For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. thermoresistible (build 8) TH_4157 (-)

annotation: adenosylmethionine-8-amino-7-oxononanoate aminotransferase
coordinates: 3512945 - 3514291
length: 449

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_4157--100% (449)adenosylmethionine-8-amino-7-oxononanoate aminotransferase
M. thermoresistible (build 8)TH_1978-1e-3931.41% (382) PROBABLE AMINOTRANSFERASE
M. thermoresistible (build 8)TH_3529-3e-3130.77% (390) PUTATIVE aminotransferase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1595bioA0.077.83% (433) adenosylmethionine--8-amino-7-oxononanoate transaminase
M. gilvum PYR-GCKMflv_3629-0.075.12% (434) adenosylmethionine--8-amino-7-oxononanoate transaminase
M. tuberculosis H37RvRv1568bioA0.077.83% (433) adenosylmethionine--8-amino-7-oxononanoate transaminase
M. leprae Br4923MLBr_01216bioA0.075.52% (433) adenosylmethionine--8-amino-7-oxononanoate transaminase
M. abscessus ATCC 19977MAB_2688c-0.070.87% (436) adenosylmethionine--8-amino-7-oxononanoate transaminase
M. marinum MMMAR_2383bioA0.076.43% (437) adenosylmethionine-8-amino-7-oxononanoate aminotransferase,
M. avium 104MAV_3206bioA0.078.62% (435) adenosylmethionine--8-amino-7-oxononanoate transaminase
M. smegmatis MC2 155MSMEG_3188bioA0.080.28% (431) adenosylmethionine--8-amino-7-oxononanoate transaminase
M. ulcerans Agy99MUL_1559bioA0.075.97% (437) adenosylmethionine--8-amino-7-oxononanoate transaminase
M. vanbaalenii PYR-1Mvan_2788-0.079.03% (434) adenosylmethionine--8-amino-7-oxononanoate transaminase

CLUSTAL 2.0.9 multiple sequence alignment


Mb1595|M.bovis_AF2122/97            -------MAAATG---GLTPEQIIAVDGAHLWHPYSSIGREA--VSPVVA
Rv1568|M.tuberculosis_H37Rv         -------MAAATG---GLTPEQIIAVDGAHLWHPYSSIGREA--VSPVVA
MLBr_01216|M.leprae_Br4923          -------MSGATS---GLTPEQIGAIDAAHLWHPYSTIGAATGVIPPVVA
MMAR_2383|M.marinum_M               -------MSAADTSRGGLTPEQIGAIDAAHVWHPYSTIGTTA--APNLVV
MUL_1559|M.ulcerans_Agy99           -------MSAADTSRGGLTPEQIGAIDAANVWHPYSTIGTTA--APNLVV
MAV_3206|M.avium_104                -------MPAAKA---GLTPEQISAIDAAHLWHPYSTIGAES--VAPVVA
TH_4157|M.thermoresistible__bu      VRATPEEPSAGQAAPQKLTPEQIRSIDAAHIWHPYSAIGTAA--LAPVVA
MSMEG_3188|M.smegmatis_MC2_155      --------------MADLTPAQISAVDAAHIWHPYSKIGADA--FPPVVA
Mflv_3629|M.gilvum_PYR-GCK          --------------MSALRPAEISAIDAAHIWHPYSPIGDGA--LAPVVA
Mvan_2788|M.vanbaalenii_PYR-1       --------------MPALTPTEISAIDAAHIWHPYSPIGDTA--LAPTVA
MAB_2688c|M.abscessus_ATCC_199      --------------MPKLTPEEVEAVDAAHLWHPYSGIGIPAAAQRPLVV
                                                     * * :: ::*.*::***** **  :      *.

