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VTPADLAELLKATAAAVLAERGLDASALPQMVTVERPRIPEHGDYASNLAMQLAKKVGTNPRELAGWLAE ALTKVDGIASAEVAGPGFINMRLETAAQAKVVTSVIDAGHSYGHSLLLAGRKVNLEFVSANPTGPIHIGG TRWAAVGDALGRLLTTQGADVVREYYFNDHGAQIDRFANSLIAAAKGEPTPQDGYAGSYITNIAEQVLQK APDALSLPDAELRETFRAIGVDLMFDHIKQSLHEFGTDFDVYTHEDSMHTGGRVENAIARLRETGNIYEK DGATWLRTSAFGDDKDRVVIKSDGKPAYIAGDLAYYLDKRQRGFDLCIYMLGADHHGYIARLKAAAAAFG DDPATVEVLIGQMVNLVRDGQPVRMSKRAGTVLTLDDLVEAIGVDAARYSLIRSSVDTAIDIDLALWSSA SNENPVYYVQYAHARLSALARNAAELALIPDTNHLELLNHDKEGTLLRTLGEFPRVLETAASLREPHRVC RYLEDLAGDYHRFYDSCRVLPQGDEQPTDLHTARLALCQATRQVIANGLAIIGVTAPERM
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. tuberculosis H37Rv | Rv1292 | argS | - | 100% (550) | arginyl-tRNA synthetase |
M. tuberculosis H37Rv | Rv2448c | valS | 2e-05 | 29.24% (171) | valyl-tRNA synthetase |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb1324 | argS | 0.0 | 100.00% (550) | arginyl-tRNA synthetase |
M. gilvum PYR-GCK | Mflv_2296 | argS | 0.0 | 83.09% (550) | arginyl-tRNA synthetase |
M. leprae Br4923 | MLBr_01127 | argS | 0.0 | 85.09% (550) | arginyl-tRNA synthetase |
M. abscessus ATCC 19977 | MAB_1433 | argS | 0.0 | 76.00% (550) | arginyl-tRNA synthetase |
M. marinum M | MMAR_4105 | argS | 0.0 | 88.55% (550) | arginyl-tRNA synthetase ArgS |
M. avium 104 | MAV_1724 | valS | 3e-05 | 28.07% (171) | valyl-tRNA synthetase |
M. smegmatis MC2 155 | MSMEG_4959 | argS | 0.0 | 82.73% (550) | arginyl-tRNA synthetase |
M. thermoresistible (build 8) | TH_2006 | argS | 0.0 | 82.36% (550) | PROBABLE ARGINYL-TRNA SYNTHETASE ARGS (ARGRS) |
M. ulcerans Agy99 | MUL_3972 | argS | 0.0 | 87.64% (550) | arginyl-tRNA synthetase |
M. vanbaalenii PYR-1 | Mvan_4350 | argS | 0.0 | 84.18% (550) | arginyl-tRNA synthetase |
CLUSTAL 2.0.9 multiple sequence alignment Rv1292|M.tuberculosis_H37Rv --MTPADLAELLK----ATAAAVLAERGLDASALPQMVTVERPRI----- Mb1324|M.bovis_AF2122/97 --MTPADLAELLK----ATAAAVLAERGLDASALPQMVTVERPRI----- MMAR_4105|M.marinum_M --MTPADLAELLK----STATAVLSEHALDTSALPQTVVVERPRN----- MUL_3972|M.ulcerans_Agy99 --MTPADLAELLK----TTATAVLSEHALDTSALPQTVVVERPRN----- MLBr_01127|M.leprae_Br4923 --MTPADLAELLK----TTAIVVLAERGLDAAALPQTVTVERPRN----- Mflv_2296|M.gilvum_PYR-GCK --MTPADLAQLLK----ATAAAVLAEHGLDSAALPDTVTVERPRN----- Mvan_4350|M.vanbaalenii_PYR-1 --MTPADLAELLK----ATAAAVLAEHGLDSAALPAIVTVERPRN----- MSMEG_4959|M.smegmatis_MC2_155 --MTPADLAELLK----ATAAAVLTEHDLDVAALPATVTVERPRN----- TH_2006|M.thermoresistible__bu --VTPADLAELLK----TTTVAVLAERDLDTAAVPATVTVERPRN----- MAB_1433|M.abscessus_ATCC_1997 --MTPADLADLLR----STATTVLDERGLDTSALPAVVTVERPRN----- MAV_1724|M.avium_104 MTASRSPATDLPKSWDPAAAEYAIYRQWVDAGYFTANPASDKPGYSIVLP : : ::* : ::: .: .: :* . .. . ::* Rv1292|M.tuberculosis_H37Rv PEHGDYASNLAMQLAKKVGTNPRELAGWLAEALTKVDGIASAEVAGPGFI Mb1324|M.bovis_AF2122/97 PEHGDYASNLAMQLAKKVGTNPRELAGWLAEALTKVDGIASAEVAGPGFI MMAR_4105|M.marinum_M PEHGDYASNVALQLAKKVGANPRELAGWIAEALTKADGIASAEVAGPGFI MUL_3972|M.ulcerans_Agy99 PEHGDYASNVALQLAKKVGANPRELAGWIVEALTKADGIASAEVAGPGFI MLBr_01127|M.leprae_Br4923 PEHGDYSSNLAMQLGKKVGANPLELAGWLAEVLAQAGGIADVEVAGPGFI Mflv_2296|M.gilvum_PYR-GCK PEHGDYATNLALQLGKKVGANPRELAGWLAEALAASDGIAAADVAGPGFV Mvan_4350|M.vanbaalenii_PYR-1 PEHGDYATNLALQLGKKVGANPRELAGWLAAALVAKDGIAAADVAGPGFV MSMEG_4959|M.smegmatis_MC2_155 PEHGDYATNLALQLGKKVGVNPRELAGWLATALTAADGIAVAEVAGPGFV TH_2006|M.thermoresistible__bu PEHGDYATNIALQLGKKVGVNPRELAGWLAAALAEADGIAAAEVAGPGFV MAB_1433|M.abscessus_ATCC_1997 PEHGDYATNVALQVAKKVGVAPRDLAGWLVEALVSHAAIAGAEIAGPGFV MAV_1724|M.avium_104 PPNVTGSLHMGHALEHTMMDALTRRKRMQGYEVLWQPGMDHAGIATQSVV * : : ::. : :.: : .: . :* ..: Rv1292|M.tuberculosis_H37Rv NMRLETA----------------------AQAKVVTSVIDAGHSYGHS-- Mb1324|M.bovis_AF2122/97 NMRLETA----------------------AQAKVVTSVIDAGHSYGHS-- MMAR_4105|M.marinum_M NLRLETS----------------------AQAKIVNAIIDAGSGFGHS-- MUL_3972|M.ulcerans_Agy99 NLRLETS----------------------AQAKIVNAIIDAGSGFGHS-- MLBr_01127|M.leprae_Br4923 NMRLDAS----------------------AQAMIVNTVINADKNFGHS-- Mflv_2296|M.gilvum_PYR-GCK NLRIEAS----------------------AQNVMVSNVLSAGADYGHS-- Mvan_4350|M.vanbaalenii_PYR-1 NLRIEAS----------------------AQNVIVGDVIAAGATYGAS-- MSMEG_4959|M.smegmatis_MC2_155 NLRIEAS----------------------AQGVIITNVLAAEGSYGSS-- TH_2006|M.thermoresistible__bu NLRIDAT----------------------AQGAIVATVLRQGARYGHS-- MAB_1433|M.abscessus_ATCC_1997 NLRIAAD----------------------AQGTIVANILKAGETYGNS-- MAV_1724|M.avium_104 EKQLAVDGKTKEDFGRELFIEKVWDWKRESGGAIGGQMRRLGDGVDWSRD : :: . : : : . * Rv1292|M.tuberculosis_H37Rv ----LLLAGRKVNLEFVSANPTGPIHIGG--TRWAAVGDALGRLLTTQGA Mb1324|M.bovis_AF2122/97 ----LLLAGRKVNLEFVSANPTGPIHIGG--TRWAAVGDALGRLLTTQGA MMAR_4105|M.marinum_M ----ELMAAHKVNLEFVSANPTGPIHIGG--TRWAAVGDALGRLLSTQGA MUL_3972|M.ulcerans_Agy99 ----ELMAAHKVNLEFVSANPTGPIHIGG--TRWAAVGDALGRLLSTQGA MLBr_01127|M.leprae_Br4923 ----DDLAGYQINLEFVSANPTGPIHIGG--TRWAAVGDALGRLLSTQGA Mflv_2296|M.gilvum_PYR-GCK ----AVLAGKKVNLEFVSANPTGPIHIGG--TRWAAVGDALGRLLTTQGA Mvan_4350|M.vanbaalenii_PYR-1 ----GELDGRRVNLEFVSANPTGPIHIGG--TRWAAVGDALGRLLSTQGA MSMEG_4959|M.smegmatis_MC2_155 ----DQYAGRNVNLEFVSANPTGPIHIGG--TRWAAVGDALGRLLATQGA TH_2006|M.thermoresistible__bu ----DTLAGRKINLEFVSANPTGPIHIGG--TRWAAVGDALGRLLTTQGA MAB_1433|M.abscessus_ATCC_1997 ----DAQGTHTINLEFVSANPTGPIHIGG--TRWAAVGDALGRLLARQGA MAV_1724|M.avium_104 RFTMDEGLSRAVRTIFKRLYDAGLIYRAERLVNWSPVLQTALSDIEVNYE :. * :* *: . ..