For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MAIAETDTEVHTPFEQDFEKDVAATQRYFDSSRFAGIIRLYTARQVVEQRGTIPVDHIVAREAAGAFYER LRELFAARKSITTFGPYSPGQAVSMKRMGIEAIYLGGWATSAKGSSTEDPGPDLASYPLSQVPDDAAVLV RALLTADRNQHYLRLQMSERQRAATPAYDFRPFIIADADTGHGGDPHVRNLIRRFVEVGVPGYHIEDQRP GTKKCGHQGGKVLVPSDEQIKRLNAARFQLDIMRVPGIIVARTDAEAANLIDSRADERDQPFLLGATKLD VPSYKSCFLAMVRRFYELGVKELNGHLLYALGDSEYAAAGGWLERQGIFGLVSDAVNAWREDGQQSIDGI FDQVESRFVAAWEDDAGLMTYGEAVADVLEFGQSEGEPIGMAPEEWRAFAARASLHAARAKAKELGADPP WDCELAKTPEGYYQIRGGIPYAIAKSLAAAPFADILWMETKTADLADARQFAEAIHAEFPDQMLAYNLSP SFNWDTTGMTDEEMRRFPEELGKMGFVFNFITYGGHQIDGVAAEEFATALRQDGMLALARLQRKMRLVES PYRTPQTLVGGPRSDAALAASSGRTATTKAMGKGSTQHQHLVQTEVPRKLLEEWLAMWSGHYQLKDKLRV QLRPQRAGSEVLELGIHGESDDKLANVIFQPIQDRRGRTILLVRDQNTFGAELRQKRLMTLIHLWLVHRF KAQAVHYVTPTDDNLYQTSKMKSHGIFTEVNQEVGEIIVAEVNHPRIAELLTPDRVALRKLITKEA
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb1950 | aceA | - | 100% (766) | isocitrate lyase |
M. bovis AF2122 / 97 | Mb0476 | icl | 2e-39 | 35.60% (250) | isocitrate lyase |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. gilvum PYR-GCK | Mflv_3260 | - | 0.0 | 78.82% (765) | isocitrate lyase |
M. tuberculosis H37Rv | Rv1916 | aceAb | 0.0 | 100.00% (398) | isocitrate lyase |
M. leprae Br4923 | MLBr_01985 | aceA | 0.0 | 86.27% (765) | isocitrate lyase |
M. abscessus ATCC 19977 | MAB_4095c | - | 3e-37 | 35.41% (257) | isocitrate lyase (AceA) |
M. marinum M | MMAR_2821 | aceAb | 0.0 | 88.87% (764) | isocitrate lyase AceAb |
M. avium 104 | MAV_2781 | aceA | 0.0 | 86.27% (765) | isocitrate lyase |
M. smegmatis MC2 155 | MSMEG_3706 | aceA | 0.0 | 77.21% (768) | isocitrate lyase |
M. thermoresistible (build 8) | TH_0417 | aceAb | 0.0 | 79.32% (769) | PROBABLE ISOCITRATE LYASE aceAb |
M. ulcerans Agy99 | MUL_2943 | aceAb | 0.0 | 88.09% (764) | isocitrate lyase AceAb |
M. vanbaalenii PYR-1 | Mvan_2977 | - | 0.0 | 78.69% (765) | isocitrate lyase |