Mb1595|M.bovis_AF2122/97            VAAHGAWLTLIRDGQP----IEVLDAMSSWWTAIHGHGHPALDQALTTQL
Rv1568|M.tuberculosis_H37Rv         VAAHGAWLTLIRDGQP----IEVLDAMSSWWTAIHGHGHPALDQALTTQL
MLBr_01216|M.leprae_Br4923          VAAHGAWLTLIRDGKP----IEALDAMSSWWTAIHGHGHSVLDAALTTQL
MMAR_2383|M.marinum_M               VSARGAWLTLIHDGQP----IEVLDAMSSWWTSVHGHGHPVLDAAVSAQV
MUL_1559|M.ulcerans_Agy99           VSARGAWLTLIHDGQP----IEVLDAMSSWWTSVHGHGHPVLDAAVSAQV
MAV_3206|M.avium_104                VGARGAWLTLIRDGAE----VRALDAMSSWWTAIHGHGHPVLDAALSDQL
TH_4157|M.thermoresistible__bu      VGARGAWLTVVAPDGGDDERLEVLDAMASWWTSIHGHGHPVLDRAITEQL
MSMEG_3188|M.smegmatis_MC2_155      VGAKGAWLTVIDPSDG--ARIDVLDAMASWWTAVHGHGHPVLDAAISRQL
Mflv_3629|M.gilvum_PYR-GCK          VGARGARLTLVHNGRE----VEVLDAMASWWTAVHGHGHPVLDAAITRQL
Mvan_2788|M.vanbaalenii_PYR-1       VGARGAWLTLVHQGRE----VEVLDAMASWWTAVHGHGHPVLDAAITRQL
MAB_2688c|M.abscessus_ATCC_199      TGASGPNITVVRDGRS----VEVLDGMSSWWSCIHGHGHPVLDRAVTDQL
                                    ..* *. :*::  .      : .**.*:***:.:*****..** *:: *:

Mb1595|M.bovis_AF2122/97            RVMNHVMFGGLTHEPAARLAKLLVDITPAGLDTVFFSDSGSVSVEVAAKM
Rv1568|M.tuberculosis_H37Rv         RVMNHVMFGGLTHEPAARLAKLLVDITPAGLDTVFFSDSGSVSVEVAAKM
MLBr_01216|M.leprae_Br4923          GAMNHVMFGGLTHEPAARLAQLLVDITPAGLETVFFSDSGSVSVQVAVKM
MMAR_2383|M.marinum_M               GTMSHVMFGGLTHEPAARLAKLLVDITPAGLETVFFSDSGSVAVEVAVKM
MUL_1559|M.ulcerans_Agy99           GTMSHVMFGGLTHEPAARLAKLLVDITPAGLETVFFSDSGSVAVEVAVKM
MAV_3206|M.avium_104                AAMNHVMFGGLTHEPAARLAQLLVSITPAGLDTVFFSDSGSVSVEVAVKM
TH_4157|M.thermoresistible__bu      ATMNHVMFGGLTHEPAARLAQLLVDITPAGLDTVFFSDSGSVSIEVAVKM
MSMEG_3188|M.smegmatis_MC2_155      STMNHVMFGGLTHEPAARLAQLLVELTPDGLDTVFFSDSGSVSVEVAVKM
Mflv_3629|M.gilvum_PYR-GCK          ATMNHVMFGGLTHEPAARLAQLLVEVTPEALQTVFFSDSGSVSVEVAVKM
Mvan_2788|M.vanbaalenii_PYR-1       ATMNHVMFGGLTHEPAARLAQLLVEVTPEGLETVFFSDSGSVSVEVAVKM
MAB_2688c|M.abscessus_ATCC_199      ASMSHVMFGGLTHEPAARLAQLLVELTPAGLETVFFCDSGSVSVEVAIKM
                                      *.****************:***.:** .*:****.*****:::** **

