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VSSVADGLLALSVRSAGVPLRELALVGLTAAIITYFATGPVRVLATRLGAVAYPRERDVHVTPTPRMGGL AMFLGVLAAVFLASQLPALTRGFVYSTGMPAVLVAGAVIMGIGLIDDRWGLDALTKFAGQITAASVLVTM GVAWSVLYIPLGGVGTIVLDQASSILLTLALTVSIVNAMNFVDGLDGLAAGLGLITALAICTFSVGLLRD HGGDVLFYPPAVISVVLAGACLGFLPHNFHRAKIFMGDSGSMLVGLMLAAASTTAAGPISQNAYGARDVF ALLSPFLLVVAVMFVPMLDLLLAIVRRTRAGRSAFSPDKMHLHHRLLQIGHSHRRVVLLIYLWVGIVAFG AASTIFVDPRHTAAVMLGALVVAGVVTAIPLLRRRDDYYDPD*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_3962 | rfe | - | 100% (393) | undecapaprenyl-phosphate alpha-N- acetylglucosaminyltransferase Rfe |
| M. ulcerans Agy99 | MUL_3504 | mraY | 1e-19 | 28.30% (311) | phospho-N-acetylmuramoyl-pentapeptide-transferase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1334 | rfe | 0.0 | 93.88% (392) | putative undecapaprenyl-phosphate |
| M. gilvum PYR-GCK | Mflv_2310 | - | 0.0 | 84.68% (385) | glycosyl transferase family protein |
| M. tuberculosis H37Rv | Rv1302 | rfe | 0.0 | 94.13% (392) | undecapaprenyl-phosphate |
| M. leprae Br4923 | MLBr_01137 | - | 0.0 | 91.49% (388) | putative glycosyltransferase |
| M. abscessus ATCC 19977 | MAB_1445 | - | 1e-180 | 82.32% (379) | putative undecaprenyl-phosphate |
| M. marinum M | MMAR_4095 | rfe | 0.0 | 100.00% (392) | undecapaprenyl-phosphate alpha-N- |
| M. avium 104 | MAV_1519 | - | 0.0 | 93.37% (392) | glycosyl transferase, group 4 family protein |
| M. smegmatis MC2 155 | MSMEG_4947 | - | 0.0 | 89.21% (380) | glycosyl trasferase |
| M. thermoresistible (build 8) | TH_1564 | rfe | 0.0 | 87.18% (390) | PROBABLE UNDECAPAPRENYL-PHOSPHATE |
| M. vanbaalenii PYR-1 | Mvan_4336 | - | 0.0 | 86.20% (384) | glycosyl transferase family protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2310|M.gilvum_PYR-GCK -MDLASATITATRAG----ESLLALDERGAGVPLRELALVGLTAAIITYL
Mvan_4336|M.vanbaalenii_PYR-1 -MHLASATMTIAQAG----ESVMALSDRGAGVPLRELALVGLTAAIITYL
MSMEG_4947|M.smegmatis_MC2_155 MLQYGAPVITATRETGMDSQVVLALSDTGAGVPLRELALVGLTAAIITYF
TH_1564|M.thermoresistible__bu -VQYGSAVVTAT-------DSILALSERGAGVPLRELALVGLTATIITYF
MUL_3962|M.ulcerans_Agy99 -----------MVSS--VADGLLALSVRSAGVPLRELALVGLTAAIITYF
MMAR_4095|M.marinum_M ------------MSS--VADGLLALSVRSAGVPLRELALVGLTAAIITYF
Mb1334|M.bovis_AF2122/97 -MQYGL-EVSSDVAG--VAGGLLALSYRGAGVPLRELALVGLTAAIITYF
Rv1302|M.tuberculosis_H37Rv -MQYGL-EVSSDVAG--VAGGLLALSYRGAGVPLRELALVGLTAAIITYF
