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MKAQRSFGLALSWPRVTAVFLVDVLILAVASHCPDSWQADHHVAWWVGVGVAAVVTLLSVVSYHGITVIS GLATWVRDWSADPGTTLGAGCTPAIDHQRRFGRDTVGVREYNGRLVSVIEVTCGESGPSGRHWHRKSPVP MLPVVAVADGLRQFDIHLDGIDIVSVLVRGGVDAAKASASLQEWEPQGWKSEERAGDRTVADRRRTWLVL RMNPQRNVAAVACRDSLASTLVAATERLVQDLDGQSCAARPVTADELTEVDSAVLADLEPTWSRPGWRHL KHFNGYATSFWVTPSDITSETLDELCLPDSPEVGTTVVTVRLTTRVGSPALSAWVRYHSDTRLPKEVAAG LNRLTGRQLAAVRASLPAPTHRPLLVIPSRNLRDHDELVLPVGQELEHATSSFVGQ
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv1797 | - | - | 100% (406) | hypothetical protein Rv1797 |
| M. tuberculosis H37Rv | Rv3882c | - | 7e-08 | 25.55% (274) | hypothetical protein Rv3882c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1825 | - | 0.0 | 100.00% (406) | hypothetical protein Mb1825 |
| M. gilvum PYR-GCK | Mflv_0756 | - | 3e-08 | 26.41% (284) | hypothetical protein Mflv_0756 |
| M. leprae Br4923 | MLBr_01537 | - | 1e-152 | 67.98% (406) | putative secreted protein |
| M. abscessus ATCC 19977 | MAB_3760 | - | 6e-17 | 25.74% (338) | hypothetical protein MAB_3760 |
| M. marinum M | MMAR_2679 | - | 1e-172 | 71.43% (406) | hypothetical protein MMAR_2679 |
| M. avium 104 | MAV_2917 | - | 1e-147 | 66.42% (402) | hypothetical protein MAV_2917 |
| M. smegmatis MC2 155 | MSMEG_0082 | - | 5e-08 | 25.98% (254) | hypothetical protein MSMEG_0082 |
| M. thermoresistible (build 8) | TH_1275 | - | 1e-06 | 24.83% (294) | POSSIBLE CONSERVED MEMBRANE PROTEIN |
| M. ulcerans Agy99 | MUL_3078 | - | 1e-171 | 70.69% (406) | hypothetical protein MUL_3078 |
| M. vanbaalenii PYR-1 | Mvan_0091 | - | 1e-07 | 26.21% (290) | hypothetical protein Mvan_0091 |
CLUSTAL 2.0.9 multiple sequence alignment
Rv1797|M.tuberculosis_H37Rv MKAQRSFGLALSWPRVTAVFLVDVLILAVASHCPDSWQADHHVAWWVGVG
Mb1825|M.bovis_AF2122/97 MKAQRSFGLALSWPRVTAVFLVDVLILAVASHCPDSWQADHHVAWWVGVG
MMAR_2679|M.marinum_M MKAQRRFGLALSWARLTTVFVIDLLILIVASHCPDSWQGENRIAWWVGVG
MUL_3078|M.ulcerans_Agy99 MKAQRRFGLALSWARLTTVFVIDLLILIVASHCPDSWQGENRIAWWVGVG
MLBr_01537|M.leprae_Br4923 MKAQRRLGLALSWSRVTTVFVVAIVVLVLASHVPELWQAGHHVAWCVGVG
MAV_2917|M.avium_104 MKAQRRLGLSLTWPRLTTVFLVDIVIMVVASHCPESWQGTYRIAFWVGVG
Mflv_0756|M.gilvum_PYR-GCK -MSRFLSIFGVRFTTGHALWAAVLVPACILIFA-------QLNLLWLGIT
Mvan_0091|M.vanbaalenii_PYR-1 -MSRFASIFGLRFTTGHALWAAALIPACILVFA-------RLELLWLGIT
MSMEG_0082|M.smegmatis_MC2_155 -MNFLR-QFGFRFTTGHGIWAATLIPACIAICM-------HFDLLWLGIT
TH_1275|M.thermoresistible__bu -MKSLRNLFGMRFSTGHGIWAAVLIPAVVVLFE-------RLEMLWLGVV
MAB_3760|M.abscessus_ATCC_1997 ---MTSSGAAPEQVRRATMPIQIMVISQLLVLAAVLISLLFGWPWWAALL
. : :: : .:
