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MRLTHPTPCPENGETMIDRRRSAWRFSVPLVCLLAGLLLAATHGVSGGTEIRRSDAPRLVDLVRRAQASV NRLATEREALTTRIDSVHGRSVDTALAAMQRRSAKLAGVAAMNPVHGPGLVVTLQDAQRDANGRFPRDAS PDDLVVHQQDIEAVLNALWNAGAEAIQMQDQRIIAMSIARCVGNTLLLNGRTYSPPYTIAAIGDAAAMQA ALAAAPLVTLYKQYVVRFGLGYCEEVHPDLQIVGYADPVRMHFAQPAGPLDY
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv0012 | - | - | 100% (262) | PROBABLE CONSERVED MEMBRANE PROTEIN |
| M. tuberculosis H37Rv | Rv1823 | - | 1e-17 | 29.80% (245) | hypothetical protein Rv1823 |
| M. tuberculosis H37Rv | Rv1825 | - | 3e-09 | 27.23% (191) | hypothetical protein Rv1825 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0012 | - | 1e-147 | 99.24% (262) | hypothetical protein Mb0012 |
| M. gilvum PYR-GCK | Mflv_0814 | - | 5e-93 | 68.55% (248) | hypothetical protein Mflv_0814 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0031 | - | 2e-76 | 65.64% (227) | hypothetical protein MAB_0031 |
| M. marinum M | MMAR_0014 | - | 1e-109 | 78.54% (247) | hypothetical protein MMAR_0014 |
| M. avium 104 | MAV_0016 | - | 1e-113 | 81.38% (247) | hypothetical protein MAV_0016 |
| M. smegmatis MC2 155 | MSMEG_0027 | - | 3e-98 | 73.36% (244) | hypothetical protein MSMEG_0027 |
| M. thermoresistible (build 8) | TH_0293 | - | 6e-97 | 71.54% (246) | PROBABLE CONSERVED MEMBRANE PROTEIN |
| M. ulcerans Agy99 | MUL_0016 | - | 1e-109 | 78.14% (247) | hypothetical protein MUL_0016 |
| M. vanbaalenii PYR-1 | Mvan_0020 | - | 8e-95 | 69.80% (245) | hypothetical protein Mvan_0020 |
CLUSTAL 2.0.9 multiple sequence alignment
Rv0012|M.tuberculosis_H37Rv ---------MRLTHPTPCPENGETMIDRRRSAWRFSVPLVCLLAGLLLAA
Mb0012|M.bovis_AF2122/97 ---------MRLTHPTPCPENGETMIDRRRSAWRFSVPLVCLLAGLLLAA
MAV_0016|M.avium_104 ------------------------MVQTRQSPWRFGVPLVCLLAGLLLAA
MMAR_0014|M.marinum_M ------------------------MTDERRSPWRFGVPLVCLLAGLLLAA
MUL_0016|M.ulcerans_Agy99 ------------------------MTDERRSPWRFGVPLVCLLAGLLLAA
Mflv_0814|M.gilvum_PYR-GCK -------------------MTDRRELPRKRSVWRFGVPVVCVAAGLLLGT
Mvan_0020|M.vanbaalenii_PYR-1 MCRESLTQAHLAAPKETTPMDHRSTRTGKRSVWRFGVPVICVAAGLLLGA