*:.* :: : : Rv1292|M.tuberculosis_H37Rv DVVREYYFNDHGAQIDRFANSLIAAAKGEPTPQDGYAGSYITNIAEQVLQ Mb1324|M.bovis_AF2122/97 DVVREYYFNDHGAQIDRFANSLIAAAKGEPTPQDGYAGSYITNIAEQVLQ MMAR_4105|M.marinum_M DVVREYYFNDHGAQIDRFANSLIAAAKGEPTPDDGYAGTYINDIAARVLQ MUL_3972|M.ulcerans_Agy99 DVVREYYFNDHGAQIDRFANSLIAAAKGEPTPDDGYAGSYINDIAARVLQ MLBr_01127|M.leprae_Br4923 AVVREYYFNDHGAQIDRFTNSLIAAAKGELTPADGYAGTYVTDIAAQVMQ Mflv_2296|M.gilvum_PYR-GCK AVTREYYFNDHGAQIDRFSNSLIAAAKGEPAPEDGYAGTYIADIASQVVA Mvan_4350|M.vanbaalenii_PYR-1 EVVREYYFNDHGAQIDRFTNSLIAAAKGEPAPEDGYAGTYIADIAAQVLA MSMEG_4959|M.smegmatis_MC2_155 AVTREYYFNDHGAQIDRFVNSLIASAKGEPTPEDGYAGDYIVDIAQQVIA TH_2006|M.thermoresistible__bu DVTREYYFNDHGAQIDRFAKSLIAAAKGEPTPEDGYAGEYIQEIAAAVLA MAB_1433|M.abscessus_ATCC_1997 KVTREYYFNDHGAQIDRFVRSLIASAEGKEAPEDGYAGDYIADIAKQVIT MAV_1724|M.avium_104 EVEGELVSFRYGSLDDSGPHIVVATTRVETMLGDTAIAVHPDDERYRHLV * * :*: * . ::*::. : * . : : : Rv1292|M.tuberculosis_H37Rv KA--------PDALSLPDAELRETFRAIGVDLMFDH-------------- Mb1324|M.bovis_AF2122/97 KA--------PDALSLPDAELRETFRAIGVDLMFDH-------------- MMAR_4105|M.marinum_M KA--------PDALSLPDAQMHETFREIGVDLMFSH-------------- MUL_3972|M.ulcerans_Agy99 KA--------PDALSLPDAQMHETFREIGVDLMFSH-------------- MLBr_01127|M.leprae_Br4923 QA--------PYALSLPESEMHETVREIGVDLMFTH-------------- Mflv_2296|M.gilvum_PYR-GCK KE--------PGVLDQPDDRMRETFRAIGVNLMFDH-------------- Mvan_4350|M.vanbaalenii_PYR-1 KE--------PGALELPDAEMRETFRAVGVNLMFDH-------------- MSMEG_4959|M.smegmatis_MC2_155 KA--------PDVLGLPEDQQRETFRAIGVDLMFTH-------------- TH_2006|M.thermoresistible__bu KE--------PQALSLPDDEMHETFRSIGVDLMFAH-------------- MAB_1433|M.abscessus_ATCC_1997 QR--------PEALTLTEPERSEVFREIGVDLMFTH-------------- MAV_1724|M.avium_104 GSSLPHPFVDRQLLIVADEHVDPEFGTGAVKVTPAHDPNDFEIGLRHQLP * .: . . .*.: * Rv1292|M.tuberculosis_H37Rv ------IKQSLHEFGTDFD-------VYTHEDSMHTGGRVENAIARLRET Mb1324|M.bovis_AF2122/97 ------IKQSLHEFGTDFD-------VYTHEDSMHTGGRVENAIARLRET MMAR_4105|M.marinum_M ------IKESLHEFGTDFD-------VYTHEDSMHSTGRVDQAVARLRET MUL_3972|M.ulcerans_Agy99 ------IKESLHEFGTDFD-------VYTHEDSMHSTGRVDQAVARLRET MLBr_01127|M.leprae_Br4923 ------IKKSLHEFGTDFD-------VYTHEDSMHASGRVDEAIARLRDT