Rv1797|M.tuberculosis_H37Rv VAAVVTLLSVVSYHGITVISGLATWVRDWSADPGTTLGAGCTPAIDHQRR
Mb1825|M.bovis_AF2122/97 VAAVVTLLSVVSYHGITVISGLATWVRDWSADPGTTLGAGCTPAIDHQRR
MMAR_2679|M.marinum_M IAVLVTLLSVVTYRGITVTSGITAWLWDWSADPGTALGAGCTPAVDHQRR
MUL_3078|M.ulcerans_Agy99 IAVLVTLLSVVTYRGITVTSGITAWLWDWSADPGTALGAGCTPAVDHQRR
MLBr_01537|M.leprae_Br4923 ITVVVMVLVLVSYHGITLMSGLATWVWDCFADPRAALAAGCTPAIDHQRR
MAV_2917|M.avium_104 LAVLVTLLSLVTYHGITVASGLATWLWDWSADPGSALAAGCTPALDHQRR
Mflv_0756|M.gilvum_PYR-GCK LAVLIALCALVTIRGRRIT-GWIAALFAWRRRHRQPPPAPSEPAVGATVV
Mvan_0091|M.vanbaalenii_PYR-1 LGVLIGLASVVTIRGRRLT-GWVAALFAWRRRHRQPPPTPSEPAVGATVI
MSMEG_0082|M.smegmatis_MC2_155 LGALIALFSVLTIRGLRIT-GWVRAIFSWRRRHRSTPDIASEPAVGSTVM
TH_1275|M.thermoresistible__bu VAVFIAPASVLTIRGRRLT-GWVAAVFSWRRRHRVPPARPSEPAVGATVA
MAB_3760|M.abscessus_ATCC_1997 IAIVSLALVLGRWGGQTVRHWAVTGFKYLTGRTYRSSGSIADTPSGQDSW
: . : * : . . . .. .
Rv1797|M.tuberculosis_H37Rv FGRDTVGVREYNGRLVSVIEVTCGESGPSGRHWHRKSPVPMLPVVAVADG
Mb1825|M.bovis_AF2122/97 FGRDTVGVREYNGRLVSVIEVTCGESGPSGRHWHRKSPVPMLPVVAVADG
MMAR_2679|M.marinum_M FGRDTVGVREHHGRLVTVITVDDGEGDAAGRHRHRTTQSAVVPVATVAEN
MUL_3078|M.ulcerans_Agy99 FGRDTVGVREHHGRLVTVITVDDGEGDAAGRHRHRTTQSAVVPVATVAEN
MLBr_01537|M.leprae_Br4923 FGRDVVGVREYKGRLVTVIAVDDGEDDPVGRHRHRTTPAG-LPVQAVADG
MAV_2917|M.avium_104 FGRDKVGVREYKGQLVSVIAVNGGEDETGSRHRHR-AASPTLLVAAVASG
Mflv_0756|M.gilvum_PYR-GCK PG-DHVALRWQHGYLVSAIELIPRPFTPTVIVNGEAFTDDVIDSRQLEKL
Mvan_0091|M.vanbaalenii_PYR-1 PG-DHVALRWQDDYLVSVIELVPRPFTPTVIVNGEAFTDDVVETRLVEDL
MSMEG_0082|M.smegmatis_MC2_155 PG-DHVAVRWQGDYLIAVIELVPRPFTPTVIVNGSAMTDDVVNTKLVERL
TH_1275|M.thermoresistible__bu PG-DHVAVRWQGDHLVSAIELVPRPFTPTVLVNGKAFTDDLLDTRLVEQL
MAB_3760|M.abscessus_ATCC_1997 TG-----TRWENGKLITVLEISATQRHPSVITPDHCATDSLVPLRVLREC
* * . *::.: : . : :
Rv1797|M.tuberculosis_H37Rv LRQFDIHLDGIDIVSVLVRGGVDAAKASAS-----LQEWEPQGWKSEERA
Mb1825|M.bovis_AF2122/97 LRQFDIHLDGIDIVSVLVRGGVDAAKASAS-----LQEWEPQGWKSEERA
MMAR_2679|M.marinum_M LRQFDVQLDGVDIVTVEVRGGAEAARASAS-----LDEWGPEEWG---MV
MUL_3078|M.ulcerans_Agy99 LRQFDVQLDGVDIMTVEVRGGAEAARASAS-----LDEWGPEEWG---MV
MLBr_01537|M.leprae_Br4923 LRQFDIRLDSIDIVSVKIRRGGNAAKFSA------LDNWGSEEWG---LV
MAV_2917|M.avium_104 LRQFDIHLDDIDIVSVKVRRGGPDARSAELS---KLDDFGPEEWD---VV
Mflv_0756|M.gilvum_PYR-GCK LAAYCPDLE-ADIVSAGYRVGRTAPAALVGLYEQ--------------VV
Mvan_0091|M.vanbaalenii_PYR-1 LTAYCPDLE-ADIVSAGYRVGKTAPAALVALYEQ--------------VV
MSMEG_0082|M.smegmatis_MC2_155 LEAHCPDLE-ADVVSAGYRVGKTAPASLIALYEQ--------------VV
TH_1275|M.thermoresistible__bu LTAHCPDLE-ADIVSAGYRVGKTAPASLLALYEQ--------------VL
MAB_3760|M.abscessus_ATCC_1997 MHQNDIELESIDVISNGQRTAQGTVLRGGYDR----------------LV
: *: *::: * .
