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KRIYAFAIGLVMMAAPMAAAPGIAAADPSVRPVDYQQATDVVVARGLSQRGVPFSWAGGGITGPSRGKGT GIYTVGFDASGLIQYAYAGAGIKLPRSSGEMYKVGQKVLPQQARKADLLFYGPEGTQSVAMYLGNGQMLE VGDVVQVSPVRTTDMMPYLVRIIGASQAPLQQTPLPQTPLRQAPLQQVPTQQVPTQQAPLQQAPAQQLPT QQAPLQAPTRQAPTQQVPLQQLPTQQSPVQQAPTQLVPLQPAPATTAR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_2381 | - | - | 100% (259) | inv protein |
| M. marinum M | MMAR_2285 | iipB | 2e-38 | 48.80% (166) | invasion and intracellular persistence protein, IipB |
| M. marinum M | MMAR_2284 | iipA | 1e-36 | 51.91% (131) | invasion and intracellular persistence protein, IipA |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1593c | - | 9e-98 | 78.04% (214) | inv protein |
| M. gilvum PYR-GCK | Mflv_3253 | - | 1e-43 | 46.26% (214) | NLP/P60 protein |
| M. tuberculosis H37Rv | Rv1566c | - | 9e-98 | 78.04% (214) | inv protein |
| M. leprae Br4923 | MLBr_01214 | - | 3e-71 | 60.27% (224) | putative secreted p60-family protein |
| M. abscessus ATCC 19977 | MAB_2474 | - | 8e-42 | 49.20% (187) | hypothetical protein MAB_2474 |
| M. avium 104 | MAV_3208 | - | 1e-109 | 69.20% (289) | NlpC/P60 family protein |
| M. smegmatis MC2 155 | MSMEG_3477 | - | 5e-47 | 47.95% (219) | inv protein |
| M. thermoresistible (build 8) | TH_0420 | - | 2e-45 | 54.64% (183) | Possible inv protein |
| M. ulcerans Agy99 | MUL_1557 | - | 1e-147 | 100.00% (259) | inv protein |
| M. vanbaalenii PYR-1 | Mvan_2970 | - | 3e-45 | 48.58% (212) | NLP/P60 protein |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_2381|M.marinum_M MKRIY---AFAIGLVMMAAPMA----AAPGIAAADPSVRPVDYQQATDVV
MUL_1557|M.ulcerans_Agy99 MKRIY---AFAIGLVMMAAPMA----AAPGIAAADPSVRPVDYQQATDVV
MAV_3208|M.avium_104 MKRIY---AFAIGLALLGAPAAP--MVVPAVATADPGVRAMDYQQATDVV
Mb1593c|M.bovis_AF2122/97 MKRSMKSGSFAIGLAMMLAPMV----AAPGLAAADPATRPVDYQQITDVV
Rv1566c|M.tuberculosis_H37Rv MKRSMKSGSFAIGLAMMLAPMV----AAPGLAAADPATRPVDYQQITDVV
MLBr_01214|M.leprae_Br4923 MNRIY---TFVTGLAMLVTSIL----TCS-LAYADSGTRTADYQQTIDTV
Mflv_3253|M.gilvum_PYR-GCK MRRLY---VFVIALALVLATPGVAVLATPGVATALP-GRSATNQKAVEAV
Mvan_2970|M.vanbaalenii_PYR-1 MRRLL---VFVIGLALLLATP--------GLATAQP-ARSATNQKAVEAV
MSMEG_3477|M.smegmatis_MC2_155 MRRAY---AVLVSLAVSTAVLLG----IPGIAAAAPYDRPAGNQRFVEIV
TH_0420|M.thermoresistible__bu MRRVF---ALVISLAVLVATP--------AVAVAYP-SYPTRNHQAVKVV
MAB_2474|M.abscessus_ATCC_1997 MKSTY---AVLLGIALLLVTP--------GLASADVPRSPVDRQQAINAV
*. . .:.: . :* * . :: . *
MMAR_2381|M.marinum_M VARGLSQRGVPFSWAGGGITGPSRGK------------------------
MUL_1557|M.ulcerans_Agy99 VARGLSQRGVPFSWAGGGITGPSRGK------------------------
MAV_3208|M.avium_104 IARGLSQRGVPFSWAGGGINGPTRGT------------------------
Mb1593c|M.bovis_AF2122/97 IARGLSQRGVPFSWAGGGISGPTRGT------------------------
Rv1566c|M.tuberculosis_H37Rv IARGLSQRGVPFSWAGGGISGPTRGT------------------------
MLBr_01214|M.leprae_Br4923 VQRALAQRGVPFSWAGGGVSGPTRGT------------------------
Mflv_3253|M.gilvum_PYR-GCK IARALSQRGVPFAYGGGGASGPSKGTVALPEAAPAVPDQA----EIDAQA
Mvan_2970|M.vanbaalenii_PYR-1 IARALSQRGVPFAYGGGGASGPSKGTVAVPEAEPALPDQA----EVDAQS
MSMEG_3477|M.smegmatis_MC2_155 IARALSQRGVPFTYGGGDVNGPTRGVPREIPPAAAVPTGAYPGLAPAATP
TH_0420|M.thermoresistible__bu LERALSQQGVPFSYGGGDASGPTRGS------------------GTAANA
MAB_2474|M.abscessus_ATCC_1997 IARGLSQRGVPFTYGGGNTDGPTTST--------------------DTAP
: *.*:*:****::.**. **: .