Mflv_2296|M.gilvum_PYR-GCK ------IKESLHEFGTDFD-------VYTHEDSMHTSGRVEQAIDKLRET Mvan_4350|M.vanbaalenii_PYR-1 ------IKESLHEFGTDFD-------VYTHEDSMHTSGRVDQAIAKLRET MSMEG_4959|M.smegmatis_MC2_155 ------IKQSLHDFGTDFD-------VYTHEDSMHTSGRVDQAITQLREA TH_2006|M.thermoresistible__bu ------IKQSLHEFGTDFD-------VYTHEESMHTSGRVDQAIARLREA MAB_1433|M.abscessus_ATCC_1997 ------IKESLHEFGTDFD-------VFTHEDSMHTSGRVQEAIAQLRKT MAV_1724|M.avium_104 MISIMDTKGRIADTGTQFDGMDRFAARVAVREALAAQGRIVEEKRPYLHS * : : **:** : .::: : **: : .: Rv1292|M.tuberculosis_H37Rv GNIYEKDG---------ATWLRTSAFGDDK-------DRVVIKSDGKP-- Mb1324|M.bovis_AF2122/97 GNIYEKDG---------ATWLRTSAFGDDK-------DRVVIKSDGKP-- MMAR_4105|M.marinum_M GNIYEKDG---------ATWLRSSSFGDDK-------DRVVIKSDGKP-- MUL_3972|M.ulcerans_Agy99 GNIYEKDG---------ATWLRSSSFGDDK-------DRVVIKSDDKP-- MLBr_01127|M.leprae_Br4923 GNVYEKDG---------ALWLRTSAFGDDK-------DRVVIKSDGKP-- Mflv_2296|M.gilvum_PYR-GCK GFAYEKDG---------AVWLRTTDFGDDK-------DRVVIKSDGKP-- Mvan_4350|M.vanbaalenii_PYR-1 GSIYEKDG---------AVWLRTTDFGDDK-------DRVVIKSDGQP-- MSMEG_4959|M.smegmatis_MC2_155 GSIYEKDG---------AVWLRTTDFGDDK-------DRVVIKSDGNA-- TH_2006|M.thermoresistible__bu GAIYEKDG---------AVWLRTTDYGDDK-------DRVVIKSDGQP-- MAB_1433|M.abscessus_ATCC_1997 GNIYEKDG---------ASWLRSSNFGDDK-------DRVVIKSDGNP-- MAV_1724|M.avium_104 VGHSERSGEPIEPRLSLQWWVRVESLAKAAGDAVRNGDTVIHPTSMEPRW *:.* *:* .. * *: :. :. Rv1292|M.tuberculosis_H37Rv -AYIAGDLAYYLD-KRQRGFDLCIYMLGADHHGYIARLKAAAAAFGDDPA Mb1324|M.bovis_AF2122/97 -AYIAGDLAYYLD-KRQRGFDLCIYMLGADHHGYIARLKAAAAAFGDDPA MMAR_4105|M.marinum_M -AYIAGDLAYYLD-KRERGFDLCIYMLGADHHGYIARLKAAAAAFGEDPA MUL_3972|M.ulcerans_Agy99 -AYIAGDLAYYLD-KRERGFDLCIYMLGADHHGYIARLKAAAAAFGEDPG MLBr_01127|M.leprae_Br4923 -AYIAGDLAYYLD-KRQRGFDLCIYMLGADHHGYIARLKAAAAAFGDDPA Mflv_2296|M.gilvum_PYR-GCK -AYIAGDLAYFLD-KRKRGFDLCIYMLGADHHGYIARLKASAAALGDDPD Mvan_4350|M.vanbaalenii_PYR-1 -AYIAGDLAYFLD-KRKRGFDLCIYMLGADHHGYIARLKAAAAALGDDPD MSMEG_4959|M.smegmatis_MC2_155 -AYIAGDLAYYLD-KRKRGFDLCIYMLGADHHGYIARLKAAAAALGDDPD TH_2006|M.thermoresistible__bu -AYIAGDLAYYLD-KRERGFDLCIYMLGADHHGYVTRLKAAAAAFGDDPD MAB_1433|M.abscessus_ATCC_1997 -AYIAGDIAYYLD-KRERGFDLCIYMLGADHHGYIARLKAVAAALGYDAD MAV_1724|M.avium_104 FAWVDDMHDWCISRQLWWGHRIPIWYGPNGEQRCVGPDETPPEGWEQDPD *:: . : :. : *. : *: ..: : :: . . *. Rv1292|M.tuberculosis_H37Rv TVEVLIG------------------------------------------- Mb1324|M.bovis_AF2122/97 TVEVLIG------------------------------------------- MMAR_4105|M.marinum_M