MSMEG_0027|M.smegmatis_MC2_155 -------------------MDQPS-----RSRWRLGVPVICLLAGLLLAA
TH_0293|M.thermoresistible__bu ---MDQQPAERSSGDEAGRTDRTDGAQRRRSPWRYGVPLVCLAAGLLLSA
MAB_0031|M.abscessus_ATCC_1997 ------------------------------------MPLVCALAGFLLAA
:*::* **:**.:
Rv0012|M.tuberculosis_H37Rv THGVSGGTEIRRSDAP--RLVDLVRRAQASVNRLATEREALTTRIDSVHG
Mb0012|M.bovis_AF2122/97 THGVSGGTEIRRSDAP--RLVDLVRRAQASVNRLATEREALTTRIDSVHG
MAV_0016|M.avium_104 THGVSGGAEIRRSDAP--RLVDLVRETQASVNRLSAQREQLAAKIDAAHG
MMAR_0014|M.marinum_M THGVSGGAEIRRSDAP--RLVDLVRQSQSSVNRLSAERDALTARIDANHL
MUL_0016|M.ulcerans_Agy99 THGVSGGAEIRRSDAP--RLVDLVRQSQSSVNRLSAERDALTARIDANHL
Mflv_0814|M.gilvum_PYR-GCK TYGVSGGDEIRRSDAP--RLVDLVREAQQSVDRLSAEQGALALRFDNHHG
Mvan_0020|M.vanbaalenii_PYR-1 THGVSGGDEIRRSDAP--RLVDLVRESQQSVDRLGAERDSLSLEIDNHHG
MSMEG_0027|M.smegmatis_MC2_155 THGVSGGDEIRRSDSP--RLVDLVREAQQSVDRLAAQRDALALEVDSHHG
TH_0293|M.thermoresistible__bu THAVAGGDEIRRSDAP--RLVDLVRETQESVDRLTAERDALANQRDNRHG
MAB_0031|M.abscessus_ATCC_1997 THTVSGGSEIRRGDSPSPRLVDLVRETQKSVDKLSGTRDGLANEMAAARE
*: *:** ****.*:* *******.:* **::* : *: . :
Rv0012|M.tuberculosis_H37Rv RS--VDTALAAMQRRSAKLAGVAAMNPVHGPGLVVTLQDAQRDANGRFPR
Mb0012|M.bovis_AF2122/97 RS--VDTALAAMQRRSAELAGVAAMNPVHGPGLVVTLQDAQRDANGRFPR
MAV_0016|M.avium_104 RS--SDAALAAMLRRSAQLAGEAGMSPVHGPGLVVTLQDAQRDANGRFPR
MMAR_0014|M.marinum_M RS--SDAALTAMLRRARELASEADMDPAHGPGLVVTLNDAQRDANGRFPR
MUL_0016|M.ulcerans_Agy99 RS--SDAVLTAMLRRARELASEADMDPAHGPGLVVTLNDAQRDANGRFPR
Mflv_0814|M.gilvum_PYR-GCK GSPGAAAALTAMTDRGNALAAQAGLTPLRGPGLVVTLNDAQRDAQGRFPR
Mvan_0020|M.vanbaalenii_PYR-1 GSPGADAALSAIVERGDLLAAQAGMTPLRGPGLVVTLNDAQRDAQGRFPR
MSMEG_0027|M.smegmatis_MC2_155 GSPSSHAALDAITARTAQLAVDAGMDPMRGPGLVVTLNDAQRDAEGRFPR
TH_0293|M.thermoresistible__bu ASPGAGSALTAITERSARLADPAGLDPLRGPGLVVTLTDAQRDAEGRFPR
MAB_0031|M.abscessus_ATCC_1997 QSAGGDSQVAAALAETAEVADAAGVRPVTGPGLVVTLTDAKRDAYGRFPR
* : : * . :* * : * ******** **:*** *****
Rv0012|M.tuberculosis_H37Rv DASPDDLVVHQQDIEAVLNALWNAGAEAIQMQD-QRIIAMSIARCVGNTL
Mb0012|M.bovis_AF2122/97 DASPDDLVVHQQDIEAVLNALWNAGAEAIQMQD-QRIIAMSIARCVGNTL
