For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
NALIKLHQTRSPLLRVLVAATLLALIVAGGTAVAAHKTVTLTVDDVSMAVPTMKSRVIDVVEENGFEVGE RDDLYPAADTPVHHSDTIVLRRSRPLEISTDGGGTEQVWTTASTVDQALAQLQMTDKAPVAASRGSRLPL DGMALPVVSPKNVQIDDGGAVRAVRLAAPNVASLLDAAGVPLQQSDTVIPAASSPVVEGMRITVTRVRVA KVTERLPLMPNNQRIDDVTLNMSRQIVEDPGNPGVQDVTFAVATVNGVETGRLPVANVVIAPARDGVLRV GAKPGTEVPPVSNGGTWDALARCEAGGNWAINTGNGYFGGVQFDQNTWERNGGLRYAQRADLATREEQIA IAEVTRARQGWGAWPTCSGRIGAS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_4801 | - | - | 100% (375) | transglycosylase domain-containing protein |
| M. vanbaalenii PYR-1 | Mvan_5049 | - | 8e-26 | 62.50% (80) | FHA domain-containing protein |
| M. vanbaalenii PYR-1 | Mvan_3962 | - | 1e-20 | 43.44% (122) | transglycosylase domain-containing protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1036 | rpfB | 1e-152 | 73.68% (361) | resuscitation-promoting factor rpfB |
| M. gilvum PYR-GCK | Mflv_1932 | - | 0.0 | 86.67% (375) | transglycosylase domain-containing protein |
| M. tuberculosis H37Rv | Rv1009 | rpfB | 1e-154 | 73.96% (361) | resuscitation-promoting factor rpfB |
| M. leprae Br4923 | MLBr_00240 | - | 1e-155 | 70.86% (374) | hypothetical protein MLBr_00240 |
| M. abscessus ATCC 19977 | MAB_1130 | - | 1e-138 | 63.90% (374) | hypothetical protein MAB_1130 |
| M. marinum M | MMAR_4479 | rpfB | 1e-149 | 71.47% (361) | resuscitation-promoting factor RpfB |
| M. avium 104 | MAV_1147 | - | 1e-148 | 75.37% (337) | resuscitation-promoting factor RpfB |
| M. smegmatis MC2 155 | MSMEG_5439 | - | 1e-171 | 78.88% (374) | resuscitation-promoting factor RpfB |
| M. thermoresistible (build 8) | TH_0979 | - | 1e-162 | 75.34% (373) | Probable resuscitation-promoting factor rpfB |
| M. ulcerans Agy99 | MUL_4651 | rpfB | 1e-147 | 70.64% (361) | resuscitation-promoting factor RpfB |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_4801|M.vanbaalenii_PYR-1 MNALIKLHQTRSPLLRVLVAATLLALIVAGGTAVAAHKTVTLTVDDVSMA
Mflv_1932|M.gilvum_PYR-GCK MNALIKLHQTRSPLLRCVVAGILLALVFAGGTAVATHKTVTLEVDGASVT
TH_0979|M.thermoresistible__bu VNVLHKIHENPSPALRLVVGALLVVLAAAGGYAVSAHKTVTLSVDGAPMT