TVEVLIG------------------------------------------- MUL_3972|M.ulcerans_Agy99 TVEVLIG------------------------------------------- MLBr_01127|M.leprae_Br4923 IVEVLIG------------------------------------------- Mflv_2296|M.gilvum_PYR-GCK TVEVLIG------------------------------------------- Mvan_4350|M.vanbaalenii_PYR-1 TVEVLIG------------------------------------------- MSMEG_4959|M.smegmatis_MC2_155 TVEVLIG------------------------------------------- TH_2006|M.thermoresistible__bu TVEVLIG------------------------------------------- MAB_1433|M.abscessus_ATCC_1997 SVEVLIG------------------------------------------- MAV_1724|M.avium_104 VLDTWFSSALWPFSTLGWPEKTPELEKFYPTSVLVTGYDILFFWVARMMM ::. :. Rv1292|M.tuberculosis_H37Rv --------------------------QMVNLVRDGQPVRMSKRAGTVLTL Mb1324|M.bovis_AF2122/97 --------------------------QMVNLVRDGQPVRMSKRAGTVLTL MMAR_4105|M.marinum_M --------------------------QMVNLVRDGQPVRMSKRAGTVITL MUL_3972|M.ulcerans_Agy99 --------------------------QMVNLVRDGQPVRMSKRTGTVITL MLBr_01127|M.leprae_Br4923 --------------------------QMVNLVCDGQLVRMSKRSGNVITL Mflv_2296|M.gilvum_PYR-GCK --------------------------QMVNLVRDGQPVRMSKRAGTVITL Mvan_4350|M.vanbaalenii_PYR-1 --------------------------QMVNLVRDGQPVRMSKRAGTVITL MSMEG_4959|M.smegmatis_MC2_155 --------------------------QMVNLVRDGQPVRMSKRAGTVITL TH_2006|M.thermoresistible__bu --------------------------QMVNLVRDGQPVRMSKRAGTVITL MAB_1433|M.abscessus_ATCC_1997 --------------------------QMVNLVRDGQPVRMSKRAGTVITL MAV_1724|M.avium_104 FGTFVGDDDAITLDGRRGPQVPFTDVFLHGLIRDESGRKMSKSKGNVIDP : .*: * . :*** *.*: Rv1292|M.tuberculosis_H37Rv DDLVEAIGVDAARYSLIR-------------------------------- Mb1324|M.bovis_AF2122/97 DDLVEAIGVDAARYSLIR-------------------------------- MMAR_4105|M.marinum_M DDLVEAIGVDAARYSLIR-------------------------------- MUL_3972|M.ulcerans_Agy99 DDLVEAIGVDAARYSLIR-------------------------------- MLBr_01127|M.leprae_Br4923 DDLVEAIGVDAARYSLIR-------------------------------- Mflv_2296|M.gilvum_PYR-GCK DDLVEAIGVDAARYSLIR-------------------------------- Mvan_4350|M.vanbaalenii_PYR-1 DDLVDAIGVDAARYALIR-------------------------------- MSMEG_4959|M.smegmatis_MC2_155 DDLVEAIGVDAARYALIR-------------------------------- TH_2006|M.thermoresistible__bu DDLVEAIGVDAARYALIR-------------------------------- MAB_1433|M.abscessus_ATCC_1997 DDLVDAIGVDAARYALIR-------------------------------- MAV_1724|M.avium_104 LDWVDMFGADALRFTLARGASPGGDLAIGEDHVRASRNFCTKLFNATRYA * *: :*.