVGGPRSDAALAASSGRTATTKSMGKGSTQHQHLLQTEVPKKLLEE
Mvan_2977|M.vanbaalenii_PYR-1       TPQTLVGGPRSDAALAASSGRTATTKSMGKGSTQHQHLVQTEVPKKLLEE
MSMEG_3706|M.smegmatis_MC2_155      TPQTLVGGPRSDAALAASSGRTATTKAMGKGSTQHQHLVQTEVPKKLLEE
Rv1916|M.tuberculosis_H37Rv         TPQTLVGGPRSDAALAASSGRTATTKAMGKGSTQHQHLVQTEVPRKLLEE
Mb1950|M.bovis_AF2122/97            TPQTLVGGPRSDAALAASSGRTATTKAMGKGSTQHQHLVQTEVPRKLLEE
MMAR_2821|M.marinum_M               TPQTLVGGPRSDAALQASSGRTATTKAMGKGSTQHQHLVQTEVPKKLLEE
MUL_2943|M.ulcerans_Agy99           TPQTLVAGPRSDAALQASSGRTATTKAMGKGSTQHQHLVQTEVPKKLLEE
MLBr_01985|M.leprae_Br4923          TPQTLVGGPRSDAALAASSGRTATTKAMGKGSTQHQHLVQTEVPKKLLEE
MAV_2781|M.avium_104                TPQTLVGGPRSDAALAASSGRTATTKAMGEGSTQHQHLVQTEVPKKLLEE
TH_0417|M.thermoresistible__bu      TPQTLVGGPRSDAALTASSGRTATTKAMGEGSTQHQHLVQTEVPKKLLEE
MAB_4095c|M.abscessus_ATCC_199      -------------------EREFASEARGYTATKHQREVG----------
                                                        *  :::: *  :*:**: :           

Mflv_3260|M.gilvum_PYR-GCK          WLALWSEHNKLPERLHVQLRPRRAGSDVLDLQILG----DSEDPLANVVV
Mvan_2977|M.vanbaalenii_PYR-1       WLGLWSEHYQLPERLHVQLRPRRAGSDVLDLQILG----DSEEPLANVVV
MSMEG_3706|M.smegmatis_MC2_155      WLAMWSEHYGLPEKLHVQLRPRRAGSDVLDLQILGEG-GDGTDPLANVVV
Rv1916|M.tuberculosis_H37Rv         WLAMWSGHYQLKDKLRVQLRPQRAGSEVLELGIHGE----SDDKLANVIF
Mb1950|M.bovis_AF2122/97            WLAMWSGHYQLKDKLRVQLRPQRAGSEVLELGIHGE----SDDKLANVIF
MMAR_2821|M.marinum_M               WLALWSDHYQLGEKLRVQLRPRRAGSDVLELGIYGN----DDEQLANVVF
MUL_2943|M.ulcerans_Agy99           RLALWSDHYQLGEKLRVQLRPRRAGSDVLELGIYGN----DDEQLANVVF
MLBr_01985|M.leprae_Br4923          WLALWSEHYQLGEKLRVQLRPRRAGSDVLELGIYGN----GDEQLANVIV
MAV_2781|M.avium_104                WLAMWSENYHLGEKLRVQLRPRRAGSDVLELGIYGD----GDEQLANVVV
TH_0417|M.thermoresistible__bu      WLGMWSEHYQLGEKLRVQLRPRRAGGEVLELGIFAERPGGEDEKVANVLV
MAB_4095c|M.abscessus_ATCC_199      --------------------------------------------------
                                                                                      

