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MAAATGGLTPEQIIAVDGAHLWHPYSSIGREAVSPVVAVAAHGAWLTLIRDGQPIEVLDAMSSWWTAIHG HGHPALDQALTTQLRVMNHVMFGGLTHEPAARLAKLLVDITPAGLDTVFFSDSGSVSVEVAAKMALQYWR GRGLPGKRRLMTWRGGYHGDTFLAMSICDPHGGMHSLWTDVLAAQVFAPQVPRDYDPAYSAAFEAQLAQH AGELAAVVVEPVVQGAGGMRFHDPRYLHDLRDICRRYEVLLIFDEIATGFGRTGALFAADHAGVSPDIMC VGKALTGGYLSLAATLCTADVAHTISAGAAGALMHGPTFMANPLACAVSVASVELLLGQDWRTRITELAA GLTAGLDTARALPAVTDVRVCGAIGVIECDRPVDLAVATPAALDRGVWLRPFRNLVYAMPPYICTPAEIT QITSAMVEVARLVGSLP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv1568 | bioA | - | 100% (437) | adenosylmethionine--8-amino-7-oxononanoate transaminase |
| M. tuberculosis H37Rv | Rv3329 | - | 2e-34 | 30.21% (341) | hypothetical protein Rv3329 |
| M. tuberculosis H37Rv | Rv1655 | argD | 4e-30 | 29.37% (412) | acetylornithine aminotransferase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1595 | bioA | 0.0 | 100.00% (437) | adenosylmethionine--8-amino-7-oxononanoate transaminase |
| M. gilvum PYR-GCK | Mflv_3629 | - | 0.0 | 72.37% (427) | adenosylmethionine--8-amino-7-oxononanoate transaminase |
| M. leprae Br4923 | MLBr_01216 | bioA | 0.0 | 85.09% (436) | adenosylmethionine--8-amino-7-oxononanoate transaminase |
| M. abscessus ATCC 19977 | MAB_2688c | - | 1e-180 | 70.77% (431) | adenosylmethionine--8-amino-7-oxononanoate transaminase |
| M. marinum M | MMAR_2383 | bioA | 0.0 | 83.92% (429) | adenosylmethionine-8-amino-7-oxononanoate aminotransferase, |
| M. avium 104 | MAV_3206 | bioA | 0.0 | 82.07% (435) | adenosylmethionine--8-amino-7-oxononanoate transaminase |
| M. smegmatis MC2 155 | MSMEG_3188 | bioA | 0.0 | 75.12% (426) | adenosylmethionine--8-amino-7-oxononanoate transaminase |
| M. thermoresistible (build 8) | TH_4157 | - | 0.0 | 77.83% (433) | PUTATIVE adenosylmethionine-8-amino-7-oxononanoate |
| M. ulcerans Agy99 | MUL_1559 | bioA | 0.0 | 83.22% (429) | adenosylmethionine--8-amino-7-oxononanoate transaminase |
| M. vanbaalenii PYR-1 | Mvan_2788 | - | 0.0 | 74.71% (427) | adenosylmethionine--8-amino-7-oxononanoate transaminase |
CLUSTAL 2.0.9 multiple sequence alignment
Rv1568|M.tuberculosis_H37Rv -------MAAATG---GLTPEQIIAVDGAHLWHPYSSIGREA--VSPVVA
Mb1595|M.bovis_AF2122/97 -------MAAATG---GLTPEQIIAVDGAHLWHPYSSIGREA--VSPVVA
MLBr_01216|M.leprae_Br4923 -------MSGATS---GLTPEQIGAIDAAHLWHPYSTIGAATGVIPPVVA
MMAR_2383|M.marinum_M -------MSAADTSRGGLTPEQIGAIDAAHVWHPYSTIGTTA--APNLVV
MUL_1559|M.ulcerans_Agy99 -------MSAADTSRGGLTPEQIGAIDAANVWHPYSTIGTTA--APNLVV
MAV_3206|M.avium_104 -------MPAAKA---GLTPEQISAIDAAHLWHPYSTIGAES--VAPVVA
MSMEG_3188|M.smegmatis_MC2_155 --------------MADLTPAQISAVDAAHIWHPYSKIGADA--FPPVVA
TH_4157|M.thermoresistible__bu VRATPEEPSAGQAAPQKLTPEQIRSIDAAHIWHPYSAIGTAA--LAPVVA
Mflv_3629|M.gilvum_PYR-GCK --------------MSALRPAEISAIDAAHIWHPYSPIGDGA--LAPVVA
Mvan_2788|M.vanbaalenii_PYR-1 --------------MPALTPTEISAIDAAHIWHPYSPIGDTA--LAPTVA
MAB_2688c|M.abscessus_ATCC_199 --------------MPKLTPEEVEAVDAAHLWHPYSGIGIPAAAQRPLVV
* * :: ::*.*::***** ** : *.