CLUSTAL 2.0.9 multiple sequence alignment Mflv_3260|M.gilvum_PYR-GCK ------------------------------------MAITEADLQS---- Mvan_2977|M.vanbaalenii_PYR-1 ------------------------------------MAIIEADAFQPHAT MSMEG_3706|M.smegmatis_MC2_155 ------------------------------------MATIEANAHNLSSS Mb1950|M.bovis_AF2122/97 ------------------------------------MAIAETDTEVHTPF Rv1916|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_2821|M.marinum_M ------------------------------------MAIAETDTEVRTP- MUL_2943|M.ulcerans_Agy99 ------------------------------------MAIVETDTEIRTP- MLBr_01985|M.leprae_Br4923 MAGIPATVVQRCNSTNLDDRLHYSPLGDRAKEERNPMAIMDTNTEVHTL- MAV_2781|M.avium_104 ------------------------------------MAIIDKETQVRPS- TH_0417|M.thermoresistible__bu ------------------------------------MAISEAERETRTS- MAB_4095c|M.abscessus_ATCC_199 ------------------------------------MSNVGK-------- Mflv_3260|M.gilvum_PYR-GCK QTPFERDVVETQRYFDS-PRFEGIIRLYTARQVAEQRGTIPADYPVAREA Mvan_2977|M.vanbaalenii_PYR-1 GEPFERDVAETQRYFDS-PRFDGITRLYTARQVAEQRGTIPADYPTAREA MSMEG_3706|M.smegmatis_MC2_155 AKDFDSEVAATQAYFDS-PRFEGITRLYSARQVVEQRGTIATDHTVAREA Mb1950|M.bovis_AF2122/97 EQDFEKDVAATQRYFDS-SRFAGIIRLYTARQVVEQRGTIPVDHIVAREA Rv1916|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_2821|M.marinum_M ---FEQEVADTQRYFDS-SRFAGIVRLYTARQVVEQRGTIPNDYTVARTA MUL_2943|M.ulcerans_Agy99 ---FEQEVADTQRYFDS-SRFAGIVRLYTARQVVEQRGTIPNDYTVARTA MLBr_01985|M.leprae_Br4923 ---FTQEVAATQQYFDD-PRFAGIIRLYTARQVVEQRGTIPTDYTVARDA MAV_2781|M.avium_104 ---FDDEVAATQRYFDD-PRFARITRLYTARQVAEQRGTIRTDYTVARDA TH_0417|M.thermoresistible__bu ---FEEDVAETQRYFDS-PRFDGIIRLYTARQVVEQRGTIPVDYTIAREA MAB_4095c|M.abscessus_ATCC_199 ----PRTAAEIQQDWDTNPRWKGITRDYTAAQVEELQGSVVEENTLARRG Mflv_3260|M.gilvum_PYR-GCK ATAFFPHLRELFGQGRSITTFGPYSPGQAVVMKRMGIEGIYLGGWATSAK Mvan_2977|M.vanbaalenii_PYR-1 ATAFYPHLRELFAKGKSITTFGPYSPGQAVVMKRMGIEGVYLGGWATSAK MSMEG_3706|M.smegmatis_MC2_155 AEAFHPYLRELFAQKKSITTFGPYSPGQAVVMKRMGIGGIYLGGWATSAK Mb1950|M.bovis_AF2122/97 AGAFYERLRELFAARKSITTFGPYSPGQAVSMKRMGIEAIYLGGWATSAK Rv1916|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_2821|M.marinum_M