Rv1797|M.tuberculosis_H37Rv GDRTVADRRRTWLVLRMNPQRNVAAVACRD----SLASTLVAATERLVQD
Mb1825|M.bovis_AF2122/97 GDRTVADRRRTWLVLRMNPQRNVAAVACRD----SLASTLVAATERLVQD
MMAR_2679|M.marinum_M GESPAANRRRTWLILRMNPQRNVAAIASRD----SLASTLVTATERLAQV
MUL_3078|M.ulcerans_Agy99 GESPAANRRRTWLILRMNPQRNVAAIASRD----SLASTLVTATERLAQV
MLBr_01537|M.leprae_Br4923 CACPPTYQRCTWLVLRMNPQHNVVAVAARD----SLASTLVAATERLAQD
MAV_2917|M.avium_104 GDEPTSYIRRTWLVLRMNPQRNVAAVAARD----SLASTLVAATERLAQD
Mflv_0756|M.gilvum_PYR-GCK GPYPAPARRRTWIVLRADPDKTRKSALRRDVGVSGLAQYVVSSTTRIADH
Mvan_0091|M.vanbaalenii_PYR-1 GPYPAPASRRTWIVLRADPDKTRKSALRRNEGVAGLAQYLVSSTTRIADH
MSMEG_0082|M.smegmatis_MC2_155 GPYPAPANRRTWIVLRADPEKTQRSAHRRDSGVSGLARYLVASATRIADQ
TH_1275|M.thermoresistible__bu GPYPAPANRRTWIVLRADPERTQKSARRRDVGVAGLSRYLVASTTRIADQ
MAB_3760|M.abscessus_ATCC_1997 GPLPAVAIRTVWVVLRFDPGANVDAVFRRGGGRRGAERCAVIATARVRRA
. * .*::** :* . : *. . * :: *:
Rv1797|M.tuberculosis_H37Rv LDGQSCAARPVTADELTEVDSAVLADLEPTWSRPG-----WRHLKHFNGY
Mb1825|M.bovis_AF2122/97 LDGQSCAARPVTADELTEVDSAVLADLEPTWSRPG-----WRHLKHFNGY
MMAR_2679|M.marinum_M LDGQSCAARPLAADELAEVDSAILAELEPTWSRPG-----WRHLKHFNGY
MUL_3078|M.ulcerans_Agy99 LDGQSCAARPLAADELAEVDSTILAELAPTWSRPG-----WRHLKHFNGY
MLBr_01537|M.leprae_Br4923 LDGQNCAARPLAAGELAEVDSAVLADLEPTWSYPG-----WRHIKYVNGF
MAV_2917|M.avium_104 LDGLTCAARPLTAEEIAEVDRAVLADLEPTWSRPG-----WRRLKHFNGF
Mflv_0756|M.gilvum_PYR-GCK LASNGIDARPARSFDDFDGATEISFERETWSMVKGRS--TFTAAYHAPGG
Mvan_0091|M.vanbaalenii_PYR-1 LASKGVDARPARSFDDFDRATEISFERETWSMVKGRS--TFTAAYHAPGG
MSMEG_0082|M.smegmatis_MC2_155 LASNGVDARCCRSFDDYEKATEISYERETWSSIKGRS--TFTAAYTAPGG
TH_1275|M.thermoresistible__bu LASHGVDARCARSFDDLDRATEISFERETWSSIKGRS--TFTAAYSAPGG
MAB_3760|M.abscessus_ATCC_1997 LAAAHCASTILQAGQIHRISAEMLRQYAGAPMHEDWSGLTLIDSYNVAMG
* . : : : : : .