MMAR_2381|M.marinum_M ------------------------------GTGIYTVGFDASGLIQYAYA
MUL_1557|M.ulcerans_Agy99 ------------------------------GTGIYTVGFDASGLIQYAYA
MAV_3208|M.avium_104 ------------------------------GTGANTVGFDASGLMQYAYA
Mb1593c|M.bovis_AF2122/97 ------------------------------GTGINTVGFDASGLIQYAYA
Rv1566c|M.tuberculosis_H37Rv ------------------------------GTGINTVGFDASGLIQYAYA
MLBr_01214|M.leprae_Br4923 ------------------------------GTGSNTVGFDASGLIQYAYA
Mflv_3253|M.gilvum_PYR-GCK LTESPGLNLPGVTPNVAVPTLPAP-----PAPRVEVVGFDASGLMVYAFS
Mvan_2970|M.vanbaalenii_PYR-1 LDLAPGLNVPSVTPNVAAP-IPAPTPA--PAPRIEVVGFDASGLMVYAYA
MSMEG_3477|M.smegmatis_MC2_155 EALTPGLNTPAVTPGLSAPAITPGLVAPVAAPAPDVVGFDASGLIVYAFA
TH_0420|M.thermoresistible__bu IGLDPAGRVVGLDP------------------AQNIVGFDASGLMVYAFA
MAB_2474|M.abscessus_ATCC_1997 AAPEANTSLLGLIPAPVA------------APTPKVPGFDASGLMVYSYA
*******: *:::
MMAR_2381|M.marinum_M GAGIKLPRSSGEMYKVGQKVLPQQARKADLLFYGPEGTQSVAMYLGNGQM
MUL_1557|M.ulcerans_Agy99 GAGIKLPRSSGEMYKVGQKVLPQQARKADLLFYGPEGTQSVAMYLGNGQM
MAV_3208|M.avium_104 GAGIKLPRSSGAMYRVGQKILPQQARKGDLIFYGPEGTQSVAMYLGNNQM
Mb1593c|M.bovis_AF2122/97 GAGLKLPRSSGQMYKVGQKVLPQQARKGDLIFYGPEGTQSVALYLGKGQM
Rv1566c|M.tuberculosis_H37Rv GAGLKLPRSSGQMYKVGQKVLPQQARKGDLIFYGPEGTQSVALYLGKGQM
MLBr_01214|M.leprae_Br4923 GAGLKLPRSSGEMYKVGQKVLPRHARRGDLIFYGPEGTESVTLYLGDEKM
Mflv_3253|M.gilvum_PYR-GCK GVGVKLPRSSGEMYKVGQKVAPALAMPGDLIFYGPEGTQSVALFIGNGQM
Mvan_2970|M.vanbaalenii_PYR-1 GVGVKLPRSSGEMYKVGQKVLPAQALPGDLIFYGPEGTQSVALFIGNGQM
MSMEG_3477|M.smegmatis_MC2_155 GAGVKMPRSSGEQYKVGQKVLPSQALPGDLIFYGPEGTQSVALFVGNGQM
TH_0420|M.thermoresistible__bu GVGIKLPRSSGEQYKVGYKVTPDQALPGDLIFYGPEGTQSVALFLGNGQM
MAB_2474|M.abscessus_ATCC_1997 AAGIKLPRRSGDQYNVGRKILPAQALPGDLIFYGPNGSQSVTMFLGNNLM
..*:*:** ** *.** *: * * .**:****:*::**::::*. *
MMAR_2381|M.marinum_M LEVGD-VVQVSPVRTTDMMPYLVRIIG------------------ASQAP
MUL_1557|M.ulcerans_Agy99 LEVGD-VVQVSPVRTTDMMPYLVRIIG------------------ASQAP
MAV_3208|M.avium_104 LEVGD-VVQVSPVRTAGMAPYMVRVLGTTAPTQQVPQQAPLQQTPAQQAP
Mb1593c|M.bovis_AF2122/97 LEVGD-VVQVSPVRTNGMTPYLVRVLG-----------------------
Rv1566c|M.tuberculosis_H37Rv LEVGD-VVQVSPVRTNGMTPYLVRVLG-----------------------
MLBr_01214|M.leprae_Br4923 VEVGE-VVQVSPVRSNGMAPYLVRVLG-----------------------
Mflv_3253|M.gilvum_PYR-GCK VETTDTGVAVSPVRTNGMSPYLVRIIA-----------------------