** *::* * Rv1292|M.tuberculosis_H37Rv -------------------------------SSVDTAID------IDLAL Mb1324|M.bovis_AF2122/97 -------------------------------SSVDTAID------IDLAL MMAR_4105|M.marinum_M -------------------------------SSVDTPID------IDLAL MUL_3972|M.ulcerans_Agy99 -------------------------------SSVDTPID------IDLAL MLBr_01127|M.leprae_Br4923 -------------------------------SSVDTPID------IDLAL Mflv_2296|M.gilvum_PYR-GCK -------------------------------SSVDTPID------IDLEL Mvan_4350|M.vanbaalenii_PYR-1 -------------------------------SSVDTPID------IDLAL MSMEG_4959|M.smegmatis_MC2_155 -------------------------------SSVDTPID------IDLEL TH_2006|M.thermoresistible__bu -------------------------------SSVDTPID------IDLEL MAB_1433|M.abscessus_ATCC_1997 -------------------------------SSVDTSID------IDLEL MAV_1724|M.avium_104 LLNGAQLAQLPPLDELTDADRWILGRLEEVRAEVDSAFDNYEFSRACESL :.**:.:* * Rv1292|M.tuberculosis_H37Rv WSSASNENPVYYVQYAHARLSALARNAAELALIPDTNHLELLN------- Mb1324|M.bovis_AF2122/97 WSSASNENPVYYVQYAHARLSALARNAAELALIPDTNHLELLN------- MMAR_4105|M.marinum_M WSSASNENPVYYVQYAHARLSALARNAAELGLIPDTDHLELLS------- MUL_3972|M.ulcerans_Agy99 WSSASNENPVYYVQYAHARLSALARNAAELGLIPDTDHLELLS------- MLBr_01127|M.leprae_Br4923 WSSSSNENPVYYVQYAHARLSALARNAAEFGLIPDTGHLELLS------- Mflv_2296|M.gilvum_PYR-GCK WSSASNENPVYYVQYAHARLSALARNAAELGIAPDTAHLDLLT------- Mvan_4350|M.vanbaalenii_PYR-1 WSSASNENPVYYVQYAHARLSALARNAAELGVAADTAHLDLLT------- MSMEG_4959|M.smegmatis_MC2_155 WSSASNENPVYYVQYAHARLCALARNAADLGVSVNTDHLDLLT------- TH_2006|M.thermoresistible__bu WSSATNENPVYYVQYAHARLSALARNAADLGVTPSTEHLDLLT------- MAB_1433|M.abscessus_ATCC_1997 WASASSENPVYYVQYAHARLCALARNAADLGLQHSTEHLELLT------- MAV_1724|M.avium_104 YHFAWDEFCDWYVELAKTQLAEGITHTTAVLATTLDTLLRLLHPVIPFIT : : .* :**: *:::*. ::: . * ** Rv1292|M.tuberculosis_H37Rv ----HDKEGTLLRTLGEFP-------------------------RVLETA Mb1324|M.bovis_AF2122/97 ----HDKEGTLLRTLGEFP-------------------------RVLETA MMAR_4105|M.marinum_M ----HEKEGVLLRTLGDFP-------------------------RMLKTA MUL_3972|M.ulcerans_Agy99 ----HEKEGVLLRTLGDFP-------------------------RMLKAA MLBr_01127|M.leprae_Br4923 ----HDKEGALLRTVGEFP-------------------------QVLKTA Mflv_2296|M.gilvum_PYR-GCK ----HDKEGVLIRNIGEFP-------------------------RILATA Mvan_4350|M.vanbaalenii_PYR-1 ----HDKEGTLIRNIGEFP-------------------------RVLKTA MSMEG_4959|M.smegmatis_MC2_155 ----HEKEGALIRNLGEFP-------------------------RVLKTA TH_2006|M.thermoresistible__bu ----HDKEGTLIRTIGEFP-------------------------RILKTA MAB_1433|M.abscessus_ATCC_1997 ----HEKEGALIRGLGEFG-------------------------RILQNA MAV_1724|M.avium_104 