Rv1797|M.tuberculosis_H37Rv ATSFWVTPSD----------------------ITSETLDELCLPDSPEVG
Mb1825|M.bovis_AF2122/97 ATSFWVTPSD----------------------ITSETLDELCLPDSPEVG
MMAR_2679|M.marinum_M ATSFWVTPAD----------------------INAETLDEVWLSDAPEVG
MUL_3078|M.ulcerans_Agy99 ATSFWVTPAD----------------------INAETLDEVWLSDAPEVG
MLBr_01537|M.leprae_Br4923 ATSFWVTPSD----------------------IDSETLNELWLSDLPDIK
MAV_2917|M.avium_104 VTSLWLSPSD----------------------ITTDKLEELWDDDT---F
Mflv_0756|M.gilvum_PYR-GCK PDVWWSARADYT--------LTRVRIVPGAAPTATVLLTTLANPSTPRGF
Mvan_0091|M.vanbaalenii_PYR-1 PDVWWSARADHT--------LTRMRIVPGSAPTTTVLLTTLANPSTPRGF
MSMEG_0082|M.smegmatis_MC2_155 PDMWWSARADHT--------ITRVRVRPGAAPSSAILLTTLANPTTPRGF
TH_1275|M.thermoresistible__bu PDVWWSARADHT--------ITRLRVRPGAPPTSTVLLTTLANPTTPRGF
MAB_3760|M.abscessus_ATCC_1997 IDPWYITDATLTGLWARPTLETSVTVRLRPAAKGRTSVGALVRWATDEQL
: : : : :
Rv1797|M.tuberculosis_H37Rv TTVVTVRLTTRVG-------------------------------------
Mb1825|M.bovis_AF2122/97 TTVVTVRLTTRVG-------------------------------------
MMAR_2679|M.marinum_M ATVLTLRLVMRAG-------------------------------------
MUL_3078|M.ulcerans_Agy99 ATVLTLRLVMRAG-------------------------------------
MLBr_01537|M.leprae_Br4923 ATVITIRLASRSC-------------------------------------
MAV_2917|M.avium_104 ATVLTIRLTARAG-------------------------------------
Mflv_0756|M.gilvum_PYR-GCK SCLYGGQRAALLGESPVTDRH-------------------------YELP
Mvan_0091|M.vanbaalenii_PYR-1 SCLFGGQRAALLGENPVTDRH-------------------------YELP
MSMEG_0082|M.smegmatis_MC2_155 SCLFGGQRAALQGIVPVSDKH-------------------------YDLP
TH_1275|M.thermoresistible__bu SCLFGGQRAALEGLSPVTDKH-------------------------HELP
MAB_3760|M.abscessus_ATCC_1997 PVRHSTGMTSLNGSQRDAFFAGLPVGAIGLEYLTRSIEMSNEELDGIHLP
. .