AGAFYQRLRELYAEKKSVTTFGPYSPGQAVSMKRMGIEAIYLGGWATSAK MUL_2943|M.ulcerans_Agy99 AGVFYQRLRELYAEKKSVTTFGPYSPGQAVSMKRMGIEAIYLGGWATSAK MLBr_01985|M.leprae_Br4923 ATAFYARLRELFAAGKSVTTFGPYSPGQAVSLKRMGIEAIYLGGWATSAK MAV_2781|M.avium_104 AAAFYERLRELFAQKKSITTFGPYSPGQAVTMKRMGIEGIYLGGWATSAK TH_0417|M.thermoresistible__bu ATAFYARLRELFAERKCITTFGPYSPGQAVTMKRMGIEGIYLGGWATSAK MAB_4095c|M.abscessus_ATCC_199 AEILWDAVSK--DDDSYINALGALTGNMAVQQVRAGLKAIYLSGWQVAGD Mflv_3260|M.gilvum_PYR-GCK GSISEDPGPDLASYPLSQVPEEAAGIVRALLTADRNQQYLRLQMTPEQQA Mvan_2977|M.vanbaalenii_PYR-1 GSISEDPGPDLASYPLSQVPEEAASIVRALLTADRNQHYLRLQMDPEQRA MSMEG_3706|M.smegmatis_MC2_155 GSISEDPGPDLASYPLSQVPDEAAGLVRALLTADRNQHYLRLQMTPEQRE Mb1950|M.bovis_AF2122/97 GSSTEDPGPDLASYPLSQVPDDAAVLVRALLTADRNQHYLRLQMSERQRA Rv1916|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_2821|M.marinum_M GSTTEDPGPDLASYPLSQVPDDAAVLVRALLTADRNQEYLRLQMTDQQRA MUL_2943|M.ulcerans_Agy99 GSTTEDPGPDLASYPLSQVPDDAAVLVRALLTADRNQEYLRLQMTDQQRA MLBr_01985|M.leprae_Br4923 GSITEDPGPDLASYPLSQVPDDAAVLVRALLAADRNQQYLRLHMTEQQRA MAV_2781|M.avium_104 GSTTEDPGPDLASYPLSQVPDDAAVLVRALLTADRNQQYLRLQMSEQQRA TH_0417|M.thermoresistible__bu GSADEDPGPDLASYPLSQVPNEAAGLVRALLTADRNQEYLRQRMSPEQRA MAB_4095c|M.abscessus_ATCC_199 ANLSGHTYPDQSLYPANSVPAVVRRINNALLRADEIAR---------VEG Mflv_3260|M.gilvum_PYR-GCK TTPAYDYRPFIIADADTGHGGDPHVRNLIRRFVENGVPGYHIEDQRPGTK Mvan_2977|M.vanbaalenii_PYR-1 AAPEYDYRPFIIADADTGHGGDPHVRNLIRRFVEAGVPGYHIEDQRPGTK MSMEG_3706|M.smegmatis_MC2_155 AQPPVDYRPFIIADADTGHGGDPHVRNLIRRFVESGVPGYHIEDQRPGTK Mb1950|M.bovis_AF2122/97 ATPAYDFRPFIIADADTGHGGDPHVRNLIRRFVEVGVPGYHIEDQRPGTK Rv1916|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_2821|M.marinum_M TTTAYDFRPFIIADADTGHGGDPHVRNLIRRFVEVGVPGYHIEDQRPGTK MUL_2943|M.ulcerans_Agy99 TTTAYDFRPFIIADADTGHGGDPHVRNLIRRFVEVGVPGYHIEDQRPGTK MLBr_01985|M.leprae_Br4923 ATPAYDYRPFIIADADTGHGGDSHVRNLIRRFVEIGVPGYHIEDQRPGTK MAV_2781|M.avium_104 ATKEYDYRPFIIADADTGHGGDPHVRNLIRRFVEVGVPGYHIEDQRPGTK TH_0417|M.thermoresistible__bu ATPVYDYRPFIIADADTGHGGDAHVRNLIRRFVEAGVAGYHIEDQRPGTK