MAV_1519|M.avium_104 -MSSTVSLVSSDVTD--LAGGLLALSDRGAGVPLRELALVGLTAAIITYF
MLBr_01137|M.leprae_Br4923 -MVQYVREMSSDLAT--FASGLLALFERSAGVPLRELALVGLTAAIITYF
MAB_1445|M.abscessus_ATCC_1997 ------------------MSELLALADRGAGVPLRELALVGLTAAITTFF
::** .***************:* *::
Mflv_2310|M.gilvum_PYR-GCK ATGWVRVLATRWGAVAYPRERDVHLQPIARMGGLAMYIGVVAAVLLASQL
Mvan_4336|M.vanbaalenii_PYR-1 ATGWVRVLATRWGAVAYPRERDVHVAPTPRMGGLAMYLGVVAAVLLASQL
MSMEG_4947|M.smegmatis_MC2_155 ATGWVRVLAIRFGAVAYPRERDVHVQPTPRMGGLAMYIGVASAVLLASQL
TH_1564|M.thermoresistible__bu ATGWVRVLAIRLGAVAYPRERDVHVRPTPRMGGLAMYIGVAAAVLLASQL
MUL_3962|M.ulcerans_Agy99 ATGPVRVLATRLGAVAYPRERDVHVTPTPRMGGLAMFLGVLAAVFLASQL
MMAR_4095|M.marinum_M ATGPVRVLATRLGAVAYPRERDVHVTPTPRMGGLAMFLGVLAAVFLASQL
Mb1334|M.bovis_AF2122/97 ATGPVRMLASRLGAVAYPRERDVHVTPTPRMGGLAMFLGIVGAVFLASQL
Rv1302|M.tuberculosis_H37Rv ATGPVRMLASRLGAVAYPRERDVHVTPTPRMGGLAMFLGIVGAVFLASQL
MAV_1519|M.avium_104 ATGPVRVLATRLGAVAYPRERDVHVTPTPRMGGLAMFLGVVCAVFLASQL
MLBr_01137|M.leprae_Br4923 ATGLVGVLANRLEAVAYPRERDVHVTPTPRMGGLAMYLGVLAAVFLASQL
MAB_1445|M.abscessus_ATCC_1997 CTGGVRMFATRVGAVAYPRERDVHLQPTPRMGGLGMYFGVCAAIFLASQL
.** * ::* * ***********: * .*****.*::*: *::*****
Mflv_2310|M.gilvum_PYR-GCK PALTRGFVYSSGLPAVVVAGGLIMVVGLIDDRWGLDALTKFAGQITAASV
Mvan_4336|M.vanbaalenii_PYR-1 PALTRGFVYSSGMPAVVVAGGLIMVVGLIDDRWGLDALTKFAGQITAASV
MSMEG_4947|M.smegmatis_MC2_155 PALTRGFVYSTGMPAVVVAGGLIMAIGLIDDRWGLDALTKFAGQITAASV
TH_1564|M.thermoresistible__bu PALTRGFVYSSGMPAVVVAGGLIMAIGLIDDRWGLDALTKFAGQITAASV
MUL_3962|M.ulcerans_Agy99 PALTRGFVYSTGMPAVLVAGAVIMGIGLIDDRWGLDALTKFAGQITAASV
MMAR_4095|M.marinum_M PALTRGFVYSTGMPAVLVAGAVIMGIGLIDDRWGLDALTKFAGQITAASV
Mb1334|M.bovis_AF2122/97 PALTRGFVYSTGMPAVLVAGAVIMGIGLIDDRWGLDALTKFAGQITAASV
Rv1302|M.tuberculosis_H37Rv PALTRGFVYSTGMPAVLVAGAVIMGIGLIDDRWGLDALTKFAGQITAASV
MAV_1519|M.avium_104 PALTRGFVYSSGMPAVLVAGAVIMGIGLIDDRWGLDALTKFAGQITAASV
MLBr_01137|M.leprae_Br4923 PALTRGFVYSSGMPAVLVAGAVITGIGLIDDRWGLDALTKFAGQITAASV
MAB_1445|M.abscessus_ATCC_1997 PALTRGFVYSSGMPAVVVAGGIIMIVGLIDDKWGLDALTKFAGQVTAASV
**********:*:***:***.:* :*****:************:*****
Mflv_2310|M.gilvum_PYR-GCK LVTMGVAWSVLYIPIGGVGTIVLDQVASILLTLAFTVALVNSMNFVDGLD
Mvan_4336|M.vanbaalenii_PYR-1 LVTMGVAWSVLYIPIGGVGTIVLDQVASILLTLALTVAIVNAMNFVDGLD
MSMEG_4947|M.smegmatis_MC2_155 LVTMGVAWSVLYIPIGGVGTIVLDQVSSILLTLALTVSIINAMNFVDGLD
TH_1564|M.thermoresistible__bu LVTMGVAWSVLYIPIGGVGTIVLDQVSSILLTLALTVAVVNAMNFVDGLD
