For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MLRLVVGALLLVLAFAGGYAVAACKTVTLTVDGTAMRVTTMKSRVIDIVEENGFSVDDRDDLYPAAGVQV HDADTIVLRRSRPLQISLDGHDAKQVWTTASTVDEALAQLAMTDTAPAAASRASRVPLSGMALPVVSAKT VQLNDGGLVRTVHLPAPNVAGLLSAAGVPLLQSDHVVPAATAPIVEGMQIQVTRNRIKKVTERLPLPPNA RRVEDPEMNMSREVVEDPGVPGTQDVTFAVAEVNGVETGRLPVANVVVTPAHEAVVRVGTKPGTEVPPVI DGSIWDAIAGCEAGGNWAINTGNGYYGGVQFDQGTWEANGGLRYAPRADLATREEQIAVAEVTRLRQGWG AWPVCAARAGAR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv1009 | rpfB | - | 100% (362) | Probable resuscitation-promoting factor rpfB |
| M. tuberculosis H37Rv | Rv0867c | rpfA | 2e-24 | 50.00% (108) | resuscitation-promoting factor RpfA |
| M. tuberculosis H37Rv | Rv2450c | rpfE | 7e-23 | 59.55% (89) | resuscitation-promoting factor RpfE |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1036 | rpfB | 0.0 | 99.45% (362) | resuscitation-promoting factor rpfB |
| M. gilvum PYR-GCK | Mflv_1932 | - | 1e-148 | 71.19% (361) | transglycosylase domain-containing protein |
| M. leprae Br4923 | MLBr_00240 | - | 1e-173 | 82.27% (361) | hypothetical protein MLBr_00240 |
| M. abscessus ATCC 19977 | MAB_1130 | - | 1e-137 | 64.92% (362) | hypothetical protein MAB_1130 |
| M. marinum M | MMAR_4479 | rpfB | 1e-176 | 85.04% (361) | resuscitation-promoting factor RpfB |
| M. avium 104 | MAV_1147 | - | 1e-173 | 86.14% (339) | resuscitation-promoting factor RpfB |
| M. smegmatis MC2 155 | MSMEG_5439 | - | 1e-161 | 77.07% (362) | resuscitation-promoting factor RpfB |
| M. thermoresistible (build 8) | TH_0979 | - | 1e-156 | 74.24% (361) | Probable resuscitation-promoting factor rpfB |
| M. ulcerans Agy99 | MUL_4651 | rpfB | 1e-175 | 84.21% (361) | resuscitation-promoting factor RpfB |
| M. vanbaalenii PYR-1 | Mvan_4801 | - | 1e-154 | 73.96% (361) | transglycosylase domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1932|M.gilvum_PYR-GCK MNALIKLHQTRSPLLRCVVAGILLALVFAGGTAVATHKTVTLEVDGASVT
Mvan_4801|M.vanbaalenii_PYR-1 MNALIKLHQTRSPLLRVLVAATLLALIVAGGTAVAAHKTVTLTVDDVSMA
TH_0979|M.thermoresistible__bu VNVLHKIHENPSPALRLVVGALLVVLAAAGGYAVSAHKTVTLSVDGAPMT