MAB_4095c|M.abscessus_ATCC_199 DTSVDNWLVPIVADGEAGFGGALNVYELQKAMIAAGAAGTHWEDQLASEK Mflv_3260|M.gilvum_PYR-GCK KCGHQGGKVLVPSDEQIKRLNTARFQLDIMRVPGIIVARTDAEAANLIDS Mvan_2977|M.vanbaalenii_PYR-1 KCGHQGGKVLVPSDEQIKRLNTARFQLDIMRVPGIIVARTDAEAANLIDS MSMEG_3706|M.smegmatis_MC2_155 KCGHQGGKVLVPSDEQIKRLNTARFQLDIMRVPGIIVARTDAEAANLIDS Mb1950|M.bovis_AF2122/97 KCGHQGGKVLVPSDEQIKRLNAARFQLDIMRVPGIIVARTDAEAANLIDS Rv1916|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_2821|M.marinum_M KCGHQGGKVLVPSDEQIKRLNAARFQLDVMRVPGIIVARTDAEAANLIDS MUL_2943|M.ulcerans_Agy99 KCGHQGGKVLVPSDEQIKRLNAARFQLDVMRVPGIIVARTDAEAANLIDS MLBr_01985|M.leprae_Br4923 KCGHQGGKVLVPSDEQIKRLNAARFQLDIMRVPGIIVARTDAEAANLIDS MAV_2781|M.avium_104 KCGHQGGKVLVPSDEQIKRLNAARFQLDIMRVPGIIVARTDAEAANLLDS TH_0417|M.thermoresistible__bu KCGHQGGKVLVPSDEQIKRLNTARFQLDIMRVPGIIVARTDAEAANLIDS MAB_4095c|M.abscessus_ATCC_199 KCGHLGGKVLIPTQQHIRTLTSARLAADVANTPTVVIARTDAEAATLITS Mflv_3260|M.gilvum_PYR-GCK RADERDQPFLLGATNLKIPSYKSCYLAMMRRFYDKGVTELNGHLLYALPD Mvan_2977|M.vanbaalenii_PYR-1 RADERDQPFLLGATNLKIPSYKSCFLAMVRRFYEKGMTELNGHLLYALPE MSMEG_3706|M.smegmatis_MC2_155 RADERDQPFLLGVTNLKIPSYKSCFLAMMRRFYDQGLTEINGHLLYDLPE Mb1950|M.bovis_AF2122/97 RADERDQPFLLGATKLDVPSYKSCFLAMVRRFYELGVKELNGHLLYALGD Rv1916|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_2821|M.marinum_M RADERDQPFLLGATKLDIPSYKSCFLAMLRRFYELGVKELNGHLLYALAD MUL_2943|M.ulcerans_Agy99 RADERDQPFLLGATKLDIPSYKSCFLAMLRRFYELGVKELNGHLLYALAD MLBr_01985|M.leprae_Br4923 RADERDQPFLLGATNLKIPSYKACFLALVRCFYELGVKELHGHLLYALGD MAV_2781|M.avium_104 RADERDQPFLLGATNLDIPSYKACFLAMVRRFYELGVKDLNGHLLYALPE TH_0417|M.thermoresistible__bu RADERDQPFLLGATNLAIPSYKSCYLAMLRSFYDSGVTELNGHLLYWLAE MAB_4095c|M.abscessus_ATCC_199 DVDERDKPFVTG-------------------------------------- Mflv_3260|M.gilvum_PYR-GCK GEYATAEAWLQRQGVLDLVDQTAAAWQDGTEASLDTAFDKVESRFVEAWQ Mvan_2977|M.vanbaalenii_PYR-1 GEYATATAWLDRQGVLNLIDETASAWQAGTESSVDAAFDRVESRFVDAWQ MSMEG_3706|M.smegmatis_MC2_155 GQYEAAEAWLTGAGIMDEIAAAVESWTSGAASSVDALYDAVESKFVDAWQ Mb1950|M.bovis_AF2122/97 SEYAAAGGWLERQGIFGLVSDAVNAWREDGQQSIDGIFDQVESRFVAAWE Rv1916|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_2821|M.marinum_M AEYAAANGWLERSGIMSLISDAVNSWREDGMQTIDDLFDQVESRFVAAWE MUL_2943|M.ulcerans_Agy99 AEYAAANGWLERSGIMGLISDAVNSWREDGMQTTDDLFDQVESRFVAAWE MLBr_01985|M.leprae_Br4923 GEYAAASAWLDRQGILAQVSGTVNAWQENGKQSIDDLFEQVEYRLLAAWE MAV_2781|M.avium_104 AEYAEATAWLERQGIQGVISDAVNTWRENGQQSIDDLFDQVESRFVAAWE TH_0417|M.thermoresistible__bu GEYDRARAWLDRNGLLDRISEAVGKWRPGEDPANDELFDEVESAFVEIWE MAB_4095c|M.abscessus_ATCC_199 -------------------------------------------------- Mflv_3260|M.gilvum_PYR-GCK DDAGLNTYGEAVAELLEFREREGEPSPMSVAQWREFAERAPLYTAREKAK Mvan_2977|M.vanbaalenii_PYR-1 DDAGLNTYGEAVAELLEFREREGEPSSMSVADWRMFAERAPLYTAREKAK MSMEG_3706|M.smegmatis_MC2_155 DDAGLNTYGEAVAEVIEFREREGESVAMSAAEWREFATRAPLYTATNKAR Mb1950|M.bovis_AF2122/97 DDAGLMTYGEAVADVLEFGQSEGEPIGMAPEEWRAFAARASLHAARAKAK Rv1916|M.tuberculosis_H37Rv -----MTYGEAVADVLEFGQSEGEPIGMAPEEWRAFAARASLHAARAKAK MMAR_2821|M.marinum_M DDAGLMTYAEAVAEVLAFGQSEGDPVAMSPEEWRTFAARASLYAARQKAK MUL_2943|M.ulcerans_Agy99 DDAGLMTYAEAVAEVLAFGQSEGDPVPMSPEEWRTFAARASLYAARQKAK MLBr_01985|M.leprae_Br4923 KDAGLMTYGEAVEEMLQFGESEGELIGMSPEEWRRFVGRASLYAAREKAK MAV_2781|M.avium_104 DDAGLMTYGEAVAEVLEFAASEGEPADMSADEWRAFAARASLYSAKAKAK TH_0417|M.thermoresistible__bu EDAGLKTYGEAIADRMEFAEADGEPFDMTAEEWRRFAERKSFFEMSQKAA MAB_4095c|M.abscessus_ATCC_199 -------------------------------------------------- Mflv_3260|M.gilvum_PYR-GCK ELGADVAWDCERVKTPEGYYQVRGGIPYAIAKSLAAAPFADILWMETKTA Mvan_2977|M.vanbaalenii_PYR-1 ELGADVAWDCERVKTPEGYYQVRGGIPYAIAKSLAAAPFADILWMETKTA MSMEG_3706|M.smegmatis_MC2_155 ELGVDVAWDCEPAKTPEGYYQVRGGIPYAIAKSLAAAPFADILWMETKTA Mb1950|M.bovis_AF2122/97 ELGADPPWDCELAKTPEGYYQIRGGIPYAIAKSLAAAPFADILWMETKTA Rv1916|M.tuberculosis_H37Rv ELGADPPWDCELAKTPEGYYQIRGGIPYAIAKSLAAAPFADILWMETKTA MMAR_2821|M.marinum_M ELGVDPGWDCELAKTPEGYYQIRGGIPYAIAKSLAAAPFADILWMETKTA MUL_2943|M.ulcerans_Agy99 EMGVDPGWDCELAKTPEGYYQIRGGIPYAIAKSLAAAPFADILWMETKTA