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VAESDRLLGGYDPNAGYSAHAGAQPQRIPVPSLLRALLSEHLDAGYAAVAAERERAAAPRCWQARAVSWM WQALAATLVAAVFAAAVAQARSVAPGVRAAQQLLVASVRSTQAAATTLAQRRSTLSAKVDDVRRIVLADD AEGQRLLARLDVLSLAAASAPVVGPGLTVTVTDPGASPNLSDVSKQRVSGSQQIILDRDLQLVVNSLWES GAEAISIDGVRIGPNVTIRQAGGAILVDNNPTSSPYTILAVGPPHAMQDVFDRSAGLYRLRLLETSYGVG VSVNVGDGLALPAGATRDVKFAKQIGP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv1823 | - | - | 100% (307) | hypothetical protein Rv1823 |
| M. tuberculosis H37Rv | Rv0012 | - | 2e-17 | 29.80% (245) | hypothetical protein Rv0012 |
| M. tuberculosis H37Rv | Rv1825 | - | 2e-13 | 29.69% (192) | hypothetical protein Rv1825 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1854 | - | 1e-169 | 100.00% (307) | hypothetical protein Mb1854 |
| M. gilvum PYR-GCK | Mflv_3406 | - | 4e-99 | 62.33% (300) | hypothetical protein Mflv_3406 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2399 | - | 4e-87 | 54.18% (299) | hypothetical protein MAB_2399 |
| M. marinum M | MMAR_2700 | - | 1e-140 | 82.74% (307) | hypothetical protein MMAR_2700 |
| M. avium 104 | MAV_2892 | - | 1e-128 | 75.57% (307) | hypothetical protein MAV_2892 |
| M. smegmatis MC2 155 | MSMEG_3651 | - | 2e-98 | 61.56% (307) | membrane associated protein |
| M. thermoresistible (build 8) | TH_1122 | - | 3e-58 | 71.61% (155) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_3042 | - | 1e-138 | 82.08% (307) | hypothetical protein MUL_3042 |
| M. vanbaalenii PYR-1 | Mvan_3139 | - | 1e-103 | 65.55% (299) | hypothetical protein Mvan_3139 |
CLUSTAL 2.0.9 multiple sequence alignment
Rv1823|M.tuberculosis_H37Rv ---------------MAESDRLLGGY--------DPNAGYSAHAGAQPQR
Mb1854|M.bovis_AF2122/97 ---------------MAESDRLLGGY--------DPNAGYSAHAGAQPQR
MMAR_2700|M.marinum_M ---------------MAEAGRLLGGY--------DPNAGYSAHA-ARPKR
MUL_3042|M.ulcerans_Agy99 ---------------MAEAGRLLGGY--------DPNAGYSAHA-ARPKR
MAV_2892|M.avium_104 ---------------MADVDRALGGY--------DPNAGHSAHLAARPQR
Mflv_3406|M.gilvum_PYR-GCK ---------------MSS----LGGY--------DASTGPTAHRPDAPTR
Mvan_3139|M.vanbaalenii_PYR-1 ---------------MSS----LGGY--------DLSAGRDAHRADAPTR
MSMEG_3651|M.smegmatis_MC2_155 ---------------MST----LGGYGSFTRPYTDPNAGLNRHEAGAPTR
TH_1122|M.thermoresistible__bu --------------------------------------------------
MAB_2399|M.abscessus_ATCC_1997 MDAQDTSANGKEPQIHGTGPHLMGGF--------EPEEGLGHHSANRPKR