MSMEG_5439|M.smegmatis_MC2_155 MEALNKLHESRSPLLRGVVGAFLVSLTVAGSYAVASHKTVTLSVDGAPMT
Rv1009|M.tuberculosis_H37Rv -------------MLRLVVGALLLVLAFAGGYAVAACKTVTLTVDGTAMR
Mb1036|M.bovis_AF2122/97 -------------MLRLVVGALLLVLAFAGGYAVAACKTVTLTVDGTAMR
MMAR_4479|M.marinum_M -------------MLRAVVGALLVGLALAGGYAVSASKTVTLTVDGTAMR
MUL_4651|M.ulcerans_Agy99 -------------MLRAVVGALLVGLALAGGYAVSASKTVTLTVDGTAMR
MLBr_00240|M.leprae_Br4923 MNVLTRLHETSSPIFRLVVGVLLLVIAFAGGYAVAAYKTVTLTVDGTPMQ
MAV_1147|M.avium_104 -----------------------------------MCKTVTLTVDGVAMR
MAB_1130|M.abscessus_ATCC_1997 MNALTKLNATRSPLLRALVAALLVVIGAGGGYAIAAHKTLTLNVDGNAMT
**:** **. .:
Mflv_1932|M.gilvum_PYR-GCK VPTMKSRVIDVVTENGFDVGERDDLYPAADTPVNQSDTIVLRRSRPLEIS
Mvan_4801|M.vanbaalenii_PYR-1 VPTMKSRVIDVVEENGFEVGERDDLYPAADTPVHHSDTIVLRRSRPLEIS
TH_0979|M.thermoresistible__bu VSTMKSRVIDVVEENGFTVGERDDLFPAAGERISADDTIVLRRSRPLEIS
MSMEG_5439|M.smegmatis_MC2_155 VTTMKSRVIDIVEENGFEVSDRDDLFPAATETVHQSDTIVLRRSRPLEVS
Rv1009|M.tuberculosis_H37Rv VTTMKSRVIDIVEENGFSVDDRDDLYPAAGVQVHDADTIVLRRSRPLQIS
Mb1036|M.bovis_AF2122/97 VTTMKSRVIDIVEENGFSVDDRDDLYPAAGVQVHDADTIVLRRSRPLQIS
MMAR_4479|M.marinum_M VTTMKSRVIDIVQENGYSVGDRDDLYPAAEVAVHNADTIVLRRSRPLEIS
MUL_4651|M.ulcerans_Agy99 VTTMKSRVIDIVQENGYSVGDGDDLYPAAEVAVHNAETIVLRRSRPLEIS
MLBr_00240|M.leprae_Br4923 VMTMKSRVIDIIQENGFAVGECDDLYPAADVSVHATDNIVLRRSRPLQIS
MAV_1147|M.avium_104 VTTMKSKVIDVVEENGFVVDDRDDLYPAADVAVHDAGKIVLRRSRPLQIS
MAB_1130|M.abscessus_ATCC_1997 VTTVKSRVSEVLADYGYALSDRDDVAPAKHDSVRDGDTIVLKRSRPLDIS
* *:**:* ::: : *: :.: **: ** : .***:*****::*
Mflv_1932|M.gilvum_PYR-GCK TDGGGTEQVWTTASTVDEALAQLQMTDKAPVAASRASRLPLDGMELPVVS
Mvan_4801|M.vanbaalenii_PYR-1 TDGGGTEQVWTTASTVDQALAQLQMTDKAPVAASRGSRLPLDGMALPVVS
TH_0979|M.thermoresistible__bu LDGQKSEQVWTTASTVDEALAQLSMADKAPAAASRASRVPLAGMSLPVVS
MSMEG_5439|M.smegmatis_MC2_155 LDGEGTKQVWTTASTVDEALAQLRMTDKAPAAASRGSRVPLAGMALPVVS
Rv1009|M.tuberculosis_H37Rv LDGHDAKQVWTTASTVDEALAQLAMTDTAPAAASRASRVPLSGMALPVVS
Mb1036|M.bovis_AF2122/97 LDGHDAKQVWTTASTVDEALAQLAMTDTAPAAASRASRVPLSGMALPVVS
MMAR_4479|M.marinum_M LDGHQVKKVWTTASTVDEALAQLAMTDTAPATASRGSRVPLAGMALPVVS
MUL_4651|M.ulcerans_Agy99 LDGHQVKKVWTTASTVDEALAQLAMTDTAPATASRGSRVPLAGMALPVVS