MUL_3962|M.ulcerans_Agy99 LVTMGVAWSVLYIPLGGVGTIVLDQASSILLTLALTVSIVNAMNFVDGLD
MMAR_4095|M.marinum_M LVTMGVAWSVLYIPLGGVGTIVLDQASSILLTLALTVSIVNAMNFVDGLD
Mb1334|M.bovis_AF2122/97 LVTMGVAWSVLYIPVGGVGTIVLDQASSILLTLALTVSIVNAMNFVDGLD
Rv1302|M.tuberculosis_H37Rv LVTMGVAWSVLYIPVGGVGTIVLDQASSILLTLALTVSIVNAMNFVDGLD
MAV_1519|M.avium_104 LVTMGVAWSVLYIPIGGVGTIVLDQASSILLTLALTVSVVNAMNFVDGLD
MLBr_01137|M.leprae_Br4923 LVTMGVAWSVLYIPLGGVGTIVLDQTSSILLTLALTVSIVNAINFVDGLD
MAB_1445|M.abscessus_ATCC_1997 LVTMGVAWSMIYIPFGGVGTIVLDQMSSILVTLALTVSIVNAMNFVDGLD
*********::***.********** :***:***:**:::*::*******
Mflv_2310|M.gilvum_PYR-GCK GLAAGLGLITASAICLFSVGLLHDHGGDVLFYPPAVISVVLAGACLGFLP
Mvan_4336|M.vanbaalenii_PYR-1 GLAAGLGLITASAICIFSVGLLRDHGGDVLFYPPAVISVVLAGVCLGFLP
MSMEG_4947|M.smegmatis_MC2_155 GLAAGLGLITALAICVFSVGLLRDHGGDVLFYPPAVISVVLAGACLGFLP
TH_1564|M.thermoresistible__bu GLAAGLGLITASAICIFSIGLLRDHGGDVLFYPPAVISVVLAGACLGFLP
MUL_3962|M.ulcerans_Agy99 GLAAGLGLITALAICTFSVGLLRDHGGDVLFYPPAVISVVLAGACLGFLP
MMAR_4095|M.marinum_M GLAAGLGLITALAICTFSVGLLRDHGGDVLFYPPAVISVVLAGACLGFLP
Mb1334|M.bovis_AF2122/97 GLAAGLGLITALAICMFSVGLLRDHGGDVLYYPPAVISVVLAGACLGFLP
Rv1302|M.tuberculosis_H37Rv GLAAGLGLITALAICMFSVGLLRDHGGDVLYYPPAVISVVLAGACLGFLP
MAV_1519|M.avium_104 GLAAGLGLITALAICMFSVGLLRDHGGDVLFYPPAVISVVLAGACLGFLP
MLBr_01137|M.leprae_Br4923 GLAAGLGLITAMAICIFSVGLLRDHDGDVLFYPPAVISVVLAGSCLGFLP
MAB_1445|M.abscessus_ATCC_1997 GLAAGLGLITAAAICIFSIGLLRSHGGDVLYYPPAVISVVLAGACLGFLP
*********** *** **:***:.*.****:************ ******
Mflv_2310|M.gilvum_PYR-GCK HNFHKARIFMGDSGSMLIGLMLAAAATTAAGPISQTAYGARDVFALLSPF
Mvan_4336|M.vanbaalenii_PYR-1 HNFHKARIFMGDSGSMLIGLMLAAASTTAAGPISQTAYGARDVFALLSPF
MSMEG_4947|M.smegmatis_MC2_155 HNFHRAKIFMGDSGSMLIGLMLGAASTTAAGPISQNAYGARDVFALLSPF
TH_1564|M.thermoresistible__bu HNFHRAKIFMGDSGSMLIGLMLAAASTTAAGPISQSAYGARDVFALLSPF
MUL_3962|M.ulcerans_Agy99 HNFHRAKIFMGDSGSMLVGLMLAAASTTAAGPISQNAYGARDVFALLSPF
MMAR_4095|M.marinum_M HNFHRAKIFMGDSGSMLVGLMLAAASTTAAGPISQNAYGARDVFALLSPF
Mb1334|M.bovis_AF2122/97 HNFHRAKIFMGDSGSMLIGLMLAAASTTAAGPISQNAYGARDVFALLSPF
Rv1302|M.tuberculosis_H37Rv HNFHRAKIFMGDSGSMLIGLMLAAASTTAAGPISQNAYGARDVFALLSPF
MAV_1519|M.avium_104 HNFHRAKIFMGDSGSMLIGLMLAAASTTAAGPVSQNAYGARDVFALLSPF
MLBr_01137|M.leprae_Br4923 HNFHRAKIFMGDSGSMLVGLMLAAASTTAAGPISQNAYGTRDVFALLSPF
MAB_1445|M.abscessus_ATCC_1997 HNFHRARIFMGDSGSMLIGLMLAAASTTAAGPISQSSYGAKDMFVLLSPF
