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MKAATQARIDDSPLAWLDAVQRQRHEAGLRRCLRPRPAVATELDLASNDYLGLSRHPAVIDGGVQALRIW GAGATGSRLVTGDTKLHQQFEAELAEFVGAAAGLLFSSGYTANLGAVVGLSGPGSLLVSDARSHASLVDA CRLSRARVVVTPHRDVDAVDAALRSRDEQRAVVVTDSVFSADGSLAPVRELLEVCRRHGALLLVDEAHGL GVRGGGRGLLYELGLAGAPDVVMTTTLSKALGSQGGVVLGPTPVRAHLIDAARPFIFDTGLAPAAVGAAR AALRVLQAEPWRPQAVLNHAGELARMCGVAAVPDSAMVSVILGEPESAVAAAAACLDAGVKVGCFRPPTV PAGTSRLRLTARASLNAGELELARRVLTDVLAVARR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv1569 | bioF1 | - | 100% (386) | 8-amino-7-oxononanoate synthase |
| M. tuberculosis H37Rv | Rv0032 | bioF2 | 7e-55 | 39.17% (337) | 8-amino-7-oxononanoate synthase BioF2 |
| M. tuberculosis H37Rv | Rv3340 | metC | 1e-05 | 25.32% (233) | O-acetylhomoserine aminocarboxypropyltransferase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1596 | bioF1 | 0.0 | 100.00% (386) | 8-amino-7-oxononanoate synthase |
| M. gilvum PYR-GCK | Mflv_3628 | - | 1e-162 | 79.41% (374) | 8-amino-7-oxononanoate synthase |
| M. leprae Br4923 | MLBr_01217 | bioF | 1e-171 | 80.05% (381) | 8-amino-7-oxononanoate synthase |
| M. abscessus ATCC 19977 | MAB_2687c | - | 1e-143 | 69.41% (376) | 8-amino-7-oxononanoate synthase |
| M. marinum M | MMAR_2384 | bioF1 | 0.0 | 84.06% (389) | 8-amino-7-oxononanoate synthase BioF1 |
| M. avium 104 | MAV_3205 | bioF | 1e-174 | 82.76% (377) | 8-amino-7-oxononanoate synthase |
| M. smegmatis MC2 155 | MSMEG_3189 | bioF | 1e-158 | 76.80% (375) | 8-amino-7-oxononanoate synthase |
| M. thermoresistible (build 8) | TH_2609 | - | 9e-13 | 80.95% (42) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_1560 | bioF1 | 1e-180 | 83.80% (389) | 8-amino-7-oxononanoate synthase |
| M. vanbaalenii PYR-1 | Mvan_2789 | - | 1e-160 | 77.66% (376) | 8-amino-7-oxononanoate synthase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3628|M.gilvum_PYR-GCK -----MTRAGLSPLAWLDEVETQRRAAGLRRSLRARPPVGTVLDLASNDY
Mvan_2789|M.vanbaalenii_PYR-1 -----MTRVSLSPLAWLDEVETQRRAAGLRRTVRTRPPVGAELDLASNDY
TH_2609|M.thermoresistible__bu --------------------------------------------------
MSMEG_3189|M.smegmatis_MC2_155 -----MTRAGLSPLAWLADIEQRRRAEGLRRELRVRPPVAAELDLASNDY