MSMEG_5439|M.smegmatis_MC2_155 MEALNKLHESRSPLLRGVVGAFLVSLTVAGSYAVASHKTVTLSVDGAPMT
MMAR_4479|M.marinum_M -------------MLRAVVGALLVGLALAGGYAVSASKTVTLTVDGTAMR
MUL_4651|M.ulcerans_Agy99 -------------MLRAVVGALLVGLALAGGYAVSASKTVTLTVDGTAMR
MLBr_00240|M.leprae_Br4923 MNVLTRLHETSSPIFRLVVGVLLLVIAFAGGYAVAAYKTVTLTVDGTPMQ
Mb1036|M.bovis_AF2122/97 -------------MLRLVVGALLLVLAFAGGYAVAACKTVTLTVDGTAMR
Rv1009|M.tuberculosis_H37Rv -------------MLRLVVGALLLVLAFAGGYAVAACKTVTLTVDGTAMR
MAV_1147|M.avium_104 -----------------------------------MCKTVTLTVDGVAMR
MAB_1130|M.abscessus_ATCC_1997 MNALTKLNATRSPLLRALVAALLVVIGAGGGYAIAAHKTLTLNVDGNAMT
**:** **. .:
Mvan_4801|M.vanbaalenii_PYR-1 VPTMKSRVIDVVEENGFEVGERDDLYPAADTPVHHSDTIVLRRSRPLEIS
Mflv_1932|M.gilvum_PYR-GCK VPTMKSRVIDVVTENGFDVGERDDLYPAADTPVNQSDTIVLRRSRPLEIS
TH_0979|M.thermoresistible__bu VSTMKSRVIDVVEENGFTVGERDDLFPAAGERISADDTIVLRRSRPLEIS
MSMEG_5439|M.smegmatis_MC2_155 VTTMKSRVIDIVEENGFEVSDRDDLFPAATETVHQSDTIVLRRSRPLEVS
MMAR_4479|M.marinum_M VTTMKSRVIDIVQENGYSVGDRDDLYPAAEVAVHNADTIVLRRSRPLEIS
MUL_4651|M.ulcerans_Agy99 VTTMKSRVIDIVQENGYSVGDGDDLYPAAEVAVHNAETIVLRRSRPLEIS
MLBr_00240|M.leprae_Br4923 VMTMKSRVIDIIQENGFAVGECDDLYPAADVSVHATDNIVLRRSRPLQIS
Mb1036|M.bovis_AF2122/97 VTTMKSRVIDIVEENGFSVDDRDDLYPAAGVQVHDADTIVLRRSRPLQIS
Rv1009|M.tuberculosis_H37Rv VTTMKSRVIDIVEENGFSVDDRDDLYPAAGVQVHDADTIVLRRSRPLQIS
MAV_1147|M.avium_104 VTTMKSKVIDVVEENGFVVDDRDDLYPAADVAVHDAGKIVLRRSRPLQIS
MAB_1130|M.abscessus_ATCC_1997 VTTVKSRVSEVLADYGYALSDRDDVAPAKHDSVRDGDTIVLKRSRPLDIS
* *:**:* ::: : *: :.: **: ** : .***:*****::*
Mvan_4801|M.vanbaalenii_PYR-1 TDGGGTEQVWTTASTVDQALAQLQMTDKAPVAASRGSRLPLDGMALPVVS
Mflv_1932|M.gilvum_PYR-GCK TDGGGTEQVWTTASTVDEALAQLQMTDKAPVAASRASRLPLDGMELPVVS
TH_0979|M.thermoresistible__bu LDGQKSEQVWTTASTVDEALAQLSMADKAPAAASRASRVPLAGMSLPVVS
MSMEG_5439|M.smegmatis_MC2_155 LDGEGTKQVWTTASTVDEALAQLRMTDKAPAAASRGSRVPLAGMALPVVS
MMAR_4479|M.marinum_M LDGHQVKKVWTTASTVDEALAQLAMTDTAPATASRGSRVPLAGMALPVVS
MUL_4651|M.ulcerans_Agy99 LDGHQVKKVWTTASTVDEALAQLAMTDTAPATASRGSRVPLAGMALPVVS
MLBr_00240|M.leprae_Br4923 LDGKDIQQVWTTASTVDEALVQLALTDTAPIVASRGSRVPLTGMALPVVS
Mb1036|M.bovis_AF2122/97 LDGHDAKQVWTTASTVDEALAQLAMTDTAPAAASRASRVPLSGMALPVVS