MLBr_00240|M.leprae_Br4923 LDGKDIQQVWTTASTVDEALVQLALTDTAPIVASRGSRVPLTGMALPVVS
MAV_1147|M.avium_104 LDGHDTKQVWTTASTVDEALAQLAMTDTAPAAANRGSRVPLAGMALPVVS
MAB_1130|M.abscessus_ATCC_1997 VDGQDTQQVWTTASTVNDALSQLSMTDTAPTAATRGSRLPLEGMSLAVVS
** ::********::** ** ::*.** .*.*.**:** ** *.***
Mflv_1932|M.gilvum_PYR-GCK PRNVQIEDAGQMRFVRLAAPNVGALLEASGAPLQQSDAVIPAASTPITDG
Mvan_4801|M.vanbaalenii_PYR-1 PKNVQIDDGGAVRAVRLAAPNVASLLDAAGVPLQQSDTVIPAASSPVVEG
TH_0979|M.thermoresistible__bu PKTVHINDGGELRTVHLAAPTVANLLEAAGAPLEQQDKVSPPPSAPVTDG
MSMEG_5439|M.smegmatis_MC2_155 PKTVQIDDGGKVSTVHLAAPNVAGLLEAAGVPLEQNDKVVPAASSPVVDG
Rv1009|M.tuberculosis_H37Rv AKTVQLNDGGLVRTVHLPAPNVAGLLSAAGVPLLQSDHVVPAATAPIVEG
Mb1036|M.bovis_AF2122/97 AKTVQLNDGGLVRTVHLPAPNVAGLLSAAGVPLLQSDHVVPAATAPIVEG
MMAR_4479|M.marinum_M AKNVQINDGGVVRSVHLPAANVAALLSAAGAPLQGNDQVVPSAATPIVDG
MUL_4651|M.ulcerans_Agy99 AKNVQINDGGVVRSVHLPAVNVAALLSAAGAPLQGNDQVAPSAATPIVDG
MLBr_00240|M.leprae_Br4923 AKTVQINDGGAVRMVHLPASNVGGLLAAVGIPLLASDQVSPSATSPIVEG
MAV_1147|M.avium_104 AKTVRINDGGAVRTVHLAAPNVAGLLSAAGAPLAESDQVAPPASAPIVDG
MAB_1130|M.abscessus_ATCC_1997 AKTVQLNDGGVISTPRIAAPTVGALLEATGNPLQQFDTVDPAPSTPVTAD
.:.*:::*.* : ::.* .*. ** * * ** * * *..::*:. .
Mflv_1932|M.gilvum_PYR-GCK MHIRVTRVRVAKVTERLPLNPNNQRVEDVNLNMSRQIVENPGVPGVQDVT
Mvan_4801|M.vanbaalenii_PYR-1 MRITVTRVRVAKVTERLPLMPNNQRIDDVTLNMSRQIVEDPGNPGVQDVT
TH_0979|M.thermoresistible__bu MHVEVTRVRVEKVTERLPLAPNNRRIEDETLNKSRTIVEDPGRPGVQDVT
MSMEG_5439|M.smegmatis_MC2_155 MQIQVTRMRIEKVTERVPLAPGNERIEDPTMNMSRQVVEDPGAPGLQDVT
Rv1009|M.tuberculosis_H37Rv MQIQVTRNRIKKVTERLPLPPNARRVEDPEMNMSREVVEDPGVPGTQDVT
Mb1036|M.bovis_AF2122/97 MQIQVTRNRIKKVTERLPLPPNARRVEDPEMNMSREVVEDPGVPGTQDVT
MMAR_4479|M.marinum_M MQIEVTRNRIERVTERVELPPPARRIEDPEMNISREVVEDPGAPGTQDVT
MUL_4651|M.ulcerans_Agy99 MQIEVTRNRIERVTERVELPPPARRIEDPEMNISREVVEDPGAPGTQDVT
MLBr_00240|M.leprae_Br4923 MQIQVTRNRIERVIERIPLPPSSRSIEDPEMNISRVVVEDPGTPGTQDVT
MAV_1147|M.avium_104 MEIQVTRNRIQQVTERMPLPPNARRIEDPDMNMSRQVVEDPGSPGTQDVT
MAB_1130|M.abscessus_ATCC_1997 MPITVTRIRVSKVTEQAPLAPTPQKIEDPEMNMSRSVVQDPGAPGTQDIV
* : *** *: :* *: * * . ::* :* ** :*::** ** **:.