Rv1568|M.tuberculosis_H37Rv VAAHGAWLTLIRDGQP----IEVLDAMSSWWTAIHGHGHPALDQALTTQL
Mb1595|M.bovis_AF2122/97 VAAHGAWLTLIRDGQP----IEVLDAMSSWWTAIHGHGHPALDQALTTQL
MLBr_01216|M.leprae_Br4923 VAAHGAWLTLIRDGKP----IEALDAMSSWWTAIHGHGHSVLDAALTTQL
MMAR_2383|M.marinum_M VSARGAWLTLIHDGQP----IEVLDAMSSWWTSVHGHGHPVLDAAVSAQV
MUL_1559|M.ulcerans_Agy99 VSARGAWLTLIHDGQP----IEVLDAMSSWWTSVHGHGHPVLDAAVSAQV
MAV_3206|M.avium_104 VGARGAWLTLIRDGAE----VRALDAMSSWWTAIHGHGHPVLDAALSDQL
MSMEG_3188|M.smegmatis_MC2_155 VGAKGAWLTVIDPSDG--ARIDVLDAMASWWTAVHGHGHPVLDAAISRQL
TH_4157|M.thermoresistible__bu VGARGAWLTVVAPDGGDDERLEVLDAMASWWTSIHGHGHPVLDRAITEQL
Mflv_3629|M.gilvum_PYR-GCK VGARGARLTLVHNGRE----VEVLDAMASWWTAVHGHGHPVLDAAITRQL
Mvan_2788|M.vanbaalenii_PYR-1 VGARGAWLTLVHQGRE----VEVLDAMASWWTAVHGHGHPVLDAAITRQL
MAB_2688c|M.abscessus_ATCC_199 TGASGPNITVVRDGRS----VEVLDGMSSWWSCIHGHGHPVLDRAVTDQL
..* *. :*:: . : .**.*:***:.:*****..** *:: *:
Rv1568|M.tuberculosis_H37Rv RVMNHVMFGGLTHEPAARLAKLLVDITPAGLDTVFFSDSGSVSVEVAAKM
Mb1595|M.bovis_AF2122/97 RVMNHVMFGGLTHEPAARLAKLLVDITPAGLDTVFFSDSGSVSVEVAAKM
MLBr_01216|M.leprae_Br4923 GAMNHVMFGGLTHEPAARLAQLLVDITPAGLETVFFSDSGSVSVQVAVKM
MMAR_2383|M.marinum_M GTMSHVMFGGLTHEPAARLAKLLVDITPAGLETVFFSDSGSVAVEVAVKM
MUL_1559|M.ulcerans_Agy99 GTMSHVMFGGLTHEPAARLAKLLVDITPAGLETVFFSDSGSVAVEVAVKM
MAV_3206|M.avium_104 AAMNHVMFGGLTHEPAARLAQLLVSITPAGLDTVFFSDSGSVSVEVAVKM
MSMEG_3188|M.smegmatis_MC2_155 STMNHVMFGGLTHEPAARLAQLLVELTPDGLDTVFFSDSGSVSVEVAVKM
TH_4157|M.thermoresistible__bu ATMNHVMFGGLTHEPAARLAQLLVDITPAGLDTVFFSDSGSVSIEVAVKM
Mflv_3629|M.gilvum_PYR-GCK ATMNHVMFGGLTHEPAARLAQLLVEVTPEALQTVFFSDSGSVSVEVAVKM
Mvan_2788|M.vanbaalenii_PYR-1 ATMNHVMFGGLTHEPAARLAQLLVEVTPEGLETVFFSDSGSVSVEVAVKM
MAB_2688c|M.abscessus_ATCC_199 ASMSHVMFGGLTHEPAARLAQLLVELTPAGLETVFFCDSGSVSVEVAIKM
*.****************:***.:** .*:****.*****:::** **
Rv1568|M.tuberculosis_H37Rv ALQYWRGRGLPGKRRLMTWRGGYHGDTFLAMSICDPHGGMHSLWT---DV