MLBr_01985|M.leprae_Br4923 ELGVDPGWDCELAKTPEGYYQIRGGIQYAIAKSLAAAPFADILWMETKTA MAV_2781|M.avium_104 ELGFDPGWDCELAKTPEGYYQIRGGIPYAIAKSLAAAPFADILWMETKTA TH_0417|M.thermoresistible__bu ELGIDVPWDCELAKTPEGYYQLRGGIPYAIAKSLAAAPFADLLWMETKTA MAB_4095c|M.abscessus_ATCC_199 ------------ERTSEGFYNVQKGIEPCIARAKAYAPYADLIWMETGVP :*.**:*::: ** .**:: * **:**::**** .. Mflv_3260|M.gilvum_PYR-GCK DLADAKQFADAIHAVYPDKMLAYNLSPSFNWDTTGMTDEEMRAFPEEIGK Mvan_2977|M.vanbaalenii_PYR-1 DLADAKQFADAIHAVYPDKMLAYNLSPSFNWDTTGMSDEEMRTFPEEIGK MSMEG_3706|M.smegmatis_MC2_155 DLADAKQFADAIHAVYPDQMLAYNLSPSFNWDTTGMTDDEMRAFPEELGK Mb1950|M.bovis_AF2122/97 DLADARQFAEAIHAEFPDQMLAYNLSPSFNWDTTGMTDEEMRRFPEELGK Rv1916|M.tuberculosis_H37Rv DLADARQFAEAIHAEFPDQMLAYNLSPSFNWDTTGMTDEEMRRFPEELGK MMAR_2821|M.marinum_M DLADARQFAEAIHAEFPDQMLAYNLSPSFNWDTTGMTDEEMKRFPEELGK MUL_2943|M.ulcerans_Agy99 DLADARQFAEAIHAEFPDQMLAYNLSPSFNWDTTGMTDEEMKRFPEELGK MLBr_01985|M.leprae_Br4923 DLADARQFAEAIHAEFPEQMLAYNLSPSFNWDTTGMSDEEMKRFPEELGK MAV_2781|M.avium_104 DLADAKQFADAIHAEFPDQMLAYNLSPSFNWDTTGMTDEQMKQFPEELGK TH_0417|M.thermoresistible__bu DLDDARQFAEAIHAQFPDKMLAYNLSPSFNWDTTGMTDEEMRAFPAELGK MAB_4095c|M.abscessus_ATCC_199 DLEVARKFAEAVKADFPDQLLSYNCSPSFNWKQH-LDDSTIAKFQKELGA ** *::**:*::* :*:::*:** ******. : *. : * *:* Mflv_3260|M.gilvum_PYR-GCK MGFVFNFITYGGHQVDGVASEEFATSLRQEGMLALARLQRKMRLVESPYR Mvan_2977|M.vanbaalenii_PYR-1 MGFVFNFITYGGHQVDGVASEEFATSLRQEGMLALARLQRKMRLVESPYR MSMEG_3706|M.smegmatis_MC2_155 MGFVFNFITYGGHQVDGVACEEFATSLRQEGMLALARLQRKMRLVESPYR Mb1950|M.bovis_AF2122/97 MGFVFNFITYGGHQIDGVAAEEFATALRQDGMLALARLQRKMRLVESPYR Rv1916|M.tuberculosis_H37Rv MGFVFNFITYGGHQIDGVAAEEFATALRQDGMLALARLQRKMRLVESPYR MMAR_2821|M.marinum_M MGFVFNFITYGGHQIDGVASEEFATALRQDGMLALARLQRKMRLVESPYR MUL_2943|M.ulcerans_Agy99 MGFVFNFITYGGHQIDGVASEEFATALRQDGMLALARLQRKMRLVESPYR MLBr_01985|M.leprae_Br4923 MGFVFNFITYGGHQIDGVAAEEFATALRQDGMLALARLQRKMRLVESPYR MAV_2781|M.avium_104 MGFVFNFITYGGHQIDGVAAEEFATSLQQDGMLALARLQRKMRLVESPYR TH_0417|M.thermoresistible__bu MGFVFNFITYGGHQIDGVAAEEFATALRQDGMLALARIQRKLRLIESPYR MAB_4095c|M.abscessus_ATCC_199 MGFKFQFITLAGFHALNYSMFDLAYGYAREGMTAYVDLQ----------- *** *:*** .