Rv1823|M.tuberculosis_H37Rv IPVPSLLRALLSEHLDAGYAAVAAERERAAAPRCWQARAVSWMWQALAAT
Mb1854|M.bovis_AF2122/97 IPVPSLLRALLSEHLDAGYAAVAAERERAAAPRCWQARAVSWMWQALAAT
MMAR_2700|M.marinum_M NPVPSLLRALLSDHLDPGYAAAAAKRESSGAQRTVRARAFGWLWQALAAT
MUL_3042|M.ulcerans_Agy99 NPVPSLLRALLSDHLDPGYAAAAAKRESSGAQRTVRARAFGWLWQVLAAT
MAV_2892|M.avium_104 IPVPSLLRALLSEHLDPGYAAAAAKRGAVDETRNRRPRVSGWLWQALAAL
Mflv_3406|M.gilvum_PYR-GCK IPVPSLLRSLLTDHLDPGYAAAAQDGKP-------RSAVSSALWQVLAAV
Mvan_3139|M.vanbaalenii_PYR-1 IPVPSLLRSLLTEHLDPGYAAAAQAPRR-------RGRVSEMAWQVVAAV
MSMEG_3651|M.smegmatis_MC2_155 IPVPSLLRSLLSEHLDPGYAAAAEERKAGKPP---RKRVFEWGWEVLAAL
TH_1122|M.thermoresistible__bu --------------------------------------------------
MAB_2399|M.abscessus_ATCC_1997 NPVPSLLRTLLSDHLDAGYLEAAQARKNGAKP---RSRLAEWGWQAIAAI
Rv1823|M.tuberculosis_H37Rv LVAAVFAAAVAQARSVAPGVRAAQQLLVASVRSTQAAATTLAQRRSTLSA
Mb1854|M.bovis_AF2122/97 LVAAVFAAAVAQARSVAPGVRAAQQLLVASVRSTQAAATTLAQRRSTLSA
MMAR_2700|M.marinum_M LVAAVFAAAVAQARLVAPGVHAAQQLLVTSVRSTQAAAAELAQRRSALSA
MUL_3042|M.ulcerans_Agy99 LVAAVFAAAVAQARLVAPGVHAAQQLLVTSVRSTQAAAAELAQRRSALSA
MAV_2892|M.avium_104 LIATVFAAAVAQARSVAPGVRSAQQLLLGNVRATEGSAAKLAQRRNELSA
Mflv_3406|M.gilvum_PYR-GCK TIATVFALAWAQARDTAPGVRETQQVMAGSVRAAEAATEEAAARRTSLTA
Mvan_3139|M.vanbaalenii_PYR-1 LVATVFGLAWTQARDTASGVRESQQVLVGSVRSAEAAADTAAERRDSLTA
MSMEG_3651|M.smegmatis_MC2_155 AIAAVFAIAAAQVQLAAPAAREAQHALAARVRAAETAADQSGAERNALAE
TH_1122|M.thermoresistible__bu --------------------------------------------------
MAB_2399|M.abscessus_ATCC_1997 AIAVVFAAAVAQTTRIAPGMKQEKQGLLASIRSEQRDSGALESTRDRLSS
Rv1823|M.tuberculosis_H37Rv KVDDVRRIVLADDAEGQRLLARLDVLSLAAASAPVVGPGLTVTVTDPGAS
Mb1854|M.bovis_AF2122/97 KVDDVRRIVLADDAEGQRLLARLDVLSLAAASAPVVGPGLTVTVTDPGAS
MMAR_2700|M.marinum_M KVDDVQRLALADDVEGQRLLTQLDALNLAAASTPVIGPGLTVTVTDPGVG
MUL_3042|M.ulcerans_Agy99 KVDDVQRLALADDVEGQRLLTQLDALNLAAASTPVIGPGLTVTVTDPGVG
MAV_2892|M.avium_104 KVDDVQRHALADDAEGQRLLKRLDALGLAAASTAVIGPGLKVTVTDPGAG
Mflv_3406|M.gilvum_PYR-GCK EVNAARRSRLEGDAEGRQLLAGLDEANYAAAATPVIGPGLTVTVTDPGMS
Mvan_3139|M.vanbaalenii_PYR-1 EVDAERRSRLEGDATGRQLLTDLDQAEQAAAATPVIGPGVTITVTDPGMS
MSMEG_3651|M.smegmatis_MC2_155 AVDTEQRRRLGMDADGQRLLDDLDSANVAAAAVPMIGPGLTVTVTDPGMS
TH_1122|M.thermoresistible__bu ------------------------VADFAAAATPVRGPGLTVTVTDPGAT
MAB_2399|M.abscessus_ATCC_1997 EVAGARRSQLEGNEQGKELLNRLDQLGLAAASTEVRGPALVVTLADPGSG