Mb1595|M.bovis_AF2122/97 ALQYWRGRGLPGKRRLMTWRGGYHGDTFLAMSICDPHGGMHSLWT---DV
MLBr_01216|M.leprae_Br4923 ALQYWRSRGQPAKRRLMTWRGGYHGDTLTPMSICDPDGGMHSLWT---DI
MMAR_2383|M.marinum_M ALQYWRSRGRPGKHRLMTWRGGYHGDTFTPMSVCDPEGGMHSLWT---DI
MUL_1559|M.ulcerans_Agy99 ALQYWRSRGRPGKHRLMTWRGGYHGDTFTPMSVCDPEGGMHSLWT---DI
MAV_3206|M.avium_104 ALQYWRSRHRPAKHRLMTWRGGYHGDTFTPMSVCDPEGGMHSLWT---DI
MSMEG_3188|M.smegmatis_MC2_155 ALQYWRSLGRGAKHRLMTWRGGYHGDTFTPMSVCDPDGGMHSLWT---DV
TH_4157|M.thermoresistible__bu ALQYWRSRGRPSKHRLMTWRGGYHGDTFTPMSVCDPDGGMHSLWT---DV
Mflv_3629|M.gilvum_PYR-GCK ALQFWRSGGHRAKSRLMTWRGGYHGDTFTPMSVCDPQGGMHELWSGRNSL
Mvan_2788|M.vanbaalenii_PYR-1 ALQFWRSTGRVRKSRLMTWRGGYHGDTFTPMSVCDPQGGMHELWTGENSL
MAB_2688c|M.abscessus_ATCC_199 ALQYWRSLGLPAKHRLMTWRGGYHGDTFAPMSVCDPEGGMHSLWT---DV
***:**. * *************: .**:***.****.**: .:
Rv1568|M.tuberculosis_H37Rv LAAQVFAPQVPRDYDPAYSAAFEAQLAQHAGELAAVVVEPVVQGAGGMRF
Mb1595|M.bovis_AF2122/97 LAAQVFAPQVPRDYDPAYSAAFEAQLAQHAGELAAVVVEPVVQGAGGMRF
MLBr_01216|M.leprae_Br4923 LARQVFAPQVPRDYDPAYSKAFETQLAQHTPELAAVVVEPVVQGAGGMRF
MMAR_2383|M.marinum_M LARQVFAPHVPHDYDPAYSAAFEAQLAQHAAELAAVVVEPVVQGAGGMRF
MUL_1559|M.ulcerans_Agy99 LARQVFAPHVPHDYDPAYSAAFEAQLAQHAAELAAVVVEPVVQGAGGMRF
MAV_3206|M.avium_104 LARQVFAPQVPRDYDPAYSAAFEAQLARHADELAAVIVEPVVQGAGGMRF
MSMEG_3188|M.smegmatis_MC2_155 LAAQEFAEAVPREYDPAYSAAFEKQLAANAGSLAAVIVEPVVQGAGGMRF
TH_4157|M.thermoresistible__bu LADQVFAPQVPRDYDPDYTAAFERQLAEHADELAAVIVEPVVQGAGGMRF
Mflv_3629|M.gilvum_PYR-GCK LADQVFADPVPAEHDAEYVRSLGDLLAVHAHELAAVIVEPVVQGAGGMRF
Mvan_2788|M.vanbaalenii_PYR-1 LADQVFAPPVPADYDPAYVAAFADQLARHADELAAVIVEPVVQGAGGMRF
MAB_2688c|M.abscessus_ATCC_199 LVEQIFADRVPGAYDGEYMRRFEAELTEHAAELAAVIVEPMVQGAGGMRF
*. * ** ** :* * : *: :: .****:***:*********
Rv1568|M.tuberculosis_H37Rv HDPRYLHDLRDICRRYEVLLIFDEIATGFGRTGALFAADHAGVSPDIMCV
Mb1595|M.bovis_AF2122/97 HDPRYLHDLRDICRRYEVLLIFDEIATGFGRTGALFAADHAGVSPDIMCV
MLBr_01216|M.leprae_Br4923 HDPRYLCDVRDICRRHDVLLIFDEIATGFGRTGELFAADHCGVSPDIMCV