Rv1009|M.tuberculosis_H37Rv LDGHDAKQVWTTASTVDEALAQLAMTDTAPAAASRASRVPLSGMALPVVS
MAV_1147|M.avium_104 LDGHDTKQVWTTASTVDEALAQLAMTDTAPAAANRGSRVPLAGMALPVVS
MAB_1130|M.abscessus_ATCC_1997 VDGQDTQQVWTTASTVNDALSQLSMTDTAPTAATRGSRLPLEGMSLAVVS
** ::********::** ** ::*.** .*.*.**:** ** *.***
Mvan_4801|M.vanbaalenii_PYR-1 PKNVQIDDGGAVRAVRLAAPNVASLLDAAGVPLQQSDTVIPAASSPVVEG
Mflv_1932|M.gilvum_PYR-GCK PRNVQIEDAGQMRFVRLAAPNVGALLEASGAPLQQSDAVIPAASTPITDG
TH_0979|M.thermoresistible__bu PKTVHINDGGELRTVHLAAPTVANLLEAAGAPLEQQDKVSPPPSAPVTDG
MSMEG_5439|M.smegmatis_MC2_155 PKTVQIDDGGKVSTVHLAAPNVAGLLEAAGVPLEQNDKVVPAASSPVVDG
MMAR_4479|M.marinum_M AKNVQINDGGVVRSVHLPAANVAALLSAAGAPLQGNDQVVPSAATPIVDG
MUL_4651|M.ulcerans_Agy99 AKNVQINDGGVVRSVHLPAVNVAALLSAAGAPLQGNDQVAPSAATPIVDG
MLBr_00240|M.leprae_Br4923 AKTVQINDGGAVRMVHLPASNVGGLLAAVGIPLLASDQVSPSATSPIVEG
Mb1036|M.bovis_AF2122/97 AKTVQLNDGGLVRTVHLPAPNVAGLLSAAGVPLLQSDHVVPAATAPIVEG
Rv1009|M.tuberculosis_H37Rv AKTVQLNDGGLVRTVHLPAPNVAGLLSAAGVPLLQSDHVVPAATAPIVEG
MAV_1147|M.avium_104 AKTVRINDGGAVRTVHLAAPNVAGLLSAAGAPLAESDQVAPPASAPIVDG
MAB_1130|M.abscessus_ATCC_1997 AKTVQLNDGGVISTPRIAAPTVGALLEATGNPLQQFDTVDPAPSTPVTAD
.:.*:::*.* : ::.* .*. ** * * ** * * *..::*:. .
Mvan_4801|M.vanbaalenii_PYR-1 MRITVTRVRVAKVTERLPLMPNNQRIDDVTLNMSRQIVEDPGNPGVQDVT
Mflv_1932|M.gilvum_PYR-GCK MHIRVTRVRVAKVTERLPLNPNNQRVEDVNLNMSRQIVENPGVPGVQDVT
TH_0979|M.thermoresistible__bu MHVEVTRVRVEKVTERLPLAPNNRRIEDETLNKSRTIVEDPGRPGVQDVT
MSMEG_5439|M.smegmatis_MC2_155 MQIQVTRMRIEKVTERVPLAPGNERIEDPTMNMSRQVVEDPGAPGLQDVT
MMAR_4479|M.marinum_M MQIEVTRNRIERVTERVELPPPARRIEDPEMNISREVVEDPGAPGTQDVT
MUL_4651|M.ulcerans_Agy99 MQIEVTRNRIERVTERVELPPPARRIEDPEMNISREVVEDPGAPGTQDVT
MLBr_00240|M.leprae_Br4923 MQIQVTRNRIERVIERIPLPPSSRSIEDPEMNISRVVVEDPGTPGTQDVT
Mb1036|M.bovis_AF2122/97 MQIQVTRNRIKKVTERLPLPPNARRVEDPEMNMSREVVEDPGVPGTQDVT
Rv1009|M.tuberculosis_H37Rv MQIQVTRNRIKKVTERLPLPPNARRVEDPEMNMSREVVEDPGVPGTQDVT
MAV_1147|M.avium_104 MEIQVTRNRIQQVTERMPLPPNARRIEDPDMNMSRQVVEDPGSPGTQDVT
MAB_1130|M.abscessus_ATCC_1997 MPITVTRIRVSKVTEQAPLAPTPQKIEDPEMNMSRSVVQDPGAPGTQDIV
* : *** *: :* *: * * . ::* :* ** :*::** ** **:.
Mvan_4801|M.vanbaalenii_PYR-1 FAVATVNGVETGRLPVANVVIAPARDGVLRVGAKPGTEVPPVSNGGTWDA
Mflv_1932|M.gilvum_PYR-GCK FAVSTINGVETGRLPVANVVITPAVDGVLRVGAKPGTEVPEVRNGGTWDA
TH_0979|M.thermoresistible__bu FAVSKVNGVETGRLPVANVIVEPARDGVLRVGAKPGTEVPPITNLAIWEA
MSMEG_5439|M.smegmatis_MC2_155 FAIAKVNGVETGRLPVANQVIEPARNGVLRVGAKPGTEVPPVSNGHTWDA
MMAR_4479|M.marinum_M FAVAEVNGVVTGKLPVANVVITPAREAVVRVGTKPGTEVPVVIDGSIWDA
MUL_4651|M.ulcerans_Agy99 FAVAEVNGVVTGKLPVANVVITPAREAVVRVGTKPGTEVPVVIDGSVWDA
MLBr_00240|M.leprae_Br4923 FAVATVNGVETGRLPVANVVVEPARESVIRVGTKPGTEVPPVSDGSIWDA
Mb1036|M.bovis_AF2122/97 FAVAEVNGVETGRLPVANVVVTPAHEAVVRVGTKPGTEVPPVIDESIWDA
Rv1009|M.tuberculosis_H37Rv FAVAEVNGVETGRLPVANVVVTPAHEAVVRVGTKPGTEVPPVIDGSIWDA
MAV_1147|M.avium_104 FSVATVNGVETGRLPIANTVITPARESVVRVGTKPGTEVPPISDGSIWDA
MAB_1130|M.abscessus_ATCC_1997 YSVLSVNGRETGRMPVSNNVLTPARDSVLRVGAKPGTEVPAVTRGSAWDA
::: :** **::*::* :: ** :.*:***:******* : *:*
Mvan_4801|M.vanbaalenii_PYR-1 LARCEAGGNWAINTGNGYFGGVQFDQNTWERNGGLRYAQRADLATREEQI
Mflv_1932|M.gilvum_PYR-GCK LARCEAGGNWSINTGNGYFGGVQFDQNTWERNGGLRYAQRADLATREEQI
TH_0979|M.thermoresistible__bu LARCEAGGNWAINTGNGYYGGVQFDQNTWERNGGLRYAPRADLATKEEQI
MSMEG_5439|M.smegmatis_MC2_155 LAQCEAGGNWAINTGNGFYGGVQFDQNTWERNGGLRYAPRADLATREEQI
MMAR_4479|M.marinum_M IAGCEAGGNWAINTGNGYFGGVQFDQGTWVANGGLRYAERADLATREEQI
MUL_4651|M.ulcerans_Agy99 IAGCEAGGNWAINTGNGYYGGVQFDQGTWVANGGLRYAERADLATREEQI
MLBr_00240|M.leprae_Br4923 IAGCEAGGNWAINTGNGYYGGVQFDQGTWVANGGLRYAPRADLATREEQI
Mb1036|M.bovis_AF2122/97 IAGCEAGGNWAINTGNGYYGGVQFDQGTWEANGGLRYAPRADLATREEQI
Rv1009|M.tuberculosis_H37Rv IAGCEAGGNWAINTGNGYYGGVQFDQGTWEANGGLRYAPRADLATREEQI
MAV_1147|M.avium_104 IAGCEAGGNWAINTGNGYYGGVQFDQGTWERNGGLRFAPRADLATREEQI
MAB_1130|M.abscessus_ATCC_1997 LAQCEAGGNWAINTGNGFYGGVQFDYGTWLAHGGGKYAPRADLATREEQI
:* *******:******::****** .** :** ::* ******:****
Mvan_4801|M.vanbaalenii_PYR-1 AIAEVTRARQGWGAWPTCSGRIGAS
Mflv_1932|M.gilvum_PYR-GCK AIAEVTRARQGWGAWPTCSGRIGAS
TH_0979|M.thermoresistible__bu AIAEVTRARQGWGAWPTCSARLGVR
MSMEG_5439|M.smegmatis_MC2_155 AIATVTQSRQGWGAWPVCSGRIGAR
MMAR_4479|M.marinum_M AVAEVTRQRQGWGAWPVCSGRAGAH
MUL_4651|M.ulcerans_Agy99 AVAEVTRQRQGWGAWPVCSGRAGAH
MLBr_00240|M.leprae_Br4923 AVAEVTRARQGWDAWPVCSGRVGAH
Mb1036|M.bovis_AF2122/97 AVAEVTRLRQGWGAWPVCAVRAGAR
Rv1009|M.tuberculosis_H37Rv AVAEVTRLRQGWGAWPVCAARAGAR
MAV_1147|M.avium_104 TVAEVTRERQGWGAWPVCSGRAGAR
MAB_1130|M.abscessus_ATCC_1997 AIAEKTLSAQGWGAWPVCSARVGAR
::* * ***.***.*: * *.