Mflv_3260|M.gilvum_PYR-GCK          DPIKDRHGRSILTVRDQNTFAEHLRQKRLMDVIHLWLIHRFKAEIVYYVT
Mvan_2977|M.vanbaalenii_PYR-1       DPIKDRHGRSILTVRDQNTFAEQMRQKRLMDLIHLWLIHRFKAEIVYYVT
MSMEG_3706|M.smegmatis_MC2_155      DPIKDRHGRSILTVRDQNTFAEQMRKKRLMDLIHLWLIHRFKAEIVYYVT
Rv1916|M.tuberculosis_H37Rv         QPIQDRRGRTILLVRDQNTFGAELRQKRLMTLIHLWLVHRFKAQAVHYVT
Mb1950|M.bovis_AF2122/97            QPIQDRRGRTILLVRDQNTFGAELRQKRLMTLIHLWLVHRFKAQAVHYVT
MMAR_2821|M.marinum_M               DPIKDRHGRSILTVRDQNTFAHKLRQKRLMTLIHLWLVHRFKADAVYYVT
MUL_2943|M.ulcerans_Agy99           DPIKDRHGRSILTVRDQNTFAHKLRQKRLMTLIHLWLVHRFKADAVYYVT
MLBr_01985|M.leprae_Br4923          DPIKDRRGRSILQVRDQNTFAEKLRQKRLMTLIHFWLVHRFKADTVIYVT
MAV_2781|M.avium_104                DPIKDRHGRSILQVRDQNTFAEKLRQKRLMTLIHLWLVHRFKADAVIYVT
TH_0417|M.thermoresistible__bu      DPIRDRHGRSILTVRDQNTFAEALRKKRLMTLIHLWLVHRFKAEAVYYVS
MAB_4095c|M.abscessus_ATCC_199      ----AGYFDKIATTVDPNTSTAALKG------------------------
                                             .*  . * **    ::                         

Mflv_3260|M.gilvum_PYR-GCK          PTEDNIYQTEKMKSHGIFSDVYQEVGEIIVADVNQARIDELLAPDREALT
Mvan_2977|M.vanbaalenii_PYR-1       PTEDNIYQTEKMKSHGIFSDVYQEVGEIIVADVNQARIDELLAPDRKALI
MSMEG_3706|M.smegmatis_MC2_155      PTEDNIYQTEKMKAHGIFSDVYQEVGEIIVADVNKPRIEELLASDREALG
Rv1916|M.tuberculosis_H37Rv         PTDDNLYQTSKMKSHGIFTEVNQEVGEIIVAEVNHPRIAELLTPDRVALR
Mb1950|M.bovis_AF2122/97            PTDDNLYQTSKMKSHGIFTEVNQEVGEIIVAEVNHPRIAELLTPDRVALR
MMAR_2821|M.marinum_M               PTEDNQYQTSKMKSHGIFSEVNQDVGEIIVAEVNRPRIEELLTADRVALR
MUL_2943|M.ulcerans_Agy99           PTEDNQYQTSKMKSHGIFSEVNQDVGEIIVAEVNRPRIEELLTADRVALR
MLBr_01985|M.leprae_Br4923          PTEDNLYQTSKMKSHGIFSEVYQEVGEIIVAEVNHPRLVELLTPDRVALR
MAV_2781|M.avium_104                PTEDNLYQTSKMKSHGIFSEVYQEVGEIIVAEVNRPRIAELLQPDRVALR
TH_0417|M.thermoresistible__bu      PTEDNLYQTSKMKSHGIFSEVHQDVGEIIVADVNRERIEELLAPDREALR
MAB_4095c|M.abscessus_ATCC_199      STEEGQFH------------------------------------------
                                    .*::. ::                                          

Mflv_3260|M.gilvum_PYR-GCK          RLITKQD
Mvan_2977|M.vanbaalenii_PYR-1       RLINKQD
MSMEG_3706|M.smegmatis_MC2_155      RLIRKED
Rv1916|M.tuberculosis_H37Rv         KLITKEA
Mb1950|M.bovis_AF2122/97            KLITKEA
MMAR_2821|M.marinum_M               QLITKGD
MUL_2943|M.ulcerans_Agy99           QLITKGD
MLBr_01985|M.leprae_Br4923          RLITKEG
MAV_2781|M.avium_104                KLITKEG
TH_0417|M.thermoresistible__bu      RLIRKED
MAB_4095c|M.abscessus_ATCC_199      -------