EALWQALTGNESLVIADWPRSSGVGLDQVATQRITDMQKLVTEVRRFRSD : * :.:: : : Rv1292|M.tuberculosis_H37Rv ASLREPHRVCRYLEDL--------------------AGDYHRFYDSCRVL Mb1324|M.bovis_AF2122/97 ASLREPHRVCRYLEDL--------------------AGDYHRFYDSCRVL MMAR_4105|M.marinum_M ASLREPHRVCRYLEDL--------------------AGDYHRFYDSCRVL MUL_3972|M.ulcerans_Agy99 ASLREPHRVCRYLEDL--------------------AGDYHRFYDSCRVL MLBr_01127|M.leprae_Br4923 AALREPHRVCRYLEDL--------------------AGDYHRFYDSCRVL Mflv_2296|M.gilvum_PYR-GCK AELREPHRVSRYLEDL--------------------AGDYHRFYDACRVL Mvan_4350|M.vanbaalenii_PYR-1 ASLREPHRVSRYLEDL--------------------AGDYHRFYDSCRVL MSMEG_4959|M.smegmatis_MC2_155 ASLREPHRVCRYLEDL--------------------AGDYHRFYDSCRVL TH_2006|M.thermoresistible__bu AALREPHRVSRYLEDL--------------------AGAYHRFYDSCRVL MAB_1433|M.abscessus_ATCC_1997 AALREPHRVARYLEDI--------------------AGDYHRFYDSCRVL MAV_1724|M.avium_104 QGLADRQKVPARLAGVTESDLDTQVSAVTSLAWLTDAGPDFRPSASVEVR * : ::* * .: ** .* : .* Rv1292|M.tuberculosis_H37Rv PQGDEQPTDLHTARLALCQATRQVIANGLAIIGVTAPERM---------- Mb1324|M.bovis_AF2122/97 PQGDEQPTDLHTARLALCQATRQVIANGLAIIGVTAPERM---------- MMAR_4105|M.marinum_M PQGDEEPTQLHTARLALCQATRQVIANGLGILGVTAPERM---------- MUL_3972|M.ulcerans_Agy99 PQGDEEPTQLHTARLALCQATRQAIANGLGILGVTAPERM---------- MLBr_01127|M.leprae_Br4923 PQGDEKPTDLHTARLALCQANRQVIANGLAILGVSAPERM---------- Mflv_2296|M.gilvum_PYR-GCK PQGDEAPGDLHAARLALCAATRQVIANGLDILGVSAPERM---------- Mvan_4350|M.vanbaalenii_PYR-1 PQGDETPGDLHAARLALCAATRQVIANGLGILGVSAPERM---------- MSMEG_4959|M.smegmatis_MC2_155 PQGDEEPGDLHSARLALCRATRQVIANGLAILGVSAPERM---------- TH_2006|M.thermoresistible__bu PQGDEEPTELHAARLALCEATRQVIANGLGILGVSAPERM---------- MAB_1433|M.abscessus_ATCC_1997 PQGDETPGDLHAARLALCLATRQVIANGLDILGVSAPERM---------- MAV_1724|M.avium_104 LRGGTVVVELDTSGSIDVAAERRRLEKDLAAAHKELASTTAKLANEDFLA :*. :*.:: * *: : :.* .. Rv1292|M.tuberculosis_H37Rv -------------------------------- Mb1324|M.bovis_AF2122/97 -------------------------------- MMAR_4105|M.marinum_M -------------------------------- MUL_3972|M.ulcerans_Agy99 -------------------------------- MLBr_01127|M.leprae_Br4923 -------------------------------- Mflv_2296|M.gilvum_PYR-GCK -------------------------------- Mvan_4350|M.vanbaalenii_PYR-1 -------------------------------- MSMEG_4959|M.smegmatis_MC2_155 -------------------------------- TH_2006|M.thermoresistible__bu -------------------------------- MAB_1433|M.abscessus_ATCC_1997 -------------------------------- MAV_1724|M.avium_104 KAPPHVVDKIRDRQRLAQEESERINARLAVLQ