Rv1569|M.tuberculosis_H37Rv MKAATQARIDDSPLAWLDAVQRQRHEAGLRRCLRPRPAVATELDLASNDY
Mb1596|M.bovis_AF2122/97 MKAATQARIDDSPLAWLDAVQRQRHEAGLRRCLRPRPAVATELDLASNDY
MMAR_2384|M.marinum_M MGAPTQIPIETSPLAWLDAVERQRRDAGLRRSLRPRPPVGTELDLASNDY
MUL_1560|M.ulcerans_Agy99 MGAPTQIPIETSPLAWLDAVERQRRDAGLRRSLRPRPPVGTELDLASNDY
MLBr_01217|M.leprae_Br4923 ----MKVPIETSPLAWLEAVEQQRRGAGLRRSLRPRSAVATELDLASNDY
MAV_3205|M.avium_104 ----MKAPIEVSPLAWLDAVEQQRRAAGLRRSLRPRPPVATELDLASNDY
MAB_2687c|M.abscessus_ATCC_199 ----MPVVEASSPLAWLGEVERQREAAGLRRRLRTRSAAEPEIDLASNDY
Mflv_3628|M.gilvum_PYR-GCK LGLSQHPRVIDGGVAALRTWGAGATGSRLVTGNTELHEQFEDALASFVGA
Mvan_2789|M.vanbaalenii_PYR-1 LGLSQHPRVIDGGVSALRTWGAGSTGSRLVTGNTELHEAFEDVLAAFVGA
TH_2609|M.thermoresistible__bu --------------------------------------------------
MSMEG_3189|M.smegmatis_MC2_155 LGLSQHPDVLDGGVEALRTWGGGAGGSRLVTGNTELHEAFEHQLASFLGA
Rv1569|M.tuberculosis_H37Rv LGLSRHPAVIDGGVQALRIWGAGATGSRLVTGDTKLHQQFEAELAEFVGA
Mb1596|M.bovis_AF2122/97 LGLSRHPAVIDGGVQALRIWGAGATGSRLVTGDTKLHQQFEAELAEFVGA
MMAR_2384|M.marinum_M LGLSQHPDVIEGGVQALRIWGAGATGSRLVTGDTELHQQLEAELAEYVGA
MUL_1560|M.ulcerans_Agy99 LGLSQHPDVIEGGVQALRIWGAGATGSRLVTGDTELHQQLEAELAEYVGA
MLBr_01217|M.leprae_Br4923 LGLSQHPDVIDGGVAALRVWGAGATGSRLVTGDTILHHELECELAEFVGA
MAV_3205|M.avium_104 LGLSQHPDVIDGGVAALRLWGAGATGSRLVTGDTELHQQFESELADYVGA
MAB_2687c|M.abscessus_ATCC_199 LGLSRHPQVIEAGVEALRIWGAGSTGSRLVTGNTELHEELEQELATFMGT
Mflv_3628|M.gilvum_PYR-GCK DSALVFSSGYTANLGAVVALSGPGSLLVSDAYTHASLVDACRLSRARVVV
Mvan_2789|M.vanbaalenii_PYR-1 ESALVFSSGYTANLGAVVALSGPGSLLVSDANTHASLVDACRLSRARVVV
TH_2609|M.thermoresistible__bu --------------------------------------------------
MSMEG_3189|M.smegmatis_MC2_155 ESALVFSSGYTANLGALVALSGPGSLIVSDALSHASLVDACRLSRARVVV
Rv1569|M.tuberculosis_H37Rv AAGLLFSSGYTANLGAVVGLSGPGSLLVSDARSHASLVDACRLSRARVVV
Mb1596|M.bovis_AF2122/97 AAGLLFSSGYTANLGAVVGLSGPGSLLVSDARSHASLVDACRLSRARVVV
MMAR_2384|M.marinum_M AAGLLFSSGYTANLGAVVGLSGPGSLLVSDAYSHASLVDACRLSRARVVV
MUL_1560|M.ulcerans_Agy99 AAGLLFSSGYTANLGAVVGLSGPGSLLVSDAYSHASLVDACRLSRARVVV
MLBr_01217|M.leprae_Br4923 CVGLLFSSGYAANLGAVVGLSGPGSLIVSDAYSHASLVDACRLSRARVVV
MAV_3205|M.avium_104 ASGLLFSSGYAANLGAVVGLSGRGALVVSDAYSHASLVDACRLSRARVVV