***:. : **.: :*::***
Rv1823|M.tuberculosis_H37Rv PNLSDVSKQRVSGSQQIILDRDLQLVVNSLWESGAEAISIDGVRIGPNVT
Mb1854|M.bovis_AF2122/97 PNLSDVSKQRVSGSQQIILDRDLQLVVNSLWESGAEAISIDGVRIGPNVT
MMAR_2700|M.marinum_M PNLSDASKQRVSGSQQIILDRDLQLVLNSLWASGAEAVSVDGVRIGPNVT
MUL_3042|M.ulcerans_Agy99 LNLSDASKQRVSGSQQIILDRDLQLVLNSLWASGAEAVSVDGVRIGPNVT
MAV_2892|M.avium_104 PNLSDVSKQRVSGSRQIILDRDLQLVVNSLWAGGAEAVSVGGVRIGPTVT
Mflv_3406|M.gilvum_PYR-GCK RDLTDVSKQRVEGSRQVILDRDLQLVVNSLWAGGAEAISVGGVRVGPNVT
Mvan_3139|M.vanbaalenii_PYR-1 PNLTDVSKQRVEGSMQVILDRDLQLVVNSLWVSGAEAISVGGVRIGPNVT
MSMEG_3651|M.smegmatis_MC2_155 RDLSDVSKQRVAGSQQVILDRDLQLVVNSLWASGAEAISVGGVRVGAGVT
TH_1122|M.thermoresistible__bu RDLSDLSKERVPGSRQVILDRDLQLVVNSLWISGAEAIAIDEVRIGPNVT
MAB_2399|M.abscessus_ATCC_1997 GDLSDVSKERIPRSQQVILDRDMQLVVNSLWTSGAEAISVSDVRIGPNVT
:*:* **:*: * *:*****:***:**** .****:::. **:*. **
Rv1823|M.tuberculosis_H37Rv IRQAGGAILVDNNPTSSPYTILAVGPPHAMQDVFDRSAGLYRLRLLETSY
Mb1854|M.bovis_AF2122/97 IRQAGGAILVDNNPTSSPYTILAVGPPHAMQDVFDRSAGLYRLRLLETSY
MMAR_2700|M.marinum_M IRQAGGAILVDNNPTSSPYTILAVGPPHAMRDAFDRSPGMRRLKLLEISY
MUL_3042|M.ulcerans_Agy99 IRQAGGAILVDNNPTSSPYTILAVGPPHAMRDAFDRSPGMRRLKLLEISY
MAV_2892|M.avium_104 IRQAGGAILVDNNPTSSPYTILAIGPPHALRDAFDTSPGMQRLRLLQISY
Mflv_3406|M.gilvum_PYR-GCK IRQAGGGILVDNQPISSPYAILAVGPPNALDDNFTRSAGLQRLRLLEGSY
Mvan_3139|M.vanbaalenii_PYR-1 MRQAGGGILVDNQPVSSPYAILAVGPPNAMQDNFNRSAGLQRLRLLEASY
MSMEG_3651|M.smegmatis_MC2_155 IRQAGGGILVDNQPITSPYEIVAIGPPNAMAQVFDRSPALQRLRLLETSY
TH_1122|M.thermoresistible__bu IRQAGGGILVDNRPISSPYVIRAVGPPRGMQDQFDRSTALQRLRLLESAY
MAB_2399|M.abscessus_ATCC_1997 MRQAGGAILVDNQPTSSPYRIVAIGPANTIKSAFERSPGMARMRLLQKSY
:*****.*****.* :*** * *:**.. : . * *..: *::**: :*
Rv1823|M.tuberculosis_H37Rv GVGVSVNVGDGLALPAGATRDVKFAKQIGP---
Mb1854|M.bovis_AF2122/97 GVGVSVNVGDGLALPAGATRDVKFAKQIGP---
MMAR_2700|M.marinum_M GVGVSVNVGDGLALPAGSIRDVKFAKQIGP---
MUL_3042|M.ulcerans_Agy99 GVGVSVNVGDGLALPAGSIRDVKFAKQIGP---
MAV_2892|M.avium_104 GVVVTVDVADGLTLPAGSVRDVKFAKQIGPQ--
Mflv_3406|M.gilvum_PYR-GCK GVVVNVSSDDGLVLPAGSVREIRFARQMGP---
Mvan_3139|M.vanbaalenii_PYR-1 GVVVNVSGGDGLVLPAGSVRDINFAKQMGLK--
MSMEG_3651|M.smegmatis_MC2_155 GAGVNVSMGDGLDVPAVAVRDVRFGKQIG----
TH_1122|M.thermoresistible__bu GVGVNVSVEDDLTVPAATAREVNFATELGR---
MAB_2399|M.abscessus_ATCC_1997 GIRLTLATQENVQMAPAASRDVKYAKEIPAGNR
* :.: :.: :.. : *::.:. ::