Rv1797|M.tuberculosis_H37Rv --------SPALS--AWVRYHSDTRLPKEVAAGLNRLTGRQLAAVRAS--
Mb1825|M.bovis_AF2122/97 --------SPALS--AWVRYHSDTRLPKEVAAGLNRLTGRQLAAVRAS--
MMAR_2679|M.marinum_M --------EPRLS--AWVRYHSDERLPKELSVGLNRLTGRQLAAVRAS--
MUL_3078|M.ulcerans_Agy99 --------EPRLS--AWVRYHSDERLPKELSVGLNRLTGRQLAAVRAS--
MLBr_01537|M.leprae_Br4923 --------QTRLS--AWVRHHSETRLSKEACRGLNQLTGRQLAAVRAS--
MAV_2917|M.avium_104 --------RPHVS--AWVRYHTEKRLRRNISSGLNRLTGRQLAAVRAS--
Mflv_0756|M.gilvum_PYR-GCK IGSAGVLVGETAD--RYPVYMPFDDTDVSINLGNARLFTQFVVRSAAAGA
Mvan_0091|M.vanbaalenii_PYR-1 IGSAGVLVGETAD--RYPVYMPFDDVDVSINLGNARLFTQFVVRSAAAGA
MSMEG_0082|M.smegmatis_MC2_155 IGSAGVLVGETAD--RYPVYMPFDNVDVSINLGDARLFTQFVIRSAAAGA
TH_1275|M.thermoresistible__bu IGSAGVLVGETVD--RYPVYMPFDDVDVSINLGDARLFTQFVVRSAAAGG
MAB_3760|M.abscessus_ATCC_1997 TSGCGQLIGSDMSGRAIATRLSGQGVHTVVVRAELYVCQQVVLRAVAIGA
. . . : : : *
Rv1797|M.tuberculosis_H37Rv --------------------------------------------------
Mb1825|M.bovis_AF2122/97 --------------------------------------------------
MMAR_2679|M.marinum_M --------------------------------------------------
MUL_3078|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01537|M.leprae_Br4923 --------------------------------------------------
MAV_2917|M.avium_104 --------------------------------------------------
Mflv_0756|M.gilvum_PYR-GCK NVTLQPQFGEFAGYVNAQIGPTAKVAWPHAT----------------TYL
Mvan_0091|M.vanbaalenii_PYR-1 AVTLQPQFEEFAGFVNARIGQVAKVAWPHAT----------------TYL
MSMEG_0082|M.smegmatis_MC2_155 VVTLGPQFREFATMINGRVGRTPRIGWPNAT----------------TYL
TH_1275|M.thermoresistible__bu VVTLLPQFREFASLINARVGPEAKISWPNAT----------------TYL
MAB_3760|M.abscessus_ATCC_1997 LVVVYTDRPHMWDVMVTSIGDANRIQFASGPGFIDPRCTLAVVDGMQPTA
Rv1797|M.tuberculosis_H37Rv LPAPTHRPLLVIPSRNLR-DHDELVLPVGQELEHATSSFVGQ--------
Mb1825|M.bovis_AF2122/97 LPAPTHRPLLVIPSRNLR-DHDELVLPVGQELEHATSSFVGQ--------
MMAR_2679|M.marinum_M LPVPSTRAQLVVSSRELL-DHDELELPVGQTQEHATSATTGQ--------
MUL_3078|M.ulcerans_Agy99 LPVPSTRAQLVVSSRELL-DHDELELPVGQTQEHATSATTGQ--------
MLBr_01537|M.leprae_Br4923 LPAPATRPVLVVPSRELS-DHDELVLPVGQGREGSASLFAGQ--------
MAV_2917|M.avium_104 LPVPTARPLLEVPSRPLRADDDELSLSLAAPRESAAGVPAAQ--------
Mflv_0756|M.gilvum_PYR-GCK RPQPGVGRVVLRDNFIATPRHKELPIRLINPREESRYQMALEP-------
Mvan_0091|M.vanbaalenii_PYR-1 RPHPGVGRVMLRDDFIATPRHKQLPIRLINPREESRYQMVLEP-------
MSMEG_0082|M.smegmatis_MC2_155 GPHQGVGRVILRPNFIDTPRHRQLPIQLINPREESRYQMALEQ-------
TH_1275|M.thermoresistible__bu GPHPGIGRVILRHNFIDTPRHRQLPIRLINPREESRYQMALEG-------
MAB_3760|M.abscessus_ATCC_1997 LPSNCTALHIISSEYDALPARPDVIIDQPNGYGDHILLTAGGETIQVRLV
* : . :: : .
Rv1797|M.tuberculosis_H37Rv ------------------
Mb1825|M.bovis_AF2122/97 ------------------
MMAR_2679|M.marinum_M ------------------
MUL_3078|M.ulcerans_Agy99 ------------------
MLBr_01537|M.leprae_Br4923 ------------------
MAV_2917|M.avium_104 ------------------
Mflv_0756|M.gilvum_PYR-GCK ------------------
Mvan_0091|M.vanbaalenii_PYR-1 ------------------
MSMEG_0082|M.smegmatis_MC2_155 ------------------
TH_1275|M.thermoresistible__bu ------------------
MAB_3760|M.abscessus_ATCC_1997 TVSDELAYLGRPIQAFAQ