*.: . : ::* . ::** * . :* Mflv_3260|M.gilvum_PYR-GCK TPQTLVGGPRSDAALAASSGRTATTKSMGKGSTQHQHLLQTEVPKKLLEE Mvan_2977|M.vanbaalenii_PYR-1 TPQTLVGGPRSDAALAASSGRTATTKSMGKGSTQHQHLVQTEVPKKLLEE MSMEG_3706|M.smegmatis_MC2_155 TPQTLVGGPRSDAALAASSGRTATTKAMGKGSTQHQHLVQTEVPKKLLEE Mb1950|M.bovis_AF2122/97 TPQTLVGGPRSDAALAASSGRTATTKAMGKGSTQHQHLVQTEVPRKLLEE Rv1916|M.tuberculosis_H37Rv TPQTLVGGPRSDAALAASSGRTATTKAMGKGSTQHQHLVQTEVPRKLLEE MMAR_2821|M.marinum_M TPQTLVGGPRSDAALQASSGRTATTKAMGKGSTQHQHLVQTEVPKKLLEE MUL_2943|M.ulcerans_Agy99 TPQTLVAGPRSDAALQASSGRTATTKAMGKGSTQHQHLVQTEVPKKLLEE MLBr_01985|M.leprae_Br4923 TPQTLVGGPRSDAALAASSGRTATTKAMGKGSTQHQHLVQTEVPKKLLEE MAV_2781|M.avium_104 TPQTLVGGPRSDAALAASSGRTATTKAMGEGSTQHQHLVQTEVPKKLLEE TH_0417|M.thermoresistible__bu TPQTLVGGPRSDAALTASSGRTATTKAMGEGSTQHQHLVQTEVPKKLLEE MAB_4095c|M.abscessus_ATCC_199 -------------------EREFASEARGYTATKHQREVG---------- * :::: * :*:**: : Mflv_3260|M.gilvum_PYR-GCK WLALWSEHNKLPERLHVQLRPRRAGSDVLDLQILG----DSEDPLANVVV Mvan_2977|M.vanbaalenii_PYR-1 WLGLWSEHYQLPERLHVQLRPRRAGSDVLDLQILG----DSEEPLANVVV MSMEG_3706|M.smegmatis_MC2_155 WLAMWSEHYGLPEKLHVQLRPRRAGSDVLDLQILGEG-GDGTDPLANVVV Mb1950|M.bovis_AF2122/97 WLAMWSGHYQLKDKLRVQLRPQRAGSEVLELGIHGE----SDDKLANVIF Rv1916|M.tuberculosis_H37Rv WLAMWSGHYQLKDKLRVQLRPQRAGSEVLELGIHGE----SDDKLANVIF MMAR_2821|M.marinum_M WLALWSDHYQLGEKLRVQLRPRRAGSDVLELGIYGN----DDEQLANVVF MUL_2943|M.ulcerans_Agy99 RLALWSDHYQLGEKLRVQLRPRRAGSDVLELGIYGN----DDEQLANVVF MLBr_01985|M.leprae_Br4923 WLALWSEHYQLGEKLRVQLRPRRAGSDVLELGIYGN----GDEQLANVIV MAV_2781|M.avium_104 WLAMWSENYHLGEKLRVQLRPRRAGSDVLELGIYGD----GDEQLANVVV TH_0417|M.thermoresistible__bu WLGMWSEHYQLGEKLRVQLRPRRAGGEVLELGIFAERPGGEDEKVANVLV MAB_4095c|M.abscessus_ATCC_199 -------------------------------------------------- Mflv_3260|M.gilvum_PYR-GCK DPIKDRHGRSILTVRDQNTFAEHLRQKRLMDVIHLWLIHRFKAEIVYYVT Mvan_2977|M.vanbaalenii_PYR-1 