Mb1595|M.bovis_AF2122/97            ALQYWRGRGLPGKRRLMTWRGGYHGDTFLAMSICDPHGGMHSLWT---DV
Rv1568|M.tuberculosis_H37Rv         ALQYWRGRGLPGKRRLMTWRGGYHGDTFLAMSICDPHGGMHSLWT---DV
MLBr_01216|M.leprae_Br4923          ALQYWRSRGQPAKRRLMTWRGGYHGDTLTPMSICDPDGGMHSLWT---DI
MMAR_2383|M.marinum_M               ALQYWRSRGRPGKHRLMTWRGGYHGDTFTPMSVCDPEGGMHSLWT---DI
MUL_1559|M.ulcerans_Agy99           ALQYWRSRGRPGKHRLMTWRGGYHGDTFTPMSVCDPEGGMHSLWT---DI
MAV_3206|M.avium_104                ALQYWRSRHRPAKHRLMTWRGGYHGDTFTPMSVCDPEGGMHSLWT---DI
TH_4157|M.thermoresistible__bu      ALQYWRSRGRPSKHRLMTWRGGYHGDTFTPMSVCDPDGGMHSLWT---DV
MSMEG_3188|M.smegmatis_MC2_155      ALQYWRSLGRGAKHRLMTWRGGYHGDTFTPMSVCDPDGGMHSLWT---DV
Mflv_3629|M.gilvum_PYR-GCK          ALQFWRSGGHRAKSRLMTWRGGYHGDTFTPMSVCDPQGGMHELWSGRNSL
Mvan_2788|M.vanbaalenii_PYR-1       ALQFWRSTGRVRKSRLMTWRGGYHGDTFTPMSVCDPQGGMHELWTGENSL
MAB_2688c|M.abscessus_ATCC_199      ALQYWRSLGLPAKHRLMTWRGGYHGDTFAPMSVCDPEGGMHSLWT---DV
                                    ***:**.     * *************: .**:***.****.**:   .:

Mb1595|M.bovis_AF2122/97            LAAQVFAPQVPRDYDPAYSAAFEAQLAQHAGELAAVVVEPVVQGAGGMRF
Rv1568|M.tuberculosis_H37Rv         LAAQVFAPQVPRDYDPAYSAAFEAQLAQHAGELAAVVVEPVVQGAGGMRF
MLBr_01216|M.leprae_Br4923          LARQVFAPQVPRDYDPAYSKAFETQLAQHTPELAAVVVEPVVQGAGGMRF
MMAR_2383|M.marinum_M               LARQVFAPHVPHDYDPAYSAAFEAQLAQHAAELAAVVVEPVVQGAGGMRF
MUL_1559|M.ulcerans_Agy99           LARQVFAPHVPHDYDPAYSAAFEAQLAQHAAELAAVVVEPVVQGAGGMRF
MAV_3206|M.avium_104                LARQVFAPQVPRDYDPAYSAAFEAQLARHADELAAVIVEPVVQGAGGMRF
TH_4157|M.thermoresistible__bu      LADQVFAPQVPRDYDPDYTAAFERQLAEHADELAAVIVEPVVQGAGGMRF
MSMEG_3188|M.smegmatis_MC2_155      LAAQEFAEAVPREYDPAYSAAFEKQLAANAGSLAAVIVEPVVQGAGGMRF
Mflv_3629|M.gilvum_PYR-GCK          LADQVFADPVPAEHDAEYVRSLGDLLAVHAHELAAVIVEPVVQGAGGMRF
Mvan_2788|M.vanbaalenii_PYR-1       LADQVFAPPVPADYDPAYVAAFADQLARHADELAAVIVEPVVQGAGGMRF
MAB_2688c|M.abscessus_ATCC_199      LVEQIFADRVPGAYDGEYMRRFEAELTEHAAELAAVIVEPMVQGAGGMRF
                                    *. * **  **  :*  *   :   *: :: .****:***:*********