MMAR_2383|M.marinum_M HDPRYLADLRDFCRRHEVLLIFDEIATGFGRTGELFAADHAGVSPDIMCV
MUL_1559|M.ulcerans_Agy99 HDPRYLADLRNFCRRHEVLLIFDEIATGFGHTGELFAADHAGVSPDIMCV
MAV_3206|M.avium_104 HDPRYLRDLREACTRHDVLLIFDEIATGFGRTGELFAADHARVSPDIMCV
MSMEG_3188|M.smegmatis_MC2_155 HDPRYLADLRAICDRHDVLLIFDEIATGFGRTGKLFAAEHAGVSPDIMCV
TH_4157|M.thermoresistible__bu HDPRYLSDLREICDRHRVLLIFDEIATGFGRTGALFAADHAGVTPDIMCV
Mflv_3629|M.gilvum_PYR-GCK HDPRYLRDLRRLCDEHAVLLIFDEIATGFGRTGAMFAADHAGVCPDIMCV
Mvan_2788|M.vanbaalenii_PYR-1 HDPRYLVDLRRLCDEHGVLLIFDEIATGFGRTGAMFAADHAGVSPDIMCV
MAB_2688c|M.abscessus_ATCC_199 HDPRYLAELRAICDRHGVLLIFDEIATGFGRTGELFAADHAGVSPDIMCV
****** ::* * .: *************:** :***:*. * ******
Rv1568|M.tuberculosis_H37Rv GKALTGGYLSLAATLCTADVAHTISAGAAGALMHGPTFMANPLACAVSVA
Mb1595|M.bovis_AF2122/97 GKALTGGYLSLAATLCTADVAHTISAGAAGALMHGPTFMANPLACAVSVA
MLBr_01216|M.leprae_Br4923 GKALTGGYLSLAATLCTTDIAHAISVGAAGALMHGPTFMANPLACAVSVA
MMAR_2383|M.marinum_M GKALTGGYLSLAATLCTTDIAHTISAGAAGALMHGPTFMANPLACAVSVA
MUL_1559|M.ulcerans_Agy99 GKALTGGYLSLAATLCTTDIAHTISAGAAGALMHGPTFMANPLACAVSVA
MAV_3206|M.avium_104 GKALTGGYLSLAATLCSTDIAQAISAGEAGALMHGPTFMANALACAVSVA
MSMEG_3188|M.smegmatis_MC2_155 GKALTGGYITLAATLCTARVAQTISSGEPGALMHGPTFMANALACAVGVA
TH_4157|M.thermoresistible__bu GKALTGGYLTLAATLCTSRVAHTISNGEPGALMHGPTFMANALACAVSVA
Mflv_3629|M.gilvum_PYR-GCK GKALTGGYLTLAATLCTRDVAATISSNEPGALMHGPTFMANALACAVSVA
Mvan_2788|M.vanbaalenii_PYR-1 GKALTGGYLTLAATLCTRVVADTISANPPGALMHGPTFMANALACAVSVA
MAB_2688c|M.abscessus_ATCC_199 GKAITGGYLTLAATLCTAKIAQTISDSPAGALMHGPTFMANPLACAVAVA
***:****::******: :* :** . .************.*****.**
Rv1568|M.tuberculosis_H37Rv SVELLLGQDWRTRITELAAGLTAGLDTARALPAVTDVRVCGAIGVIECDR
Mb1595|M.bovis_AF2122/97 SVELLLGQDWRTRITELAAGLTAGLDTARALPAVTDVRVCGAIGVIECDR
MLBr_01216|M.leprae_Br4923 SVEVLLGQDWRSRVAEISAGLTAGLEAAQGLPGVIDVRVCGAIGVIECDR
MMAR_2383|M.marinum_M SVELLLEQDWRGTVAGIASGLTTGLEPARALPGVTDVRVRGAIGVIECDR