DPIKDRHGRSILTVRDQNTFAEQMRQKRLMDLIHLWLIHRFKAEIVYYVT MSMEG_3706|M.smegmatis_MC2_155 DPIKDRHGRSILTVRDQNTFAEQMRKKRLMDLIHLWLIHRFKAEIVYYVT Mb1950|M.bovis_AF2122/97 QPIQDRRGRTILLVRDQNTFGAELRQKRLMTLIHLWLVHRFKAQAVHYVT Rv1916|M.tuberculosis_H37Rv QPIQDRRGRTILLVRDQNTFGAELRQKRLMTLIHLWLVHRFKAQAVHYVT MMAR_2821|M.marinum_M DPIKDRHGRSILTVRDQNTFAHKLRQKRLMTLIHLWLVHRFKADAVYYVT MUL_2943|M.ulcerans_Agy99 DPIKDRHGRSILTVRDQNTFAHKLRQKRLMTLIHLWLVHRFKADAVYYVT MLBr_01985|M.leprae_Br4923 DPIKDRRGRSILQVRDQNTFAEKLRQKRLMTLIHFWLVHRFKADTVIYVT MAV_2781|M.avium_104 DPIKDRHGRSILQVRDQNTFAEKLRQKRLMTLIHLWLVHRFKADAVIYVT TH_0417|M.thermoresistible__bu DPIRDRHGRSILTVRDQNTFAEALRKKRLMTLIHLWLVHRFKAEAVYYVS MAB_4095c|M.abscessus_ATCC_199 ----AGYFDKIATTVDPNTSTAALKG------------------------ .* . * ** :: Mflv_3260|M.gilvum_PYR-GCK PTEDNIYQTEKMKSHGIFSDVYQEVGEIIVADVNQARIDELLAPDREALT Mvan_2977|M.vanbaalenii_PYR-1 PTEDNIYQTEKMKSHGIFSDVYQEVGEIIVADVNQARIDELLAPDRKALI MSMEG_3706|M.smegmatis_MC2_155 PTEDNIYQTEKMKAHGIFSDVYQEVGEIIVADVNKPRIEELLASDREALG Mb1950|M.bovis_AF2122/97 PTDDNLYQTSKMKSHGIFTEVNQEVGEIIVAEVNHPRIAELLTPDRVALR Rv1916|M.tuberculosis_H37Rv PTDDNLYQTSKMKSHGIFTEVNQEVGEIIVAEVNHPRIAELLTPDRVALR MMAR_2821|M.marinum_M PTEDNQYQTSKMKSHGIFSEVNQDVGEIIVAEVNRPRIEELLTADRVALR MUL_2943|M.ulcerans_Agy99 PTEDNQYQTSKMKSHGIFSEVNQDVGEIIVAEVNRPRIEELLTADRVALR MLBr_01985|M.leprae_Br4923 PTEDNLYQTSKMKSHGIFSEVYQEVGEIIVAEVNHPRLVELLTPDRVALR MAV_2781|M.avium_104 PTEDNLYQTSKMKSHGIFSEVYQEVGEIIVAEVNRPRIAELLQPDRVALR TH_0417|M.thermoresistible__bu PTEDNLYQTSKMKSHGIFSEVHQDVGEIIVADVNRERIEELLAPDREALR MAB_4095c|M.abscessus_ATCC_199 STEEGQFH------------------------------------------ .*::. :: Mflv_3260|M.gilvum_PYR-GCK RLITKQD Mvan_2977|M.vanbaalenii_PYR-1 RLINKQD MSMEG_3706|M.smegmatis_MC2_155 RLIRKED Mb1950|M.bovis_AF2122/97 KLITKEA Rv1916|M.tuberculosis_H37Rv KLITKEA MMAR_2821|M.marinum_M QLITKGD MUL_2943|M.ulcerans_Agy99 QLITKGD MLBr_01985|M.leprae_Br4923 RLITKEG MAV_2781|M.avium_104 KLITKEG TH_0417|M.thermoresistible__bu RLIRKED MAB_4095c|M.abscessus_ATCC_199 -------