Mb1595|M.bovis_AF2122/97            HDPRYLHDLRDICRRYEVLLIFDEIATGFGRTGALFAADHAGVSPDIMCV
Rv1568|M.tuberculosis_H37Rv         HDPRYLHDLRDICRRYEVLLIFDEIATGFGRTGALFAADHAGVSPDIMCV
MLBr_01216|M.leprae_Br4923          HDPRYLCDVRDICRRHDVLLIFDEIATGFGRTGELFAADHCGVSPDIMCV
MMAR_2383|M.marinum_M               HDPRYLADLRDFCRRHEVLLIFDEIATGFGRTGELFAADHAGVSPDIMCV
MUL_1559|M.ulcerans_Agy99           HDPRYLADLRNFCRRHEVLLIFDEIATGFGHTGELFAADHAGVSPDIMCV
MAV_3206|M.avium_104                HDPRYLRDLREACTRHDVLLIFDEIATGFGRTGELFAADHARVSPDIMCV
TH_4157|M.thermoresistible__bu      HDPRYLSDLREICDRHRVLLIFDEIATGFGRTGALFAADHAGVTPDIMCV
MSMEG_3188|M.smegmatis_MC2_155      HDPRYLADLRAICDRHDVLLIFDEIATGFGRTGKLFAAEHAGVSPDIMCV
Mflv_3629|M.gilvum_PYR-GCK          HDPRYLRDLRRLCDEHAVLLIFDEIATGFGRTGAMFAADHAGVCPDIMCV
Mvan_2788|M.vanbaalenii_PYR-1       HDPRYLVDLRRLCDEHGVLLIFDEIATGFGRTGAMFAADHAGVSPDIMCV
MAB_2688c|M.abscessus_ATCC_199      HDPRYLAELRAICDRHGVLLIFDEIATGFGRTGELFAADHAGVSPDIMCV
                                    ****** ::*  * .: *************:** :***:*. * ******

Mb1595|M.bovis_AF2122/97            GKALTGGYLSLAATLCTADVAHTISAGAAGALMHGPTFMANPLACAVSVA
Rv1568|M.tuberculosis_H37Rv         GKALTGGYLSLAATLCTADVAHTISAGAAGALMHGPTFMANPLACAVSVA
MLBr_01216|M.leprae_Br4923          GKALTGGYLSLAATLCTTDIAHAISVGAAGALMHGPTFMANPLACAVSVA
MMAR_2383|M.marinum_M               GKALTGGYLSLAATLCTTDIAHTISAGAAGALMHGPTFMANPLACAVSVA
MUL_1559|M.ulcerans_Agy99           GKALTGGYLSLAATLCTTDIAHTISAGAAGALMHGPTFMANPLACAVSVA
MAV_3206|M.avium_104                GKALTGGYLSLAATLCSTDIAQAISAGEAGALMHGPTFMANALACAVSVA
TH_4157|M.thermoresistible__bu      GKALTGGYLTLAATLCTSRVAHTISNGEPGALMHGPTFMANALACAVSVA
MSMEG_3188|M.smegmatis_MC2_155      GKALTGGYITLAATLCTARVAQTISSGEPGALMHGPTFMANALACAVGVA
Mflv_3629|M.gilvum_PYR-GCK          GKALTGGYLTLAATLCTRDVAATISSNEPGALMHGPTFMANALACAVSVA
Mvan_2788|M.vanbaalenii_PYR-1       GKALTGGYLTLAATLCTRVVADTISANPPGALMHGPTFMANALACAVSVA
MAB_2688c|M.abscessus_ATCC_199      GKAITGGYLTLAATLCTAKIAQTISDSPAGALMHGPTFMANPLACAVAVA
                                    ***:****::******:  :* :** . .************.*****.**