MAB_2687c|M.abscessus_ATCC_199 ESALVFSSGYTANLGAVVALSGPGTLIVSDARTHASLIDACRLSRARVVV
Mflv_3628|M.gilvum_PYR-GCK TPHNDVAAVARALATRDEERAVVVTDSVFSADGDLAPLRELHDACRRHGA
Mvan_2789|M.vanbaalenii_PYR-1 TPHNDTAAVEQALATRSEARAVVVTDSVFSADGDLAPLRALHTACRKHGA
TH_2609|M.thermoresistible__bu --------------------------------------------------
MSMEG_3189|M.smegmatis_MC2_155 SPHRDVDAVDAALAARTEERAVVVTESVFSADGDLAPLRDLHAVCRRHGA
Rv1569|M.tuberculosis_H37Rv TPHRDVDAVDAALRSRDEQRAVVVTDSVFSADGSLAPVRELLEVCRRHGA
Mb1596|M.bovis_AF2122/97 TPHRDVDAVDAALRSRDEQRAVVVTDSVFSADGSLAPVRELLEVCRRHGA
MMAR_2384|M.marinum_M TPHRDVAAVDAALASRDEQRAMVITDSVFSADGTLAPLRELLAACRRHRA
MUL_1560|M.ulcerans_Agy99 TPHRDVAAVDAALASRDEQRAMVITDSVFSADGTLAPLRELLAACRRHRA
MLBr_01217|M.leprae_Br4923 TPHCDVDAVDTALRSCHEERAVVVTESVFSADGVLAPVSELHDVCRRHGA
MAV_3205|M.avium_104 TPHRDVDAVLAALADRDEERAVVITESVFSTDGALAPLRELHEVCRRHRA
MAB_2687c|M.abscessus_ATCC_199 TPYRDTQAVAAALAQRPEERALVLTDAVFSADGALAPLAELYGVCRRHGA
Mflv_3628|M.gilvum_PYR-GCK LMIVDEAHGLGVRGDRGRGLLDEVGLAGAPDVVMTTTLSKALGSQGGVVL
Mvan_2789|M.vanbaalenii_PYR-1 LLIVDEAHGLGVRGDGGRGLLDEVGLAGAPDLVMTTTLSKALGSQGGVVL
TH_2609|M.thermoresistible__bu --------------------------------------------------
MSMEG_3189|M.smegmatis_MC2_155 LLLVDEAHGLGVRGTRGQGLLHEVGLAGAPDIVMTTTLSKALGSQGGAVL
Rv1569|M.tuberculosis_H37Rv LLLVDEAHGLGVRG-GGRGLLYELGLAGAPDVVMTTTLSKALGSQGGVVL
Mb1596|M.bovis_AF2122/97 LLLVDEAHGLGVRG-GGRGLLYELGLAGAPDVVMTTTLSKALGSQGGVVL
MMAR_2384|M.marinum_M LLVIDEAHGLGVRG-GGRGLLHELGLAGAPDVVLTTTLSKALGSQGGAVL
MUL_1560|M.ulcerans_Agy99 LLVIDEAHGLGVRG-GGRGLLHELGLAGAPDVVLTTTLSKALGSQGGAVL
MLBr_01217|M.leprae_Br4923 LLLVDEAHGLGVRG-GGRGLVYEVGLAGAPDVVITTTMSKALGSQGGAVL
MAV_3205|M.avium_104 LLIVDEAHGLGVRG-GGRGLVFEAGLAGAPDVVMTTTLSKALGSQGGAVL
MAB_2687c|M.abscessus_ATCC_199 VLLVDEAHGLGVRGSGGRGLVAEMNLAGRDDLVVTVTLSKALGSQGGAVL
Mflv_3628|M.gilvum_PYR-GCK GPAAVRDHLIDAARPFIFDTGLAPAAVGAAHAALQVLVEEPWRAQRVLDH
Mvan_2789|M.vanbaalenii_PYR-1 GPAAVRAHLIDTARPFIFDTGLAPAAVGAAFAALQVLIDEPWRAQRVLDH
TH_2609|M.thermoresistible__bu --------------------------------------------------
MSMEG_3189|M.smegmatis_MC2_155 GPEAVRAHLIDTARSFIFDTGLAPAAVGAASAALRVLDAEPQRARAVLDR
Rv1569|M.tuberculosis_H37Rv GPTPVRAHLIDAARPFIFDTGLAPAAVGAARAALRVLQAEPWRPQAVLNH
