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IATTRDREGATMITFRLRLPCRTILRVFSRNPLVRGTDRLEAVVMLLAVTVSLLTIPFAAAAGTAVQDSR SHVYAHQAQTRHPATATVIDHEGVIDSNTTATSAPPRTKITVPARWVVNGIERSGEVNAKPGTKSGDRVG IWVDSAGQLVDEPAPPARAIADAALAALGLWLSVAAVAGALLALTRAILIRVRNASWQHDIDSLFCTQR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv1733c | - | - | 100% (210) | PROBABLE CONSERVED TRANSMEMBRANE PROTEIN |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1762c | - | 1e-116 | 99.52% (210) | transmembrane protein |
| M. gilvum PYR-GCK | Mflv_4998 | - | 5e-23 | 35.75% (179) | putative transmembrane protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_3501 | - | 3e-29 | 38.14% (194) | hypothetical protein MMAR_3501 |
| M. avium 104 | MAV_1986 | - | 1e-34 | 44.39% (196) | transmembrane protein |
| M. smegmatis MC2 155 | MSMEG_1127 | - | 1e-37 | 45.13% (195) | transmembrane protein |
| M. thermoresistible (build 8) | TH_3263 | - | 1e-05 | 45.83% (48) | PUTATIVE - |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_1379 | - | 6e-24 | 34.64% (179) | putative transmembrane protein |
CLUSTAL 2.0.9 multiple sequence alignment
Rv1733c|M.tuberculosis_H37Rv MIATTRDRE----------GATMITFRLRLPCR-TILRVFSRNPLVRGTD
Mb1762c|M.bovis_AF2122/97 MIATTRDRE----------GATMITFRLRLPCR-TILRVFSRNPLVRGTD
MMAR_3501|M.marinum_M ----------------------METFKLDPRDW-WIARIAGRNPLLRRAD
MAV_1986|M.avium_104 MTTKGRDHQRLTGGRGGDAAAELETVHIPLPRI-LLAHLFGRNPLVRVSD
MSMEG_1127|M.smegmatis_MC2_155 ----------------------MDTFTLGMPRWPFLLRLWGRHPLVRPTD
TH_3263|M.thermoresistible__bu ----------------------VTGFVIRPPRPPVLTRLYGRNPLLRPID
Mflv_4998|M.gilvum_PYR-GCK ----------------------MQTFTLGFGVW--LRRLASRSPLVRSTD
Mvan_1379|M.vanbaalenii_PYR-1 ----------------------MQSNTFGTRVW--MRRLVARSPIVRGTD
: : : :: .* *::* *
Rv1733c|M.tuberculosis_H37Rv RLEAVVMLLAVTVSLLTIPFAAAAGTAVQDSRSHVYAHQAQTRHPATATV
Mb1762c|M.bovis_AF2122/97 RLEAVVMLLAVTVSLLTIPFAAAAGTAVHDSRSHVYAHQAQTRHPATATV
MMAR_3501|M.marinum_M RVEALVVLIALAASLVAIPVAAVLGAVVFNARADQYAEQAQVRHPVTAEV
MAV_1986|M.avium_104 RVQALIFVLAVAVSLAAVPVAATIGTAVHESRSRVYAEQSQTWRTVTATA
MSMEG_1127|M.smegmatis_MC2_155 RIEAFAVVLTVVVMLVTAPIAAAIGTTVYDARRTMYAEQADTRQVVTATV
TH_3263|M.thermoresistible__bu RVEATIMTLTVVLSVIGLPFALAVTSEQVRADT-----------------
Mflv_4998|M.gilvum_PYR-GCK RVEAAVMTLIVVAGVCAVPIAGAVGTAEYDRLTNSLAAERLTHREVDATV
Mvan_1379|M.vanbaalenii_PYR-1 RIEAAGLLLVVALSILTVPIAGAVGTAEYDRLAHTFAEQRLVKHEVDATA
*::* . : :. : *.* . :
Rv1733c|M.tuberculosis_H37Rv IDHEGVIDSNTTATSAPPRTKITVPARWVVNGIERSGEVNAKPGTKSGDR
Mb1762c|M.bovis_AF2122/97 IDHEGVIDSNTTATSAPPRTKITVPARWVVNGIERSGEVNAKPGTKSGDR
MMAR_3501|M.marinum_M T-------GTT---RNPNTEAVVVQVRWPGAAAQHSGSLQRTSPVKAGQR
MAV_1986|M.avium_104 V-------GDSHPRRDLDSPTVRVPARWQYAGAEHAGDVIAPLNVKAGDR
MSMEG_1127|M.smegmatis_MC2_155 I-------DDDAAQAVLRTNTALMPARWSVAGVEHTGAVDVASTAKTGDV
TH_3263|M.thermoresistible__bu --------------------------------------------------
Mflv_4998|M.gilvum_PYR-GCK VR-------DSRTVSEPYETTYLTEIGWNVGSVARTAEIT-TTRKSAGDR
Mvan_1379|M.vanbaalenii_PYR-1 VS-------DSRGVPQPYEKPYVTEVSWNYAGTTHTAEIR-TRQMSAGDR
Rv1733c|M.tuberculosis_H37Rv VGIWVDSAGQLVDEPAPPARAIADAALAALGLWLSVAAVAGALLALTRAI
Mb1762c|M.bovis_AF2122/97 VGIWVDSAGQLVDEPAPPARAIADAALAALGLWLSVAAVAGALLALTRAI
MMAR_3501|M.marinum_M IQVWVDRDDNLVRPPTPTWHAAVDAVGVTMVILLSMCVVLAALVAAVRTQ
MAV_1986|M.avium_104 VEIWVDDTGSPVTPPD--RTALDEAVAFAVVSWCAVSLPAAALFAAARAA
MSMEG_1127|M.smegmatis_MC2_155 VEIWVDDRGERTSAPTPVGLAAVEAVTGALVLWLVVGGIQGGLLMAIRAL
TH_3263|M.thermoresistible__bu ---------------------APAAAAVAAAVMAGVAVTAAAMCGVTRVV
Mflv_4998|M.gilvum_PYR-GCK LTIWVDDSGDLVRKGLTDGDAATQAVVGALGVWFAVTGLGVATWMLLRLR
Mvan_1379|M.vanbaalenii_PYR-1 VRIWVDDAGNRTVMVPSDHDAAAEAVIAALALWSVASGTGLAGWLLLRMR
*. : . *
Rv1733c|M.tuberculosis_H37Rv LIRVRNASWQHDIDSLFCTQR-------
Mb1762c|M.bovis_AF2122/97 LIRVRNASWQHDIDSLFCTQR-------
MMAR_3501|M.marinum_M LDRVRDAQWDRELSCLQDDGGRTNRY--
MAV_1986|M.avium_104 LDRRRYAAWQRDFDRLVDQR--------
MSMEG_1127|M.smegmatis_MC2_155 CDRVRSAAWQRELDHLAGTDGFQYPTP-
TH_3263|M.thermoresistible__bu CDRIRTARWEHGLDSLEDAVWP------
Mflv_4998|M.gilvum_PYR-GCK LDHLRSQNWDRELDDLADNGGRSNNTT-
Mvan_1379|M.vanbaalenii_PYR-1 LNRMRFQAWDRELDDLADNGGRTNNNTP
: * *:: :. *