Mb1595|M.bovis_AF2122/97            SVELLLGQDWRTRITELAAGLTAGLDTARALPAVTDVRVCGAIGVIECDR
Rv1568|M.tuberculosis_H37Rv         SVELLLGQDWRTRITELAAGLTAGLDTARALPAVTDVRVCGAIGVIECDR
MLBr_01216|M.leprae_Br4923          SVEVLLGQDWRSRVAEISAGLTAGLEAAQGLPGVIDVRVCGAIGVIECDR
MMAR_2383|M.marinum_M               SVELLLEQDWRGTVAGIASGLTTGLEPARALPGVTDVRVRGAIGVIECDR
MUL_1559|M.ulcerans_Agy99           SVELLLEQDWRGTVAGIASGLTTGLEPARALPGVTDVRVRGAIGVIECDR
MAV_3206|M.avium_104                SVEVLLGQDWRSRVAEISAGLAAGLEPARELPGVTDVRVRGAIGVIECDR
TH_4157|M.thermoresistible__bu      STELLLATDWRARVTALETRLRDGLAPARELRGVADVRVLGGIGVIEMAE
MSMEG_3188|M.smegmatis_MC2_155      AVELLIDSDWPARVAAIEEGLRSGLEPARALPGVADVRVLGAIGVIEMRE
Mflv_3629|M.gilvum_PYR-GCK          SVELLLASDWEAQVSSIEAGLRAGLEPARALPNVVDVRVLGAIGVIELDG
Mvan_2788|M.vanbaalenii_PYR-1       SVELLLATDWTARVRAIEDGLRCGLAQAASMPNVSDVRVLGAIGVIELDR
MAB_2688c|M.abscessus_ATCC_199      SIELLLSGDWKTRVARIAAGLREGLAPAADLEGVADVRVCGAIGVIDMEH
                                    : *:*:  **   :  :   *  **  *  :  * **** *.****:   

Mb1595|M.bovis_AF2122/97            PVD---LAVATPAALDRGVWLRPFRNLVYAMPPYICTPAEITQITSAMVE
Rv1568|M.tuberculosis_H37Rv         PVD---LAVATPAALDRGVWLRPFRNLVYAMPPYICTPAEITQITSAMVE
MLBr_01216|M.leprae_Br4923          SVD---LAVATPAALDRRVWLRPFRNLVYAMPPYICPPAEIAQITSAMVE
MMAR_2383|M.marinum_M               PVN---LSVATPVALEHGVWLRPFRNLVYAMPPYICAPDEIAQISSAMVE
MUL_1559|M.ulcerans_Agy99           PVN---LSVATPVALEHGVWLRPFRNLVYAMPPYICAPDEIAQISSAMVE
MAV_3206|M.avium_104                PVD---LAVATPAALDHGVWLRPFRNLIYAMPPYICPPDEIARIASAMVQ
TH_4157|M.thermoresistible__bu      PVD---MAVATATALRNGVWLRPFRNLVYAMPPYICTPEEVDQIASAMVE
MSMEG_3188|M.smegmatis_MC2_155      PVD---MPLATTTALAHGVWLRPFGKLIYAMPPFICTPEEVAQITAGMVG
Mflv_3629|M.gilvum_PYR-GCK          TVD---LGIATPVAIDHGVWLRPFRNLIYVMPPYICTPAEIATITSAMIE
Mvan_2788|M.vanbaalenii_PYR-1       PVD---LAVATPVAVEHGVWLRPFRNLVYVMPPYICTAAEVDQITSAMLA
MAB_2688c|M.abscessus_ATCC_199      PLGEQGMRIATGAALDEGVWLRPFRTLIYTMPPYICDEGEIRRITRAMVR
                                    .:.   : :** .*: . ****** .*:*.***:**   *:  *: .*: 

Mb1595|M.bovis_AF2122/97            VARLVGSLP---
Rv1568|M.tuberculosis_H37Rv         VARLVGSLP---
MLBr_01216|M.leprae_Br4923          VAGLVG------
MMAR_2383|M.marinum_M               VARLVG------
MUL_1559|M.ulcerans_Agy99           VARLVG------
MAV_3206|M.avium_104                VAARLGSRRL--
TH_4157|M.thermoresistible__bu      VARALT------
MSMEG_3188|M.smegmatis_MC2_155      VARALT------
Mflv_3629|M.gilvum_PYR-GCK          VARALT------
Mvan_2788|M.vanbaalenii_PYR-1       VVRALT------
MAB_2688c|M.abscessus_ATCC_199      AATAVVAGRQVR
                                    ..  :