MUL_1559|M.ulcerans_Agy99 SVELLLEQDWRGTVAGIASGLTTGLEPARALPGVTDVRVRGAIGVIECDR
MAV_3206|M.avium_104 SVEVLLGQDWRSRVAEISAGLAAGLEPARELPGVTDVRVRGAIGVIECDR
MSMEG_3188|M.smegmatis_MC2_155 AVELLIDSDWPARVAAIEEGLRSGLEPARALPGVADVRVLGAIGVIEMRE
TH_4157|M.thermoresistible__bu STELLLATDWRARVTALETRLRDGLAPARELRGVADVRVLGGIGVIEMAE
Mflv_3629|M.gilvum_PYR-GCK SVELLLASDWEAQVSSIEAGLRAGLEPARALPNVVDVRVLGAIGVIELDG
Mvan_2788|M.vanbaalenii_PYR-1 SVELLLATDWTARVRAIEDGLRCGLAQAASMPNVSDVRVLGAIGVIELDR
MAB_2688c|M.abscessus_ATCC_199 SIELLLSGDWKTRVARIAAGLREGLAPAADLEGVADVRVCGAIGVIDMEH
: *:*: ** : : * ** * : * **** *.****:
Rv1568|M.tuberculosis_H37Rv PVD---LAVATPAALDRGVWLRPFRNLVYAMPPYICTPAEITQITSAMVE
Mb1595|M.bovis_AF2122/97 PVD---LAVATPAALDRGVWLRPFRNLVYAMPPYICTPAEITQITSAMVE
MLBr_01216|M.leprae_Br4923 SVD---LAVATPAALDRRVWLRPFRNLVYAMPPYICPPAEIAQITSAMVE
MMAR_2383|M.marinum_M PVN---LSVATPVALEHGVWLRPFRNLVYAMPPYICAPDEIAQISSAMVE
MUL_1559|M.ulcerans_Agy99 PVN---LSVATPVALEHGVWLRPFRNLVYAMPPYICAPDEIAQISSAMVE
MAV_3206|M.avium_104 PVD---LAVATPAALDHGVWLRPFRNLIYAMPPYICPPDEIARIASAMVQ
MSMEG_3188|M.smegmatis_MC2_155 PVD---MPLATTTALAHGVWLRPFGKLIYAMPPFICTPEEVAQITAGMVG
TH_4157|M.thermoresistible__bu PVD---MAVATATALRNGVWLRPFRNLVYAMPPYICTPEEVDQIASAMVE
Mflv_3629|M.gilvum_PYR-GCK TVD---LGIATPVAIDHGVWLRPFRNLIYVMPPYICTPAEIATITSAMIE
Mvan_2788|M.vanbaalenii_PYR-1 PVD---LAVATPVAVEHGVWLRPFRNLVYVMPPYICTAAEVDQITSAMLA
MAB_2688c|M.abscessus_ATCC_199 PLGEQGMRIATGAALDEGVWLRPFRTLIYTMPPYICDEGEIRRITRAMVR
.:. : :** .*: . ****** .*:*.***:** *: *: .*:
Rv1568|M.tuberculosis_H37Rv VARLVGSLP---
Mb1595|M.bovis_AF2122/97 VARLVGSLP---
MLBr_01216|M.leprae_Br4923 VAGLVG------
MMAR_2383|M.marinum_M VARLVG------
MUL_1559|M.ulcerans_Agy99 VARLVG------
MAV_3206|M.avium_104 VAARLGSRRL--
MSMEG_3188|M.smegmatis_MC2_155 VARALT------
TH_4157|M.thermoresistible__bu VARALT------
Mflv_3629|M.gilvum_PYR-GCK VARALT------
Mvan_2788|M.vanbaalenii_PYR-1 VVRALT------
MAB_2688c|M.abscessus_ATCC_199 AATAVVAGRQVR
.. :