****:*:**********:****.**:******:**.:**::*:*.*****
Mflv_2310|M.gilvum_PYR-GCK LLVVAVVFVPALDMLLAIIRRTRKGLSPFSPDKMHLHHRLLEIGHSHRRV
Mvan_4336|M.vanbaalenii_PYR-1 LLVVAVMFVPALDMLLAIIRRTRKGLSPFSPDKMHLHHRLLEIGHSHRRV
MSMEG_4947|M.smegmatis_MC2_155 LLVVAVMLVPALDTLLAIVRRTRAGRSPLSPDKMHLHHRLLQIGHSHRRA
TH_1564|M.thermoresistible__bu LLVIAVVLVPALDMLLAIVRRTRAGRSPFSPDKMHIHHRLLQIGHSHRRV
MUL_3962|M.ulcerans_Agy99 LLVVAVMFVPMLDLLLAIVRRTRAGRSAFSPDKMHLHHRLLQIGHSHRRV
MMAR_4095|M.marinum_M LLVVAVMFVPMLDLLLAIVRRTRAGRSAFSPDKMHLHHRLLQIGHSHRRV
Mb1334|M.bovis_AF2122/97 LLVVAVMFVPMLDLLLAIVRRTRAGRSAFSPDKMHLHHRLLQIGHSHRRV
Rv1302|M.tuberculosis_H37Rv LLVVAVMFVPMLDLLLAIVRRTRAGRSAFSPDKMHLHHRLLQIGHSHRRV
MAV_1519|M.avium_104 LLVAAVIFVPMLDLLLAIVRRTRAGRSAFSPDKMHLHHRLLQIGHSHRRV
MLBr_01137|M.leprae_Br4923 LLVVAVMFVPMLDLLLAIVRRIRAGRSAFSPDKMHLHHRLLQIGHSHRRV
MAB_1445|M.abscessus_ATCC_1997 LLVIAVMLVPALDALLAIIRRTRAGRSPFSPDKMHLHHRLLQIGHSHRKA
*** **::** ** ****:** * * *.:******:*****:******:.
Mflv_2310|M.gilvum_PYR-GCK VLLIYLWVGIVAIGAASTIFVDPKHTAIVMAVAIVVAIVVTLIPLLKRGN
Mvan_4336|M.vanbaalenii_PYR-1 VLLIYLWVGIAALGAASSIFFDPRRTAAVMGGAILIAIVVTLIPLLRRGN
MSMEG_4947|M.smegmatis_MC2_155 VLLIYLWVGIIAFGAASTIFFDPGQTAMVMGVAIVVAIVVTLIPLLRRGP
TH_1564|M.thermoresistible__bu VLLIYLWVGIVALGAASTIFFDPKHTGAVMLAAIVVALVVTLIPLLRRGS
MUL_3962|M.ulcerans_Agy99 VLLIYLWVGIVAFGAASTIFVDPRHTAAVMLGALVVAGVVTAIPLLRRRD
MMAR_4095|M.marinum_M VLLIYLWVGIVAFGAASTIFVDPRHTAAVMLGALVVAGVVTAIPLLRRRD
Mb1334|M.bovis_AF2122/97 VLIIYLWVGIGAFGAASSIFFNPRDTAAVMLGAIVVAGVATLIPLLRRGD
Rv1302|M.tuberculosis_H37Rv VLIIYLWVGIVAFGAASSIFFNPRDTAAVMLGAIVVAGVATLIPLLRRGD
MAV_1519|M.avium_104 VLLIYLWVGIVAFGAASTIFFRPRDTAAVMLGAIVVAGIATAIPLLRRGD
MLBr_01137|M.leprae_Br4923 VLLIYLWVGIVAFGAASTIFFNPRNTGAVMLGAIVITGMATVIPLLRRRD
MAB_1445|M.abscessus_ATCC_1997 VLIIYLWVAIIAFGAASTIFFEPRYAGAVVVGAIGIAIVATVIPLLRRED
**:*****.* *:****:**. * :. *: *: :: :.* ****:*
Mflv_2310|M.gilvum_PYR-GCK DE-------------ADSVYDEK
Mvan_4336|M.vanbaalenii_PYR-1 SA-------------AAEVYDEK
MSMEG_4947|M.smegmatis_MC2_155 DG-------------AQEP----
TH_1564|M.thermoresistible__bu ND-------------YEQMYDSK
MUL_3962|M.ulcerans_Agy99 DY-------------YDPD----
MMAR_4095|M.marinum_M DY-------------YDPD----
Mb1334|M.bovis_AF2122/97 DY-------------YDPDLD--
Rv1302|M.tuberculosis_H37Rv DY-------------YDPDLD--
MAV_1519|M.avium_104 DY-------------EDEEYDRQ
MLBr_01137|M.leprae_Br4923 NY---------------------
MAB_1445|M.abscessus_ATCC_1997 TDPALATAPDSSPGTEPVVYDEK