MAV_0016|M.avium_104 DASPDDLVVHQQDIQAVLNALWSAGAEAIQMQD-QRIIATSVPRCVGNTL
MMAR_0014|M.marinum_M DASPDDLVVHQQDIDAVLNAMWSAGAEAIQMQD-QRIIANSVVRCVGNTL
MUL_0016|M.ulcerans_Agy99 DASPDDLVVHQQDIDAVLNAMWSAGAEAIQMQG-QRIIANSVVRCVGNTL
Mflv_0814|M.gilvum_PYR-GCK DASPDDLVVHQQDIQGVINAMWSAGAEGIQVQD-QRIIATSAPRCVGNTL
Mvan_0020|M.vanbaalenii_PYR-1 DASPDDLVVHQQDIQAVINALWSAGAEGIQVQD-QRIIGTSAPRCVGNTL
MSMEG_0027|M.smegmatis_MC2_155 DAAPDDLVVHQQDIQAVLNALWSAGAEGIQMQD-QRIIATSAPRCVGNTL
TH_0293|M.thermoresistible__bu DATPDDLVVHQQDIEAVLNALWAGGAEGIQMQD-QRLIATSAPRCVGNTL
MAB_0031|M.abscessus_ATCC_1997 DASPDDLVVHQQDVEGVLNALWSAGAEAIQMQDDQRLVASSVPRCVGNTL
**:**********::.*:**:* .***.**:*. **::. * *******
Rv0012|M.tuberculosis_H37Rv LLNGRTYSPPYTIAAIGDAAAMQAALAAAPLVTLYKQYVVRFGLGYCEEV
Mb0012|M.bovis_AF2122/97 LLNGRTYSPPYTIAAIGDAAAMQAALAAAPLVTLYKQYVVRFGLGYREEV
MAV_0016|M.avium_104 LLNGRTYSPPYTITAIGNAAAMQAALAAAPLVTLYKQYAVRFGLGYQEEV
MMAR_0014|M.marinum_M LLNGRTYSPPYIITAIGDPAAMQAALEAAPLVVLYKQYVVRFGLGYREEA
MUL_0016|M.ulcerans_Agy99 LLNGRTYSPPYIITAIGDAAAMQAALEAAPLVVLYKQYVVRFGLGYREEA
Mflv_0814|M.gilvum_PYR-GCK LLNGRTYSPPYVISAVGDPGAMQAALAESPLVTLYKRYAVRFGLGYTEET
Mvan_0020|M.vanbaalenii_PYR-1 LLNGRTYSPPYVISAVGDPGAMQAALAAAPLVTLYKRYAVRFGLGYTEES
MSMEG_0027|M.smegmatis_MC2_155 LLNGRTYSPPYVITAIGDAAAMQAALAEAPLVTLYKQYVLRFGLGYTEEP
TH_0293|M.thermoresistible__bu LLNGRTYSPPYVITAVGDVPRMQAALADAPLVRLYKQYVVRFGLGYTEEP
MAB_0031|M.abscessus_ATCC_1997 LLHGRTYSPPYVITAIGDADAMQAALDAAPLVTLYRQYVARFGLGYTVTR
**:******** *:*:*: ***** :*** **::*. ******
Rv0012|M.tuberculosis_H37Rv HPDLQIVGYADPVRMHFAQPAGPLDY
Mb0012|M.bovis_AF2122/97 HPDLQIVGYADPVRMHFAQPAGPLDY
MAV_0016|M.avium_104 RSDVQVVGHFEPDRLHFAQPNGPIGY
MMAR_0014|M.marinum_M KSDVNVAGYSEPVRMHYAQPLGPVGY
MUL_0016|M.ulcerans_Agy99 KSDVNVAGYSEPVRMHYAQPLGPVGY
Mflv_0814|M.gilvum_PYR-GCK R-DVELVGHSESVRMKFAQPMGPLGY
Mvan_0020|M.vanbaalenii_PYR-1 R-EVELVGHQEPVRMKYAQPLGPVGY
MSMEG_0027|M.smegmatis_MC2_155 KAEVTLAGHTEPVRMRYAKPAGPLGY
TH_0293|M.thermoresistible__bu RAEVEIVGYREPVRMRFATPAGPIGY
MAB_0031|M.abscessus_ATCC_1997 GHHLEVAGYRDAVGPGRAVPLQGH--
.: :.*: :. * *