Mvan_2970|M.vanbaalenii_PYR-1 VETTDAGVAVSSVRTKDMTPYLVRIIA-----------------------
MSMEG_3477|M.smegmatis_MC2_155 VETTDSGVQVSPVRTENMTPYLVRIIA-----------------------
TH_0420|M.thermoresistible__bu IEATDPVVRVSPVRFDNMAPYLSRIIP-----------------------
MAB_2474|M.abscessus_ATCC_1997 LEASEPAVQVSQVRFNDMAPYLVRVIE-----------------------
:*. : * ** ** .* **: *::
MMAR_2381|M.marinum_M LQQTP-----LPQTP-----LRQAPLQQVPTQQVPTQQAPLQQAPAQQLP
MUL_1557|M.ulcerans_Agy99 LQQTP-----LPQTP-----LRQAPLQQVPTQQVPTQQAPLQQAPAQQLP
MAV_3208|M.avium_104 LQQTPGQQAPLQQTPGQQLPTQQAPLQQVPGQQVPAQQVPAQQVPGQQLP
Mb1593c|M.bovis_AF2122/97 ------------------------------TQPTPVQQAPVQPAP-----
Rv1566c|M.tuberculosis_H37Rv ------------------------------TQPTPVQQAPVQPAP-----
MLBr_01214|M.leprae_Br4923 ------------------------------TQPTSVPQAPLQQVP-----
Mflv_3253|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2970|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_3477|M.smegmatis_MC2_155 --------------------------------------------------
TH_0420|M.thermoresistible__bu --------------------------------------------------
MAB_2474|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_2381|M.marinum_M TQQAPLQAPTRQAPTQQVPLQQLPTQQSPVQQAPTQLVPLQPAPATTAR-
MUL_1557|M.ulcerans_Agy99 TQQAPLQAPTRQAPTQQVPLQQLPTQQSPVQQAPTQLVPLQPAPATTAR-
MAV_3208|M.avium_104 TQQAPQQAPLQLAPTQQAPLQQLPTQQSPLQQLPVQQSPLQPAGAGLTR-
Mb1593c|M.bovis_AF2122/97 ----VQQAPVQQAPVQQAPVQQAPVQQAPVQQAPVQQAPVQPPPFGTARS
Rv1566c|M.tuberculosis_H37Rv ----VQQAPVQQAPVQQAPVQQAPVQQAPVQQAPVQQAPVQPPPFGTARS
MLBr_01214|M.leprae_Br4923 ----TLPAP-----------QQTPTHRAPLQHMPLQ-VPVRPVPVSTAR-
Mflv_3253|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2970|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_3477|M.smegmatis_MC2_155 --------------------------------------------------
TH_0420|M.thermoresistible__bu --------------------------------------------------
MAB_2474|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_2381|M.marinum_M -
MUL_1557|M.ulcerans_Agy99 -
MAV_3208|M.avium_104 -
Mb1593c|M.bovis_AF2122/97 R
Rv1566c|M.tuberculosis_H37Rv R
MLBr_01214|M.leprae_Br4923 -
Mflv_3253|M.gilvum_PYR-GCK -
Mvan_2970|M.vanbaalenii_PYR-1 -
MSMEG_3477|M.smegmatis_MC2_155 -
TH_0420|M.thermoresistible__bu -
MAB_2474|M.abscessus_ATCC_1997 -