Mflv_1932|M.gilvum_PYR-GCK FAVSTINGVETGRLPVANVVITPAVDGVLRVGAKPGTEVPEVRNGGTWDA
Mvan_4801|M.vanbaalenii_PYR-1 FAVATVNGVETGRLPVANVVIAPARDGVLRVGAKPGTEVPPVSNGGTWDA
TH_0979|M.thermoresistible__bu FAVSKVNGVETGRLPVANVIVEPARDGVLRVGAKPGTEVPPITNLAIWEA
MSMEG_5439|M.smegmatis_MC2_155 FAIAKVNGVETGRLPVANQVIEPARNGVLRVGAKPGTEVPPVSNGHTWDA
Rv1009|M.tuberculosis_H37Rv FAVAEVNGVETGRLPVANVVVTPAHEAVVRVGTKPGTEVPPVIDGSIWDA
Mb1036|M.bovis_AF2122/97 FAVAEVNGVETGRLPVANVVVTPAHEAVVRVGTKPGTEVPPVIDESIWDA
MMAR_4479|M.marinum_M FAVAEVNGVVTGKLPVANVVITPAREAVVRVGTKPGTEVPVVIDGSIWDA
MUL_4651|M.ulcerans_Agy99 FAVAEVNGVVTGKLPVANVVITPAREAVVRVGTKPGTEVPVVIDGSVWDA
MLBr_00240|M.leprae_Br4923 FAVATVNGVETGRLPVANVVVEPARESVIRVGTKPGTEVPPVSDGSIWDA
MAV_1147|M.avium_104 FSVATVNGVETGRLPIANTVITPARESVVRVGTKPGTEVPPISDGSIWDA
MAB_1130|M.abscessus_ATCC_1997 YSVLSVNGRETGRMPVSNNVLTPARDSVLRVGAKPGTEVPAVTRGSAWDA
::: :** **::*::* :: ** :.*:***:******* : *:*
Mflv_1932|M.gilvum_PYR-GCK LARCEAGGNWSINTGNGYFGGVQFDQNTWERNGGLRYAQRADLATREEQI
Mvan_4801|M.vanbaalenii_PYR-1 LARCEAGGNWAINTGNGYFGGVQFDQNTWERNGGLRYAQRADLATREEQI
TH_0979|M.thermoresistible__bu LARCEAGGNWAINTGNGYYGGVQFDQNTWERNGGLRYAPRADLATKEEQI
MSMEG_5439|M.smegmatis_MC2_155 LAQCEAGGNWAINTGNGFYGGVQFDQNTWERNGGLRYAPRADLATREEQI
Rv1009|M.tuberculosis_H37Rv IAGCEAGGNWAINTGNGYYGGVQFDQGTWEANGGLRYAPRADLATREEQI
Mb1036|M.bovis_AF2122/97 IAGCEAGGNWAINTGNGYYGGVQFDQGTWEANGGLRYAPRADLATREEQI
MMAR_4479|M.marinum_M IAGCEAGGNWAINTGNGYFGGVQFDQGTWVANGGLRYAERADLATREEQI
MUL_4651|M.ulcerans_Agy99 IAGCEAGGNWAINTGNGYYGGVQFDQGTWVANGGLRYAERADLATREEQI
MLBr_00240|M.leprae_Br4923 IAGCEAGGNWAINTGNGYYGGVQFDQGTWVANGGLRYAPRADLATREEQI
MAV_1147|M.avium_104 IAGCEAGGNWAINTGNGYYGGVQFDQGTWERNGGLRFAPRADLATREEQI
MAB_1130|M.abscessus_ATCC_1997 LAQCEAGGNWAINTGNGFYGGVQFDYGTWLAHGGGKYAPRADLATREEQI
:* *******:******::****** .** :** ::* ******:****
Mflv_1932|M.gilvum_PYR-GCK AIAEVTRARQGWGAWPTCSGRIGAS
Mvan_4801|M.vanbaalenii_PYR-1 AIAEVTRARQGWGAWPTCSGRIGAS
TH_0979|M.thermoresistible__bu AIAEVTRARQGWGAWPTCSARLGVR
MSMEG_5439|M.smegmatis_MC2_155 AIATVTQSRQGWGAWPVCSGRIGAR
Rv1009|M.tuberculosis_H37Rv AVAEVTRLRQGWGAWPVCAARAGAR
Mb1036|M.bovis_AF2122/97 AVAEVTRLRQGWGAWPVCAVRAGAR
MMAR_4479|M.marinum_M AVAEVTRQRQGWGAWPVCSGRAGAH
MUL_4651|M.ulcerans_Agy99 AVAEVTRQRQGWGAWPVCSGRAGAH
MLBr_00240|M.leprae_Br4923 AVAEVTRARQGWDAWPVCSGRVGAH
MAV_1147|M.avium_104 TVAEVTRERQGWGAWPVCSGRAGAR
MAB_1130|M.abscessus_ATCC_1997 AIAEKTLSAQGWGAWPVCSARVGAR
::* * ***.***.*: * *.