Mb1596|M.bovis_AF2122/97 GPTPVRAHLIDAARPFIFDTGLAPAAVGAARAALRVLQAEPWRPQAVLNH
MMAR_2384|M.marinum_M GPAAVRAHLIDAARPFIFDTGLAPAAVGAARAALGVLKAEQWRPDAVLQN
MUL_1560|M.ulcerans_Agy99 GPAAVRAHLIDAARPFIFDTGLAPGAVGAARAALGVLKAEQWRPGAVLQN
MLBr_01217|M.leprae_Br4923 GSSAVRAHLINTARPFIFDTGLAPAAVGAARAALQILKAETWRPEAVLQH
MAV_3205|M.avium_104 GPAAVRAHLIDAARTFIFDTGLAPAAVGAARAALGVLRAEPWRVGAVLRH
MAB_2687c|M.abscessus_ATCC_199 GSAAVRAHLIDAARPFIFDTGLAPAAVGSALAALRLMIDEPARIRAVLAH
Mflv_3628|M.gilvum_PYR-GCK ATTLAQICGVADVPSSAVVSVILGEPEVALAAAMGCLERGVRVGCFRPPT
Mvan_2789|M.vanbaalenii_PYR-1 AATLASICDVTEVPSSAVVSVILGEPEVAFAAAAACLDRGVRVGCFRPPT
TH_2609|M.thermoresistible__bu ----------------------------------------VRVGCFRPPT
MSMEG_3189|M.smegmatis_MC2_155 AAELATIAGVTEAPVSAVVSVILGDPEIAVGAAAACLDRGVRVGCFRPPT
Rv1569|M.tuberculosis_H37Rv AGELARMCGVAAVPDSAMVSVILGEPESAVAAAAACLDAGVKVGCFRPPT
Mb1596|M.bovis_AF2122/97 AGELARMCGVAAVPDSAMVSVILGEPESAVAAAAACLDAGVKVGCFRPPT
MMAR_2384|M.marinum_M ARELADICDVPETPQSAVVSVLLGDPEVALAAAAACLDAGVKVGCFRPPT
MUL_1560|M.ulcerans_Agy99 ARELADICDVPETPQSAVVSVLLGDPEVALAAAAACLDAGVKVGCFRPPT
MLBr_01217|M.leprae_Br4923 ARTLAKICDLSELPQSAVVSVVLGDPEVALAAAIACLDAGVRVGCFRPPT
MAV_3205|M.avium_104 AGVLAEVCRVREVPQSAVVSVILGDPDVAVAAATACLDAGVRVGCFRPPT
MAB_2687c|M.abscessus_ATCC_199 AAALGQWCGVPDKPESAVVPVVLGDPTVAFNAARSCLEQGVRVGCFRPPS
*:*******:
Mflv_3628|M.gilvum_PYR-GCK VPAGTSRLRLTARASLSDDEMALAREVLTDVLSRA-----
Mvan_2789|M.vanbaalenii_PYR-1 VPAGTSRLRLTARASLSEDEMTLARRVLTEVLSPR-----
TH_2609|M.thermoresistible__bu VPAGTSRLRLTARASLTEDELALARRVFGEVLGARP----
MSMEG_3189|M.smegmatis_MC2_155 VPAGTSRLRLAARASLTDDEMALARQVLTDVLATARA---
Rv1569|M.tuberculosis_H37Rv VPAGTSRLRLTARASLNAGELELARRVLTDVL---AVARR
Mb1596|M.bovis_AF2122/97 VPAGTSRLRLTARASLNAGELELARRVLTDVL---AVARR
MMAR_2384|M.marinum_M VPAGTSRLRLTARASLSPDEMELARRVLTDVLLGPAAARR
MUL_1560|M.ulcerans_Agy99 VPAGTSRLRLTARASLSPDEMELARRVLTDVLLGPAAARR
MLBr_01217|M.leprae_Br4923 VPAGTSRLRLTAHASLDSAKLEVARRVLTDVLGGCCVARR
MAV_3205|M.avium_104 VPAGTSRLRLTARASLDDAELEVARRVLTDVLAGLG----
MAB_2687c|M.abscessus_ATCC_199 VPEGQSLLRLTARASLTEADMERVHEVLAGVLTLARR---
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